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The map label for this gene is hisS [H]

Identifier: 91788469

GI number: 91788469

Start: 2737204

End: 2738562

Strand: Reverse

Name: hisS [H]

Synonym: Bpro_2607

Alternate gene names: 91788469

Gene position: 2738562-2737204 (Counterclockwise)

Preceding gene: 91788470

Following gene: 91788468

Centisome position: 52.66

GC content: 61.88

Gene sequence:

>1359_bases
ATGCCTGAAAAAATGAATGCCGGCCAGACGGAGAAATTACCCTTGGCCAAAATCGAAAAACTCACCGCCGTCAAGGGCAT
GAACGACATCTTGCCGCCGGATTCGGCGCGCTGGGAGTGGCTCGAAGACAAAGTCCGCACGCTGATGGGGCGCTATGCCT
ACCGTAATATCCGCACCCCCATTCTTGAGCACACGCAGCTGTTTGTGCGGGGGATTGGCGAGGTCACGGACATCGTCGAA
AAGGAAATGTATTCCTTCGAAGACCGTGCGGACAAGTATGGTGATCATGACCACCTCACCATGCGGCCTGAAAATACCGC
CAGCGTGGTTCGTGCGGTCACCGAACACAACCTGCTCTATGAGGGCGGCAAGCGCCTCTACTATATGGGCCCGATGTTCC
GTCGGGAGCGCCCGCAACGTGGCCGTTACCGCCAGTTTCATCAGATTGGCGCCGAAGCACTGGGTTTTGCCGGACCGGAA
GTGGATGCCGAGCTGATTTTGCTGGCCGCGGCGCTCTGGAAGGAGCTGGGCCTGAGCGATTGGCGCCTGGAAATCAATAG
CCTGGGTCAGCCCGATGAGCGTGCCCAGCACCGTGCCCAACTGATCGCCCACCTGGAACAACATGCCGACGTCCTGGACG
AGGAAGCACGCCGGCGCCTGCACAGCAATCCGCTGCGCATTCTTGACACCAAGAATCCGGTCATGCAAGCAGTGGTAGAC
AGCGCCCCCCGGCTGATCGACTTTCTGGGGCCCCAGTCGTTGGCGCATTTTGAGGGACTTAAAGCCATCCTCGATGCCAA
CGGCATCCCCTGGACCCTGAATCCCCGACTGGTGCGCGGGCTGGATTATTACAACCTCACGGTGTTTGAGTTTGTGACCG
ACCGGCTGGGCGCCCAAGGCACCATTTGCGCCGGAGGGCGCTATGACTACCTGATTGAGCAGATGGGCGGCAAAGCCGCG
CCGGCAGTGGGATGGGCCTTGGGCGTAGAGCGTGTGCTGGAGCTCATCAAGGAGCAGGGCGCTGCCGTCACGCCGCCGGT
ACCCGATGCCTATGCGGTGATTCCCGAGGCATCTGCCTTGCCCGTCGTTCTGCAAACCCTGCAGGCCTTGCGCGCGGCGG
GGGTGAGTGTGCAGATGCACGCCGGTGCCAGCGCCGACGGCATGGGCAGCATGAAGTCCCAGTTCAAGAAGGCCGATGGC
AGCGGCGCGCGGTTTGCCCTCATTTTCGGTCCGGCCGAGCTGGCGCAGGGGCACGTTGCCGTCAAACCGCTGCGGGGGGA
AAAGGCTGATGTGGCGCAGGTGCAAACCTTGCAGCCACTGGACGACGTGTCCGCCTGGGCTCACGCCTTGCGCGCCTAG

Upstream 100 bases:

>100_bases
TGCGCGGAGACAACATTGCGCAGGAGTTCCAGGTCATCGTTGAAAACTACATTGAAAAACGCTTTGGCACGCAGTCCGTC
GCCGAAGCCGCGTGAATCCC

Downstream 100 bases:

>100_bases
CCTTGCATTTCGCCCCCCTACAATCACCCCACCTCAATCCGCGCCGTTATCGGGCAGAACAAGCAGACTTTTATGGCAAA
ACATCTCGATTTGGAAGAGC

Product: histidyl-tRNA synthetase

Products: NA

Alternate protein names: Histidine--tRNA ligase; HisRS [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MPEKMNAGQTEKLPLAKIEKLTAVKGMNDILPPDSARWEWLEDKVRTLMGRYAYRNIRTPILEHTQLFVRGIGEVTDIVE
KEMYSFEDRADKYGDHDHLTMRPENTASVVRAVTEHNLLYEGGKRLYYMGPMFRRERPQRGRYRQFHQIGAEALGFAGPE
VDAELILLAAALWKELGLSDWRLEINSLGQPDERAQHRAQLIAHLEQHADVLDEEARRRLHSNPLRILDTKNPVMQAVVD
SAPRLIDFLGPQSLAHFEGLKAILDANGIPWTLNPRLVRGLDYYNLTVFEFVTDRLGAQGTICAGGRYDYLIEQMGGKAA
PAVGWALGVERVLELIKEQGAAVTPPVPDAYAVIPEASALPVVLQTLQALRAAGVSVQMHAGASADGMGSMKSQFKKADG
SGARFALIFGPAELAQGHVAVKPLRGEKADVAQVQTLQPLDDVSAWAHALRA

Sequences:

>Translated_452_residues
MPEKMNAGQTEKLPLAKIEKLTAVKGMNDILPPDSARWEWLEDKVRTLMGRYAYRNIRTPILEHTQLFVRGIGEVTDIVE
KEMYSFEDRADKYGDHDHLTMRPENTASVVRAVTEHNLLYEGGKRLYYMGPMFRRERPQRGRYRQFHQIGAEALGFAGPE
VDAELILLAAALWKELGLSDWRLEINSLGQPDERAQHRAQLIAHLEQHADVLDEEARRRLHSNPLRILDTKNPVMQAVVD
SAPRLIDFLGPQSLAHFEGLKAILDANGIPWTLNPRLVRGLDYYNLTVFEFVTDRLGAQGTICAGGRYDYLIEQMGGKAA
PAVGWALGVERVLELIKEQGAAVTPPVPDAYAVIPEASALPVVLQTLQALRAAGVSVQMHAGASADGMGSMKSQFKKADG
SGARFALIFGPAELAQGHVAVKPLRGEKADVAQVQTLQPLDDVSAWAHALRA
>Mature_451_residues
PEKMNAGQTEKLPLAKIEKLTAVKGMNDILPPDSARWEWLEDKVRTLMGRYAYRNIRTPILEHTQLFVRGIGEVTDIVEK
EMYSFEDRADKYGDHDHLTMRPENTASVVRAVTEHNLLYEGGKRLYYMGPMFRRERPQRGRYRQFHQIGAEALGFAGPEV
DAELILLAAALWKELGLSDWRLEINSLGQPDERAQHRAQLIAHLEQHADVLDEEARRRLHSNPLRILDTKNPVMQAVVDS
APRLIDFLGPQSLAHFEGLKAILDANGIPWTLNPRLVRGLDYYNLTVFEFVTDRLGAQGTICAGGRYDYLIEQMGGKAAP
AVGWALGVERVLELIKEQGAAVTPPVPDAYAVIPEASALPVVLQTLQALRAAGVSVQMHAGASADGMGSMKSQFKKADGS
GARFALIFGPAELAQGHVAVKPLRGEKADVAQVQTLQPLDDVSAWAHALRA

Specific function: Unknown

COG id: COG0124

COG function: function code J; Histidyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1788861, Length=422, Percent_Identity=50.7109004739336, Blast_Score=422, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6325290, Length=478, Percent_Identity=24.2677824267782, Blast_Score=93, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR015807
- InterPro:   IPR004516 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.21 [H]

Molecular weight: Translated: 50056; Mature: 49925

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEKMNAGQTEKLPLAKIEKLTAVKGMNDILPPDSARWEWLEDKVRTLMGRYAYRNIRTP
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
ILEHTQLFVRGIGEVTDIVEKEMYSFEDRADKYGDHDHLTMRPENTASVVRAVTEHNLLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHE
EGGKRLYYMGPMFRRERPQRGRYRQFHQIGAEALGFAGPEVDAELILLAAALWKELGLSD
ECCCEEEEECCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
WRLEINSLGQPDERAQHRAQLIAHLEQHADVLDEEARRRLHSNPLRILDTKNPVMQAVVD
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHH
SAPRLIDFLGPQSLAHFEGLKAILDANGIPWTLNPRLVRGLDYYNLTVFEFVTDRLGAQG
CCHHHHHHHCCHHHHHHHHHHHHHCCCCCCEECCHHHHHCCCHHHHHHHHHHHHHHCCCC
TICAGGRYDYLIEQMGGKAAPAVGWALGVERVLELIKEQGAAVTPPVPDAYAVIPEASAL
EEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHH
PVVLQTLQALRAAGVSVQMHAGASADGMGSMKSQFKKADGSGARFALIFGPAELAQGHVA
HHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEEECHHHHHCCCEE
VKPLRGEKADVAQVQTLQPLDDVSAWAHALRA
EECCCCCCCHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
PEKMNAGQTEKLPLAKIEKLTAVKGMNDILPPDSARWEWLEDKVRTLMGRYAYRNIRTP
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
ILEHTQLFVRGIGEVTDIVEKEMYSFEDRADKYGDHDHLTMRPENTASVVRAVTEHNLLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHE
EGGKRLYYMGPMFRRERPQRGRYRQFHQIGAEALGFAGPEVDAELILLAAALWKELGLSD
ECCCEEEEECCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
WRLEINSLGQPDERAQHRAQLIAHLEQHADVLDEEARRRLHSNPLRILDTKNPVMQAVVD
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHH
SAPRLIDFLGPQSLAHFEGLKAILDANGIPWTLNPRLVRGLDYYNLTVFEFVTDRLGAQG
CCHHHHHHHCCHHHHHHHHHHHHHCCCCCCEECCHHHHHCCCHHHHHHHHHHHHHHCCCC
TICAGGRYDYLIEQMGGKAAPAVGWALGVERVLELIKEQGAAVTPPVPDAYAVIPEASAL
EEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHH
PVVLQTLQALRAAGVSVQMHAGASADGMGSMKSQFKKADGSGARFALIFGPAELAQGHVA
HHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEEECHHHHHCCCEE
VKPLRGEKADVAQVQTLQPLDDVSAWAHALRA
EECCCCCCCHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA