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The map label for this gene is frzCD [H]

Identifier: 91788328

GI number: 91788328

Start: 2568492

End: 2570030

Strand: Direct

Name: frzCD [H]

Synonym: Bpro_2463

Alternate gene names: 91788328

Gene position: 2568492-2570030 (Clockwise)

Preceding gene: 91788327

Following gene: 91788329

Centisome position: 49.39

GC content: 63.29

Gene sequence:

>1539_bases
ATGGACTGGCTTGCAAACGTTCCGATTCGCACCAAACTGCTGCTGATCAGCGTGCTGACCAGCGCGATTGCGCTGCTGCT
GGCCGGTGCGGCCATCATTGTCTACGACACCATCACCTACACCGACCAGAAGAAACGTGAAATATCGGTTCAGGCCGAAA
CGCTTGCCGCCAGCGTCACTGCGGCGCTCGCTTTCAACGACGCGAAAGTGGCCGAGGAATACCTCAAGGCATTCGAAGCG
AATCCGGAAATCGCGGCAGCCGGAATCTACACCACAGATGCCAGGCTCTTTGCCCGATACATGCGTTCCGGCTTATCCAC
CCGGGCGCTGCCCACGGCAGCGGAGCCTGCGGGAGAGCGATTCAAGGACGATGAACTGGAAGTGTTCCGACCCATCAAGG
ACGGCGCTCGCACGGTGGGAACCGTCTACCTGCGTGCGAACACCGAGTCGCTGGCCATCCGTATAGCGCGCTTCGGCGGA
ATCATTCTGCTGGTGCTGGTCGGTTCGCTGGTGATCACGCTACCGATATCCATACGCATGCAACGCGTGATCTCGCACCC
CATCCAGGATATCTCAAGGGCAGCCTCACTCATCGCGGCCGGCGATCTCACGGCGACGCTGCCCGTGCAGCAGCGCTCCG
ATGAGATCGGTTTGCTGGTGGAAATGTTCACCCGCATGGCGGAGGGTCTTCGCGAGCAGATTCGCGGGCTGATCGAAGGC
GCGACGGTGCTGGGTTCGGCCGCCAGCGATATCGTCGCGTCCACCACCCAGCTCTCCGTCAGCGCCAGCGAGTCGGCTGT
GATCGTGAGCGAAACGACCGTCACCGTGGAAGAAGTGCGGCAAACGGCACAAGTGGCCAGCCAGAAAGCCAAAAACGTGG
CCGACAGTGCGCAGAAAGCGGCGCAGATTTCCCAAAACGGGCGCAAGTCCACCGAGGACGTTGCGGCCGGGATGAACCGC
ATCCGGCTGCAGATGGAAGCCATTGCCGTCAGCATGACGCGACTGTCCGAGCAGAGCCAGGCCATAGGCCGGATCATGGC
CACCGTCGAGGACCTCGCTGCGCAATCCAACCTGCTGGCTGTCAACGCGGCCATCGAGGCCGCCAAGGCCGGCGAGCACG
GCAAGGGCTTTGGCGTGGTAGCGCAGGAAGTCAAAAGCCTGGCGGAGCAGTCGCGCCAGGCGACCAACCAGGTGCGCACC
ATCCTGGGGGACATCCAGAAGGCGACGACGACGGCCATGATGGCGACGGAACAGGGCAGCAAGGCGGTAGAGGCGGGAAC
CCGGCAGACCGAAGTGGCGAGCGAGTCAATCCAGGCGCTGACCGCCAGCGTCAACGAGGCGACGCAGGCGGCCACGCAGA
TCGCGGCATCGAGCCAGCAGCAGCTGGTGGGGGTGGACCAGGTGGCGGGCGCGATGGAGAGCATCAAGCAGGCGAGCACG
CAGAACGTAGCCGGCGCCAGGCAGCTGGAAGTTGCGGCGCGCAACCTCAACGAACTCGGCCAGCGGCTCAAGCAGATGGT
CGAACGTTACAAGGTGTAG

Upstream 100 bases:

>100_bases
CGACGACGAAGCCGCCGCGCAGAACAGGCTGGCCATCAGTTCCAAGCTGCTGAGCGTAGCGCTCAGCGTCAAGCCCAGAC
GGGTCGGGGAGGGCCGTTAA

Downstream 100 bases:

>100_bases
TCAACCACAAACGCCATGAGCACCAAAGAAGACAACTTTCTCCAGCCACTCCGCGCGACCTTCCAGGTCAAAGCCACGGA
GCATGAGCAGGCGATCGCAG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MDWLANVPIRTKLLLISVLTSAIALLLAGAAIIVYDTITYTDQKKREISVQAETLAASVTAALAFNDAKVAEEYLKAFEA
NPEIAAAGIYTTDARLFARYMRSGLSTRALPTAAEPAGERFKDDELEVFRPIKDGARTVGTVYLRANTESLAIRIARFGG
IILLVLVGSLVITLPISIRMQRVISHPIQDISRAASLIAAGDLTATLPVQQRSDEIGLLVEMFTRMAEGLREQIRGLIEG
ATVLGSAASDIVASTTQLSVSASESAVIVSETTVTVEEVRQTAQVASQKAKNVADSAQKAAQISQNGRKSTEDVAAGMNR
IRLQMEAIAVSMTRLSEQSQAIGRIMATVEDLAAQSNLLAVNAAIEAAKAGEHGKGFGVVAQEVKSLAEQSRQATNQVRT
ILGDIQKATTTAMMATEQGSKAVEAGTRQTEVASESIQALTASVNEATQAATQIAASSQQQLVGVDQVAGAMESIKQAST
QNVAGARQLEVAARNLNELGQRLKQMVERYKV

Sequences:

>Translated_512_residues
MDWLANVPIRTKLLLISVLTSAIALLLAGAAIIVYDTITYTDQKKREISVQAETLAASVTAALAFNDAKVAEEYLKAFEA
NPEIAAAGIYTTDARLFARYMRSGLSTRALPTAAEPAGERFKDDELEVFRPIKDGARTVGTVYLRANTESLAIRIARFGG
IILLVLVGSLVITLPISIRMQRVISHPIQDISRAASLIAAGDLTATLPVQQRSDEIGLLVEMFTRMAEGLREQIRGLIEG
ATVLGSAASDIVASTTQLSVSASESAVIVSETTVTVEEVRQTAQVASQKAKNVADSAQKAAQISQNGRKSTEDVAAGMNR
IRLQMEAIAVSMTRLSEQSQAIGRIMATVEDLAAQSNLLAVNAAIEAAKAGEHGKGFGVVAQEVKSLAEQSRQATNQVRT
ILGDIQKATTTAMMATEQGSKAVEAGTRQTEVASESIQALTASVNEATQAATQIAASSQQQLVGVDQVAGAMESIKQAST
QNVAGARQLEVAARNLNELGQRLKQMVERYKV
>Mature_512_residues
MDWLANVPIRTKLLLISVLTSAIALLLAGAAIIVYDTITYTDQKKREISVQAETLAASVTAALAFNDAKVAEEYLKAFEA
NPEIAAAGIYTTDARLFARYMRSGLSTRALPTAAEPAGERFKDDELEVFRPIKDGARTVGTVYLRANTESLAIRIARFGG
IILLVLVGSLVITLPISIRMQRVISHPIQDISRAASLIAAGDLTATLPVQQRSDEIGLLVEMFTRMAEGLREQIRGLIEG
ATVLGSAASDIVASTTQLSVSASESAVIVSETTVTVEEVRQTAQVASQKAKNVADSAQKAAQISQNGRKSTEDVAAGMNR
IRLQMEAIAVSMTRLSEQSQAIGRIMATVEDLAAQSNLLAVNAAIEAAKAGEHGKGFGVVAQEVKSLAEQSRQATNQVRT
ILGDIQKATTTAMMATEQGSKAVEAGTRQTEVASESIQALTASVNEATQAATQIAASSQQQLVGVDQVAGAMESIKQAST
QNVAGARQLEVAARNLNELGQRLKQMVERYKV

Specific function: Methyl-accepting taxis protein necessary for the proper aggregation of cells to form fruiting bodies. Frz genes define a system of signal transduction analogous to the enterobacterial chemotaxis systems [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=525, Percent_Identity=28.7619047619048, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788195, Length=303, Percent_Identity=29.042904290429, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI2367378, Length=324, Percent_Identity=27.7777777777778, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788194, Length=336, Percent_Identity=27.3809523809524, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789453, Length=353, Percent_Identity=26.3456090651558, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 54352; Mature: 54352

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWLANVPIRTKLLLISVLTSAIALLLAGAAIIVYDTITYTDQKKREISVQAETLAASVT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHCCCCCHHHHHHHHHHHHHHHHH
AALAFNDAKVAEEYLKAFEANPEIAAAGIYTTDARLFARYMRSGLSTRALPTAAEPAGER
HHHHCCHHHHHHHHHHHHCCCCCEEEECEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
FKDDELEVFRPIKDGARTVGTVYLRANTESLAIRIARFGGIILLVLVGSLVITLPISIRM
CCCCCHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRVISHPIQDISRAASLIAAGDLTATLPVQQRSDEIGLLVEMFTRMAEGLREQIRGLIEG
HHHHHHHHHHHHHHHHHHHCCCCEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ATVLGSAASDIVASTTQLSVSASESAVIVSETTVTVEEVRQTAQVASQKAKNVADSAQKA
HHHHCCHHHHHHHHHHEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQISQNGRKSTEDVAAGMNRIRLQMEAIAVSMTRLSEQSQAIGRIMATVEDLAAQSNLLA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VNAAIEAAKAGEHGKGFGVVAQEVKSLAEQSRQATNQVRTILGDIQKATTTAMMATEQGS
EHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KAVEAGTRQTEVASESIQALTASVNEATQAATQIAASSQQQLVGVDQVAGAMESIKQAST
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
QNVAGARQLEVAARNLNELGQRLKQMVERYKV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDWLANVPIRTKLLLISVLTSAIALLLAGAAIIVYDTITYTDQKKREISVQAETLAASVT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHCCCCCHHHHHHHHHHHHHHHHH
AALAFNDAKVAEEYLKAFEANPEIAAAGIYTTDARLFARYMRSGLSTRALPTAAEPAGER
HHHHCCHHHHHHHHHHHHCCCCCEEEECEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
FKDDELEVFRPIKDGARTVGTVYLRANTESLAIRIARFGGIILLVLVGSLVITLPISIRM
CCCCCHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRVISHPIQDISRAASLIAAGDLTATLPVQQRSDEIGLLVEMFTRMAEGLREQIRGLIEG
HHHHHHHHHHHHHHHHHHHCCCCEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ATVLGSAASDIVASTTQLSVSASESAVIVSETTVTVEEVRQTAQVASQKAKNVADSAQKA
HHHHCCHHHHHHHHHHEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQISQNGRKSTEDVAAGMNRIRLQMEAIAVSMTRLSEQSQAIGRIMATVEDLAAQSNLLA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VNAAIEAAKAGEHGKGFGVVAQEVKSLAEQSRQATNQVRTILGDIQKATTTAMMATEQGS
EHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KAVEAGTRQTEVASESIQALTASVNEATQAATQIAASSQQQLVGVDQVAGAMESIKQAST
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
QNVAGARQLEVAARNLNELGQRLKQMVERYKV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2492105; 1624419 [H]