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The map label for this gene is sir1 [H]

Identifier: 91788208

GI number: 91788208

Start: 2436142

End: 2437968

Strand: Reverse

Name: sir1 [H]

Synonym: Bpro_2339

Alternate gene names: 91788208

Gene position: 2437968-2436142 (Counterclockwise)

Preceding gene: 91788209

Following gene: 91788207

Centisome position: 46.88

GC content: 63.77

Gene sequence:

>1827_bases
ATGTACCAATACACAGAATTTGACCGCCAGTTCGTAAAAGCCCGCGCCAGCCAGTTCCGCGACCAGCTCACGCGCTGGCA
GGCCGGCCAGTTGCCCGAAGACGAATTTCGGCCGCTGCGCCTGCAAAACGGCTGGTATGTGCAGCGTTATGCCCCCATGC
TGCGCGTGGCCGTACCTTATGGCGAACTCTCCAGCGCCCAACTGCGTGTGTTGGCCAAAATTGCCCGCGAATACGACCAG
CCCAACGCCGCCCTGCTCGAAGGCGCGCAGGCCACCCAGGACAAGCTGGGCGCCATTCCGCTGAAAAACGGCCACTCGGT
GCATTCGAAACTGACCACGGGCTACGCCCACTTCACCACGCGCCAGAACGTCCAGTACAACTGGATTCCGCTGGACAAAT
CAGCCGACGTGATGGACCTGCTGGCCAGCGTCAACATGCACGGCATCCAGACCAGCGGCAACTGCATCCGCAACATCACC
AGCGACGAGCGTGCCGGCATTGCGGTCGATGAAATCGCCGACCCACGCCCGTTTGGCGAAATCATGCGCCAGTGGAGCAC
GCTGCACCCCGAGTTCTCCTTCTTGCCACGCAAGTTCAAGATCGCCATCAGCGGCGCCAGGGAAGACCGTGCCGCCATTG
GCTGGCACGACGTGGGCCTGCAACTGCTGCGCAACGCCGAGGGCGAGCTGGGCTTCAAGGTGCTGGTCGGTGGCGGCATG
GGTCGCACGCCCATCATCGGCACGGTGATCCGCGAGTTCCTGCCCTGGAACCAGATCATGAACTACCTGGAAGCCGTGGT
ACGCGTGTACAACCGCTATGGCCGCCGTGACAATATTTACAAGGCCCGCATCAAGATTCTGGTGAAGGCTGAAGGACAAC
GCTACATCGACGACGTCGAGGCCGAATACAAGCAGATCATGGAGCATGACGGTGGCCCGCACACCATCACACAGGCCGAA
TACGACCGCGTGGCCGCCTGCTTTGTGGCGCCCACCCTCAACTGCGACCGCAAGGAAGCCGACGCCAAGATCGCCCACAT
CCTGCGCGCTGCGGCCGAAGACGATGTCGAGTTTGGCCGCTGGCTGCAGCAAAACGTCGCACCGCACCAAAACCCGGACC
TGCGCGCCGTGACGCTGTCCTTCAAGCGCCTGGGCCAGGCCCCCGGCGATGCCACGGCGGCCCAGCTGGATGTCGCGGCC
GACCTGGCCGACCGTTTCAGCGCCGGTGAAATGCGCGTCACCCACGAGCAAAACCTGTTGCTGCCCTGGGTGCGCTGCGA
CGAGTTGCCCGAACTCTGGCGCGCCGCCCGCAAGGCCGGCTTTGCCAAACCCAACATCAAGCTGCTGACCGACATGATTG
CCTGCCCCGGCGGCGACTTCTGCTCGCTGGCCAACGCCCGTTCCATTCCGATTGCCGAAGCCATCACCGAGCGCTATCAG
GACCTGGACGAGCTGCACGACCTCGGCGAGATCGACCTGCACATCAGCGGCTGCATCAACTCCTGCGGCCACCACCACAG
CGGCCACATCGGCATTCTGGGTGTCGACAAGGACGGCAAGGAGTGGTACCAGGTGTCACTGGGCGGCTCGGACGGCTCCA
CGCTGTCTGGCCCTGCCGTGCCCGGCAAGGCCGTTGGCCCCTCTTTCTCGGCGGCTGAAGTCCCCGAAGTGATCGAAGCC
GTTCTGGAAACCTACCGCCAGCAGCGCGAAGGTGGCGAGACCTTTATTGCAACGTTGCGTCGCGTCGGTGCCGAACCCTT
CAAGGCTGCTGCGAATGGTGCGCGTTTTAGCGCCGCCCGCGCCGAGACGGCTGAAACGGCCGCCTGA

Upstream 100 bases:

>100_bases
TGAAGCTCATTTCGATATAGTCGGCTACTGTTTTTCCTTCCGTAGCTCACGCTGCTCCCCTGAACCGTTTCATCCTGAAC
CGTTTGATACCCCGACAGCC

Downstream 100 bases:

>100_bases
AGCGCCACCCTGCTGCACCTTCCAAGGACAAAATTACCATGAAACTAATAGCTGCTAGCGAGCCCTCCACTGGGGCTACA
GGCCAAAATGTCATTGAACT

Product: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 608; Mature: 608

Protein sequence:

>608_residues
MYQYTEFDRQFVKARASQFRDQLTRWQAGQLPEDEFRPLRLQNGWYVQRYAPMLRVAVPYGELSSAQLRVLAKIAREYDQ
PNAALLEGAQATQDKLGAIPLKNGHSVHSKLTTGYAHFTTRQNVQYNWIPLDKSADVMDLLASVNMHGIQTSGNCIRNIT
SDERAGIAVDEIADPRPFGEIMRQWSTLHPEFSFLPRKFKIAISGAREDRAAIGWHDVGLQLLRNAEGELGFKVLVGGGM
GRTPIIGTVIREFLPWNQIMNYLEAVVRVYNRYGRRDNIYKARIKILVKAEGQRYIDDVEAEYKQIMEHDGGPHTITQAE
YDRVAACFVAPTLNCDRKEADAKIAHILRAAAEDDVEFGRWLQQNVAPHQNPDLRAVTLSFKRLGQAPGDATAAQLDVAA
DLADRFSAGEMRVTHEQNLLLPWVRCDELPELWRAARKAGFAKPNIKLLTDMIACPGGDFCSLANARSIPIAEAITERYQ
DLDELHDLGEIDLHISGCINSCGHHHSGHIGILGVDKDGKEWYQVSLGGSDGSTLSGPAVPGKAVGPSFSAAEVPEVIEA
VLETYRQQREGGETFIATLRRVGAEPFKAAANGARFSAARAETAETAA

Sequences:

>Translated_608_residues
MYQYTEFDRQFVKARASQFRDQLTRWQAGQLPEDEFRPLRLQNGWYVQRYAPMLRVAVPYGELSSAQLRVLAKIAREYDQ
PNAALLEGAQATQDKLGAIPLKNGHSVHSKLTTGYAHFTTRQNVQYNWIPLDKSADVMDLLASVNMHGIQTSGNCIRNIT
SDERAGIAVDEIADPRPFGEIMRQWSTLHPEFSFLPRKFKIAISGAREDRAAIGWHDVGLQLLRNAEGELGFKVLVGGGM
GRTPIIGTVIREFLPWNQIMNYLEAVVRVYNRYGRRDNIYKARIKILVKAEGQRYIDDVEAEYKQIMEHDGGPHTITQAE
YDRVAACFVAPTLNCDRKEADAKIAHILRAAAEDDVEFGRWLQQNVAPHQNPDLRAVTLSFKRLGQAPGDATAAQLDVAA
DLADRFSAGEMRVTHEQNLLLPWVRCDELPELWRAARKAGFAKPNIKLLTDMIACPGGDFCSLANARSIPIAEAITERYQ
DLDELHDLGEIDLHISGCINSCGHHHSGHIGILGVDKDGKEWYQVSLGGSDGSTLSGPAVPGKAVGPSFSAAEVPEVIEA
VLETYRQQREGGETFIATLRRVGAEPFKAAANGARFSAARAETAETAA
>Mature_608_residues
MYQYTEFDRQFVKARASQFRDQLTRWQAGQLPEDEFRPLRLQNGWYVQRYAPMLRVAVPYGELSSAQLRVLAKIAREYDQ
PNAALLEGAQATQDKLGAIPLKNGHSVHSKLTTGYAHFTTRQNVQYNWIPLDKSADVMDLLASVNMHGIQTSGNCIRNIT
SDERAGIAVDEIADPRPFGEIMRQWSTLHPEFSFLPRKFKIAISGAREDRAAIGWHDVGLQLLRNAEGELGFKVLVGGGM
GRTPIIGTVIREFLPWNQIMNYLEAVVRVYNRYGRRDNIYKARIKILVKAEGQRYIDDVEAEYKQIMEHDGGPHTITQAE
YDRVAACFVAPTLNCDRKEADAKIAHILRAAAEDDVEFGRWLQQNVAPHQNPDLRAVTLSFKRLGQAPGDATAAQLDVAA
DLADRFSAGEMRVTHEQNLLLPWVRCDELPELWRAARKAGFAKPNIKLLTDMIACPGGDFCSLANARSIPIAEAITERYQ
DLDELHDLGEIDLHISGCINSCGHHHSGHIGILGVDKDGKEWYQVSLGGSDGSTLSGPAVPGKAVGPSFSAAEVPEVIEA
VLETYRQQREGGETFIATLRRVGAEPFKAAANGARFSAARAETAETAA

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

None

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 67412; Mature: 67412

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQYTEFDRQFVKARASQFRDQLTRWQAGQLPEDEFRPLRLQNGWYVQRYAPMLRVAVPY
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEEECCCEEHHHHCCCCEEECCC
GELSSAQLRVLAKIAREYDQPNAALLEGAQATQDKLGAIPLKNGHSVHSKLTTGYAHFTT
CCCCHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHCCHHEEEE
RQNVQYNWIPLDKSADVMDLLASVNMHGIQTSGNCIRNITSDERAGIAVDEIADPRPFGE
CCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCEEHHHCCCCCCHHH
IMRQWSTLHPEFSFLPRKFKIAISGAREDRAAIGWHDVGLQLLRNAEGELGFKVLVGGGM
HHHHHHHCCCCHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCC
GRTPIIGTVIREFLPWNQIMNYLEAVVRVYNRYGRRDNIYKARIKILVKAEGQRYIDDVE
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCHHHHHHH
AEYKQIMEHDGGPHTITQAEYDRVAACFVAPTLNCDRKEADAKIAHILRAAAEDDVEFGR
HHHHHHHHCCCCCCCCCHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
WLQQNVAPHQNPDLRAVTLSFKRLGQAPGDATAAQLDVAADLADRFSAGEMRVTHEQNLL
HHHHCCCCCCCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCE
LPWVRCDELPELWRAARKAGFAKPNIKLLTDMIACPGGDFCSLANARSIPIAEAITERYQ
ECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHH
DLDELHDLGEIDLHISGCINSCGHHHSGHIGILGVDKDGKEWYQVSLGGSDGSTLSGPAV
HHHHHHCCCCEEEEHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCC
PGKAVGPSFSAAEVPEVIEAVLETYRQQREGGETFIATLRRVGAEPFKAAANGARFSAAR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCCCHHHHHH
AETAETAA
HHHHHCCC
>Mature Secondary Structure
MYQYTEFDRQFVKARASQFRDQLTRWQAGQLPEDEFRPLRLQNGWYVQRYAPMLRVAVPY
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEEECCCEEHHHHCCCCEEECCC
GELSSAQLRVLAKIAREYDQPNAALLEGAQATQDKLGAIPLKNGHSVHSKLTTGYAHFTT
CCCCHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHCCHHEEEE
RQNVQYNWIPLDKSADVMDLLASVNMHGIQTSGNCIRNITSDERAGIAVDEIADPRPFGE
CCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCEEHHHCCCCCCHHH
IMRQWSTLHPEFSFLPRKFKIAISGAREDRAAIGWHDVGLQLLRNAEGELGFKVLVGGGM
HHHHHHHCCCCHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCC
GRTPIIGTVIREFLPWNQIMNYLEAVVRVYNRYGRRDNIYKARIKILVKAEGQRYIDDVE
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCHHHHHHH
AEYKQIMEHDGGPHTITQAEYDRVAACFVAPTLNCDRKEADAKIAHILRAAAEDDVEFGR
HHHHHHHHCCCCCCCCCHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
WLQQNVAPHQNPDLRAVTLSFKRLGQAPGDATAAQLDVAADLADRFSAGEMRVTHEQNLL
HHHHCCCCCCCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCE
LPWVRCDELPELWRAARKAGFAKPNIKLLTDMIACPGGDFCSLANARSIPIAEAITERYQ
ECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHH
DLDELHDLGEIDLHISGCINSCGHHHSGHIGILGVDKDGKEWYQVSLGGSDGSTLSGPAV
HHHHHHCCCCEEEEHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCC
PGKAVGPSFSAAEVPEVIEAVLETYRQQREGGETFIATLRRVGAEPFKAAANGARFSAAR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCCCHHHHHH
AETAETAA
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA