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The map label for this gene is aldH [H]

Identifier: 91788167

GI number: 91788167

Start: 2391136

End: 2392608

Strand: Reverse

Name: aldH [H]

Synonym: Bpro_2298

Alternate gene names: 91788167

Gene position: 2392608-2391136 (Counterclockwise)

Preceding gene: 91788168

Following gene: 91788166

Centisome position: 46.01

GC content: 69.65

Gene sequence:

>1473_bases
ATGAACACCCTGCAATCATTCAAAGCCCGCACCGGCGAAGCCTTCGGCGCCCCTCTTCCCGCCAGCACCCCGGAGCAGGT
CAACGCCGCGGCCGTTGCCGCCCAAGCCACCTTCGCCAGCTGGTCTGCCAGTACCGGCACCACCCGCGGAGCACTGCTGC
GCGCGCTGGCCGCAGCGCTGGAAGCTGACCGGGACGAACTGGTAGCCGTGGCAGACGAGGAGACTGCGCTGGGTCCGGTG
CGCCTGAACGGCGAACTCGACCGCACCGCCTTCCAGTTGCGCCGCTTTGCCGATATCGCCGAGCGCGGCGTGCCCTTTGC
CACCACGGATGATCCCGCCGTGGCCGGCCCCCCGCCCGCCGGTCACCCGGCCATGGTCCGCCTGCGCGTGCCGCTGGGCC
CTGTCGCCATGTTCTCGGCCAGCAATTTCCCGTTCGCGTTCTCGGTGCTGGGTGGCGACACCGCTTCGGCACTGGCTGCC
GGCTGCCCGGTGGTCGTCAAGGCCCACTCGGGCCACCTGGTGTTGTCAAACCGGGCATTTGGCCTGGTCCAGCAAGTCCT
CAAGGCCCAAAACCTGCCCGCAGGCCTGATCGGCATGATCCAGGGCGGCGGCTCCGATGTGGGCGTGCGTCTGGTGCGCC
ACCCGGCGATGGCCGCCGGCGCCTTCACCGGCTCGACGCGCGGCGGCGCGGCATTGCAGGCCGAGGCCAACGCGCGGCCA
CGCCCGATTCCGTTTTATGGCGAACTGGGGTCAACGAACCCCGTTGTCGCCCTGCCCGGCATTCTTGCTGCGCGCGGCGC
CGAGCTGGCCGGCGTGCTCGCCGGATCGATTTCCCTCGGATGCGGCCAGTTCTGTACCAGCCCCGGTGTGATCGTGCTGC
TCAAGGACCCTGCGAGCGACGCGTTTGTGCAGCAACTGACAAGCGCCCTGGCCACACAAAAACCCCATGCCATGCTGACC
CCGGGCATGCGCAGCGCCTTCGATGCCGGTGTAGCCCACATGGCCTCCGCCGGTGCGCAGCCCTTGCTGCAGGAAGCCGG
CAGCGCCGAGGCGCCCCGGCCCTTCCTGGCCCAGGTGGACGCCGTGAATTTCATCGCCAAGACCGAGTTGCGCGAAGAAG
TGTTCGGCCCCTCCAGCCTGATCGTGCGTGCCGATTCCATCGCGCAGGTGCTCGACGTGCTGCACGCCGTGGGTGGCAGC
CTGACGGTGACCCTCTGGGGTGCGGAAGACGACAATGCCGACACCCGCGCACTGGTGCGCGGCGCCACAGCCATTGCGGG
ACGCGTGCTGTTCGCCGGTGTGCCCACAGGTGTGGCCGTCACGGCCGCGCAGCAGCACGGCGGCCCATGGCCTTCGTCGA
CCCAGCCCATGACCACCTCGGTGGGTGACGCGGCGATGGAGCGCTTTCTGCGTCCCGTGGCCCTGCAGGACGCGCCAGCC
TGGCTGCTGGCACGCAAGGGACAGCCATGCTGA

Upstream 100 bases:

>100_bases
CTAACATACGACAAAGACAAGCACCAATGAAGCGCCCTGATGCCCTGTCCGTCCCGATCAGGATCCTCTCTTTCATTCGC
CCCCGAACCATTCAATTGCC

Downstream 100 bases:

>100_bases
ACCACCTCGTGATGTTCCGCCGTTCCGCCGCAAACGGGACGTTGAGGCCTGAACGACTATCTGTTCCACCCATTGCACCA
GGCCCTGATCGCCGACCTCA

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MNTLQSFKARTGEAFGAPLPASTPEQVNAAAVAAQATFASWSASTGTTRGALLRALAAALEADRDELVAVADEETALGPV
RLNGELDRTAFQLRRFADIAERGVPFATTDDPAVAGPPPAGHPAMVRLRVPLGPVAMFSASNFPFAFSVLGGDTASALAA
GCPVVVKAHSGHLVLSNRAFGLVQQVLKAQNLPAGLIGMIQGGGSDVGVRLVRHPAMAAGAFTGSTRGGAALQAEANARP
RPIPFYGELGSTNPVVALPGILAARGAELAGVLAGSISLGCGQFCTSPGVIVLLKDPASDAFVQQLTSALATQKPHAMLT
PGMRSAFDAGVAHMASAGAQPLLQEAGSAEAPRPFLAQVDAVNFIAKTELREEVFGPSSLIVRADSIAQVLDVLHAVGGS
LTVTLWGAEDDNADTRALVRGATAIAGRVLFAGVPTGVAVTAAQQHGGPWPSSTQPMTTSVGDAAMERFLRPVALQDAPA
WLLARKGQPC

Sequences:

>Translated_490_residues
MNTLQSFKARTGEAFGAPLPASTPEQVNAAAVAAQATFASWSASTGTTRGALLRALAAALEADRDELVAVADEETALGPV
RLNGELDRTAFQLRRFADIAERGVPFATTDDPAVAGPPPAGHPAMVRLRVPLGPVAMFSASNFPFAFSVLGGDTASALAA
GCPVVVKAHSGHLVLSNRAFGLVQQVLKAQNLPAGLIGMIQGGGSDVGVRLVRHPAMAAGAFTGSTRGGAALQAEANARP
RPIPFYGELGSTNPVVALPGILAARGAELAGVLAGSISLGCGQFCTSPGVIVLLKDPASDAFVQQLTSALATQKPHAMLT
PGMRSAFDAGVAHMASAGAQPLLQEAGSAEAPRPFLAQVDAVNFIAKTELREEVFGPSSLIVRADSIAQVLDVLHAVGGS
LTVTLWGAEDDNADTRALVRGATAIAGRVLFAGVPTGVAVTAAQQHGGPWPSSTQPMTTSVGDAAMERFLRPVALQDAPA
WLLARKGQPC
>Mature_490_residues
MNTLQSFKARTGEAFGAPLPASTPEQVNAAAVAAQATFASWSASTGTTRGALLRALAAALEADRDELVAVADEETALGPV
RLNGELDRTAFQLRRFADIAERGVPFATTDDPAVAGPPPAGHPAMVRLRVPLGPVAMFSASNFPFAFSVLGGDTASALAA
GCPVVVKAHSGHLVLSNRAFGLVQQVLKAQNLPAGLIGMIQGGGSDVGVRLVRHPAMAAGAFTGSTRGGAALQAEANARP
RPIPFYGELGSTNPVVALPGILAARGAELAGVLAGSISLGCGQFCTSPGVIVLLKDPASDAFVQQLTSALATQKPHAMLT
PGMRSAFDAGVAHMASAGAQPLLQEAGSAEAPRPFLAQVDAVNFIAKTELREEVFGPSSLIVRADSIAQVLDVLHAVGGS
LTVTLWGAEDDNADTRALVRGATAIAGRVLFAGVPTGVAVTAAQQHGGPWPSSTQPMTTSVGDAAMERFLRPVALQDAPA
WLLARKGQPC

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=367, Percent_Identity=24.7956403269755, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1787558, Length=400, Percent_Identity=27.5, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081896, Length=416, Percent_Identity=25.9615384615385, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787250, Length=472, Percent_Identity=25.635593220339, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789015, Length=304, Percent_Identity=25.9868421052632, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17551164, Length=418, Percent_Identity=22.7272727272727, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI133930964, Length=401, Percent_Identity=25.9351620947631, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71995613, Length=327, Percent_Identity=27.217125382263, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71995606, Length=326, Percent_Identity=27.3006134969325, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323821, Length=309, Percent_Identity=28.1553398058252, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323822, Length=312, Percent_Identity=27.2435897435897, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24666674, Length=306, Percent_Identity=26.1437908496732, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 49922; Mature: 49922

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLQSFKARTGEAFGAPLPASTPEQVNAAAVAAQATFASWSASTGTTRGALLRALAAAL
CCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
EADRDELVAVADEETALGPVRLNGELDRTAFQLRRFADIAERGVPFATTDDPAVAGPPPA
HCCCCCEEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GHPAMVRLRVPLGPVAMFSASNFPFAFSVLGGDTASALAAGCPVVVKAHSGHLVLSNRAF
CCCEEEEEECCCCCEEEEECCCCCEEEEEECCCHHHHHHCCCCEEEEECCCEEEECCCHH
GLVQQVLKAQNLPAGLIGMIQGGGSDVGVRLVRHPAMAAGAFTGSTRGGAALQAEANARP
HHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHCCCHHHCCCCCCCCCCEEEEECCCCCC
RPIPFYGELGSTNPVVALPGILAARGAELAGVLAGSISLGCGQFCTSPGVIVLLKDPASD
CCCCCCCCCCCCCCEEECCCHHHHCCCHHHHHHHCCHHCCCHHHCCCCCEEEEEECCCCH
AFVQQLTSALATQKPHAMLTPGMRSAFDAGVAHMASAGAQPLLQEAGSAEAPRPFLAQVD
HHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHH
AVNFIAKTELREEVFGPSSLIVRADSIAQVLDVLHAVGGSLTVTLWGAEDDNADTRALVR
HHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHH
GATAIAGRVLFAGVPTGVAVTAAQQHGGPWPSSTQPMTTSVGDAAMERFLRPVALQDAPA
HHHHHHCEEEEECCCCCEEEEEHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCH
WLLARKGQPC
HEEECCCCCC
>Mature Secondary Structure
MNTLQSFKARTGEAFGAPLPASTPEQVNAAAVAAQATFASWSASTGTTRGALLRALAAAL
CCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
EADRDELVAVADEETALGPVRLNGELDRTAFQLRRFADIAERGVPFATTDDPAVAGPPPA
HCCCCCEEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GHPAMVRLRVPLGPVAMFSASNFPFAFSVLGGDTASALAAGCPVVVKAHSGHLVLSNRAF
CCCEEEEEECCCCCEEEEECCCCCEEEEEECCCHHHHHHCCCCEEEEECCCEEEECCCHH
GLVQQVLKAQNLPAGLIGMIQGGGSDVGVRLVRHPAMAAGAFTGSTRGGAALQAEANARP
HHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHCCCHHHCCCCCCCCCCEEEEECCCCCC
RPIPFYGELGSTNPVVALPGILAARGAELAGVLAGSISLGCGQFCTSPGVIVLLKDPASD
CCCCCCCCCCCCCCEEECCCHHHHCCCHHHHHHHCCHHCCCHHHCCCCCEEEEEECCCCH
AFVQQLTSALATQKPHAMLTPGMRSAFDAGVAHMASAGAQPLLQEAGSAEAPRPFLAQVD
HHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHH
AVNFIAKTELREEVFGPSSLIVRADSIAQVLDVLHAVGGSLTVTLWGAEDDNADTRALVR
HHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHH
GATAIAGRVLFAGVPTGVAVTAAQQHGGPWPSSTQPMTTSVGDAAMERFLRPVALQDAPA
HHHHHHCEEEEECCCCCEEEEEHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCH
WLLARKGQPC
HEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]