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The map label for this gene is hppA [H]

Identifier: 91788168

GI number: 91788168

Start: 2393037

End: 2395235

Strand: Reverse

Name: hppA [H]

Synonym: Bpro_2299

Alternate gene names: 91788168

Gene position: 2395235-2393037 (Counterclockwise)

Preceding gene: 91788170

Following gene: 91788167

Centisome position: 46.06

GC content: 65.26

Gene sequence:

>2199_bases
ATGACAGGCAACTCAGCGCTCATTCTTGCGCTCGTCTGCGGGCTTATTGCCGTGGGGTACGGCTTCTGGGCACGCAGCTG
GATTCTTTCCCAGGACGCCGGCAATGCACGCATGCAGGAAATCGCGGCCGCCATACAAACCGGTGCGGCGGCTTATCTGG
CCCGGCAGTACAAAACCATCGCCATTGTGGGCGTGGTCCTGGCCCTGCTGATCGGCTTTTTCCTGGACGGCAAAACCGCC
ATCGGCTTCTGTGTAGGTGCCGTGCTGTCAGGGGCCTGCGGCTTCATCGGCATGAATGTATCGGTGCGCGCCAATGTACG
CACCGCACAGGCCGCCACCCGCGGCATTGGCCCCGCACTGGATGTCGCCTTCCGCGGCGGCGCCATCACCGGCATGCTGG
TGGTCGGTCTCGGCCTGCTGGGTGTGACCTCGTTTTACTGGTTTCTGGTGGGCAACGGCAACTACACGCCCGACCGCAAG
CTGGCCGAATTGCTCAACCCGCTGATCGGCCTAGCCTTCGGCGCTTCGCTGATCTCGATCTTCGCCCGTCTGGGCGGCGG
CATTTTCACCAAGGGCGCTGACGTCGGCGCCGACCTGGTGGGCAAGGTCGAAGCCGGCATACCCGAAGATGATCCGCGCA
ACCCGGCCGTGATCGCCGACAACGTGGGCGACAACGTGGGCGACTGCGCCGGCATGGCGGCCGACCTGTTTGAAACCTAC
GCGGTGACGCTGATTGCCACCATGGTGCTGGGCGCCCTGCTGGTGGCGGCTGCCCCGCTCAACGCTGTGGTCTACCCGCT
GGCACTCGGTGCCGTGTCCATCGTGGCGTCCATCATCGGCTGCTTCTTCGTCAAGGCTTCGCCCGTCATGAAGAACGTGA
TGCCGGCGCTGTACAGGGGCCTGGCCGTGGCCGGCGTGCTGTCGCTGATCGCCTTCTACTTCGTCACGATGTGGCTGATG
CCTGACAACGCGATTGCCGCCTCAGGCACGCAGATACGCCTGTTCGGCGCCTGCGCCGTCGGCCTGATACTGACCGGTGC
GCTGGTCTGGATCACCGAGTTCTACACCGGCACGCAGTACTCGCCGGTGCAGCACATCGCGCAAGCTTCCACCACCGGTC
ATGGCACCAACATCATTGCGGGTCTGGGCGTGTCCATGCGTTCCACCGCGTGGCCGGTGCTCTGCGTCTGTATCGCCATC
ATGACGGCCTATTCGCTGGCCGGCCTGTACGGCATTGCCACCGCAGCCACCGCCATGCTGAGCATGGCCGGCATTGTGGT
GGCGCTGGACGCCTACGGTCCGATCACCGACAACGCCGGCGGCATTGCCGAAATGTCCAAATTGCCCGCCAGCGTACGGG
AGATCACCGACCCGCTGGACGCGGTGGGCAACACCACCAAGGCCGTGACCAAAGGCTACGCCATCGGCTCGGCCGGCCTG
GCCGCGCTGGTGCTGTTTGCCGACTACACCCACAAGCTGGAAGGCTATGGCAACGCCATCAGCTTTGATCTGAGCGACCC
GATGGTGATCGTGGGTCTGTTCATCGGCGGCCTGATCCCCTACCTGTTTGGCGCCATGGCGATGGAGGCCGTGGGCCGCG
CCGCCGGCTCGGTGGTGGTGGAAGTGCGCCGCCAGTTCCGCGAGATCAAGGGCATCATGGAAGGCACGGCCAAGCCCGAG
TACGGCAAGGCCGTCGATATGCTGACCACCGCGGCGATCAAGGAAATGGTGATCCCGTCGCTGCTGCCGGTGGTGGTGCC
GATCGTGGTCGGCCTCGTGCTGGGCCCCAAGGCGCTGGGCGGCATGCTGATGGGCACCATCGTGACCGGCCTGTTCGTGG
CGATCTCGATGTGCACCGGTGGCGGTGCCTGGGACAACGCCAAGAAATACATTGAAGACGGCAACCATGGCGGCAAAGGC
TCGGAAGCGCACAAGGCCGCCGTGACCGGCGACACCGTGGGCGACCCCTACAAGGACACCGCCGGTCCGGCCGTGAACCC
GCTGATCAAGATCATCAACATCGTGGCGCTGCTGATCGTGCCCTTGATGATGAAGTTCCATGGCGGCCCGGCCAGCGCAG
CGCCGGTCATGCCGATGGCGGCGCCCGCAGCCGTGTCGGCCCCCGCTCCGGCGATGCCTGCGCCAGCAGTGGCAACACCC
ATGGCGCCCGCAGCACCCGCGGCATCAGCATCCAAATAA

Upstream 100 bases:

>100_bases
GTCTCCAAGCATGTTGGAAGCAGCGAGGAAGCAACGCAGCGGGGGTTTCACACCACACTAGCGTTGCTACCCCCTCCAAG
CGAAAAACAAGGAGATCTCT

Downstream 100 bases:

>100_bases
AGACAATAAAGACGCTTGCTCGTTCAAAGCCCGCCTCGGCGGGCTTTTTTATTGGCCGTCGACAAGCCCGATCCATTGAG
AGCATTCTTCGAAGGACGTG

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound proton-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; H(+)-PPase [H]

Number of amino acids: Translated: 732; Mature: 731

Protein sequence:

>732_residues
MTGNSALILALVCGLIAVGYGFWARSWILSQDAGNARMQEIAAAIQTGAAAYLARQYKTIAIVGVVLALLIGFFLDGKTA
IGFCVGAVLSGACGFIGMNVSVRANVRTAQAATRGIGPALDVAFRGGAITGMLVVGLGLLGVTSFYWFLVGNGNYTPDRK
LAELLNPLIGLAFGASLISIFARLGGGIFTKGADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAADLFETY
AVTLIATMVLGALLVAAAPLNAVVYPLALGAVSIVASIIGCFFVKASPVMKNVMPALYRGLAVAGVLSLIAFYFVTMWLM
PDNAIAASGTQIRLFGACAVGLILTGALVWITEFYTGTQYSPVQHIAQASTTGHGTNIIAGLGVSMRSTAWPVLCVCIAI
MTAYSLAGLYGIATAATAMLSMAGIVVALDAYGPITDNAGGIAEMSKLPASVREITDPLDAVGNTTKAVTKGYAIGSAGL
AALVLFADYTHKLEGYGNAISFDLSDPMVIVGLFIGGLIPYLFGAMAMEAVGRAAGSVVVEVRRQFREIKGIMEGTAKPE
YGKAVDMLTTAAIKEMVIPSLLPVVVPIVVGLVLGPKALGGMLMGTIVTGLFVAISMCTGGGAWDNAKKYIEDGNHGGKG
SEAHKAAVTGDTVGDPYKDTAGPAVNPLIKIINIVALLIVPLMMKFHGGPASAAPVMPMAAPAAVSAPAPAMPAPAVATP
MAPAAPAASASK

Sequences:

>Translated_732_residues
MTGNSALILALVCGLIAVGYGFWARSWILSQDAGNARMQEIAAAIQTGAAAYLARQYKTIAIVGVVLALLIGFFLDGKTA
IGFCVGAVLSGACGFIGMNVSVRANVRTAQAATRGIGPALDVAFRGGAITGMLVVGLGLLGVTSFYWFLVGNGNYTPDRK
LAELLNPLIGLAFGASLISIFARLGGGIFTKGADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAADLFETY
AVTLIATMVLGALLVAAAPLNAVVYPLALGAVSIVASIIGCFFVKASPVMKNVMPALYRGLAVAGVLSLIAFYFVTMWLM
PDNAIAASGTQIRLFGACAVGLILTGALVWITEFYTGTQYSPVQHIAQASTTGHGTNIIAGLGVSMRSTAWPVLCVCIAI
MTAYSLAGLYGIATAATAMLSMAGIVVALDAYGPITDNAGGIAEMSKLPASVREITDPLDAVGNTTKAVTKGYAIGSAGL
AALVLFADYTHKLEGYGNAISFDLSDPMVIVGLFIGGLIPYLFGAMAMEAVGRAAGSVVVEVRRQFREIKGIMEGTAKPE
YGKAVDMLTTAAIKEMVIPSLLPVVVPIVVGLVLGPKALGGMLMGTIVTGLFVAISMCTGGGAWDNAKKYIEDGNHGGKG
SEAHKAAVTGDTVGDPYKDTAGPAVNPLIKIINIVALLIVPLMMKFHGGPASAAPVMPMAAPAAVSAPAPAMPAPAVATP
MAPAAPAASASK
>Mature_731_residues
TGNSALILALVCGLIAVGYGFWARSWILSQDAGNARMQEIAAAIQTGAAAYLARQYKTIAIVGVVLALLIGFFLDGKTAI
GFCVGAVLSGACGFIGMNVSVRANVRTAQAATRGIGPALDVAFRGGAITGMLVVGLGLLGVTSFYWFLVGNGNYTPDRKL
AELLNPLIGLAFGASLISIFARLGGGIFTKGADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAADLFETYA
VTLIATMVLGALLVAAAPLNAVVYPLALGAVSIVASIIGCFFVKASPVMKNVMPALYRGLAVAGVLSLIAFYFVTMWLMP
DNAIAASGTQIRLFGACAVGLILTGALVWITEFYTGTQYSPVQHIAQASTTGHGTNIIAGLGVSMRSTAWPVLCVCIAIM
TAYSLAGLYGIATAATAMLSMAGIVVALDAYGPITDNAGGIAEMSKLPASVREITDPLDAVGNTTKAVTKGYAIGSAGLA
ALVLFADYTHKLEGYGNAISFDLSDPMVIVGLFIGGLIPYLFGAMAMEAVGRAAGSVVVEVRRQFREIKGIMEGTAKPEY
GKAVDMLTTAAIKEMVIPSLLPVVVPIVVGLVLGPKALGGMLMGTIVTGLFVAISMCTGGGAWDNAKKYIEDGNHGGKGS
EAHKAAVTGDTVGDPYKDTAGPAVNPLIKIINIVALLIVPLMMKFHGGPASAAPVMPMAAPAAVSAPAPAMPAPAVATPM
APAAPAASASK

Specific function: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 74453; Mature: 74321

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGNSALILALVCGLIAVGYGFWARSWILSQDAGNARMQEIAAAIQTGAAAYLARQYKTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AIVGVVLALLIGFFLDGKTAIGFCVGAVLSGACGFIGMNVSVRANVRTAQAATRGIGPAL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHEECCEEEEECCHHHHHHHHCCCHHH
DVAFRGGAITGMLVVGLGLLGVTSFYWFLVGNGNYTPDRKLAELLNPLIGLAFGASLISI
HHHCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FARLGGGIFTKGADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAADLFETY
HHHHCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
AVTLIATMVLGALLVAAAPLNAVVYPLALGAVSIVASIIGCFFVKASPVMKNVMPALYRG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LAVAGVLSLIAFYFVTMWLMPDNAIAASGTQIRLFGACAVGLILTGALVWITEFYTGTQY
HHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCC
SPVQHIAQASTTGHGTNIIAGLGVSMRSTAWPVLCVCIAIMTAYSLAGLYGIATAATAML
CHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMAGIVVALDAYGPITDNAGGIAEMSKLPASVREITDPLDAVGNTTKAVTKGYAIGSAGL
HHHHHHEEEECCCCCCCCCCCHHHHHHCCHHHHHHHCHHHHHCCCHHHHHHCCCCCHHHH
AALVLFADYTHKLEGYGNAISFDLSDPMVIVGLFIGGLIPYLFGAMAMEAVGRAAGSVVV
HHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVRRQFREIKGIMEGTAKPEYGKAVDMLTTAAIKEMVIPSLLPVVVPIVVGLVLGPKALG
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
GMLMGTIVTGLFVAISMCTGGGAWDNAKKYIEDGNHGGKGSEAHKAAVTGDTVGDPYKDT
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHEECCCCCCCCCCCC
AGPAVNPLIKIINIVALLIVPLMMKFHGGPASAAPVMPMAAPAAVSAPAPAMPAPAVATP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MAPAAPAASASK
CCCCCCCCCCCC
>Mature Secondary Structure 
TGNSALILALVCGLIAVGYGFWARSWILSQDAGNARMQEIAAAIQTGAAAYLARQYKTI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AIVGVVLALLIGFFLDGKTAIGFCVGAVLSGACGFIGMNVSVRANVRTAQAATRGIGPAL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHEECCEEEEECCHHHHHHHHCCCHHH
DVAFRGGAITGMLVVGLGLLGVTSFYWFLVGNGNYTPDRKLAELLNPLIGLAFGASLISI
HHHCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FARLGGGIFTKGADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAADLFETY
HHHHCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
AVTLIATMVLGALLVAAAPLNAVVYPLALGAVSIVASIIGCFFVKASPVMKNVMPALYRG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LAVAGVLSLIAFYFVTMWLMPDNAIAASGTQIRLFGACAVGLILTGALVWITEFYTGTQY
HHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCC
SPVQHIAQASTTGHGTNIIAGLGVSMRSTAWPVLCVCIAIMTAYSLAGLYGIATAATAML
CHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMAGIVVALDAYGPITDNAGGIAEMSKLPASVREITDPLDAVGNTTKAVTKGYAIGSAGL
HHHHHHEEEECCCCCCCCCCCHHHHHHCCHHHHHHHCHHHHHCCCHHHHHHCCCCCHHHH
AALVLFADYTHKLEGYGNAISFDLSDPMVIVGLFIGGLIPYLFGAMAMEAVGRAAGSVVV
HHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVRRQFREIKGIMEGTAKPEYGKAVDMLTTAAIKEMVIPSLLPVVVPIVVGLVLGPKALG
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
GMLMGTIVTGLFVAISMCTGGGAWDNAKKYIEDGNHGGKGSEAHKAAVTGDTVGDPYKDT
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHEECCCCCCCCCCCC
AGPAVNPLIKIINIVALLIVPLMMKFHGGPASAAPVMPMAAPAAVSAPAPAMPAPAVATP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MAPAAPAASASK
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA