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The map label for this gene is hutH [H]

Identifier: 91786942

GI number: 91786942

Start: 1069620

End: 1071164

Strand: Reverse

Name: hutH [H]

Synonym: Bpro_1043

Alternate gene names: 91786942

Gene position: 1071164-1069620 (Counterclockwise)

Preceding gene: 91786943

Following gene: 91786941

Centisome position: 20.6

GC content: 70.36

Gene sequence:

>1545_bases
ATGACAACATCCACCCACATCCTGCACCCCGGCCGCGTCAGCCTGGCCCTGTTGCGCAGCATCCATGCCGGCGGCGTGCA
GCTGGCCCTGGCGCCCGAGGCCCGTGCCGGCCTGCTGGCAGCCCAGGCCACCGTGCAGCGCATCGTCGATGAAGACCAGG
TCGTCTACGGCATCAACACCGGCTTCGGCAAACTGGCCAGCACCAAGATTGCGCCCAACCGCCTGGTCGAATTACAGCGC
AACCTGGTGCTGTCGCACAGCGTGGGCACCGGCGAGCCGCTACCGGCCGCCGTGGTGCGCGTGATCCTCGCTACCAAGGC
GGTGAGCCTGGCGCGCGGCCACTCCGGCGTGCGGCCCGAACTGGTGGACGCCTTGCTGGCGCTGGCCAACGCGGGCGTGA
TGCCGCGCATCCCGGCCAAGGGCTCCGTGGGTGCCTCCGGCGACCTGGCGCCTCTGGCGCACCTGGCCTGCGTGCTGATC
GGCGAAGGCCAGGCCACCACCGCCGACGGCGAAGTCATTTCCGGCGCCCAGGCCATGCGCCGCATCGGCGTGGCGCCGTT
TGTGCTCGGCCCCAAGGAAGGCCTGGCGCTGCTCAACGGCACCCAGGTGTCTACCGCCCTGGCGCTGGCCGGCCTGTTCG
GCGCCGAACAGGTATTTGCCGCGGGCCTGGTGTCCGGCGCCTTGTCGCTGGAAGCCGTGCAGGGCTCCATCAAGCCGTTT
GACGCGCGGGTGCATGCCGCGCGTGGCCAGCCCGGCCAGATGGCCGTGGCGGCGGCGGTGCGCACCCTGCTCGAAGGCAG
CGAGATCGTGCCGTCGCACCCCGACTGCGGCCGCGTGCAGGACCCGTATTCGATCCGCTGCGTGCCCCAAGTCATGGGCG
CCTGCCTGGACAACCTGCAGCACGCCGCCCGGGTGCTGCAGATCGAGGCCAATGCCGCCTCCGACAACCCGCTGGTCTTC
GACAACGGCGACGTGATCTCCGGCGGCAACTTCCACGCCGAGCCGGTGGCCTTTGCGGCCGACATCATCGCGCTGGCCGT
GGCCGAGATCGGCGCGATTGCCGAGCGCCGCCTGGCACTGCTGCTCGACACCGGCCTCTCCGGCCTGCCGCCTTTCCTGG
TGCGCGATGGCGGCGTCAACTCCGGCTTCATGATTGCCCAGGTCACCGCCGCCGCGCTGGCCTCGGAAAACAAATCCCTG
GCGCACCCGGCCAGCGTGGACAGCCTGCCCACCTCGGCCAACCAGGAGGACCATGTGTCGATGGCGACCTTCGCCGCGCG
CCGCCTGGGCGAGATGGTGAACAACACCGCCGTCGTCGTCGGCATCGAAGCCATGGGCGCTGCTCAAGGCATAGAACTCA
AGCGCGGGCTCAAAAGCTCCCCGCTGATCGAAGCCGAGTTCGCCCGCATCCGCGGGAAGGTGGCCTTCCTCGACCAGGAC
CGCTTCCTCGCGACCGACGTCGAAGCCATGCGCCAGTGGGCCTTGCACAGCGACTGGCCCGCCGCCCTGCAGCAGATCCT
GCCCAGCCACGCCACCGCGGCCTGA

Upstream 100 bases:

>100_bases
CGACGGGCCACCCCGGCGAGCCAGCCAGCCAGCAAGTAAACAAACGAATAAAAACTTCTTTATCATCGATTCCGACAACT
TGTATATACAGGACTAGACA

Downstream 100 bases:

>100_bases
CGCCGGGCCTGAACCTCAGCCTGAAACCCATTCCAACCGTTTTATCCAGGAGACCGCCATGAACGCCAAGGATTCCTTCA
TCGCCCCCACCGACGCCCAA

Product: histidine ammonia-lyase

Products: NA

Alternate protein names: Histidase [H]

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MTTSTHILHPGRVSLALLRSIHAGGVQLALAPEARAGLLAAQATVQRIVDEDQVVYGINTGFGKLASTKIAPNRLVELQR
NLVLSHSVGTGEPLPAAVVRVILATKAVSLARGHSGVRPELVDALLALANAGVMPRIPAKGSVGASGDLAPLAHLACVLI
GEGQATTADGEVISGAQAMRRIGVAPFVLGPKEGLALLNGTQVSTALALAGLFGAEQVFAAGLVSGALSLEAVQGSIKPF
DARVHAARGQPGQMAVAAAVRTLLEGSEIVPSHPDCGRVQDPYSIRCVPQVMGACLDNLQHAARVLQIEANAASDNPLVF
DNGDVISGGNFHAEPVAFAADIIALAVAEIGAIAERRLALLLDTGLSGLPPFLVRDGGVNSGFMIAQVTAAALASENKSL
AHPASVDSLPTSANQEDHVSMATFAARRLGEMVNNTAVVVGIEAMGAAQGIELKRGLKSSPLIEAEFARIRGKVAFLDQD
RFLATDVEAMRQWALHSDWPAALQQILPSHATAA

Sequences:

>Translated_514_residues
MTTSTHILHPGRVSLALLRSIHAGGVQLALAPEARAGLLAAQATVQRIVDEDQVVYGINTGFGKLASTKIAPNRLVELQR
NLVLSHSVGTGEPLPAAVVRVILATKAVSLARGHSGVRPELVDALLALANAGVMPRIPAKGSVGASGDLAPLAHLACVLI
GEGQATTADGEVISGAQAMRRIGVAPFVLGPKEGLALLNGTQVSTALALAGLFGAEQVFAAGLVSGALSLEAVQGSIKPF
DARVHAARGQPGQMAVAAAVRTLLEGSEIVPSHPDCGRVQDPYSIRCVPQVMGACLDNLQHAARVLQIEANAASDNPLVF
DNGDVISGGNFHAEPVAFAADIIALAVAEIGAIAERRLALLLDTGLSGLPPFLVRDGGVNSGFMIAQVTAAALASENKSL
AHPASVDSLPTSANQEDHVSMATFAARRLGEMVNNTAVVVGIEAMGAAQGIELKRGLKSSPLIEAEFARIRGKVAFLDQD
RFLATDVEAMRQWALHSDWPAALQQILPSHATAA
>Mature_513_residues
TTSTHILHPGRVSLALLRSIHAGGVQLALAPEARAGLLAAQATVQRIVDEDQVVYGINTGFGKLASTKIAPNRLVELQRN
LVLSHSVGTGEPLPAAVVRVILATKAVSLARGHSGVRPELVDALLALANAGVMPRIPAKGSVGASGDLAPLAHLACVLIG
EGQATTADGEVISGAQAMRRIGVAPFVLGPKEGLALLNGTQVSTALALAGLFGAEQVFAAGLVSGALSLEAVQGSIKPFD
ARVHAARGQPGQMAVAAAVRTLLEGSEIVPSHPDCGRVQDPYSIRCVPQVMGACLDNLQHAARVLQIEANAASDNPLVFD
NGDVISGGNFHAEPVAFAADIIALAVAEIGAIAERRLALLLDTGLSGLPPFLVRDGGVNSGFMIAQVTAAALASENKSLA
HPASVDSLPTSANQEDHVSMATFAARRLGEMVNNTAVVVGIEAMGAAQGIELKRGLKSSPLIEAEFARIRGKVAFLDQDR
FLATDVEAMRQWALHSDWPAALQQILPSHATAA

Specific function: Unknown

COG id: COG2986

COG function: function code E; Histidine ammonia-lyase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAL/histidase family [H]

Homologues:

Organism=Homo sapiens, GI4504333, Length=497, Percent_Identity=43.8631790744467, Blast_Score=400, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17567831, Length=487, Percent_Identity=41.8891170431211, Blast_Score=356, Evalue=1e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005921
- InterPro:   IPR008948
- InterPro:   IPR001106
- InterPro:   IPR022313 [H]

Pfam domain/function: PF00221 PAL [H]

EC number: =4.3.1.3 [H]

Molecular weight: Translated: 52956; Mature: 52824

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00488 PAL_HISTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSTHILHPGRVSLALLRSIHAGGVQLALAPEARAGLLAAQATVQRIVDEDQVVYGINT
CCCCCEEECCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECC
GFGKLASTKIAPNRLVELQRNLVLSHSVGTGEPLPAAVVRVILATKAVSLARGHSGVRPE
CCCHHHCCCCCHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
LVDALLALANAGVMPRIPAKGSVGASGDLAPLAHLACVLIGEGQATTADGEVISGAQAMR
HHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHH
RIGVAPFVLGPKEGLALLNGTQVSTALALAGLFGAEQVFAAGLVSGALSLEAVQGSIKPF
HHCCCCEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DARVHAARGQPGQMAVAAAVRTLLEGSEIVPSHPDCGRVQDPYSIRCVPQVMGACLDNLQ
CCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHH
HAARVLQIEANAASDNPLVFDNGDVISGGNFHAEPVAFAADIIALAVAEIGAIAERRLAL
HHHHEEEEEECCCCCCCEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLDTGLSGLPPFLVRDGGVNSGFMIAQVTAAALASENKSLAHPASVDSLPTSANQEDHVS
HHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHH
MATFAARRLGEMVNNTAVVVGIEAMGAAQGIELKRGLKSSPLIEAEFARIRGKVAFLDQD
HHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCHHHCCCCCCCCHHHHHHHHCCEEEEEECC
RFLATDVEAMRQWALHSDWPAALQQILPSHATAA
CHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTSTHILHPGRVSLALLRSIHAGGVQLALAPEARAGLLAAQATVQRIVDEDQVVYGINT
CCCCEEECCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECC
GFGKLASTKIAPNRLVELQRNLVLSHSVGTGEPLPAAVVRVILATKAVSLARGHSGVRPE
CCCHHHCCCCCHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
LVDALLALANAGVMPRIPAKGSVGASGDLAPLAHLACVLIGEGQATTADGEVISGAQAMR
HHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHH
RIGVAPFVLGPKEGLALLNGTQVSTALALAGLFGAEQVFAAGLVSGALSLEAVQGSIKPF
HHCCCCEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DARVHAARGQPGQMAVAAAVRTLLEGSEIVPSHPDCGRVQDPYSIRCVPQVMGACLDNLQ
CCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHH
HAARVLQIEANAASDNPLVFDNGDVISGGNFHAEPVAFAADIIALAVAEIGAIAERRLAL
HHHHEEEEEECCCCCCCEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLDTGLSGLPPFLVRDGGVNSGFMIAQVTAAALASENKSLAHPASVDSLPTSANQEDHVS
HHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHH
MATFAARRLGEMVNNTAVVVGIEAMGAAQGIELKRGLKSSPLIEAEFARIRGKVAFLDQD
HHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCHHHCCCCCCCCHHHHHHHHCCEEEEEECC
RFLATDVEAMRQWALHSDWPAALQQILPSHATAA
CHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA