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The map label for this gene is hutU [H]

Identifier: 91786941

GI number: 91786941

Start: 1067822

End: 1069561

Strand: Reverse

Name: hutU [H]

Synonym: Bpro_1042

Alternate gene names: 91786941

Gene position: 1069561-1067822 (Counterclockwise)

Preceding gene: 91786942

Following gene: 91786940

Centisome position: 20.57

GC content: 66.32

Gene sequence:

>1740_bases
ATGAACGCCAAGGATTCCTTCATCGCCCCCACCGACGCCCAAAGCGGCACCCTCACCGACCCGCGCGTCGACCCCACCCG
TGTGATCCGCGCGCCGCGCGGCAGCCAGCTCCATTGCAAAAGCTGGCTCACCGAAGCCGCCTTTCGCATGATCCAGAACA
ACCTCGACCCCGAGGTGGCCGAGAACCCGCAAAGCCTGGTGGTCTACGGCGGCATCGGCCGCGCCGCACGCGACTGGGCC
TGCTTCGACCAGATTCTGGCTTCGCTGAAAGAACTAAACGATGACGAATCGCTGTTGGTCCAGTCAGGCAAGCCCGTGGG
CGTATTCAAGACCCACGCCAACGCGCCTCGCGTGCTGATCGCCAACTCCAACCTGGTGCCCAAGTGGGCCAACTGGGAAC
ACTTCAACGAACTCGACCGCAAGGGCCTCTTCATGTATGGCCAGATGACGGCCGGCAGCTGGATCTACATCGGCAGCCAG
GGCATCGTGCAGGGCACCTTCGAGACCTTCGTCGAAGCCGGCCGCCAACACTACAACAACAGCCTCGCTGGCAAATGGAT
CCTGACCGCGGGCCTGGGCGGCATGGGGGGCGCGCAGCCGCTGGCAGCAACCTTGGCCGGCGCGGTGTCGCTGAACATCG
AGTGCCAGCAAAGCAGCATCGACTTCCGCCTGCGCACCCGCTACGTGGACAAGCAGGCCAGGGACATCGACGACGCGCTG
GCGCTGATCAAGTACCACACCGACCGCAAGGAGGCCGTGTCGATCGCGCTGCTGGGCAACGCCGCCGACATCCTGCCCGA
GCTGGTGAAGCGCGCCAAAGCCGGCGCCATCAAGCCCGACCTGGTGACCGACCAGACCTCGGCCCACGACCTGATCAACG
GCTACCTGCCCCGCGGCTGGAACGTGGCGCAGTGGAAGGCCGCGCAGCAGGATCCGGCGCAGCACAAGCGCCTGACGGAC
GAAGCCGCCCAAAGCTGCGCCGTGCATGTGCAGGCCATGCTGGACTTCCAGGCCATGGGCATCCCGACCGTGGACTACGG
CAACAACATCCGCCAGGTGGCCTTCGACCAGGGCGTGAAAAACGCCTTTGATTTCCCCGGCTTTGTGCCCGCCTACATCC
GCCCGCTGTTCTGCGAAGGCAAGGGCCCGTTCCGCTGGGTCGCGCTCTCCGGCGATCCGGAAGACATCTACAAGACCGAC
GCCAAGATCAAGGAGCTGTTCCCCGAGAACAAGCACACGCACCGCTGGCTCGACATGGCGCGCGAGCGCATCGCCTTCCA
GGGCCTGCCCGCACGCATCTGCTGGCTGGGCCTGGGTGAACGCCACATTGCGGGTCTGGCCTTCAACGAGATGGTGAAGA
AGGGCGAGCTCAAGGCCCCGATCGTGATCGGCCGCGACCACCTGGACACCGGCTCGGTGGCCAGCCCGAACCGCGAGACC
GAGGCCATGAAGGACGGCACCGATGCCGTGTCCGACTGGCCGCTGCTCAACGCGCTGCTCAATGCCTCGGGCGGCGCCAC
CTGGGTCAGCCTGCACCACGGCGGCGGCGTGGGCATGGGTTACTCGCAGCATGCGGGCATGGTCATCGTGGCCGACGGCA
CCGATGCCGCCGCCGAGCGGCTGGCACGCGTGCTGGTCAACGACTGCGGCTCGGGCGTGATGCGCCATGCCGACGCGGGT
TACGAGATCGCCATTGCCACCGCGAAGAAGCAGGGCCTCAAGCTGCCGATGGTCCGGTGA

Upstream 100 bases:

>100_bases
GCCCTGCAGCAGATCCTGCCCAGCCACGCCACCGCGGCCTGACGCCGGGCCTGAACCTCAGCCTGAAACCCATTCCAACC
GTTTTATCCAGGAGACCGCC

Downstream 100 bases:

>100_bases
CTTGCGATAAAAAAAGGGAATCCTATTCCCAAATTTTGGGAATCAAGGGTTTGAATGCCGCCTGAATCCTTTGATACTGG
CGTCATGCTGATCAGCGCCT

Product: urocanate hydratase

Products: NA

Alternate protein names: Urocanase; Imidazolonepropionate hydrolase [H]

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MNAKDSFIAPTDAQSGTLTDPRVDPTRVIRAPRGSQLHCKSWLTEAAFRMIQNNLDPEVAENPQSLVVYGGIGRAARDWA
CFDQILASLKELNDDESLLVQSGKPVGVFKTHANAPRVLIANSNLVPKWANWEHFNELDRKGLFMYGQMTAGSWIYIGSQ
GIVQGTFETFVEAGRQHYNNSLAGKWILTAGLGGMGGAQPLAATLAGAVSLNIECQQSSIDFRLRTRYVDKQARDIDDAL
ALIKYHTDRKEAVSIALLGNAADILPELVKRAKAGAIKPDLVTDQTSAHDLINGYLPRGWNVAQWKAAQQDPAQHKRLTD
EAAQSCAVHVQAMLDFQAMGIPTVDYGNNIRQVAFDQGVKNAFDFPGFVPAYIRPLFCEGKGPFRWVALSGDPEDIYKTD
AKIKELFPENKHTHRWLDMARERIAFQGLPARICWLGLGERHIAGLAFNEMVKKGELKAPIVIGRDHLDTGSVASPNRET
EAMKDGTDAVSDWPLLNALLNASGGATWVSLHHGGGVGMGYSQHAGMVIVADGTDAAAERLARVLVNDCGSGVMRHADAG
YEIAIATAKKQGLKLPMVR

Sequences:

>Translated_579_residues
MNAKDSFIAPTDAQSGTLTDPRVDPTRVIRAPRGSQLHCKSWLTEAAFRMIQNNLDPEVAENPQSLVVYGGIGRAARDWA
CFDQILASLKELNDDESLLVQSGKPVGVFKTHANAPRVLIANSNLVPKWANWEHFNELDRKGLFMYGQMTAGSWIYIGSQ
GIVQGTFETFVEAGRQHYNNSLAGKWILTAGLGGMGGAQPLAATLAGAVSLNIECQQSSIDFRLRTRYVDKQARDIDDAL
ALIKYHTDRKEAVSIALLGNAADILPELVKRAKAGAIKPDLVTDQTSAHDLINGYLPRGWNVAQWKAAQQDPAQHKRLTD
EAAQSCAVHVQAMLDFQAMGIPTVDYGNNIRQVAFDQGVKNAFDFPGFVPAYIRPLFCEGKGPFRWVALSGDPEDIYKTD
AKIKELFPENKHTHRWLDMARERIAFQGLPARICWLGLGERHIAGLAFNEMVKKGELKAPIVIGRDHLDTGSVASPNRET
EAMKDGTDAVSDWPLLNALLNASGGATWVSLHHGGGVGMGYSQHAGMVIVADGTDAAAERLARVLVNDCGSGVMRHADAG
YEIAIATAKKQGLKLPMVR
>Mature_579_residues
MNAKDSFIAPTDAQSGTLTDPRVDPTRVIRAPRGSQLHCKSWLTEAAFRMIQNNLDPEVAENPQSLVVYGGIGRAARDWA
CFDQILASLKELNDDESLLVQSGKPVGVFKTHANAPRVLIANSNLVPKWANWEHFNELDRKGLFMYGQMTAGSWIYIGSQ
GIVQGTFETFVEAGRQHYNNSLAGKWILTAGLGGMGGAQPLAATLAGAVSLNIECQQSSIDFRLRTRYVDKQARDIDDAL
ALIKYHTDRKEAVSIALLGNAADILPELVKRAKAGAIKPDLVTDQTSAHDLINGYLPRGWNVAQWKAAQQDPAQHKRLTD
EAAQSCAVHVQAMLDFQAMGIPTVDYGNNIRQVAFDQGVKNAFDFPGFVPAYIRPLFCEGKGPFRWVALSGDPEDIYKTD
AKIKELFPENKHTHRWLDMARERIAFQGLPARICWLGLGERHIAGLAFNEMVKKGELKAPIVIGRDHLDTGSVASPNRET
EAMKDGTDAVSDWPLLNALLNASGGATWVSLHHGGGVGMGYSQHAGMVIVADGTDAAAERLARVLVNDCGSGVMRHADAG
YEIAIATAKKQGLKLPMVR

Specific function: Unknown

COG id: COG2987

COG function: function code E; Urocanate hydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urocanase family [H]

Homologues:

Organism=Homo sapiens, GI21389467, Length=598, Percent_Identity=33.2775919732441, Blast_Score=293, Evalue=2e-79,
Organism=Homo sapiens, GI260306182, Length=243, Percent_Identity=36.2139917695473, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71997891, Length=596, Percent_Identity=35.0671140939597, Blast_Score=317, Evalue=1e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000193 [H]

Pfam domain/function: PF01175 Urocanase [H]

EC number: =4.2.1.49 [H]

Molecular weight: Translated: 63095; Mature: 63095

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS01233 UROCANASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAKDSFIAPTDAQSGTLTDPRVDPTRVIRAPRGSQLHCKSWLTEAAFRMIQNNLDPEVA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHH
ENPQSLVVYGGIGRAARDWACFDQILASLKELNDDESLLVQSGKPVGVFKTHANAPRVLI
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCEEEE
ANSNLVPKWANWEHFNELDRKGLFMYGQMTAGSWIYIGSQGIVQGTFETFVEAGRQHYNN
ECCCCCCCCCCCHHHHHHCCCCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHCC
SLAGKWILTAGLGGMGGAQPLAATLAGAVSLNIECQQSSIDFRLRTRYVDKQARDIDDAL
CCCCCEEEEECCCCCCCCHHHHHHHHHEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHH
ALIKYHTDRKEAVSIALLGNAADILPELVKRAKAGAIKPDLVTDQTSAHDLINGYLPRGW
HHHHHCCCCHHEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCC
NVAQWKAAQQDPAQHKRLTDEAAQSCAVHVQAMLDFQAMGIPTVDYGNNIRQVAFDQGVK
CHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHCHH
NAFDFPGFVPAYIRPLFCEGKGPFRWVALSGDPEDIYKTDAKIKELFPENKHTHRWLDMA
HHCCCCCCCHHHHCEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
RERIAFQGLPARICWLGLGERHIAGLAFNEMVKKGELKAPIVIGRDHLDTGSVASPNRET
HHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCHH
EAMKDGTDAVSDWPLLNALLNASGGATWVSLHHGGGVGMGYSQHAGMVIVADGTDAAAER
HHHHCCCCHHHCCHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHH
LARVLVNDCGSGVMRHADAGYEIAIATAKKQGLKLPMVR
HHHHHHHHHCCHHHHHCCCCEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MNAKDSFIAPTDAQSGTLTDPRVDPTRVIRAPRGSQLHCKSWLTEAAFRMIQNNLDPEVA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHH
ENPQSLVVYGGIGRAARDWACFDQILASLKELNDDESLLVQSGKPVGVFKTHANAPRVLI
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCEEEE
ANSNLVPKWANWEHFNELDRKGLFMYGQMTAGSWIYIGSQGIVQGTFETFVEAGRQHYNN
ECCCCCCCCCCCHHHHHHCCCCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHCC
SLAGKWILTAGLGGMGGAQPLAATLAGAVSLNIECQQSSIDFRLRTRYVDKQARDIDDAL
CCCCCEEEEECCCCCCCCHHHHHHHHHEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHH
ALIKYHTDRKEAVSIALLGNAADILPELVKRAKAGAIKPDLVTDQTSAHDLINGYLPRGW
HHHHHCCCCHHEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCC
NVAQWKAAQQDPAQHKRLTDEAAQSCAVHVQAMLDFQAMGIPTVDYGNNIRQVAFDQGVK
CHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHCHH
NAFDFPGFVPAYIRPLFCEGKGPFRWVALSGDPEDIYKTDAKIKELFPENKHTHRWLDMA
HHCCCCCCCHHHHCEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
RERIAFQGLPARICWLGLGERHIAGLAFNEMVKKGELKAPIVIGRDHLDTGSVASPNRET
HHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCHH
EAMKDGTDAVSDWPLLNALLNASGGATWVSLHHGGGVGMGYSQHAGMVIVADGTDAAAER
HHHHCCCCHHHCCHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHH
LARVLVNDCGSGVMRHADAGYEIAIATAKKQGLKLPMVR
HHHHHHHHHCCHHHHHCCCCEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]