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The map label for this gene is glk [H]

Identifier: 91786652

GI number: 91786652

Start: 767529

End: 768374

Strand: Reverse

Name: glk [H]

Synonym: Bpro_0750

Alternate gene names: 91786652

Gene position: 768374-767529 (Counterclockwise)

Preceding gene: 91786653

Following gene: 91786648

Centisome position: 14.78

GC content: 61.94

Gene sequence:

>846_bases
ATGCTTGACCGAATCAAAGCTTCGTTACCCTCACTGGCCCCCGCGGAGCAACGCGTGGGCCGGTTGGTGCTGACTGATCC
GCGGGCGTTTGCCAACCTGCCCATCACCGAGTTGGCCAACCGCTCCCATGTCAGCAAGCCGACGGTGGTGCGCTTTTGCC
GCAGCATGGGTTATGACGGCCTGTCGGACTTCAAGCTCAAGCTGGCGGGCAGCGTGAGTGAGGGCGTACCTTTCATTCAC
CGCAGCGTGGATGCCGATGACAAGACCAGCGATGTGCTCGTGAAGGTCATCGATAACACCGTGGCCGCGTTTCTGAAGTA
CCGCAACGACGCGAGTTCGTTGGCCATTGAGAAAGCCGCCGATGCACTGCTGGCTACCTACAACACCGGCAAGCGCATCG
AGTTTTTCGGCGTGGGCAACTCCGGCATCGTGGCTCAGGACGCCCAGCACAAATTCTTCAGGCTGGGCATCACCAGCATC
GCCTACAGCGACGGCCACATGCAGGTCATGAGCGCCTCGCTGCTGGGCCCCGGCGACTGCGTGGTGGTGATTTCCAACTC
CGGCCGCACCCGCGACCTGATGGATGCCTGCGACATTGCCCGCAAGAACGGAGCGACCACGATTGTCATCACCGTGACCG
GTTCGCCGCTGGCAGCCGCCGGAAACATCCACCTGGCGGCCGACCATCCCGAAGGCTACGACCGCTACAGCCCCATGGTG
TCGCGCCTGATGCACCTGATGATCATCGACATCCTGGCCACCTGCGTGGCGCTGCGCATAGGCGCCAAGCTGCAGCCGCT
GCTCAAGGAAATGAAAAACAACCTGCGCAACAAGCGCTACGCCTGA

Upstream 100 bases:

>100_bases
AAGCCGGGGCCGCGGGACTGGCTTTGCCAGACCGCAGGCGCAGCGGCCCCCCCGGGGGGCAGGGAGTTACACGAAGTGAA
CGACCGTGGGGGCCATCCAC

Downstream 100 bases:

>100_bases
GGCCTGCCCCTCGCATTGCTTGCTCCCTCTCCCTCTGGGAGAGGGTTGGGGTGAGGGCCGCTGCCTATGAAAAAAGGGCC
GGATTTTTTCAGCCGCCGCA

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: Glucokinase; Glucose kinase; Putative HTH-type transcriptional regulator [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MLDRIKASLPSLAPAEQRVGRLVLTDPRAFANLPITELANRSHVSKPTVVRFCRSMGYDGLSDFKLKLAGSVSEGVPFIH
RSVDADDKTSDVLVKVIDNTVAAFLKYRNDASSLAIEKAADALLATYNTGKRIEFFGVGNSGIVAQDAQHKFFRLGITSI
AYSDGHMQVMSASLLGPGDCVVVISNSGRTRDLMDACDIARKNGATTIVITVTGSPLAAAGNIHLAADHPEGYDRYSPMV
SRLMHLMIIDILATCVALRIGAKLQPLLKEMKNNLRNKRYA

Sequences:

>Translated_281_residues
MLDRIKASLPSLAPAEQRVGRLVLTDPRAFANLPITELANRSHVSKPTVVRFCRSMGYDGLSDFKLKLAGSVSEGVPFIH
RSVDADDKTSDVLVKVIDNTVAAFLKYRNDASSLAIEKAADALLATYNTGKRIEFFGVGNSGIVAQDAQHKFFRLGITSI
AYSDGHMQVMSASLLGPGDCVVVISNSGRTRDLMDACDIARKNGATTIVITVTGSPLAAAGNIHLAADHPEGYDRYSPMV
SRLMHLMIIDILATCVALRIGAKLQPLLKEMKNNLRNKRYA
>Mature_281_residues
MLDRIKASLPSLAPAEQRVGRLVLTDPRAFANLPITELANRSHVSKPTVVRFCRSMGYDGLSDFKLKLAGSVSEGVPFIH
RSVDADDKTSDVLVKVIDNTVAAFLKYRNDASSLAIEKAADALLATYNTGKRIEFFGVGNSGIVAQDAQHKFFRLGITSI
AYSDGHMQVMSASLLGPGDCVVVISNSGRTRDLMDACDIARKNGATTIVITVTGSPLAAAGNIHLAADHPEGYDRYSPMV
SRLMHLMIIDILATCVALRIGAKLQPLLKEMKNNLRNKRYA

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=280, Percent_Identity=39.2857142857143, Blast_Score=204, Evalue=4e-54,
Organism=Escherichia coli, GI87082369, Length=229, Percent_Identity=30.1310043668122, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082130, Length=215, Percent_Identity=29.3023255813954, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788767, Length=268, Percent_Identity=24.6268656716418, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836
- InterPro:   IPR000843
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02685 Glucokinase; PF01418 HTH_6; PF01380 SIS [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 30402; Mature: 30402

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS00356 HTH_LACI_1 ; PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDRIKASLPSLAPAEQRVGRLVLTDPRAFANLPITELANRSHVSKPTVVRFCRSMGYDG
CCCCHHHCCCCCCCHHHHCCEEEEECCHHHHCCCHHHHHCCCCCCCHHHHHHHHHCCCCC
LSDFKLKLAGSVSEGVPFIHRSVDADDKTSDVLVKVIDNTVAAFLKYRNDASSLAIEKAA
CCCCEEEEECCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DALLATYNTGKRIEFFGVGNSGIVAQDAQHKFFRLGITSIAYSDGHMQVMSASLLGPGDC
HHHHEECCCCCEEEEEECCCCCCEECCHHHHHHHEEHHHEEECCCCCEEEEHHCCCCCCE
VVVISNSGRTRDLMDACDIARKNGATTIVITVTGSPLAAAGNIHLAADHPEGYDRYSPMV
EEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEECCCEEEEECCCCCHHHHHHHH
SRLMHLMIIDILATCVALRIGAKLQPLLKEMKNNLRNKRYA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLDRIKASLPSLAPAEQRVGRLVLTDPRAFANLPITELANRSHVSKPTVVRFCRSMGYDG
CCCCHHHCCCCCCCHHHHCCEEEEECCHHHHCCCHHHHHCCCCCCCHHHHHHHHHCCCCC
LSDFKLKLAGSVSEGVPFIHRSVDADDKTSDVLVKVIDNTVAAFLKYRNDASSLAIEKAA
CCCCEEEEECCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DALLATYNTGKRIEFFGVGNSGIVAQDAQHKFFRLGITSIAYSDGHMQVMSASLLGPGDC
HHHHEECCCCCEEEEEECCCCCCEECCHHHHHHHEEHHHEEECCCCCEEEEHHCCCCCCE
VVVISNSGRTRDLMDACDIARKNGATTIVITVTGSPLAAAGNIHLAADHPEGYDRYSPMV
EEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEECCCEEEEECCCCCHHHHHHHH
SRLMHLMIIDILATCVALRIGAKLQPLLKEMKNNLRNKRYA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA