Click here to switch to the map view.

The map label for this gene is siaT [H]

Identifier: 91786461

GI number: 91786461

Start: 553771

End: 555051

Strand: Direct

Name: siaT [H]

Synonym: Bpro_0555

Alternate gene names: 91786461

Gene position: 553771-555051 (Clockwise)

Preceding gene: 91786460

Following gene: 91786462

Centisome position: 10.65

GC content: 65.57

Gene sequence:

>1281_bases
ATGAGTCTCGCCGTCGTCATTGCCTTCATGCTGCTGGCCCTGCTCGGGCTGCCGATCGCCTTTGCGATGGGCGTGGCCGC
GCTCGGCGCCCTCTGGTACAGCGGGGTGGATTTTTCGATGGTGCCGCAGCGCATGATGCACGCCGTCAACTCCTTTCCGC
TGATGTCCATCCCCTTCTTTATGCTGGCCGGCGAGCTGATGATCAAGGCCGGCATCGTTGAGCGGCTCATCGCGCTGGCC
AACACCATGGTCGGCCGGGTGCGCGGCGGCATGGCGCATGTCACCATGCTGTCGGGCGCGGGCCTGGCTACCGTGTCCGG
TGCTGCCGTGTCGGATGCGAGCGCGCTGTCGTCGATGCTGGTCCCCTCGCTGACGAAAATCTACGACAAGGGTTTCGCCA
CCGCCATCGTCGCGGCGGCAGCCAACCTCGGGCCCATCATCCCGCCTTCCGGCGCGATGATCGTCTACGCCTTCATGGCC
GGCTCGTCTGTGTCGGTGGGCGGCATGTTCATGGCCGGCGTAGTGCCGGGCCTGCTGATCACCTTCGGTTTCATCGCGCT
GTGCTCGTGGATCGCCACGCGCCGCGGCTGGGCCGCCACCGGTGAGCCCTTCCGGCTGGCCACCGTGCTGGCCGAGCTGC
GCCGGTCGCTGATTGTGCTGGCCATGCCGGTCCTGGTGATCGGTGGCATCGTCGGCGGCGCCTTCACCGCCACCGAGGGC
TCGGCGATCGCGGTGGTTTACTCCACGGCGCTGGGCTTCTTTGTCACCCGCACGCTCAAGCTGGCCGACCTGCCCGGCAT
CGTGGTGCGTGCAGCCATCACCTCGGCCATGGTGGGCGCGCTGATCGCCTTTGCCTCCATCATCACCTACCTGATGACGG
TAGACCTGCTGCCGCAGCAACTCTCCGAATTGCTGCGCAGCCTCACCACCAGCCCGCTCGTCTTTCTGGTCCTGGTCTCG
GTGTTGTTGTTCGTCGTTGGCATGTTCCTGGAGTCGAACGCGGCCTACATCATGCTGGTGCCGCTGCTGCATCCGATTGC
GCTGCAATACGGCATTGATCCCTTGCACTTCGGATTCCTGTTCGTGCTCAACCTCGTGATCGGCATGCTCACGCCGCCCG
TCGGGGTGGTGCTGTTCGCCGTCTGCGGCATCACCGGCGTGCGCATGCGCGAGCTGGTCAGCAACCTCTGGCCCTTCATC
GTGCTGATGTACGGCGTGCTCGTGCTGTGCATGCTGGTGCCTTCCTTCGTCACTGCGCTGCCGCACGCGCTCGGCTACTG
A

Upstream 100 bases:

>100_bases
GGTTCATTGTGCCGGTGGGCCTGGGCGCGCTGCTGAGCGCGCTGCACCTGGTGCGCATCGTCATCGCGGGTGCGCCTGTG
CAGGCGCTGGGGAGTGCCGA

Downstream 100 bases:

>100_bases
ATTCATTTCCCGCGACCTGTCGCAATCTTTCATCAACTTTTAACCACTGGAGCTCACCATGTCATACCGTTCCCGCTTCA
AGATTCTTGCCGCCGTGGCC

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MSLAVVIAFMLLALLGLPIAFAMGVAALGALWYSGVDFSMVPQRMMHAVNSFPLMSIPFFMLAGELMIKAGIVERLIALA
NTMVGRVRGGMAHVTMLSGAGLATVSGAAVSDASALSSMLVPSLTKIYDKGFATAIVAAAANLGPIIPPSGAMIVYAFMA
GSSVSVGGMFMAGVVPGLLITFGFIALCSWIATRRGWAATGEPFRLATVLAELRRSLIVLAMPVLVIGGIVGGAFTATEG
SAIAVVYSTALGFFVTRTLKLADLPGIVVRAAITSAMVGALIAFASIITYLMTVDLLPQQLSELLRSLTTSPLVFLVLVS
VLLFVVGMFLESNAAYIMLVPLLHPIALQYGIDPLHFGFLFVLNLVIGMLTPPVGVVLFAVCGITGVRMRELVSNLWPFI
VLMYGVLVLCMLVPSFVTALPHALGY

Sequences:

>Translated_426_residues
MSLAVVIAFMLLALLGLPIAFAMGVAALGALWYSGVDFSMVPQRMMHAVNSFPLMSIPFFMLAGELMIKAGIVERLIALA
NTMVGRVRGGMAHVTMLSGAGLATVSGAAVSDASALSSMLVPSLTKIYDKGFATAIVAAAANLGPIIPPSGAMIVYAFMA
GSSVSVGGMFMAGVVPGLLITFGFIALCSWIATRRGWAATGEPFRLATVLAELRRSLIVLAMPVLVIGGIVGGAFTATEG
SAIAVVYSTALGFFVTRTLKLADLPGIVVRAAITSAMVGALIAFASIITYLMTVDLLPQQLSELLRSLTTSPLVFLVLVS
VLLFVVGMFLESNAAYIMLVPLLHPIALQYGIDPLHFGFLFVLNLVIGMLTPPVGVVLFAVCGITGVRMRELVSNLWPFI
VLMYGVLVLCMLVPSFVTALPHALGY
>Mature_425_residues
SLAVVIAFMLLALLGLPIAFAMGVAALGALWYSGVDFSMVPQRMMHAVNSFPLMSIPFFMLAGELMIKAGIVERLIALAN
TMVGRVRGGMAHVTMLSGAGLATVSGAAVSDASALSSMLVPSLTKIYDKGFATAIVAAAANLGPIIPPSGAMIVYAFMAG
SSVSVGGMFMAGVVPGLLITFGFIALCSWIATRRGWAATGEPFRLATVLAELRRSLIVLAMPVLVIGGIVGGAFTATEGS
AIAVVYSTALGFFVTRTLKLADLPGIVVRAAITSAMVGALIAFASIITYLMTVDLLPQQLSELLRSLTTSPLVFLVLVSV
LLFVVGMFLESNAAYIMLVPLLHPIALQYGIDPLHFGFLFVLNLVIGMLTPPVGVVLFAVCGITGVRMRELVSNLWPFIV
LMYGVLVLCMLVPSFVTALPHALGY

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=392, Percent_Identity=31.6326530612245, Blast_Score=182, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 44595; Mature: 44464

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCC
>Mature Secondary Structure 
SLAVVIAFMLLALLGLPIAFAMGVAALGALWYSGVDFSMVPQRMMHAVNSFPLMSIPFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHH
MLAGELMIKAGIVERLIALANTMVGRVRGGMAHVTMLSGAGLATVSGAAVSDASALSSML
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHCCCCHHHHHHHHHHHH
VPSLTKIYDKGFATAIVAAAANLGPIIPPSGAMIVYAFMAGSSVSVGGMFMAGVVPGLLI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEHHHHCCCCCCHHHHHHHHHHHHHHH
TFGFIALCSWIATRRGWAATGEPFRLATVLAELRRSLIVLAMPVLVIGGIVGGAFTATEG
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCC
SAIAVVYSTALGFFVTRTLKLADLPGIVVRAAITSAMVGALIAFASIITYLMTVDLLPQQ
CEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSELLRSLTTSPLVFLVLVSVLLFVVGMFLESNAAYIMLVPLLHPIALQYGIDPLHFGFL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCHHHHHHH
FVLNLVIGMLTPPVGVVLFAVCGITGVRMRELVSNLWPFIVLMYGVLVLCMLVPSFVTAL
HHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PHALGY
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]