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The map label for this gene is lplA1 [H]

Identifier: 89898691

GI number: 89898691

Start: 1040202

End: 1040906

Strand: Direct

Name: lplA1 [H]

Synonym: CF0884

Alternate gene names: 89898691

Gene position: 1040202-1040906 (Clockwise)

Preceding gene: 89898690

Following gene: 89898731

Centisome position: 89.19

GC content: 38.01

Gene sequence:

>705_bases
ATGCGCATAAATAAGTGTATTTTCTTAAATCTATCTGGGAAAACTATCTTTGAGCAGCTGCAAATAGAAGAAGCCCTTCT
TCGCAACAGCAGAGAAAATTACTGTATTATTAATTTTGATGCACCTGAAGCTGTGGTTTTAGGTATTTCAAGACTCCCAC
AAGAAGATCTTTATCTTCCAGAATTACGATCCGATAATATTCCTATAATTAAGCGTTACAGTGGTGGAGGAACAGTATTT
ATCGATAAAAATAGTTTATTCGTAACGTGGATTATGAACTCTTCAGAACCCATGGCCAATTCTCAAGATTTGATGCATTG
GTCTTATGAAATTTACTCCCCTATTTTCCCAAAGACATTTTCCATTAACGAAAATGATTATACTTTAGAAGAGAAGAAAA
TCGCAGGAAATGCCCAATATATCCAAAAATCTCGCTGGGTACACCATACAACATTTCTCTGGGATATGGATATAGAGAAG
CTTTCTCGTTATCTACCAATACCCCAAAAACAACCGTCGTACAGGAAACAACGTCTACATCGAGATTTCCTCACAACTAT
TCGTCCGTGGTTCCCTACCAGAGAAAGCTTTTTCGAGAAATTAAAAGCATCAGCAGGTAGAGCTTTTCATTGGAGCGCCC
TTTCAGAAAATGAGCTGAAGGACCTTCTAGAAACGCCCCACCGAAAGTCCACCACTTTATTGTAA

Upstream 100 bases:

>100_bases
AAACTAGCTAAATTTACCCCAAGGACGATAGGGTCAGCATCGAGAATATCGGGCATAGCTAATGCTGATATTCAAGTATT
GATGGTTGCTGTAAAAAAAC

Downstream 100 bases:

>100_bases
AACTATTTCCTTCTACTCAACAGAATTAACGATTTCGGTTTTGCTGAAGAAATAGCTAATTTCTATAGCTGCGTTTTCCA
AACTGTCAGATCCGTGTACA

Product: lipoate protein ligase A

Products: NA

Alternate protein names: Lipoate--protein ligase [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MRINKCIFLNLSGKTIFEQLQIEEALLRNSRENYCIINFDAPEAVVLGISRLPQEDLYLPELRSDNIPIIKRYSGGGTVF
IDKNSLFVTWIMNSSEPMANSQDLMHWSYEIYSPIFPKTFSINENDYTLEEKKIAGNAQYIQKSRWVHHTTFLWDMDIEK
LSRYLPIPQKQPSYRKQRLHRDFLTTIRPWFPTRESFFEKLKASAGRAFHWSALSENELKDLLETPHRKSTTLL

Sequences:

>Translated_234_residues
MRINKCIFLNLSGKTIFEQLQIEEALLRNSRENYCIINFDAPEAVVLGISRLPQEDLYLPELRSDNIPIIKRYSGGGTVF
IDKNSLFVTWIMNSSEPMANSQDLMHWSYEIYSPIFPKTFSINENDYTLEEKKIAGNAQYIQKSRWVHHTTFLWDMDIEK
LSRYLPIPQKQPSYRKQRLHRDFLTTIRPWFPTRESFFEKLKASAGRAFHWSALSENELKDLLETPHRKSTTLL
>Mature_234_residues
MRINKCIFLNLSGKTIFEQLQIEEALLRNSRENYCIINFDAPEAVVLGISRLPQEDLYLPELRSDNIPIIKRYSGGGTVF
IDKNSLFVTWIMNSSEPMANSQDLMHWSYEIYSPIFPKTFSINENDYTLEEKKIAGNAQYIQKSRWVHHTTFLWDMDIEK
LSRYLPIPQKQPSYRKQRLHRDFLTTIRPWFPTRESFFEKLKASAGRAFHWSALSENELKDLLETPHRKSTTLL

Specific function: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes [H]

COG id: COG0095

COG function: function code H; Lipoate-protein ligase A

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lplA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004143
- InterPro:   IPR005107
- InterPro:   IPR019491
- InterPro:   IPR004562 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB; PF10437 Lip_prot_lig_C [H]

EC number: =2.7.7.63 [H]

Molecular weight: Translated: 27596; Mature: 27596

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRINKCIFLNLSGKTIFEQLQIEEALLRNSRENYCIINFDAPEAVVLGISRLPQEDLYLP
CCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEHHHCCCCCCCCC
ELRSDNIPIIKRYSGGGTVFIDKNSLFVTWIMNSSEPMANSQDLMHWSYEIYSPIFPKTF
CCCCCCCCEEEEECCCEEEEEECCCEEEEEEECCCCCCCCCCHHHEEHHHHCCCCCCCEE
SINENDYTLEEKKIAGNAQYIQKSRWVHHTTFLWDMDIEKLSRYLPIPQKQPSYRKQRLH
ECCCCCCEEHHHHHCCCHHHHHHCCCEEEEEEEEECCHHHHHHHCCCCCCCCHHHHHHHH
RDFLTTIRPWFPTRESFFEKLKASAGRAFHWSALSENELKDLLETPHRKSTTLL
HHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRINKCIFLNLSGKTIFEQLQIEEALLRNSRENYCIINFDAPEAVVLGISRLPQEDLYLP
CCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEHHHCCCCCCCCC
ELRSDNIPIIKRYSGGGTVFIDKNSLFVTWIMNSSEPMANSQDLMHWSYEIYSPIFPKTF
CCCCCCCCEEEEECCCEEEEEECCCEEEEEEECCCCCCCCCCHHHEEHHHHCCCCCCCEE
SINENDYTLEEKKIAGNAQYIQKSRWVHHTTFLWDMDIEKLSRYLPIPQKQPSYRKQRLH
ECCCCCCEEHHHHHCCCHHHHHHCCCEEEEEEEEECCHHHHHHHCCCCCCCCHHHHHHHH
RDFLTTIRPWFPTRESFFEKLKASAGRAFHWSALSENELKDLLETPHRKSTTLL
HHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7569993 [H]