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The map label for this gene is hrcA [H]

Identifier: 89898570

GI number: 89898570

Start: 907461

End: 908621

Strand: Direct

Name: hrcA [H]

Synonym: CF0763

Alternate gene names: 89898570

Gene position: 907461-908621 (Clockwise)

Preceding gene: 89898569

Following gene: 89898571

Centisome position: 77.81

GC content: 40.31

Gene sequence:

>1161_bases
ATGTCCAGGTCATGGATCTCAAAACGAGAGTCTAAGATTCTTTACATACTCTTAACGACGACAGAGCTGTATTTAAAAAC
AGGTCAGCCGGTCGGGTCAAAAACACTGAAGGAATACGAATGCTCGAATTTGAGCACCGCAACGATTCGTAATTATTTTT
CAGAGTTAGAATCAGAAGGGTTTTTAAAGAAAAATCATATTTCCGGGGGAAGAATCCCTACGGATTTGGCTTTTCGTTAT
TATGTAGACCATTGTGCAGATTTTTCTCAGTCAGAGCTTCCTGAGAGCACAACACGCCTATTGAATCAACTCCCTGAAGA
AAGTCAAAACATTGTGAAAGATTTACAAAAGGCTTTGGAAATCCTGGGAGAGGCTCTACAGCTCCCCACCTGTTTTTCTT
CACCGCGATTTGAAAACGACTCTATAACCAACATCCAGATTTCTCTAGTAGATGAACAACGGGTAGTTGTAATTCTGTCT
ACAGAATTTGGTCAGGTATTTACAGAAACTTTATGGCTACCAGAAACCTCAAGTCCAGCCTCTGTAAAGCGTATTGAAAC
ATTTCTTCAAAGTTATGTGCGTAAACAACCTCCTACAGAGATTCTTTCTCAAAAAGAAGAAGATCTAGGAATGACTCTAT
ATAATGAAGTTGTCGTGCGTTATCTCACCCGGTACTGTAATTTCAGCGAGGAAGATTTATACCAAACAGGATTATCCAAA
CTTCTCAAATACGACGCTTTCAAAGACCCCGACACACTAGCCTTGGGATTATCATTTTTCGAGAATCGCCGCCATATGTG
CAAACTTTTAGATATTGGCATGCACAGAGATCGCCCCACGGCATTTATAGGCAATGAGCTCTCGACAATTTTTGGAACTC
CTAACCCACAGTGTGCGGTAATTACGACTCCCTATTATATGAATCGTACTCCTTTAGGAGCCTTTGGTGTACTGGGTCCT
ATAAATCTTCCCTACAGGGAGATTTTCCAAACCCTCACAATATTTGCAGATAAAGTTAAAGATAGCCTGACACAAAGTTT
TTATAAGTTTAAATTATCCTTCAGAAGACCTTGTCCTTCCGATCCTAAACTCTCTAAAGAACCCACGTTACTGGCAAGAT
ACTCTTCTATAAAACTATTACCCCCCAAGGAGACTTCATGA

Upstream 100 bases:

>100_bases
TAGCATTCTTTAGAGGTGAGTGCTAAACTTCCTTGACCTCGGAGGGTCGTTTTCCTATAATAATCGCCAGAGAACAGATT
ATTTGTGTTGGAAAACAGTT

Downstream 100 bases:

>100_bases
CAGATTCCTCTAACGAACATGAAACAGAAAATCCATCAGTTCCTAACCCCGATAACGAGATTCAGGATCTCCAACAAGAA
ATAGCGACGTTAAAAGCTGA

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MSRSWISKRESKILYILLTTTELYLKTGQPVGSKTLKEYECSNLSTATIRNYFSELESEGFLKKNHISGGRIPTDLAFRY
YVDHCADFSQSELPESTTRLLNQLPEESQNIVKDLQKALEILGEALQLPTCFSSPRFENDSITNIQISLVDEQRVVVILS
TEFGQVFTETLWLPETSSPASVKRIETFLQSYVRKQPPTEILSQKEEDLGMTLYNEVVVRYLTRYCNFSEEDLYQTGLSK
LLKYDAFKDPDTLALGLSFFENRRHMCKLLDIGMHRDRPTAFIGNELSTIFGTPNPQCAVITTPYYMNRTPLGAFGVLGP
INLPYREIFQTLTIFADKVKDSLTQSFYKFKLSFRRPCPSDPKLSKEPTLLARYSSIKLLPPKETS

Sequences:

>Translated_386_residues
MSRSWISKRESKILYILLTTTELYLKTGQPVGSKTLKEYECSNLSTATIRNYFSELESEGFLKKNHISGGRIPTDLAFRY
YVDHCADFSQSELPESTTRLLNQLPEESQNIVKDLQKALEILGEALQLPTCFSSPRFENDSITNIQISLVDEQRVVVILS
TEFGQVFTETLWLPETSSPASVKRIETFLQSYVRKQPPTEILSQKEEDLGMTLYNEVVVRYLTRYCNFSEEDLYQTGLSK
LLKYDAFKDPDTLALGLSFFENRRHMCKLLDIGMHRDRPTAFIGNELSTIFGTPNPQCAVITTPYYMNRTPLGAFGVLGP
INLPYREIFQTLTIFADKVKDSLTQSFYKFKLSFRRPCPSDPKLSKEPTLLARYSSIKLLPPKETS
>Mature_385_residues
SRSWISKRESKILYILLTTTELYLKTGQPVGSKTLKEYECSNLSTATIRNYFSELESEGFLKKNHISGGRIPTDLAFRYY
VDHCADFSQSELPESTTRLLNQLPEESQNIVKDLQKALEILGEALQLPTCFSSPRFENDSITNIQISLVDEQRVVVILST
EFGQVFTETLWLPETSSPASVKRIETFLQSYVRKQPPTEILSQKEEDLGMTLYNEVVVRYLTRYCNFSEEDLYQTGLSKL
LKYDAFKDPDTLALGLSFFENRRHMCKLLDIGMHRDRPTAFIGNELSTIFGTPNPQCAVITTPYYMNRTPLGAFGVLGPI
NLPYREIFQTLTIFADKVKDSLTQSFYKFKLSFRRPCPSDPKLSKEPTLLARYSSIKLLPPKETS

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 44160; Mature: 44029

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSWISKRESKILYILLTTTELYLKTGQPVGSKTLKEYECSNLSTATIRNYFSELESEG
CCCHHHHHCCCCEEEEEEEEEEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCC
FLKKNHISGGRIPTDLAFRYYVDHCADFSQSELPESTTRLLNQLPEESQNIVKDLQKALE
CEECCCCCCCCCCHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
ILGEALQLPTCFSSPRFENDSITNIQISLVDEQRVVVILSTEFGQVFTETLWLPETSSPA
HHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEEEECCHHHHHHHHHCCCCCCCCH
SVKRIETFLQSYVRKQPPTEILSQKEEDLGMTLYNEVVVRYLTRYCNFSEEDLYQTGLSK
HHHHHHHHHHHHHHCCCCHHHHCCCHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LLKYDAFKDPDTLALGLSFFENRRHMCKLLDIGMHRDRPTAFIGNELSTIFGTPNPQCAV
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHCCCCCCCEEE
ITTPYYMNRTPLGAFGVLGPINLPYREIFQTLTIFADKVKDSLTQSFYKFKLSFRRPCPS
EECCCEECCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DPKLSKEPTLLARYSSIKLLPPKETS
CCCCCCCCCCEEECCCEEECCCCCCC
>Mature Secondary Structure 
SRSWISKRESKILYILLTTTELYLKTGQPVGSKTLKEYECSNLSTATIRNYFSELESEG
CCHHHHHCCCCEEEEEEEEEEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCC
FLKKNHISGGRIPTDLAFRYYVDHCADFSQSELPESTTRLLNQLPEESQNIVKDLQKALE
CEECCCCCCCCCCHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
ILGEALQLPTCFSSPRFENDSITNIQISLVDEQRVVVILSTEFGQVFTETLWLPETSSPA
HHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEEEECCHHHHHHHHHCCCCCCCCH
SVKRIETFLQSYVRKQPPTEILSQKEEDLGMTLYNEVVVRYLTRYCNFSEEDLYQTGLSK
HHHHHHHHHHHHHHCCCCHHHHCCCHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LLKYDAFKDPDTLALGLSFFENRRHMCKLLDIGMHRDRPTAFIGNELSTIFGTPNPQCAV
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHCCCCCCCEEE
ITTPYYMNRTPLGAFGVLGPINLPYREIFQTLTIFADKVKDSLTQSFYKFKLSFRRPCPS
EECCCEECCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DPKLSKEPTLLARYSSIKLLPPKETS
CCCCCCCCCCEEECCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12056482 [H]