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The map label for this gene is devB [H]

Identifier: 89898276

GI number: 89898276

Start: 557198

End: 557980

Strand: Direct

Name: devB [H]

Synonym: CF0469

Alternate gene names: 89898276

Gene position: 557198-557980 (Clockwise)

Preceding gene: 89898275

Following gene: 89898281

Centisome position: 47.78

GC content: 37.68

Gene sequence:

>783_bases
ATGTTTATGGCAACATTAGTTAACTTTAATGATACGAACAAACTACTCCTCACAAAAAAACCAGAATTGTTTATTGATTT
GGCTAGTAAAGATTGGATTGCTAGTGCGAATAAATCGATAAGGCAGCAAGGAGCTTTCTATGTTGCGCTTTCAGGCGGGA
GAACTCCTTTAGAAATTTTTAAAGACATCGTAACGAATAAAGAAAAACTTTCTGATCCCACGAAGATCTTTTTATTTTGG
GGAGATGAAAGAAATGTCCCCCACACATCTTCAGAAAGTAATTATGGTCAGGCAATGAGTATACTTCGGGAGCTAGATAT
TCCTGAAGAGCAGATTTTCCGTATGGAAACTGAAAACCCTAACGGGGCTAGGAAATACCAAAACCTTATAGAATCTACAG
TCCCAGAGGTAAGTTTTGATATGGTTATGCTGGGTCTTGGTGAAGATGGTCATACCCTATCTCTCTTTCCAAATACACAG
GCCTTAAATGAACACGAACGCCTAGTCGTTTTTAATGAGGTTCCTCAATTAGAAACAGAGAGAATGACACTCACACTCCC
CGTTGTGCATAAAGCAAAACATGTAGTTGTTTATGTCCAGGGGGAAAATAAAAAAGCTATAGTAAAGAGCATTTTTTTCC
CAGAAGATAAAAAGGCTCAGTCTTATCCTATAGAACTTATTGGACAAGCAAGAACCCCCTTGTTTTGGATTCTTGCTGCA
GATGCTTATGATTTGAAAGACTTCGACCAGATTTCTTCTCTCTATAAATTAGACATTATCTAA

Upstream 100 bases:

>100_bases
CTAATTATGTTGCCGGATCTTCAGGCCCCAAAGAAGCTGAGGAATTACTACAGGCAGATGGAAGGAATTGGCGTCCTCTG
TAATTTAACTTTATTATGAG

Downstream 100 bases:

>100_bases
ATTTATAGGTTCAGTAAGATATTCAAAGATCAGGAAATATACCTCTCCTAGTTAAGTTTGCGAGGATCGTACTACCTCGT
CATAACTTGGTGGGGGCTCC

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MFMATLVNFNDTNKLLLTKKPELFIDLASKDWIASANKSIRQQGAFYVALSGGRTPLEIFKDIVTNKEKLSDPTKIFLFW
GDERNVPHTSSESNYGQAMSILRELDIPEEQIFRMETENPNGARKYQNLIESTVPEVSFDMVMLGLGEDGHTLSLFPNTQ
ALNEHERLVVFNEVPQLETERMTLTLPVVHKAKHVVVYVQGENKKAIVKSIFFPEDKKAQSYPIELIGQARTPLFWILAA
DAYDLKDFDQISSLYKLDII

Sequences:

>Translated_260_residues
MFMATLVNFNDTNKLLLTKKPELFIDLASKDWIASANKSIRQQGAFYVALSGGRTPLEIFKDIVTNKEKLSDPTKIFLFW
GDERNVPHTSSESNYGQAMSILRELDIPEEQIFRMETENPNGARKYQNLIESTVPEVSFDMVMLGLGEDGHTLSLFPNTQ
ALNEHERLVVFNEVPQLETERMTLTLPVVHKAKHVVVYVQGENKKAIVKSIFFPEDKKAQSYPIELIGQARTPLFWILAA
DAYDLKDFDQISSLYKLDII
>Mature_260_residues
MFMATLVNFNDTNKLLLTKKPELFIDLASKDWIASANKSIRQQGAFYVALSGGRTPLEIFKDIVTNKEKLSDPTKIFLFW
GDERNVPHTSSESNYGQAMSILRELDIPEEQIFRMETENPNGARKYQNLIESTVPEVSFDMVMLGLGEDGHTLSLFPNTQ
ALNEHERLVVFNEVPQLETERMTLTLPVVHKAKHVVVYVQGENKKAIVKSIFFPEDKKAQSYPIELIGQARTPLFWILAA
DAYDLKDFDQISSLYKLDII

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=237, Percent_Identity=32.4894514767932, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI6912586, Length=170, Percent_Identity=35.8823529411765, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115533058, Length=204, Percent_Identity=32.843137254902, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115533060, Length=203, Percent_Identity=32.512315270936, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6321687, Length=222, Percent_Identity=31.981981981982, Blast_Score=89, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6321957, Length=210, Percent_Identity=30.4761904761905, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324362, Length=229, Percent_Identity=28.82096069869, Blast_Score=73, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319918, Length=215, Percent_Identity=27.906976744186, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641119, Length=214, Percent_Identity=34.1121495327103, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 29644; Mature: 29644

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMATLVNFNDTNKLLLTKKPELFIDLASKDWIASANKSIRQQGAFYVALSGGRTPLEIF
CEEEEEEEECCCCEEEEEECCCEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHH
KDIVTNKEKLSDPTKIFLFWGDERNVPHTSSESNYGQAMSILRELDIPEEQIFRMETENP
HHHHCCHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHEEEECCCC
NGARKYQNLIESTVPEVSFDMVMLGLGEDGHTLSLFPNTQALNEHERLVVFNEVPQLETE
CHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCC
RMTLTLPVVHKAKHVVVYVQGENKKAIVKSIFFPEDKKAQSYPIELIGQARTPLFWILAA
EEEEEEEEEECCCEEEEEEECCCCCEEHHHHCCCCCCCCCCCCCEEECCCCCCEEEEEEC
DAYDLKDFDQISSLYKLDII
CCCCCCCHHHHHHHEEEECC
>Mature Secondary Structure
MFMATLVNFNDTNKLLLTKKPELFIDLASKDWIASANKSIRQQGAFYVALSGGRTPLEIF
CEEEEEEEECCCCEEEEEECCCEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHH
KDIVTNKEKLSDPTKIFLFWGDERNVPHTSSESNYGQAMSILRELDIPEEQIFRMETENP
HHHHCCHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHEEEECCCC
NGARKYQNLIESTVPEVSFDMVMLGLGEDGHTLSLFPNTQALNEHERLVVFNEVPQLETE
CHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCC
RMTLTLPVVHKAKHVVVYVQGENKKAIVKSIFFPEDKKAQSYPIELIGQARTPLFWILAA
EEEEEEEEEECCCEEEEEEECCCCCEEHHHHCCCCCCCCCCCCCEEECCCCCCEEEEEEC
DAYDLKDFDQISSLYKLDII
CCCCCCCHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]