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The map label for this gene is gcp2

Identifier: 89898273

GI number: 89898273

Start: 552861

End: 553895

Strand: Direct

Name: gcp2

Synonym: CF0466

Alternate gene names: 89898273

Gene position: 552861-553895 (Clockwise)

Preceding gene: 89898269

Following gene: 89898274

Centisome position: 47.41

GC content: 41.84

Gene sequence:

>1035_bases
ATGCTTACCCTTGGGTTGGAAAGCTCTTGTGATGAGACGGCATGTGCTTTAGTAGATGCCGATGCGCAAATTGTGGCTAA
TGTAGTCTCCTCGCAACAGTATCACGCTTCTTACGGGGGCGTTGTCCCTGAGCTGGCTTCTAGGGCCCATCTCCAAATGC
TTCCTTCTGTGGTAAATTCTGCTTTAGAAAAGTCCGGAGTTTCTTTGGACGATATTGATCTTATCGCTGTGACGCATACT
CCAGGATTGATAGGTTCCTTGGCCGTAGGCGTAAATTTTGCTAAAGGATTGGCTATAGGATCTCAAAAACCTATGATCGG
AGTTAATCACGTTGAGGCTCATCTTTACGCGGCTTATATGGAAGCAAAAAATGTAGAATTTCCTGCATTAGGATTGGTGA
TGTCCGGAGCCCACACCTCCATGTTTTTGATGGAAGACCCTTTAAGTTATAAGTTAATAGGGAATACCCGAGATGATGCT
ATCGGCGAAACTTTTGACAAAGTGGGGCGATTTCTAGGACTTCCTTATCCAGGGGGGGCCTTAATAGAAATGATGGCATC
TCAAGGATGCGAAGAATCTTACCCTTTTTCTGCTGCTAAAGTTCCTGGGTATGATTTATCTTTTAGTGGATTAAAAACAG
CGGTTCTTTACGCAATTAAAGGGAATAATAGTAATAGCAGATCCCCTCTTCCGGACCTTTCTCAAAAAGAAAAAAACAAT
ATTGCAGCCTCTTTCCAAAAAGCGGCTTTTATGACAATTGCACAAAAACTTCCTAAAATTATAAAAAATTTTTCTTGCAG
GTCCATCCTGGTTGGAGGAGGGGTAGCAAACAATAAGTATTTCCAGACCTTATTGCAAAATACTTTAAATTTGCCTTTAT
ATTTTCCTTCTTCTAAGTTATGCACGGATAATGCTGCGATGATTGCAGGATTAGGAAGAGAGCTGTTTCTCTCAAGAAAA
ACTACCCAAGGAATTACTCCATGCGCAAGATATCGTTGGGAATCTGTTGCGGACTCCTTATCTCCTCATCCCTAA

Upstream 100 bases:

>100_bases
TGCGACATTTTTTTTCATTTGGCCTCTCGAAGTTTTCCTTGCTGATATTCAGAAGAGCACTTTACTATAGAGTACTGGTT
TATATTTTTCTTTGGTTTTT

Downstream 100 bases:

>100_bases
CGATTCATGGATGTAAAAGCCTTCGAACATCACAAGAACGTATCTCAATAAATATAAATATGAAAGACGATCCGAGGTCT
TTTGACCCTCGCGAAGTCCG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MLTLGLESSCDETACALVDADAQIVANVVSSQQYHASYGGVVPELASRAHLQMLPSVVNSALEKSGVSLDDIDLIAVTHT
PGLIGSLAVGVNFAKGLAIGSQKPMIGVNHVEAHLYAAYMEAKNVEFPALGLVMSGAHTSMFLMEDPLSYKLIGNTRDDA
IGETFDKVGRFLGLPYPGGALIEMMASQGCEESYPFSAAKVPGYDLSFSGLKTAVLYAIKGNNSNSRSPLPDLSQKEKNN
IAASFQKAAFMTIAQKLPKIIKNFSCRSILVGGGVANNKYFQTLLQNTLNLPLYFPSSKLCTDNAAMIAGLGRELFLSRK
TTQGITPCARYRWESVADSLSPHP

Sequences:

>Translated_344_residues
MLTLGLESSCDETACALVDADAQIVANVVSSQQYHASYGGVVPELASRAHLQMLPSVVNSALEKSGVSLDDIDLIAVTHT
PGLIGSLAVGVNFAKGLAIGSQKPMIGVNHVEAHLYAAYMEAKNVEFPALGLVMSGAHTSMFLMEDPLSYKLIGNTRDDA
IGETFDKVGRFLGLPYPGGALIEMMASQGCEESYPFSAAKVPGYDLSFSGLKTAVLYAIKGNNSNSRSPLPDLSQKEKNN
IAASFQKAAFMTIAQKLPKIIKNFSCRSILVGGGVANNKYFQTLLQNTLNLPLYFPSSKLCTDNAAMIAGLGRELFLSRK
TTQGITPCARYRWESVADSLSPHP
>Mature_344_residues
MLTLGLESSCDETACALVDADAQIVANVVSSQQYHASYGGVVPELASRAHLQMLPSVVNSALEKSGVSLDDIDLIAVTHT
PGLIGSLAVGVNFAKGLAIGSQKPMIGVNHVEAHLYAAYMEAKNVEFPALGLVMSGAHTSMFLMEDPLSYKLIGNTRDDA
IGETFDKVGRFLGLPYPGGALIEMMASQGCEESYPFSAAKVPGYDLSFSGLKTAVLYAIKGNNSNSRSPLPDLSQKEKNN
IAASFQKAAFMTIAQKLPKIIKNFSCRSILVGGGVANNKYFQTLLQNTLNLPLYFPSSKLCTDNAAMIAGLGRELFLSRK
TTQGITPCARYRWESVADSLSPHP

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=336, Percent_Identity=33.6309523809524, Blast_Score=148, Evalue=6e-36,
Organism=Homo sapiens, GI8923380, Length=345, Percent_Identity=26.9565217391304, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1789445, Length=339, Percent_Identity=36.8731563421829, Blast_Score=220, Evalue=9e-59,
Organism=Caenorhabditis elegans, GI17557464, Length=365, Percent_Identity=29.5890410958904, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71995670, Length=346, Percent_Identity=26.5895953757225, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320099, Length=365, Percent_Identity=30.6849315068493, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6322891, Length=344, Percent_Identity=25, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI20129063, Length=359, Percent_Identity=32.3119777158774, Blast_Score=174, Evalue=7e-44,
Organism=Drosophila melanogaster, GI21357207, Length=325, Percent_Identity=25.5384615384615, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_CHLFF (Q254Q0)

Other databases:

- EMBL:   AP006861
- RefSeq:   YP_515383.1
- ProteinModelPortal:   Q254Q0
- SMR:   Q254Q0
- STRING:   Q254Q0
- MEROPS:   M22.001
- GeneID:   3959197
- GenomeReviews:   AP006861_GR
- KEGG:   cfe:CF0466
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- BioCyc:   CFEL264202:CF0466-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36720; Mature: 36720

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLGLESSCDETACALVDADAQIVANVVSSQQYHASYGGVVPELASRAHLQMLPSVVNS
CEEECCCCCCCCHHHEEECCCHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ALEKSGVSLDDIDLIAVTHTPGLIGSLAVGVNFAKGLAIGSQKPMIGVNHVEAHLYAAYM
HHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHH
EAKNVEFPALGLVMSGAHTSMFLMEDPLSYKLIGNTRDDAIGETFDKVGRFLGLPYPGGA
HHCCCCCCHHHEEECCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCHH
LIEMMASQGCEESYPFSAAKVPGYDLSFSGLKTAVLYAIKGNNSNSRSPLPDLSQKEKNN
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHH
IAASFQKAAFMTIAQKLPKIIKNFSCRSILVGGGVANNKYFQTLLQNTLNLPLYFPSSKL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCC
CTDNAAMIAGLGRELFLSRKTTQGITPCARYRWESVADSLSPHP
CCCCHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLTLGLESSCDETACALVDADAQIVANVVSSQQYHASYGGVVPELASRAHLQMLPSVVNS
CEEECCCCCCCCHHHEEECCCHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ALEKSGVSLDDIDLIAVTHTPGLIGSLAVGVNFAKGLAIGSQKPMIGVNHVEAHLYAAYM
HHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHH
EAKNVEFPALGLVMSGAHTSMFLMEDPLSYKLIGNTRDDAIGETFDKVGRFLGLPYPGGA
HHCCCCCCHHHEEECCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCHH
LIEMMASQGCEESYPFSAAKVPGYDLSFSGLKTAVLYAIKGNNSNSRSPLPDLSQKEKNN
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHH
IAASFQKAAFMTIAQKLPKIIKNFSCRSILVGGGVANNKYFQTLLQNTLNLPLYFPSSKL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCC
CTDNAAMIAGLGRELFLSRKTTQGITPCARYRWESVADSLSPHP
CCCCHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA