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The map label for this gene is iorA [H]

Identifier: 89056658

GI number: 89056658

Start: 4275956

End: 4276414

Strand: Direct

Name: iorA [H]

Synonym: Jann_4167

Alternate gene names: 89056658

Gene position: 4275956-4276414 (Clockwise)

Preceding gene: 89056657

Following gene: 89056659

Centisome position: 99.03

GC content: 63.62

Gene sequence:

>459_bases
ATGCGACTGACGGTGAATGGCGAGGAGCGGGAGGTTGACGTTGCCCCCGACATGCCCCTTCTGTGGGTGCTGCGAGAAGA
ATTGAACCTGCCGGGCACGCGCTATGGCTGCGGTATCGCGCAATGCGGAGCGTGCACCGTGCACATTGACGGCCAAGCCG
CGCGGTCCTGCCAGACCCGCGTGGGCGATCTGGACGGGGCTGAGATCACGACGGTTGAGGGCCTCGGCCAACCAGATAGC
CTTCACGCCGTGCAGCAGGCCTGGATCGACCATCAGGTGGCGCAATGCGGTTATTGTCAAAGCGGGCAGATCATGCAGGC
GGCGGCATTGCTGGACGCGAACCCGGCCCCGACCGATCACGACATTGATTTCGTCATGTCCGGCAATCTATGTCGCTGCG
GCACCTATCCGCGCATTCGCGAGGCGATCCATACCGCAGCCCGTGCGATGGAGGGTTGA

Upstream 100 bases:

>100_bases
AGCGGTGATCCTTCACCTAATCAGGTAAGTTATTTGGACAGTAATTGACTATTTGTCTAATTTAGGCAATACATGGGTCC
GTATATCGAGGGAGCCTGCT

Downstream 100 bases:

>100_bases
GTAATGGGCAAGCTGAAAACGTTCACCCGCCGCGCGTTCCTCGTGGGCTCAGCCGCCGTCGCGGGCGGCGTGGCGTTCGG
GACCTATCTGGTGGCCCGCG

Product: (2Fe-2S)-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MRLTVNGEEREVDVAPDMPLLWVLREELNLPGTRYGCGIAQCGACTVHIDGQAARSCQTRVGDLDGAEITTVEGLGQPDS
LHAVQQAWIDHQVAQCGYCQSGQIMQAAALLDANPAPTDHDIDFVMSGNLCRCGTYPRIREAIHTAARAMEG

Sequences:

>Translated_152_residues
MRLTVNGEEREVDVAPDMPLLWVLREELNLPGTRYGCGIAQCGACTVHIDGQAARSCQTRVGDLDGAEITTVEGLGQPDS
LHAVQQAWIDHQVAQCGYCQSGQIMQAAALLDANPAPTDHDIDFVMSGNLCRCGTYPRIREAIHTAARAMEG
>Mature_152_residues
MRLTVNGEEREVDVAPDMPLLWVLREELNLPGTRYGCGIAQCGACTVHIDGQAARSCQTRVGDLDGAEITTVEGLGQPDS
LHAVQQAWIDHQVAQCGYCQSGQIMQAAALLDANPAPTDHDIDFVMSGNLCRCGTYPRIREAIHTAARAMEG

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=156, Percent_Identity=37.1794871794872, Blast_Score=76, Evalue=9e-15,
Organism=Homo sapiens, GI71773480, Length=153, Percent_Identity=36.6013071895425, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1786480, Length=162, Percent_Identity=44.4444444444444, Blast_Score=127, Evalue=3e-31,
Organism=Escherichia coli, GI1789232, Length=143, Percent_Identity=39.1608391608392, Blast_Score=92, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17540638, Length=154, Percent_Identity=42.2077922077922, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=34.4155844155844, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32566215, Length=154, Percent_Identity=35.0649350649351, Blast_Score=96, Evalue=5e-21,
Organism=Drosophila melanogaster, GI17737937, Length=160, Percent_Identity=37.5, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=35.1851851851852, Blast_Score=82, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=35.1851851851852, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24647193, Length=161, Percent_Identity=32.9192546583851, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24647201, Length=154, Percent_Identity=31.1688311688312, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24647199, Length=155, Percent_Identity=30.9677419354839, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16378; Mature: 16378

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
8.6 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
8.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTVNGEEREVDVAPDMPLLWVLREELNLPGTRYGCGIAQCGACTVHIDGQAARSCQTR
CEEECCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHH
VGDLDGAEITTVEGLGQPDSLHAVQQAWIDHQVAQCGYCQSGQIMQAAALLDANPAPTDH
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCC
DIDFVMSGNLCRCGTYPRIREAIHTAARAMEG
CCEEEEECCEEECCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLTVNGEEREVDVAPDMPLLWVLREELNLPGTRYGCGIAQCGACTVHIDGQAARSCQTR
CEEECCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHH
VGDLDGAEITTVEGLGQPDSLHAVQQAWIDHQVAQCGYCQSGQIMQAAALLDANPAPTDH
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCC
DIDFVMSGNLCRCGTYPRIREAIHTAARAMEG
CCEEEEECCEEECCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]