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The map label for this gene is phr [H]

Identifier: 89055300

GI number: 89055300

Start: 2823462

End: 2824673

Strand: Direct

Name: phr [H]

Synonym: Jann_2809

Alternate gene names: 89055300

Gene position: 2823462-2824673 (Clockwise)

Preceding gene: 89055297

Following gene: 89055304

Centisome position: 65.39

GC content: 60.73

Gene sequence:

>1212_bases
ATGAACGCATCACATCCCCCCACCCGCGCGGCCGGACTGGAACGGCTCGCCCGCTTTGTACCCGCTGCCGGGCGCGATTA
TGCCGCCAAACGCAACTACGACTTGCCGGGCCAGGGGCATCCACACGTCTCGCAACTCTCCCCCTACTTGCGCCACCGGC
TGGTCACTGAAGAAGAAGTTCTAGAGGCCGTTCTGGAGCGCTATTCCCTTGCCAACGCTGAGAAATTTGTGGCTGAGGTC
TGCTGGCGAACCTATTGGAAGGGCTGGCTGGAACTGCGACCTTCGGCCTGGGCGGAGTATCGGCGCGACCTTGATCACAT
CGACCGGACAGGCGTCGCCAAGGCGGAGGCGGGTCAGACTGACATCGACGCCTTCAACGCATGGACCCGGGAATTGGTCG
AGACCGGCTATTTGCACAATCACGCCCGCATGTGGTTCGCCTCCATCTGGATCTTTACGCTTGGTTTACCCTGGCAGGCG
GGCGCGGATTTCTTCATGCGTCATCTGCTGGATGGGGATCCGGCCTCCAACACACTTAGCTGGCGCTGGGTCGCGGGGCT
GCAAACCCATGGAAAGCACTATGTTGCCCGCTCATCGAACATCTCGAAATACACGGATGGGCGTCACAATCCTGAATGGC
GTTTGAACACGCAGGCTGAACCTCTCTCCGGCCCGCCTCATCCCGTGCCACGCGCGGCGCCTGTTTCGGACGAGGTGCAA
CCGGGTCTGGCGACCGCTATTTTGCTGCATGACGACGATCTCGCACCTGATGCCCTGACCGACCATCTATCTGATAACAT
TGTCGGTTTGGCGGGCCTTCTGTCCGTTCAAAGACGATCTCCGCAGGGGGTAAGTCCTTTGGTGGCAGGGTTCGCGCTCG
GTGCGCTGGACGATGCGGTGGCGCGATGGGGTCAGCGCTTTGGGCAGCCCGGACCAATCATGGACGACGGGCGTCATCTG
GTCGACTGGGCCAAATCCAACGGTATCGAGCAGATCGTCACGCCCTATGCCCCGACCGGGCCCACCTCAAGCGCGCTGCG
GCGGCTGAGACCCCAGTTGGACGAGCATGGAATAGATCTCGTTCAAATCGTCCGCGCCTGGGATCGGGCCGCCTGGTCCC
ATGCCACACACGGTTTCTTCCGGTTCAAAAAGCACATCCCGGACCTCTTATCCCATCTGACACTCGATAGGGATAGGTTG
GAAAACATCTAG

Upstream 100 bases:

>100_bases
TTCTGACTGAGACTATGTCTGGCCATGGGGGGCTGCAAGGGCACCTTCCGTCGAATTCGCGCGGCTTGACCAATCCTTTG
GTCACAATAGCTGACGCGAT

Downstream 100 bases:

>100_bases
TTTTCTGTGGATAAGATAAAAAATTCTGTAGAGAGGCATTCGATTCATAATATTTCGTTTGCCGGAACGGACGATATCGG
GTTGTGGATAACCCGAACTT

Product: deoxyribodipyrimidine photo-lyase family protein

Products: NA

Alternate protein names: DNA photolyase; Photoreactivating enzyme [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MNASHPPTRAAGLERLARFVPAAGRDYAAKRNYDLPGQGHPHVSQLSPYLRHRLVTEEEVLEAVLERYSLANAEKFVAEV
CWRTYWKGWLELRPSAWAEYRRDLDHIDRTGVAKAEAGQTDIDAFNAWTRELVETGYLHNHARMWFASIWIFTLGLPWQA
GADFFMRHLLDGDPASNTLSWRWVAGLQTHGKHYVARSSNISKYTDGRHNPEWRLNTQAEPLSGPPHPVPRAAPVSDEVQ
PGLATAILLHDDDLAPDALTDHLSDNIVGLAGLLSVQRRSPQGVSPLVAGFALGALDDAVARWGQRFGQPGPIMDDGRHL
VDWAKSNGIEQIVTPYAPTGPTSSALRRLRPQLDEHGIDLVQIVRAWDRAAWSHATHGFFRFKKHIPDLLSHLTLDRDRL
ENI

Sequences:

>Translated_403_residues
MNASHPPTRAAGLERLARFVPAAGRDYAAKRNYDLPGQGHPHVSQLSPYLRHRLVTEEEVLEAVLERYSLANAEKFVAEV
CWRTYWKGWLELRPSAWAEYRRDLDHIDRTGVAKAEAGQTDIDAFNAWTRELVETGYLHNHARMWFASIWIFTLGLPWQA
GADFFMRHLLDGDPASNTLSWRWVAGLQTHGKHYVARSSNISKYTDGRHNPEWRLNTQAEPLSGPPHPVPRAAPVSDEVQ
PGLATAILLHDDDLAPDALTDHLSDNIVGLAGLLSVQRRSPQGVSPLVAGFALGALDDAVARWGQRFGQPGPIMDDGRHL
VDWAKSNGIEQIVTPYAPTGPTSSALRRLRPQLDEHGIDLVQIVRAWDRAAWSHATHGFFRFKKHIPDLLSHLTLDRDRL
ENI
>Mature_403_residues
MNASHPPTRAAGLERLARFVPAAGRDYAAKRNYDLPGQGHPHVSQLSPYLRHRLVTEEEVLEAVLERYSLANAEKFVAEV
CWRTYWKGWLELRPSAWAEYRRDLDHIDRTGVAKAEAGQTDIDAFNAWTRELVETGYLHNHARMWFASIWIFTLGLPWQA
GADFFMRHLLDGDPASNTLSWRWVAGLQTHGKHYVARSSNISKYTDGRHNPEWRLNTQAEPLSGPPHPVPRAAPVSDEVQ
PGLATAILLHDDDLAPDALTDHLSDNIVGLAGLLSVQRRSPQGVSPLVAGFALGALDDAVARWGQRFGQPGPIMDDGRHL
VDWAKSNGIEQIVTPYAPTGPTSSALRRLRPQLDEHGIDLVQIVRAWDRAAWSHATHGFFRFKKHIPDLLSHLTLDRDRL
ENI

Specific function: Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ul

COG id: COG0415

COG function: function code L; Deoxyribodipyrimidine photolyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DNA photolyase domain [H]

Homologues:

Organism=Escherichia coli, GI1786926, Length=209, Percent_Identity=26.7942583732057, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002081
- InterPro:   IPR018394
- InterPro:   IPR006050
- InterPro:   IPR005101
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00875 DNA_photolyase; PF03441 FAD_binding_7 [H]

EC number: =4.1.99.3 [H]

Molecular weight: Translated: 45224; Mature: 45224

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASHPPTRAAGLERLARFVPAAGRDYAAKRNYDLPGQGHPHVSQLSPYLRHRLVTEEEV
CCCCCCCHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHH
LEAVLERYSLANAEKFVAEVCWRTYWKGWLELRPSAWAEYRRDLDHIDRTGVAKAEAGQT
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
DIDAFNAWTRELVETGYLHNHARMWFASIWIFTLGLPWQAGADFFMRHLLDGDPASNTLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCEE
WRWVAGLQTHGKHYVARSSNISKYTDGRHNPEWRLNTQAEPLSGPPHPVPRAAPVSDEVQ
EEEECCHHHCCCEEEECCCCCCHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC
PGLATAILLHDDDLAPDALTDHLSDNIVGLAGLLSVQRRSPQGVSPLVAGFALGALDDAV
CCCEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
ARWGQRFGQPGPIMDDGRHLVDWAKSNGIEQIVTPYAPTGPTSSALRRLRPQLDEHGIDL
HHHHHHCCCCCCCCCCCHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHH
VQIVRAWDRAAWSHATHGFFRFKKHIPDLLSHLTLDRDRLENI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
>Mature Secondary Structure
MNASHPPTRAAGLERLARFVPAAGRDYAAKRNYDLPGQGHPHVSQLSPYLRHRLVTEEEV
CCCCCCCHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHH
LEAVLERYSLANAEKFVAEVCWRTYWKGWLELRPSAWAEYRRDLDHIDRTGVAKAEAGQT
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
DIDAFNAWTRELVETGYLHNHARMWFASIWIFTLGLPWQAGADFFMRHLLDGDPASNTLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCEE
WRWVAGLQTHGKHYVARSSNISKYTDGRHNPEWRLNTQAEPLSGPPHPVPRAAPVSDEVQ
EEEECCHHHCCCEEEECCCCCCHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC
PGLATAILLHDDDLAPDALTDHLSDNIVGLAGLLSVQRRSPQGVSPLVAGFALGALDDAV
CCCEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
ARWGQRFGQPGPIMDDGRHLVDWAKSNGIEQIVTPYAPTGPTSSALRRLRPQLDEHGIDL
HHHHHHCCCCCCCCCCCHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHH
VQIVRAWDRAAWSHATHGFFRFKKHIPDLLSHLTLDRDRLENI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2501760 [H]