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The map label for this gene is mmgC [H]

Identifier: 89055304

GI number: 89055304

Start: 2828122

End: 2829336

Strand: Direct

Name: mmgC [H]

Synonym: Jann_2813

Alternate gene names: 89055304

Gene position: 2828122-2829336 (Clockwise)

Preceding gene: 89055300

Following gene: 89055306

Centisome position: 65.5

GC content: 61.56

Gene sequence:

>1215_bases
ATGCCCGACGGTCAGACACGCCACACCGGTCCTTCGCTTGCGCCTTTCGACTGGGCCGACCCTTTCCATCTGGCAGATCA
GCTGTCTGACGAAGAACGTATGATCGCCGAAAGCGCGCGCGCCTACGCCCAAGACAAGCTGCTGCCCCGCGTCACGGACG
CGTATCTGGAGGAGCATGTGACACCGGACGTCTTTGCCGAAATGGGCGAGATGGGATTGTTGGGAATTACCATTCCCGAA
CATCTGGGCGGTCTGGGGGCGGGCTACGTCAGCTATGGACTCGTCGCGCGCGAGGTGGAGCGGGTGGACAGCGGATATCG
CTCCATGATGTCCGTGCAATCGTCCTTGGTGATGTATCCGATCAATGCCTATGGTTCTGATGAGCAAAGACAAAAATATC
TGCCCGGCCTGGCGGCAGGCACAAAGATCGGCTGCTTCGGACTGACCGAGCCTGACGCAGGATCCGACCCGGCGGGCATG
AAGACCACGGCCAAAAAGACTGAGGGCGGCTATGTGATCAACGGCGCGAAGATGTGGATTTCCAACGCGCCCATTGCTGA
TGTGTTCGTCATCTGGGCCAAATCCGATGCCCATGGCGGCAAGATCCGGGGCTTTGTGCTGGAAAAGGGCATGAAAGGCC
TCTCTGCGCCCAAAATCGGCGGCAAACTCAGCCTGCGCGCCTCGGTCACGGGCGAAATCGTGATGGACAATGTCGAGGTC
GGCGAAGACGCGCTTCTACCCGGTGTCGAAGGCCTGAAAGGGCCGTTTGGCTGTTTGAACCGCGCCCGCTTCGGCATCTC
CTGGGGGGTGATGGGTGCGGCCGAGGATTGCTGGCACCGGGCCCGCGACTATGGTCTTGACCGCGTGCAATTCGGCCGGC
CTTTGGCGCAGACGCAGCTCTTTCAGAAGAAGCTGGCGGACATGCAGACCGAGATCGCCCTCGGCCTCCAGGGCGCCCTG
CGCGCGGGGCGGATGATGGAGGACGGGACCTGCGGGCCGGAGCTTATCTCTTTGATGAAGCGCAACAATTGCGGCAAAGC
GCTGGAGATCGCCCGCCATGCGCGCGACATGCATGGCGGCAACGGGATCATGGCGGAATACCACGTCATGCGTCACGCCC
AGAACCTGGAAACCGTCAACACCTACGAGGGCACGCATGATGTGCATGCCCTCATTCTGGGGCGCGCCCAGACCGGGCTG
CAGGCCTTTTTCTGA

Upstream 100 bases:

>100_bases
GGCCGCCCGGCCTCGGCAAGACGAACGCACCGTCACGCATGTGGCCCCGCGCCTTGCCAAGCGCCCACTGACAGTCAAAT
ATATGCAAAAGGAGATTTCC

Downstream 100 bases:

>100_bases
CGGGTCAGGAGGCCCTGGTCACCGGGAGCTCACCGCCATTCACCTCGTCCGGGCCAGCAGGCTCGGTCGCCGGGGCGGGC
AGCGCCAACGCCTCGTCGGC

Product: acyl-CoA dehydrogenase-like protein

Products: crotonoyl-CoA; CO2; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MPDGQTRHTGPSLAPFDWADPFHLADQLSDEERMIAESARAYAQDKLLPRVTDAYLEEHVTPDVFAEMGEMGLLGITIPE
HLGGLGAGYVSYGLVAREVERVDSGYRSMMSVQSSLVMYPINAYGSDEQRQKYLPGLAAGTKIGCFGLTEPDAGSDPAGM
KTTAKKTEGGYVINGAKMWISNAPIADVFVIWAKSDAHGGKIRGFVLEKGMKGLSAPKIGGKLSLRASVTGEIVMDNVEV
GEDALLPGVEGLKGPFGCLNRARFGISWGVMGAAEDCWHRARDYGLDRVQFGRPLAQTQLFQKKLADMQTEIALGLQGAL
RAGRMMEDGTCGPELISLMKRNNCGKALEIARHARDMHGGNGIMAEYHVMRHAQNLETVNTYEGTHDVHALILGRAQTGL
QAFF

Sequences:

>Translated_404_residues
MPDGQTRHTGPSLAPFDWADPFHLADQLSDEERMIAESARAYAQDKLLPRVTDAYLEEHVTPDVFAEMGEMGLLGITIPE
HLGGLGAGYVSYGLVAREVERVDSGYRSMMSVQSSLVMYPINAYGSDEQRQKYLPGLAAGTKIGCFGLTEPDAGSDPAGM
KTTAKKTEGGYVINGAKMWISNAPIADVFVIWAKSDAHGGKIRGFVLEKGMKGLSAPKIGGKLSLRASVTGEIVMDNVEV
GEDALLPGVEGLKGPFGCLNRARFGISWGVMGAAEDCWHRARDYGLDRVQFGRPLAQTQLFQKKLADMQTEIALGLQGAL
RAGRMMEDGTCGPELISLMKRNNCGKALEIARHARDMHGGNGIMAEYHVMRHAQNLETVNTYEGTHDVHALILGRAQTGL
QAFF
>Mature_403_residues
PDGQTRHTGPSLAPFDWADPFHLADQLSDEERMIAESARAYAQDKLLPRVTDAYLEEHVTPDVFAEMGEMGLLGITIPEH
LGGLGAGYVSYGLVAREVERVDSGYRSMMSVQSSLVMYPINAYGSDEQRQKYLPGLAAGTKIGCFGLTEPDAGSDPAGMK
TTAKKTEGGYVINGAKMWISNAPIADVFVIWAKSDAHGGKIRGFVLEKGMKGLSAPKIGGKLSLRASVTGEIVMDNVEVG
EDALLPGVEGLKGPFGCLNRARFGISWGVMGAAEDCWHRARDYGLDRVQFGRPLAQTQLFQKKLADMQTEIALGLQGALR
AGRMMEDGTCGPELISLMKRNNCGKALEIARHARDMHGGNGIMAEYHVMRHAQNLETVNTYEGTHDVHALILGRAQTGLQ
AFF

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4503943, Length=401, Percent_Identity=60.8478802992519, Blast_Score=502, Evalue=1e-142,
Organism=Homo sapiens, GI7669494, Length=381, Percent_Identity=59.5800524934383, Blast_Score=467, Evalue=1e-131,
Organism=Homo sapiens, GI4557233, Length=402, Percent_Identity=31.3432835820896, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI4501859, Length=365, Percent_Identity=31.7808219178082, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI226958412, Length=393, Percent_Identity=30.0254452926209, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI226958414, Length=368, Percent_Identity=31.7934782608696, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI4501857, Length=375, Percent_Identity=29.3333333333333, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI187960098, Length=377, Percent_Identity=30.2387267904509, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI4557231, Length=377, Percent_Identity=30.2387267904509, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI4557235, Length=384, Percent_Identity=29.4270833333333, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI76496475, Length=384, Percent_Identity=29.4270833333333, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI21361497, Length=358, Percent_Identity=29.8882681564246, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI7656849, Length=379, Percent_Identity=27.9683377308707, Blast_Score=142, Evalue=4e-34,
Organism=Escherichia coli, GI1786223, Length=388, Percent_Identity=26.2886597938144, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87081958, Length=341, Percent_Identity=26.3929618768328, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17534353, Length=393, Percent_Identity=63.1043256997455, Blast_Score=514, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI17538396, Length=376, Percent_Identity=33.2446808510638, Blast_Score=180, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI17508101, Length=366, Percent_Identity=32.7868852459016, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=30.4109589041096, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI71990804, Length=274, Percent_Identity=36.8613138686131, Blast_Score=167, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI71985184, Length=370, Percent_Identity=31.6216216216216, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71985192, Length=304, Percent_Identity=31.9078947368421, Blast_Score=147, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI17534899, Length=380, Percent_Identity=27.8947368421053, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17569725, Length=380, Percent_Identity=27.1052631578947, Blast_Score=144, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=34.3478260869565, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17570075, Length=377, Percent_Identity=27.5862068965517, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71982178, Length=271, Percent_Identity=28.0442804428044, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17533517, Length=373, Percent_Identity=26.5415549597855, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17551932, Length=250, Percent_Identity=26.4, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17505929, Length=354, Percent_Identity=24.8587570621469, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562446, Length=255, Percent_Identity=29.0196078431373, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI19920834, Length=392, Percent_Identity=57.9081632653061, Blast_Score=448, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24666513, Length=371, Percent_Identity=32.8840970350404, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21356377, Length=373, Percent_Identity=29.7587131367292, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24646207, Length=373, Percent_Identity=30.5630026809651, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24660351, Length=379, Percent_Identity=30.0791556728232, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI281363737, Length=343, Percent_Identity=30.3206997084548, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI21355753, Length=378, Percent_Identity=28.3068783068783, Blast_Score=149, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.7

Molecular weight: Translated: 43732; Mature: 43600

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDGQTRHTGPSLAPFDWADPFHLADQLSDEERMIAESARAYAQDKLLPRVTDAYLEEHV
CCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
TPDVFAEMGEMGLLGITIPEHLGGLGAGYVSYGLVAREVERVDSGYRSMMSVQSSLVMYP
CHHHHHHHCCCCEEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEE
INAYGSDEQRQKYLPGLAAGTKIGCFGLTEPDAGSDPAGMKTTAKKTEGGYVINGAKMWI
CCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCEEEE
SNAPIADVFVIWAKSDAHGGKIRGFVLEKGMKGLSAPKIGGKLSLRASVTGEIVMDNVEV
CCCCCEEEEEEEECCCCCCCCEEHHHHHHCCCCCCCCCCCCEEEEEEECCCEEEECCCCC
GEDALLPGVEGLKGPFGCLNRARFGISWGVMGAAEDCWHRARDYGLDRVQFGRPLAQTQL
CCHHCCCCCHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCHHHHHH
FQKKLADMQTEIALGLQGALRAGRMMEDGTCGPELISLMKRNNCGKALEIARHARDMHGG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCC
NGIMAEYHVMRHAQNLETVNTYEGTHDVHALILGRAQTGLQAFF
CCCHHHHHHHHHHHCCCCCCCCCCCHHEEHHEEHHHHHHHHHCC
>Mature Secondary Structure 
PDGQTRHTGPSLAPFDWADPFHLADQLSDEERMIAESARAYAQDKLLPRVTDAYLEEHV
CCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
TPDVFAEMGEMGLLGITIPEHLGGLGAGYVSYGLVAREVERVDSGYRSMMSVQSSLVMYP
CHHHHHHHCCCCEEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEE
INAYGSDEQRQKYLPGLAAGTKIGCFGLTEPDAGSDPAGMKTTAKKTEGGYVINGAKMWI
CCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCEEEE
SNAPIADVFVIWAKSDAHGGKIRGFVLEKGMKGLSAPKIGGKLSLRASVTGEIVMDNVEV
CCCCCEEEEEEEECCCCCCCCEEHHHHHHCCCCCCCCCCCCEEEEEEECCCEEEECCCCC
GEDALLPGVEGLKGPFGCLNRARFGISWGVMGAAEDCWHRARDYGLDRVQFGRPLAQTQL
CCHHCCCCCHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCHHHHHH
FQKKLADMQTEIALGLQGALRAGRMMEDGTCGPELISLMKRNNCGKALEIARHARDMHGG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCC
NGIMAEYHVMRHAQNLETVNTYEGTHDVHALILGRAQTGLQAFF
CCCHHHHHHHHHHHCCCCCCCCCCCHHEEHHEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutaryl-CoA; acceptor

Specific reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]