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The map label for this gene is ynfJ [C]

Identifier: 89055237

GI number: 89055237

Start: 2759721

End: 2761352

Strand: Reverse

Name: ynfJ [C]

Synonym: Jann_2746

Alternate gene names: 89055237

Gene position: 2761352-2759721 (Counterclockwise)

Preceding gene: 89055238

Following gene: 89055236

Centisome position: 63.95

GC content: 63.54

Gene sequence:

>1632_bases
ATGCGCGGGGGCTGGTCCCTTCTGCTGGAGAAGGGGCCGAGCCAGTTCCAGTTCTGGCTGATCGCGTTGTTTATCGGCGT
GGCAGCAGGCTTCACAGCATTGGGATTCCGCAAGGGGGTCAGCTGGTTGCAGGAAACGCTTTATGGTGTCGACGACGTCC
GGATGTTGCACAGCTTCGCCGAAAGCCTGCCGTGGTGGATGATCCTGATCATCCCCATCGGGGGCGGGCTGGTCGTGGGC
GCGATCTTGCACAAGTTCACACCCGATGGGCGCGTGCGATCGGTTGCGGATGTCATCGAAGGCGCGGCCCTGAATGAGGG
GCGGGTTGAAGGACGGGCGGGCCTCGCCTCGGCGCTGGCCTCCCTGATTACCCTCGGTTCGGGTGGCTCGACGGGACGCG
AAGGGCCGGTCGTGCATCTGGCGGCCGTGATCTCATCGAAGATCTCCCGCTGGATCAACGCCGACGGTATTACCGGCCGG
GACCTTTTGGGATGTGCCGTGGCGGCGGCCGTCTCTGCCAGTTTCAACGCACCGATTGCGGGCGCGATCTTCGCCCTTGA
GGTCGTGCTGCGCCACTTCGCCGTGCACGCCTTCGCCCCCATCGTCATCGCCAGCGCCGCGGGGACTGTCATCAACCGGC
TGGAATTTGGCGACGTCACCGAATTCGCGCTGTCCGGCGATGGGATGCTGCGCTTCTACGTGGAACTTCCCGCCTTCCTG
ATTCTTGGCATCCTGTGTGGTTTTGTTGCGGTCCTGTTCATGCGTGGCACCTTCTGGGCAGAGGACCTGGGCACATCGCT
ACAGAACCGCATTAAGCTGCCGCGCTACCTGCGCCCCGCTGTTGCCGGTGTGCTTCTGGGCAGCCTCGCGATCTTTTTTC
CGCATATCATCGGGGTCGGCTATGAGACGACCTCTGCAGCCCTCACGGGGGAACTTTTGCTTTGGGAGGCGATCATCTTC
GCGATCCTCAAGGCTGTCGCGACTGCAATCACTGTCGCGGGACGGATGGGGGGCGGGGTGTTCTCCCCATCGTTGATGAT
TGGCGCGATCACCGGTCTGGCGTTTGGCCTGGTGGCCACGGGGATCTTCCCGGACGTTTCAGGCTCCGAGACGCTCTATG
CGCTTGCGGGCATGGGGGCCGTTGCGGCGGCGGTTCTGGGCGCGCCGATCTCCACCACGCTGATCGTGTTTGAGCTGACC
GGCGACTGGCAGACAGGCCTGGCGGTGATGGTGGCCGTGTCGATGTCTACCGCGATCTCATCCAAAATGGTGCACCGGAG
CTTCTTCCTGACGCAATTGGAACGGCGGAACATCCACCTGGCCGCGGGGCCGCAGGCCTACCTTCTGGCGATGTTCCGGG
TGGGGCGGGTGATGCGACCGATGACCCACGAGGACTCGGCGCCGGAGGAGCGGCTTCTGACCCTGATCGAGCAGGGAATT
TTCACCGACACCAATGCCACGCTGGAACGGGCCTTGCCGATATTCGAGCGGACGGGGTTGGATTTCGTACCTGTCGTGCA
ACTCTCACCCTCCGGTGGCCCGCCAGCGCTGGAGGGGGCATTGTTCCATGTTGACGCGCTGAAGGCCTACAACAAGGCTC
TGGCCGCGACGGCAGCGGAGGAACACAGCTAA

Upstream 100 bases:

>100_bases
AACCGTTGCCCCGAGCCCGCGTGCCAGAAAGTGAGCCCCTCCCGTGGCATTTGATCCGCGCGGTTTCATCCAACACCAAG
CCCACCGGGCCGCTTTGGGG

Downstream 100 bases:

>100_bases
TTTGTGTCCGCTGCGGCCAGAAACGCAGAAATTTTCTTTGGCGAAAGCGGCTTGGAGCGGCATTGTTAACCCCATGATAC
TAAGGATTCTCTCAGCTCTC

Product: Cl- channel, voltage gated

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 543; Mature: 543

Protein sequence:

>543_residues
MRGGWSLLLEKGPSQFQFWLIALFIGVAAGFTALGFRKGVSWLQETLYGVDDVRMLHSFAESLPWWMILIIPIGGGLVVG
AILHKFTPDGRVRSVADVIEGAALNEGRVEGRAGLASALASLITLGSGGSTGREGPVVHLAAVISSKISRWINADGITGR
DLLGCAVAAAVSASFNAPIAGAIFALEVVLRHFAVHAFAPIVIASAAGTVINRLEFGDVTEFALSGDGMLRFYVELPAFL
ILGILCGFVAVLFMRGTFWAEDLGTSLQNRIKLPRYLRPAVAGVLLGSLAIFFPHIIGVGYETTSAALTGELLLWEAIIF
AILKAVATAITVAGRMGGGVFSPSLMIGAITGLAFGLVATGIFPDVSGSETLYALAGMGAVAAAVLGAPISTTLIVFELT
GDWQTGLAVMVAVSMSTAISSKMVHRSFFLTQLERRNIHLAAGPQAYLLAMFRVGRVMRPMTHEDSAPEERLLTLIEQGI
FTDTNATLERALPIFERTGLDFVPVVQLSPSGGPPALEGALFHVDALKAYNKALAATAAEEHS

Sequences:

>Translated_543_residues
MRGGWSLLLEKGPSQFQFWLIALFIGVAAGFTALGFRKGVSWLQETLYGVDDVRMLHSFAESLPWWMILIIPIGGGLVVG
AILHKFTPDGRVRSVADVIEGAALNEGRVEGRAGLASALASLITLGSGGSTGREGPVVHLAAVISSKISRWINADGITGR
DLLGCAVAAAVSASFNAPIAGAIFALEVVLRHFAVHAFAPIVIASAAGTVINRLEFGDVTEFALSGDGMLRFYVELPAFL
ILGILCGFVAVLFMRGTFWAEDLGTSLQNRIKLPRYLRPAVAGVLLGSLAIFFPHIIGVGYETTSAALTGELLLWEAIIF
AILKAVATAITVAGRMGGGVFSPSLMIGAITGLAFGLVATGIFPDVSGSETLYALAGMGAVAAAVLGAPISTTLIVFELT
GDWQTGLAVMVAVSMSTAISSKMVHRSFFLTQLERRNIHLAAGPQAYLLAMFRVGRVMRPMTHEDSAPEERLLTLIEQGI
FTDTNATLERALPIFERTGLDFVPVVQLSPSGGPPALEGALFHVDALKAYNKALAATAAEEHS
>Mature_543_residues
MRGGWSLLLEKGPSQFQFWLIALFIGVAAGFTALGFRKGVSWLQETLYGVDDVRMLHSFAESLPWWMILIIPIGGGLVVG
AILHKFTPDGRVRSVADVIEGAALNEGRVEGRAGLASALASLITLGSGGSTGREGPVVHLAAVISSKISRWINADGITGR
DLLGCAVAAAVSASFNAPIAGAIFALEVVLRHFAVHAFAPIVIASAAGTVINRLEFGDVTEFALSGDGMLRFYVELPAFL
ILGILCGFVAVLFMRGTFWAEDLGTSLQNRIKLPRYLRPAVAGVLLGSLAIFFPHIIGVGYETTSAALTGELLLWEAIIF
AILKAVATAITVAGRMGGGVFSPSLMIGAITGLAFGLVATGIFPDVSGSETLYALAGMGAVAAAVLGAPISTTLIVFELT
GDWQTGLAVMVAVSMSTAISSKMVHRSFFLTQLERRNIHLAAGPQAYLLAMFRVGRVMRPMTHEDSAPEERLLTLIEQGI
FTDTNATLERALPIFERTGLDFVPVVQLSPSGGPPALEGALFHVDALKAYNKALAATAAEEHS

Specific function: Unknown

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Homo sapiens, GI156104869, Length=365, Percent_Identity=26.5753424657534, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI283806622, Length=365, Percent_Identity=26.5753424657534, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI283806618, Length=365, Percent_Identity=26.5753424657534, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI87081943, Length=433, Percent_Identity=30.4849884526559, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1786350, Length=410, Percent_Identity=26.5853658536585, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71980824, Length=466, Percent_Identity=23.3905579399142, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71980828, Length=466, Percent_Identity=23.3905579399142, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17532615, Length=589, Percent_Identity=24.7877758913413, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71980820, Length=471, Percent_Identity=23.3545647558386, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 57189; Mature: 57189

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGGWSLLLEKGPSQFQFWLIALFIGVAAGFTALGFRKGVSWLQETLYGVDDVRMLHSFA
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
ESLPWWMILIIPIGGGLVVGAILHKFTPDGRVRSVADVIEGAALNEGRVEGRAGLASALA
HHCCEEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
SLITLGSGGSTGREGPVVHLAAVISSKISRWINADGITGRDLLGCAVAAAVSASFNAPIA
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHH
GAIFALEVVLRHFAVHAFAPIVIASAAGTVINRLEFGDVTEFALSGDGMLRFYVELPAFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEHHHHHHHHH
ILGILCGFVAVLFMRGTFWAEDLGTSLQNRIKLPRYLRPAVAGVLLGSLAIFFPHIIGVG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
YETTSAALTGELLLWEAIIFAILKAVATAITVAGRMGGGVFSPSLMIGAITGLAFGLVAT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
GIFPDVSGSETLYALAGMGAVAAAVLGAPISTTLIVFELTGDWQTGLAVMVAVSMSTAIS
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHH
SKMVHRSFFLTQLERRNIHLAAGPQAYLLAMFRVGRVMRPMTHEDSAPEERLLTLIEQGI
HHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
FTDTNATLERALPIFERTGLDFVPVVQLSPSGGPPALEGALFHVDALKAYNKALAATAAE
CCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EHS
CCC
>Mature Secondary Structure
MRGGWSLLLEKGPSQFQFWLIALFIGVAAGFTALGFRKGVSWLQETLYGVDDVRMLHSFA
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
ESLPWWMILIIPIGGGLVVGAILHKFTPDGRVRSVADVIEGAALNEGRVEGRAGLASALA
HHCCEEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
SLITLGSGGSTGREGPVVHLAAVISSKISRWINADGITGRDLLGCAVAAAVSASFNAPIA
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHH
GAIFALEVVLRHFAVHAFAPIVIASAAGTVINRLEFGDVTEFALSGDGMLRFYVELPAFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEHHHHHHHHH
ILGILCGFVAVLFMRGTFWAEDLGTSLQNRIKLPRYLRPAVAGVLLGSLAIFFPHIIGVG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
YETTSAALTGELLLWEAIIFAILKAVATAITVAGRMGGGVFSPSLMIGAITGLAFGLVAT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
GIFPDVSGSETLYALAGMGAVAAAVLGAPISTTLIVFELTGDWQTGLAVMVAVSMSTAIS
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHH
SKMVHRSFFLTQLERRNIHLAAGPQAYLLAMFRVGRVMRPMTHEDSAPEERLLTLIEQGI
HHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
FTDTNATLERALPIFERTGLDFVPVVQLSPSGGPPALEGALFHVDALKAYNKALAATAAE
CCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EHS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]