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The map label for this gene is dhaAF [H]

Identifier: 89055111

GI number: 89055111

Start: 2639235

End: 2640227

Strand: Direct

Name: dhaAF [H]

Synonym: Jann_2620

Alternate gene names: 89055111

Gene position: 2639235-2640227 (Clockwise)

Preceding gene: 89055110

Following gene: 89055112

Centisome position: 61.12

GC content: 60.22

Gene sequence:

>993_bases
ATGAAACGAATACGAGCGCTGGCGACAGCCGCAACACTGGCTGCGGGCCTCGCCATGCCTGTAGCGGCGCAGGACACAGG
TGGTGCGCAACAACCGATCTCTGCCGAATTCCCGTTTGAGCTTCAGACCGTCGAAGTATTGGGGTCGAACATGGCTTACG
TCGATACAGGCGACGGCCCGGTTGTTTTGTTCATTCACGGCAACCCGACATCGTCTTACCTGTGGCGCAATGTGATACCG
CATGTGGCGGAGGATCACCGCGCGATTGCCATCGACCTGATCGGCATGGGAGCCAGCGACAAGCCTGACATCGATTATAC
GTTTCAGGATCATTACGCGCATCTTGAAGGGTTCATCGACGCGCTGGAGCTGACGGATATCACCCTTGTCCTGCACGATT
GGGGCGGCGGGCTTGGCACTTATTACGCGGCCAACAACTCCGACAATGTCCGCGCCATTGCGATGATGGAGGCGGCAGCC
CCGCCCGCTTTGCCGATCCCCGATTGGGCGATGGTCGCGGACCAGCAGACCCGTGAGACGTTTCAGGCCTTCCGTGACCC
TGTGATGGGCCCCCAGATCATCCTTGAACAGAACGGTTTTGTCGAAGGGCTGCTGCCCGCCACGATCCTGCGCACGCTGA
GCGATGCCGAGATGGACGCCTACCGCGCGCCTTTTCCCACACCCGAAAGCCGCCAACCTGTTCTGATGTGGCCCAACGAA
ATCCCGATCGAAGGCACGCCCGCGCGCAATGTCACTGTGATGGAAGAGGTGGCGGCATGGCTAACCACATCCGAGCAGCC
CAAATTGATCCTTTATGCCTCGCCCGGCTTGATCTGGTCGCCTGAGGTTGCCGATTTCGCCGCCCGCACCTTCAACAACA
CCGAGGCCCGTTTCGTCGGGGCTGGCATCCACTTCATCCAGGAAGATCAACCCGAAGCCATCGGTCGCAACCTGTCCGAC
TGGCTGCGCGACCGCGTCACGAGAGGAAACTGA

Upstream 100 bases:

>100_bases
CGTCCGAACAAGGAACTAAACGCGATCGCAGAAAACGCGCTGAAGGACCTGGTCTAAAATTTCACCATAATTCACCAATC
GTTGAAATAAGGAGAACACA

Downstream 100 bases:

>100_bases
ACCATGAGCGATACCAACCCCGTCTACATGATCGTGATGCTCGAAATCGACGATATGCCGACCTTCTTTGAGGATTATGC
CAACCCGTTGCAGGCGATCC

Product: haloalkane dehalogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKRIRALATAATLAAGLAMPVAAQDTGGAQQPISAEFPFELQTVEVLGSNMAYVDTGDGPVVLFIHGNPTSSYLWRNVIP
HVAEDHRAIAIDLIGMGASDKPDIDYTFQDHYAHLEGFIDALELTDITLVLHDWGGGLGTYYAANNSDNVRAIAMMEAAA
PPALPIPDWAMVADQQTRETFQAFRDPVMGPQIILEQNGFVEGLLPATILRTLSDAEMDAYRAPFPTPESRQPVLMWPNE
IPIEGTPARNVTVMEEVAAWLTTSEQPKLILYASPGLIWSPEVADFAARTFNNTEARFVGAGIHFIQEDQPEAIGRNLSD
WLRDRVTRGN

Sequences:

>Translated_330_residues
MKRIRALATAATLAAGLAMPVAAQDTGGAQQPISAEFPFELQTVEVLGSNMAYVDTGDGPVVLFIHGNPTSSYLWRNVIP
HVAEDHRAIAIDLIGMGASDKPDIDYTFQDHYAHLEGFIDALELTDITLVLHDWGGGLGTYYAANNSDNVRAIAMMEAAA
PPALPIPDWAMVADQQTRETFQAFRDPVMGPQIILEQNGFVEGLLPATILRTLSDAEMDAYRAPFPTPESRQPVLMWPNE
IPIEGTPARNVTVMEEVAAWLTTSEQPKLILYASPGLIWSPEVADFAARTFNNTEARFVGAGIHFIQEDQPEAIGRNLSD
WLRDRVTRGN
>Mature_330_residues
MKRIRALATAATLAAGLAMPVAAQDTGGAQQPISAEFPFELQTVEVLGSNMAYVDTGDGPVVLFIHGNPTSSYLWRNVIP
HVAEDHRAIAIDLIGMGASDKPDIDYTFQDHYAHLEGFIDALELTDITLVLHDWGGGLGTYYAANNSDNVRAIAMMEAAA
PPALPIPDWAMVADQQTRETFQAFRDPVMGPQIILEQNGFVEGLLPATILRTLSDAEMDAYRAPFPTPESRQPVLMWPNE
IPIEGTPARNVTVMEEVAAWLTTSEQPKLILYASPGLIWSPEVADFAARTFNNTEARFVGAGIHFIQEDQPEAIGRNLSD
WLRDRVTRGN

Specific function: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Has a broad substrate specificity, which includes mono- and di- chlorinated

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the haloalkane dehalogenase family. Type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=308, Percent_Identity=24.6753246753247, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562298, Length=299, Percent_Identity=22.742474916388, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.5 [H]

Molecular weight: Translated: 36097; Mature: 36097

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIRALATAATLAAGLAMPVAAQDTGGAQQPISAEFPFELQTVEVLGSNMAYVDTGDGP
CCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCC
VVLFIHGNPTSSYLWRNVIPHVAEDHRAIAIDLIGMGASDKPDIDYTFQDHYAHLEGFID
EEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCEEHHHHHHHHHHHHH
ALELTDITLVLHDWGGGLGTYYAANNSDNVRAIAMMEAAAPPALPIPDWAMVADQQTRET
HHHHCEEEEEEEECCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCHHHHCCHHHHHH
FQAFRDPVMGPQIILEQNGFVEGLLPATILRTLSDAEMDAYRAPFPTPESRQPVLMWPNE
HHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCEEECCCC
IPIEGTPARNVTVMEEVAAWLTTSEQPKLILYASPGLIWSPEVADFAARTFNNTEARFVG
CCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCEECCCHHHHHHHHCCCCCCEEEE
AGIHFIQEDQPEAIGRNLSDWLRDRVTRGN
CCEEEECCCCHHHHCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKRIRALATAATLAAGLAMPVAAQDTGGAQQPISAEFPFELQTVEVLGSNMAYVDTGDGP
CCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCC
VVLFIHGNPTSSYLWRNVIPHVAEDHRAIAIDLIGMGASDKPDIDYTFQDHYAHLEGFID
EEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCEEHHHHHHHHHHHHH
ALELTDITLVLHDWGGGLGTYYAANNSDNVRAIAMMEAAAPPALPIPDWAMVADQQTRET
HHHHCEEEEEEEECCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCHHHHCCHHHHHH
FQAFRDPVMGPQIILEQNGFVEGLLPATILRTLSDAEMDAYRAPFPTPESRQPVLMWPNE
HHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCEEECCCC
IPIEGTPARNVTVMEEVAAWLTTSEQPKLILYASPGLIWSPEVADFAARTFNNTEARFVG
CCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCEECCCHHHHHHHHCCCCCCEEEE
AGIHFIQEDQPEAIGRNLSDWLRDRVTRGN
CCEEEECCCCHHHHCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10094681; 10735862 [H]