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The map label for this gene is nuoE [H]

Identifier: 89055051

GI number: 89055051

Start: 2562387

End: 2562890

Strand: Reverse

Name: nuoE [H]

Synonym: Jann_2560

Alternate gene names: 89055051

Gene position: 2562890-2562387 (Counterclockwise)

Preceding gene: 89055052

Following gene: 89055050

Centisome position: 59.35

GC content: 63.29

Gene sequence:

>504_bases
ATGTCAGCCACAGCCGCCCCGCCCAAACCCGATGACCTCCTCGTGGAGGTCGACGCGATCATCCAGAAAAACATAGCTCT
GGAAGGGCCGTTGCTGCCGATCTTGCACGATGTGCAGGCGGCTTTTGGTTACGTGCCTGATGACGCGCGCGCGCTGATTG
CCACCGCGCTCAACATCACCGAAGCGGAATTGCATGGGGTGATTTCCTTTTATCACGACTTCCGCCGCAAGCCTGCGGGC
AAGCGGGTCCTGAAGATTTGCCGGGCCGAGGCCTGTCAGGCGATGGGGGCAAATGCGATGTCGGATGCGGTGCTGGCACA
GCTCGGGCTGGGTTGGGGAGAGACGGCGGCGGATGGCGGTTTGACGGTCGAGCCGATCTATTGCCTGGGCCTGTGTGCCT
GTGGCCCGGCGGCGATGATCGACGGCAAGCTGAAGGGTCGGGTGACCGCGGACAGCCTGATCGCAGAGGTGTCGCCTCAG
CAGGGCGCGGGAGCAATGTCATGA

Upstream 100 bases:

>100_bases
GGCTCGCCATTATCGAGAAACTCAATCGACCAACGAAATTACGATATTGATTTCCGAATGAAGGCGATGCACGCAGGAGG
CGACCAGTTCGGAGCCCGCC

Downstream 100 bases:

>100_bases
GCATCAAGGTCTGGGTGCCCCGCGATGCGGCGGCAAAAGCCCTTGGGGCGGATGAGGTGGCTGCCGCGTTCAAAGCGGCG
GGGGCCGACGTTGTGCGCAA

Product: NADH dehydrogenase (ubiquinone), 24 kDa subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MSATAAPPKPDDLLVEVDAIIQKNIALEGPLLPILHDVQAAFGYVPDDARALIATALNITEAELHGVISFYHDFRRKPAG
KRVLKICRAEACQAMGANAMSDAVLAQLGLGWGETAADGGLTVEPIYCLGLCACGPAAMIDGKLKGRVTADSLIAEVSPQ
QGAGAMS

Sequences:

>Translated_167_residues
MSATAAPPKPDDLLVEVDAIIQKNIALEGPLLPILHDVQAAFGYVPDDARALIATALNITEAELHGVISFYHDFRRKPAG
KRVLKICRAEACQAMGANAMSDAVLAQLGLGWGETAADGGLTVEPIYCLGLCACGPAAMIDGKLKGRVTADSLIAEVSPQ
QGAGAMS
>Mature_166_residues
SATAAPPKPDDLLVEVDAIIQKNIALEGPLLPILHDVQAAFGYVPDDARALIATALNITEAELHGVISFYHDFRRKPAGK
RVLKICRAEACQAMGANAMSDAVLAQLGLGWGETAADGGLTVEPIYCLGLCACGPAAMIDGKLKGRVTADSLIAEVSPQQ
GAGAMS

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=136, Percent_Identity=28.6764705882353, Blast_Score=71, Evalue=4e-13,
Organism=Escherichia coli, GI1788621, Length=116, Percent_Identity=34.4827586206897, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17561328, Length=113, Percent_Identity=32.7433628318584, Blast_Score=76, Evalue=6e-15,
Organism=Drosophila melanogaster, GI18859877, Length=126, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355353, Length=126, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 17310; Mature: 17179

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATAAPPKPDDLLVEVDAIIQKNIALEGPLLPILHDVQAAFGYVPDDARALIATALNIT
CCCCCCCCCCCHHEEHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EAELHGVISFYHDFRRKPAGKRVLKICRAEACQAMGANAMSDAVLAQLGLGWGETAADGG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCC
LTVEPIYCLGLCACGPAAMIDGKLKGRVTADSLIAEVSPQQGAGAMS
CEECHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SATAAPPKPDDLLVEVDAIIQKNIALEGPLLPILHDVQAAFGYVPDDARALIATALNIT
CCCCCCCCCCHHEEHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EAELHGVISFYHDFRRKPAGKRVLKICRAEACQAMGANAMSDAVLAQLGLGWGETAADGG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCC
LTVEPIYCLGLCACGPAAMIDGKLKGRVTADSLIAEVSPQQGAGAMS
CEECHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]