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The map label for this gene is yfeR [H]

Identifier: 89055052

GI number: 89055052

Start: 2563041

End: 2563934

Strand: Reverse

Name: yfeR [H]

Synonym: Jann_2561

Alternate gene names: 89055052

Gene position: 2563934-2563041 (Counterclockwise)

Preceding gene: 89055057

Following gene: 89055051

Centisome position: 59.38

GC content: 63.65

Gene sequence:

>894_bases
ATGATCCATAAGCTCGAAATGTTCATCGCCGTGGCGCGGGAAGCGCACTTTGGTCGAGCGGCGGAAAGCCTTGGCCTGAC
GCAGCCCACATTATCAACTGGAATCAAGCAGTTGGAAGAGATGTTGGGCGTGCAGCTGATCTTTCGGGGCTCTCGCTACG
GCGGCCTCACGCCGGAAGGGCAACGCGCGCTGGTCTGGGCGCGCCAGCTTGTCAGCGACGCGCGGACGTTCCGGCAGGAG
ATGCGCACCGCGCGCCACGGGCTCAGCGGGATCGTGCGCCTTGCCGTCATCCCCACGGCACTCACCTGGGCCGCGCATCT
GAGCGCACGCTTTTCGGCCGCGCACCCCAATGTCCGCTTTTCCATCCTCAGCCGAACGTCCGCAGAGATCCTGTCGATGC
TGGAAAATCTGGAGGCGGATGCGGGGCTCTCCTACCTCGACAATGAACCTCTGGGGCGTGTGACCACGGAACCGCTCTAC
CGCGAACGTCACACCGTCGTGGCCCATCGCGACAGCGATATTGCCATGCAGGACAAGGTCGAATGGGCCGATCTGGCTGG
AGAGCGGTTGTGCCTTCTGACGCCCAACATGCAGAACCGGCGGATCATCAACGAATATTTCATGGCGGCAGGCATCGCGC
CCGAGGCGCAGGTTGAAAGCAATTCCACGGTCGTGCTGGCGGCCCATGTGGAGGCGGGCGACTGGATCACGATCCTGCCC
GTCGACATGGCGCGCTTCTTGTGTGGCGGCAAACCGCATCTGGTCATTCGCGAGATTGAGGGGACGGGCATGGACCACGC
CGTGGGCCTCGTCGCGCCCTATCGGGAGCCCCATACGCCGGTGCTGAACGCCCTGATTTCCGAGACTCGGGCGCTGGCAA
AGGCCCATGCCTGA

Upstream 100 bases:

>100_bases
CGACATTGGTCACCTTATGCGTGCAAGGAACGCGATGATGCCGGACCTTCAATAGAGTTTCTCAATTGATCTATTCGTAA
TTGGTCGCCAAGCTGCACCT

Downstream 100 bases:

>100_bases
GGCCTGACAGGAATAGTCAGGTTTTTCAGGGTGCTAAGGCGCTATGCGCAGGCTCGCCATTATCGAGAAACTCAATCGAC
CAACGAAATTACGATATTGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MIHKLEMFIAVAREAHFGRAAESLGLTQPTLSTGIKQLEEMLGVQLIFRGSRYGGLTPEGQRALVWARQLVSDARTFRQE
MRTARHGLSGIVRLAVIPTALTWAAHLSARFSAAHPNVRFSILSRTSAEILSMLENLEADAGLSYLDNEPLGRVTTEPLY
RERHTVVAHRDSDIAMQDKVEWADLAGERLCLLTPNMQNRRIINEYFMAAGIAPEAQVESNSTVVLAAHVEAGDWITILP
VDMARFLCGGKPHLVIREIEGTGMDHAVGLVAPYREPHTPVLNALISETRALAKAHA

Sequences:

>Translated_297_residues
MIHKLEMFIAVAREAHFGRAAESLGLTQPTLSTGIKQLEEMLGVQLIFRGSRYGGLTPEGQRALVWARQLVSDARTFRQE
MRTARHGLSGIVRLAVIPTALTWAAHLSARFSAAHPNVRFSILSRTSAEILSMLENLEADAGLSYLDNEPLGRVTTEPLY
RERHTVVAHRDSDIAMQDKVEWADLAGERLCLLTPNMQNRRIINEYFMAAGIAPEAQVESNSTVVLAAHVEAGDWITILP
VDMARFLCGGKPHLVIREIEGTGMDHAVGLVAPYREPHTPVLNALISETRALAKAHA
>Mature_297_residues
MIHKLEMFIAVAREAHFGRAAESLGLTQPTLSTGIKQLEEMLGVQLIFRGSRYGGLTPEGQRALVWARQLVSDARTFRQE
MRTARHGLSGIVRLAVIPTALTWAAHLSARFSAAHPNVRFSILSRTSAEILSMLENLEADAGLSYLDNEPLGRVTTEPLY
RERHTVVAHRDSDIAMQDKVEWADLAGERLCLLTPNMQNRRIINEYFMAAGIAPEAQVESNSTVVLAAHVEAGDWITILP
VDMARFLCGGKPHLVIREIEGTGMDHAVGLVAPYREPHTPVLNALISETRALAKAHA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788748, Length=263, Percent_Identity=32.319391634981, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI145693105, Length=242, Percent_Identity=29.7520661157025, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI157672245, Length=247, Percent_Identity=31.5789473684211, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI2367136, Length=237, Percent_Identity=29.957805907173, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790399, Length=240, Percent_Identity=28.3333333333333, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789506, Length=249, Percent_Identity=26.1044176706827, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788296, Length=228, Percent_Identity=23.6842105263158, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786401, Length=194, Percent_Identity=27.8350515463918, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787601, Length=246, Percent_Identity=23.9837398373984, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI87081904, Length=188, Percent_Identity=26.063829787234, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787879, Length=256, Percent_Identity=26.5625, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994962, Length=84, Percent_Identity=45.2380952380952, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787806, Length=252, Percent_Identity=26.984126984127, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32724; Mature: 32724

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHKLEMFIAVAREAHFGRAAESLGLTQPTLSTGIKQLEEMLGVQLIFRGSRYGGLTPEG
CCHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCC
QRALVWARQLVSDARTFRQEMRTARHGLSGIVRLAVIPTALTWAAHLSARFSAAHPNVRF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
SILSRTSAEILSMLENLEADAGLSYLDNEPLGRVTTEPLYRERHTVVAHRDSDIAMQDKV
EEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEEECCCCCCHHHCC
EWADLAGERLCLLTPNMQNRRIINEYFMAAGIAPEAQVESNSTVVLAAHVEAGDWITILP
HHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCEECCCCEEEEEEEECCCCEEEEEH
VDMARFLCGGKPHLVIREIEGTGMDHAVGLVAPYREPHTPVLNALISETRALAKAHA
HHHHHHHHCCCCCEEEEEECCCCCCHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIHKLEMFIAVAREAHFGRAAESLGLTQPTLSTGIKQLEEMLGVQLIFRGSRYGGLTPEG
CCHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCC
QRALVWARQLVSDARTFRQEMRTARHGLSGIVRLAVIPTALTWAAHLSARFSAAHPNVRF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
SILSRTSAEILSMLENLEADAGLSYLDNEPLGRVTTEPLYRERHTVVAHRDSDIAMQDKV
EEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEEECCCCCCHHHCC
EWADLAGERLCLLTPNMQNRRIINEYFMAAGIAPEAQVESNSTVVLAAHVEAGDWITILP
HHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCEECCCCEEEEEEEECCCCEEEEEH
VDMARFLCGGKPHLVIREIEGTGMDHAVGLVAPYREPHTPVLNALISETRALAKAHA
HHHHHHHHCCCCCEEEEEECCCCCCHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]