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The map label for this gene is thiE [H]

Identifier: 89054925

GI number: 89054925

Start: 2428213

End: 2428842

Strand: Direct

Name: thiE [H]

Synonym: Jann_2434

Alternate gene names: 89054925

Gene position: 2428213-2428842 (Clockwise)

Preceding gene: 89054921

Following gene: 89054929

Centisome position: 56.23

GC content: 65.87

Gene sequence:

>630_bases
ATGGACGACGCAACCGCCCCCGAGACCCCGCAACTCTACCTCATCACGCCCACAGCGTTTGAGCCGGAGGTCTTTGCACC
GCACCTGGCGACGGTTCTGGATGCCGTCGACATCGCCTGCATTCGCCTGGCCCTCGTCACGGAGGATGAGGCCGCCCTGT
CACGCGCCGCCGACCAGTGCCGCGATGTGGCCCACGCCCGGGACGTGCCGCTGGTGATCGACCGGCATATCCAATTGGTG
GAGCGGTTGGGCCTTGACGGCGTGCATCTGACCGACGGCGCGCGATCCGTCCGGGACACGCGCAAAGCCCTCGGCGCTGA
CGCCATTATTGGCGCCTATTGCGGGAACTCTCGCCACGACGGCATGTCCGCCGGAGAGGCCGGCGCGGATTATGTCAGCT
TCGGACCTGTGGGTGAGAACGCCCTCGGCGATGGCACCCGCGCGGAGCATGACTTGTTCGCCTGGTGGTCGCAGATGATT
GAAGTGCCCGTCGTGGCCGAAGGCGCTTTGGACGCTGCTCTGGTGGAGACCTTCGCGCCGGTCACAGATTTCTTCGCCAT
CGGGCCGGAGATCTGGCGGCATGACGATCCTCTGGCAGCGTTGCAAGGGGTGACGGCTTCGATCCTGTAG

Upstream 100 bases:

>100_bases
TACCCAGCGGCGCGTGACGGCGCAAGATGTGCGCCGATTGCCTTGGCCGCAAAGGGACGGTATCAGCGCCGCACTGACCC
TTTGCCGCCAGGATCCCCCG

Downstream 100 bases:

>100_bases
GCTGCCCCTTGATGCGTCCGACCGCCGCAGATCGTGTGCGGACGGAACTTTCCCGCGACGCATCACGGTGACGGAAGCGC
CTCCACATCCAGGCCGCCGC

Product: thiamine monophosphate synthase

Products: NA

Alternate protein names: TMP pyrophosphorylase; TMP-PPase; Thiamine-phosphate synthase [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MDDATAPETPQLYLITPTAFEPEVFAPHLATVLDAVDIACIRLALVTEDEAALSRAADQCRDVAHARDVPLVIDRHIQLV
ERLGLDGVHLTDGARSVRDTRKALGADAIIGAYCGNSRHDGMSAGEAGADYVSFGPVGENALGDGTRAEHDLFAWWSQMI
EVPVVAEGALDAALVETFAPVTDFFAIGPEIWRHDDPLAALQGVTASIL

Sequences:

>Translated_209_residues
MDDATAPETPQLYLITPTAFEPEVFAPHLATVLDAVDIACIRLALVTEDEAALSRAADQCRDVAHARDVPLVIDRHIQLV
ERLGLDGVHLTDGARSVRDTRKALGADAIIGAYCGNSRHDGMSAGEAGADYVSFGPVGENALGDGTRAEHDLFAWWSQMI
EVPVVAEGALDAALVETFAPVTDFFAIGPEIWRHDDPLAALQGVTASIL
>Mature_209_residues
MDDATAPETPQLYLITPTAFEPEVFAPHLATVLDAVDIACIRLALVTEDEAALSRAADQCRDVAHARDVPLVIDRHIQLV
ERLGLDGVHLTDGARSVRDTRKALGADAIIGAYCGNSRHDGMSAGEAGADYVSFGPVGENALGDGTRAEHDLFAWWSQMI
EVPVVAEGALDAALVETFAPVTDFFAIGPEIWRHDDPLAALQGVTASIL

Specific function: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) [H]

COG id: COG0352

COG function: function code H; Thiamine monophosphate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TMP-PPase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022998
- InterPro:   IPR003733 [H]

Pfam domain/function: PF02581 TMP-TENI [H]

EC number: =2.5.1.3 [H]

Molecular weight: Translated: 22239; Mature: 22239

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDATAPETPQLYLITPTAFEPEVFAPHLATVLDAVDIACIRLALVTEDEAALSRAADQC
CCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RDVAHARDVPLVIDRHIQLVERLGLDGVHLTDGARSVRDTRKALGADAIIGAYCGNSRHD
HHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCHHHHHHHCCCCCCC
GMSAGEAGADYVSFGPVGENALGDGTRAEHDLFAWWSQMIEVPVVAEGALDAALVETFAP
CCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VTDFFAIGPEIWRHDDPLAALQGVTASIL
HHHHHHHCHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MDDATAPETPQLYLITPTAFEPEVFAPHLATVLDAVDIACIRLALVTEDEAALSRAADQC
CCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RDVAHARDVPLVIDRHIQLVERLGLDGVHLTDGARSVRDTRKALGADAIIGAYCGNSRHD
HHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCHHHHHHHCCCCCCC
GMSAGEAGADYVSFGPVGENALGDGTRAEHDLFAWWSQMIEVPVVAEGALDAALVETFAP
CCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VTDFFAIGPEIWRHDDPLAALQGVTASIL
HHHHHHHCHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA