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The map label for this gene is rbsK [H]

Identifier: 89054600

GI number: 89054600

Start: 2117494

End: 2118342

Strand: Direct

Name: rbsK [H]

Synonym: Jann_2109

Alternate gene names: 89054600

Gene position: 2117494-2118342 (Clockwise)

Preceding gene: 89054599

Following gene: 89054603

Centisome position: 49.04

GC content: 65.14

Gene sequence:

>849_bases
ATGAGCCTGCTCGTTGTCGGTGCGTTGCATTGGGATGTTGTGGTGCAGGCGTCCCGTTTGCCCCGCATCGACGAGACGTT
GCGCGGATCCGGCGTGACGTATCAGTTTGGCGGCAAGGCCGGAAATCAGGCGATCGCGGCGGCAGGGGCCGGGGCGGATG
TCGGTTTTGCTGGCCGCAATGGCACCGACGAGGCGGGCCAGTCCATGCAGGCGGCTTTGCAAGATGCTGGTGTGGACATC
GCACAATTGCAGGCTGGGGCAGGGGCGTCGGGGATGAGCGTTGCGATCCTCATGGAGGATGGCAATTACGGGGCGGTGAT
CGTATCGGCCGAGAACCATATGTTCGACGTAGATGCCGTGCAGATACCGGACGAATGCCGCCTCGTTCTGTTGCAAAATG
AGATGGCGGCCGGTGTGATCCCGGCCATGGCGACGAAGGCCCAACGCGCGGGTGCCGGGGTGATCTTGAACGCCGCACCG
GCGCAGGGCGTTGGCAAGACCGACCTTGCGCATCTCCACACGCTGATCGTGAACCGGGTCGAAGGGGCCGATCTGTTGGG
CATTGCGGACAGCGCACCTGATCCGGTGGCGGTGGTCAATGGCCTGCAAGAGCTGGCCCCGCAGGCGCTGGTGATCCTGA
CACTCGGTGGGGACGGCGTTGTTTTCGCTGAGCCGGGCCGGGCAGTGCAGTCACAAGCCGCGCGCCGGGTCTCGGTACAC
TCCACCCACGGGGCGGGTGACGTGTTTGTCGGCGCTTACGCGGCGGCGATCCTGGCGGGGCAATCGCTGTCTGAAGCCAT
CCAGTTGGGGCAAGCCGCAGCCGCCGCCCACATCTCTCAGATCCGGTAG

Upstream 100 bases:

>100_bases
TTGCGGAAAGTCTGATGGAAGATCCAGCGCTGGCGCAGGCGATTGACCGGCAGGATGCGGCGGCATCACACCGGATCGTC
GCGCGGGCCTTGTACGGCTC

Downstream 100 bases:

>100_bases
AACGCCGCCGCCGTGCCACCAAAGATCATATCCTGTGCGCCACGGGACAGATGTGCCGTCAATGCTTCCGCCGCATTGCC
CCATTCATCATAGGTGGCTT

Product: PfkB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSLLVVGALHWDVVVQASRLPRIDETLRGSGVTYQFGGKAGNQAIAAAGAGADVGFAGRNGTDEAGQSMQAALQDAGVDI
AQLQAGAGASGMSVAILMEDGNYGAVIVSAENHMFDVDAVQIPDECRLVLLQNEMAAGVIPAMATKAQRAGAGVILNAAP
AQGVGKTDLAHLHTLIVNRVEGADLLGIADSAPDPVAVVNGLQELAPQALVILTLGGDGVVFAEPGRAVQSQAARRVSVH
STHGAGDVFVGAYAAAILAGQSLSEAIQLGQAAAAAHISQIR

Sequences:

>Translated_282_residues
MSLLVVGALHWDVVVQASRLPRIDETLRGSGVTYQFGGKAGNQAIAAAGAGADVGFAGRNGTDEAGQSMQAALQDAGVDI
AQLQAGAGASGMSVAILMEDGNYGAVIVSAENHMFDVDAVQIPDECRLVLLQNEMAAGVIPAMATKAQRAGAGVILNAAP
AQGVGKTDLAHLHTLIVNRVEGADLLGIADSAPDPVAVVNGLQELAPQALVILTLGGDGVVFAEPGRAVQSQAARRVSVH
STHGAGDVFVGAYAAAILAGQSLSEAIQLGQAAAAAHISQIR
>Mature_281_residues
SLLVVGALHWDVVVQASRLPRIDETLRGSGVTYQFGGKAGNQAIAAAGAGADVGFAGRNGTDEAGQSMQAALQDAGVDIA
QLQAGAGASGMSVAILMEDGNYGAVIVSAENHMFDVDAVQIPDECRLVLLQNEMAAGVIPAMATKAQRAGAGVILNAAPA
QGVGKTDLAHLHTLIVNRVEGADLLGIADSAPDPVAVVNGLQELAPQALVILTLGGDGVVFAEPGRAVQSQAARRVSVHS
THGAGDVFVGAYAAAILAGQSLSEAIQLGQAAAAAHISQIR

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=289, Percent_Identity=28.0276816608997, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1790193, Length=272, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17532905, Length=288, Percent_Identity=28.4722222222222, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319884, Length=319, Percent_Identity=26.6457680250784, Blast_Score=98, Evalue=1e-21,
Organism=Drosophila melanogaster, GI20128807, Length=270, Percent_Identity=32.2222222222222, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 28333; Mature: 28202

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLVVGALHWDVVVQASRLPRIDETLRGSGVTYQFGGKAGNQAIAAAGAGADVGFAGRN
CCEEEEEEEHEEEEEEHHCCCCHHHHHCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCC
GTDEAGQSMQAALQDAGVDIAQLQAGAGASGMSVAILMEDGNYGAVIVSAENHMFDVDAV
CCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEEEEEECCCCCEEEEECCCCEEECEEE
QIPDECRLVLLQNEMAAGVIPAMATKAQRAGAGVILNAAPAQGVGKTDLAHLHTLIVNRV
ECCHHHEEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHC
EGADLLGIADSAPDPVAVVNGLQELAPQALVILTLGGDGVVFAEPGRAVQSQAARRVSVH
CCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCCHHHHHHHHEEEEE
STHGAGDVFVGAYAAAILAGQSLSEAIQLGQAAAAAHISQIR
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLLVVGALHWDVVVQASRLPRIDETLRGSGVTYQFGGKAGNQAIAAAGAGADVGFAGRN
CEEEEEEEHEEEEEEHHCCCCHHHHHCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCC
GTDEAGQSMQAALQDAGVDIAQLQAGAGASGMSVAILMEDGNYGAVIVSAENHMFDVDAV
CCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEEEEEECCCCCEEEEECCCCEEECEEE
QIPDECRLVLLQNEMAAGVIPAMATKAQRAGAGVILNAAPAQGVGKTDLAHLHTLIVNRV
ECCHHHEEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHC
EGADLLGIADSAPDPVAVVNGLQELAPQALVILTLGGDGVVFAEPGRAVQSQAARRVSVH
CCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCCHHHHHHHHEEEEE
STHGAGDVFVGAYAAAILAGQSLSEAIQLGQAAAAAHISQIR
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]