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The map label for this gene is fabD [H]

Identifier: 89054115

GI number: 89054115

Start: 1611555

End: 1612496

Strand: Direct

Name: fabD [H]

Synonym: Jann_1624

Alternate gene names: 89054115

Gene position: 1611555-1612496 (Clockwise)

Preceding gene: 89054114

Following gene: 89054116

Centisome position: 37.32

GC content: 67.73

Gene sequence:

>942_bases
ATGACCCGAGCCTTTATCTTTCCCGGCCAGGGGGCCCAGACCATTGGTATGGGCCGCGCCCTCGCAGACGCTTATCCGGC
CGCAAGGGCCGTCTTCGCAGAGGTGGATGACGCCTTGGGCGAAAGCCTGTCATCCCTGATCTGGGAGGGCGAGATTGAAG
ACCTGACCCTGACCCGGAACGCGCAGCCTGCGCTGATGGCCACATCGCTGGCGGCCATGGCGGCGCTGGGGGCCGAGGGG
GTTGAGGTCACGGCGGCGTCCTATGTGGCGGGTCATTCCCTGGGCGAATATTCCGCCCTTGCGGCTGCGGGGGCGTTGAG
CCTGGCCGATACGGCCCGTCTGTTGCGCCTGCGCGGCGAGGCGATGCAGGCGGCGGTGCCTGCGGGTGAGGGGGCGATGG
CCGCGATCCTTGGCCTTGATCTGGCCAATGTCGAAGAGGTGGCGGCAGAGGCCGCGCAGGGCGACGTGTGCGAGGCCGCT
AACGACAACGATCCCGCGCAGGTGGTGATTTCCGGCACAAAGGCAGCCGTGGAACGCGCGTGCGACATTGCCAAGGCCCG
GGGGGCCAAGCGGGCACTTTTGCTGCCCGTGTCGGCTCCGTTCCATTGTGCGCTGATGCAACCTGCCGCCGACGCGATGG
CCCAGGCGCTGTCGGAGGTCGATATGGAAGCGCCGGTCGTGCCGCTGGTGGGTAATGTGATCGCCCAGGCCGAAAGCTCG
GCCATGGTGATCCGCAACAATCTGGTCGATCAGGTGACAGGCCGGGTGCGCTGGCGCGAGTCAGTGCTTTGGATGGCGGC
GGAGGGCGTGACAGAGGTGTTCGAGATCGGCGCGGGCAAGGCGCTCTCGGGCATGGTCAAACGCATCGACCGGGCGGTGA
CGCCCCACGCGGTGGGCACGCCGGAGGATGTGACGAAGGCCGTTGAGGCGCTGGCCCGATGA

Upstream 100 bases:

>100_bases
GGTGGGGTCCCTGTCGACGGGGCCCCACCGTCTTGCGTTGCGAAAGGCCTGCGGCTCCTGTAGCTCCTGTCGGCACAAAG
TGACGTAGGAGCCAGCGCCC

Downstream 100 bases:

>100_bases
GTTTTGAGGAGGCCCTGGCCTTGCAACCCACCTGGGTGCAGATCTGGTTGAATGTCCTGCTGTTCGGCGCGTTCATCCTG
CCGCTGAGTTTCCTGATCTG

Product: [Acyl-carrier-protein] S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTRAFIFPGQGAQTIGMGRALADAYPAARAVFAEVDDALGESLSSLIWEGEIEDLTLTRNAQPALMATSLAAMAALGAEG
VEVTAASYVAGHSLGEYSALAAAGALSLADTARLLRLRGEAMQAAVPAGEGAMAAILGLDLANVEEVAAEAAQGDVCEAA
NDNDPAQVVISGTKAAVERACDIAKARGAKRALLLPVSAPFHCALMQPAADAMAQALSEVDMEAPVVPLVGNVIAQAESS
AMVIRNNLVDQVTGRVRWRESVLWMAAEGVTEVFEIGAGKALSGMVKRIDRAVTPHAVGTPEDVTKAVEALAR

Sequences:

>Translated_313_residues
MTRAFIFPGQGAQTIGMGRALADAYPAARAVFAEVDDALGESLSSLIWEGEIEDLTLTRNAQPALMATSLAAMAALGAEG
VEVTAASYVAGHSLGEYSALAAAGALSLADTARLLRLRGEAMQAAVPAGEGAMAAILGLDLANVEEVAAEAAQGDVCEAA
NDNDPAQVVISGTKAAVERACDIAKARGAKRALLLPVSAPFHCALMQPAADAMAQALSEVDMEAPVVPLVGNVIAQAESS
AMVIRNNLVDQVTGRVRWRESVLWMAAEGVTEVFEIGAGKALSGMVKRIDRAVTPHAVGTPEDVTKAVEALAR
>Mature_312_residues
TRAFIFPGQGAQTIGMGRALADAYPAARAVFAEVDDALGESLSSLIWEGEIEDLTLTRNAQPALMATSLAAMAALGAEGV
EVTAASYVAGHSLGEYSALAAAGALSLADTARLLRLRGEAMQAAVPAGEGAMAAILGLDLANVEEVAAEAAQGDVCEAAN
DNDPAQVVISGTKAAVERACDIAKARGAKRALLLPVSAPFHCALMQPAADAMAQALSEVDMEAPVVPLVGNVIAQAESSA
MVIRNNLVDQVTGRVRWRESVLWMAAEGVTEVFEIGAGKALSGMVKRIDRAVTPHAVGTPEDVTKAVEALAR

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=301, Percent_Identity=32.890365448505, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=40.3669724770642, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787334, Length=310, Percent_Identity=48.3870967741936, Blast_Score=253, Evalue=9e-69,
Organism=Caenorhabditis elegans, GI71984332, Length=291, Percent_Identity=31.2714776632302, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17550940, Length=298, Percent_Identity=29.8657718120805, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24665753, Length=304, Percent_Identity=33.8815789473684, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32115; Mature: 31984

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRAFIFPGQGAQTIGMGRALADAYPAARAVFAEVDDALGESLSSLIWEGEIEDLTLTRN
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
AQPALMATSLAAMAALGAEGVEVTAASYVAGHSLGEYSALAAAGALSLADTARLLRLRGE
CCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AMQAAVPAGEGAMAAILGLDLANVEEVAAEAAQGDVCEAANDNDPAQVVISGTKAAVERA
HHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECHHHHHHHH
CDIAKARGAKRALLLPVSAPFHCALMQPAADAMAQALSEVDMEAPVVPLVGNVIAQAESS
HHHHHHCCCCEEEEEECCCCCCEEHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
AMVIRNNLVDQVTGRVRWRESVLWMAAEGVTEVFEIGAGKALSGMVKRIDRAVTPHAVGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
PEDVTKAVEALAR
HHHHHHHHHHHCC
>Mature Secondary Structure 
TRAFIFPGQGAQTIGMGRALADAYPAARAVFAEVDDALGESLSSLIWEGEIEDLTLTRN
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
AQPALMATSLAAMAALGAEGVEVTAASYVAGHSLGEYSALAAAGALSLADTARLLRLRGE
CCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AMQAAVPAGEGAMAAILGLDLANVEEVAAEAAQGDVCEAANDNDPAQVVISGTKAAVERA
HHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECHHHHHHHH
CDIAKARGAKRALLLPVSAPFHCALMQPAADAMAQALSEVDMEAPVVPLVGNVIAQAESS
HHHHHHCCCCEEEEEECCCCCCEEHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
AMVIRNNLVDQVTGRVRWRESVLWMAAEGVTEVFEIGAGKALSGMVKRIDRAVTPHAVGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
PEDVTKAVEALAR
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]