Click here to switch to the map view.

The map label for this gene is yngJ [H]

Identifier: 89053993

GI number: 89053993

Start: 1472397

End: 1473437

Strand: Reverse

Name: yngJ [H]

Synonym: Jann_1502

Alternate gene names: 89053993

Gene position: 1473437-1472397 (Counterclockwise)

Preceding gene: 89053994

Following gene: 89053987

Centisome position: 34.12

GC content: 62.06

Gene sequence:

>1041_bases
GTGAACTTTGAGCAGACCGACGACCGCCGCATGTTGGCCGAGACGCTGCGCCGCTACCTTACGGACGCTTACGGCATGGA
GCATCGCACCGCCACAGCCTACGACGCGCCGTTCCATAACCCTGAAAAATGGGCAGAATTGACCGAGTTGGGCATCTTCT
ATGCGTTGGTGGATGAGGGTAAAGGCGGCATGGGCGGCCACGGGTTCGATATTGTCTGCGTCTTTGAAGAATTGGGCCGC
GCGTTGTGTCCCGAGCCGGTCCTGGGCCAGGTTTTGGCGGCCTCCCTCCTCGACGATCCGGAGGCACTTCTGGGCGGCAC
GCGCTACGCCCTCGCGATCAGCGAGACCGACGCGCCCTATGATATCCGCGACCTCACCACGGAGGCGGTGGACGGGCGGT
TAACGGGGCGCAAGACGGTGGTCTACGGCGCGCCCACGGCGGAGATTTTGCTGGTCGCTGCCAGGCAGGGCGATGATATC
GCAGTGTTCCAAATGCCTGCGTCGGAGGCCGACATTACAGGCTACGCGATGATCGACGGCGGCCCGGCGGGGGAGGTTTT
CTTCGACAACACACCTGCAACTTTGATCATGGACAACGCGGAATGCGCCTTGCAGACCGCGCTGGATCGCGGGGCGCTGG
CGCTATGTGCCGAAGCGCTTGGCGCGATGGGCGTGGTGCAGGACATGCTTGTCGACTACCTGAAGACCCGCACGCAATTC
GGCCAGCCTCTGGGGGCGTTTCAGGTCCTGCAACATCGCACGATTGATCTGGCGATCGAGATCGAACAGGCGCGATCAAT
CATCATCCTCGCAGCCTCCGCCGATGGGACCGACGCTTTCCCCAAACGGGCCGCGCAGGCCAAACATCTGGTGGGCAAAA
TCGCGCGTCAGGTCGCGGAGGAGGCGATCCAGATGCATGGCGGGATCGGGATCACATGGGAGTATCCGCTGTCGCATTAT
GCCAAGCGTCTGGTGATGATCGACCACCAATTGGGCGACAGCGACTGGCATCTGGAACGGTTAATGGCGGATTTGGCATA
G

Upstream 100 bases:

>100_bases
ACGCCCACAACGCGGCGGGGTATTTCAACAACCGCAAAATCTCCATCTACGGCGGCTCGAACGAGATCCAGCGCAACATT
CTGGCCAAGGGATTGATGCA

Downstream 100 bases:

>100_bases
GAGAGCCATCGCGACGGTGCACATAGAGGCGGCGGCGGGATTGAGTTGTATTTGCCCAGATGAAACAGGAGCCGCGCACT
AAGCCGGAGAGGTTGAATGC

Product: acyl-CoA dehydrogenase-like protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MNFEQTDDRRMLAETLRRYLTDAYGMEHRTATAYDAPFHNPEKWAELTELGIFYALVDEGKGGMGGHGFDIVCVFEELGR
ALCPEPVLGQVLAASLLDDPEALLGGTRYALAISETDAPYDIRDLTTEAVDGRLTGRKTVVYGAPTAEILLVAARQGDDI
AVFQMPASEADITGYAMIDGGPAGEVFFDNTPATLIMDNAECALQTALDRGALALCAEALGAMGVVQDMLVDYLKTRTQF
GQPLGAFQVLQHRTIDLAIEIEQARSIIILAASADGTDAFPKRAAQAKHLVGKIARQVAEEAIQMHGGIGITWEYPLSHY
AKRLVMIDHQLGDSDWHLERLMADLA

Sequences:

>Translated_346_residues
MNFEQTDDRRMLAETLRRYLTDAYGMEHRTATAYDAPFHNPEKWAELTELGIFYALVDEGKGGMGGHGFDIVCVFEELGR
ALCPEPVLGQVLAASLLDDPEALLGGTRYALAISETDAPYDIRDLTTEAVDGRLTGRKTVVYGAPTAEILLVAARQGDDI
AVFQMPASEADITGYAMIDGGPAGEVFFDNTPATLIMDNAECALQTALDRGALALCAEALGAMGVVQDMLVDYLKTRTQF
GQPLGAFQVLQHRTIDLAIEIEQARSIIILAASADGTDAFPKRAAQAKHLVGKIARQVAEEAIQMHGGIGITWEYPLSHY
AKRLVMIDHQLGDSDWHLERLMADLA
>Mature_346_residues
MNFEQTDDRRMLAETLRRYLTDAYGMEHRTATAYDAPFHNPEKWAELTELGIFYALVDEGKGGMGGHGFDIVCVFEELGR
ALCPEPVLGQVLAASLLDDPEALLGGTRYALAISETDAPYDIRDLTTEAVDGRLTGRKTVVYGAPTAEILLVAARQGDDI
AVFQMPASEADITGYAMIDGGPAGEVFFDNTPATLIMDNAECALQTALDRGALALCAEALGAMGVVQDMLVDYLKTRTQF
GQPLGAFQVLQHRTIDLAIEIEQARSIIILAASADGTDAFPKRAAQAKHLVGKIARQVAEEAIQMHGGIGITWEYPLSHY
AKRLVMIDHQLGDSDWHLERLMADLA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=362, Percent_Identity=25.414364640884, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI226958414, Length=321, Percent_Identity=26.1682242990654, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4501859, Length=115, Percent_Identity=34.7826086956522, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4557233, Length=122, Percent_Identity=36.8852459016393, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4501857, Length=320, Percent_Identity=21.25, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17538396, Length=311, Percent_Identity=27.3311897106109, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 37600; Mature: 37600

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFEQTDDRRMLAETLRRYLTDAYGMEHRTATAYDAPFHNPEKWAELTELGIFYALVDEG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHEEEEEEECC
KGGMGGHGFDIVCVFEELGRALCPEPVLGQVLAASLLDDPEALLGGTRYALAISETDAPY
CCCCCCCCEEEEEEHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHCCCEEEEEEECCCCCC
DIRDLTTEAVDGRLTGRKTVVYGAPTAEILLVAARQGDDIAVFQMPASEADITGYAMIDG
CHHHHHHHHHCCEECCCEEEEEECCHHHEEEEEECCCCCEEEEECCCCCCCCCEEEEECC
GPAGEVFFDNTPATLIMDNAECALQTALDRGALALCAEALGAMGVVQDMLVDYLKTRTQF
CCCCCEEECCCCCEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQPLGAFQVLQHRTIDLAIEIEQARSIIILAASADGTDAFPKRAAQAKHLVGKIARQVAE
CCCHHHHHHHHCCCEEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
EAIQMHGGIGITWEYPLSHYAKRLVMIDHQLGDSDWHLERLMADLA
HHHHHHCCEEEEEECCHHHHHHHHHEEECCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNFEQTDDRRMLAETLRRYLTDAYGMEHRTATAYDAPFHNPEKWAELTELGIFYALVDEG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHEEEEEEECC
KGGMGGHGFDIVCVFEELGRALCPEPVLGQVLAASLLDDPEALLGGTRYALAISETDAPY
CCCCCCCCEEEEEEHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHCCCEEEEEEECCCCCC
DIRDLTTEAVDGRLTGRKTVVYGAPTAEILLVAARQGDDIAVFQMPASEADITGYAMIDG
CHHHHHHHHHCCEECCCEEEEEECCHHHEEEEEECCCCCEEEEECCCCCCCCCEEEEECC
GPAGEVFFDNTPATLIMDNAECALQTALDRGALALCAEALGAMGVVQDMLVDYLKTRTQF
CCCCCEEECCCCCEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQPLGAFQVLQHRTIDLAIEIEQARSIIILAASADGTDAFPKRAAQAKHLVGKIARQVAE
CCCHHHHHHHHCCCEEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
EAIQMHGGIGITWEYPLSHYAKRLVMIDHQLGDSDWHLERLMADLA
HHHHHHCCEEEEEECCHHHHHHHHHEEECCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]