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The map label for this gene is dacC [H]

Identifier: 89053769

GI number: 89053769

Start: 1238527

End: 1239723

Strand: Reverse

Name: dacC [H]

Synonym: Jann_1278

Alternate gene names: 89053769

Gene position: 1239723-1238527 (Counterclockwise)

Preceding gene: 89053770

Following gene: 89053768

Centisome position: 28.71

GC content: 64.58

Gene sequence:

>1197_bases
ATGCAAATCGCTACTCTGACAAAACCCGTCGCAACCCTCCTTGCGGCGGGTTGTTTCTTCGTCTCAAGCCTGATGGCCAA
CGCCCAAGGCTATGAGACTCAGGCCCGCGCGGCCTATGTCTATGATCACGCCTCGGGACAGGTGCTGCTGGCGCTGAACG
CGGATGAGGCGCTGCCGCCCGCGTCGATGTCCAAGCTGATGACGCTGCTGATGGCATTTGAGGCACTGCGCGACGGCCGC
CTGACGTTGGAGACGCGCGTGCCGGTGTCCGAGCACGCGATGAGCTTTGGCGGCTCCACCATGTTCCTCAACACCCAGGA
CCGCCCCACGATTGAAGAGCTGATCCGGGGCGTTGTCATCGTCTCGGGCAATGACGCCTCGGTGGTCTTGGGCGAAGCGC
TGTCACCCGACGGCACGGAAGAGGGCTTTGCCACGATGATGACCCAGCGCGCGCAACAATTGGGGATGATGAACTCCACC
TTCCGGAATGCCTCCGGCTGGCCCGCCGACGGCCATGCCATGTCGATGCGCGATCTGGGCATTCTGGCGCAGCGGCTGAT
CGAAGAATTTCCGGAATATTATGGCTACTTCGTGGAAACGGAGTTTGATTACGAGGACCGCAGCCCTGCGAACCGCTTTA
ACCGCAATCCGCTTCTGGGTCTGGGGATCGGGGCCGATGGGTTGAAGACCGGCCACACCCAGGAAGCCGGGTTCGGCCTT
GTCGGCTCGGCCATGCAGGGGGACCGGCGGGTGACCTTCGTGATCACCGGCCTCGACAGTGCCGACGCGCGCGCCGCAGA
GGCCGAGCGCCTGGTCACCTGGGCCTTCCGGCAATTCGTGATGCGCGACGTGGTGGAGCCCGGCGTTGAACTGGCCCGCG
CACCGGTGTTTCTGGGGTCCCAGGAGACGGTCGGCCTCGCCCCATCGGAGGGGATCGAAATGCTTCTGCCCGCCCTTCTG
GATCCTGAAATCGAGGCCAATTTGACGTACACCAGCCCCCTGCAGGCCCCCGTGAGCGCAGGCGATGTGGTGGGAGAATT
GCACGTGGTCCAAACCGTCCATGGATTTGAGGCACGTGTCCCCGTCGTTGTGATGGACGACGTCCCCCGTGGCGGCCCGA
TGGTGCGGGTCGGCGCAGCCTGGTCCAGCGTGATCGGCCTGGTATCCCGCGGCGAGGCCGACGCGCCGCCGTCCTGA

Upstream 100 bases:

>100_bases
GGTGGGCCCCGCCGATAGCGAGGGCTCGCGCGATGCGATCCTGGCAAGTGTCCGTGATCTTGGCTTTGATGATGCCTTTT
TCGTAAGACGCTAGGACGCC

Downstream 100 bases:

>100_bases
GCGCACCCCCCTCGGGACCGGAACCCGCCCAACTCACCCGGCGCCGCCCTGGCGGCACCCGCAACCATCTGCGCCAAACC
ACGCGCCGCTGAGCGGCCCG

Product: Serine-type D-Ala-D-Ala carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MQIATLTKPVATLLAAGCFFVSSLMANAQGYETQARAAYVYDHASGQVLLALNADEALPPASMSKLMTLLMAFEALRDGR
LTLETRVPVSEHAMSFGGSTMFLNTQDRPTIEELIRGVVIVSGNDASVVLGEALSPDGTEEGFATMMTQRAQQLGMMNST
FRNASGWPADGHAMSMRDLGILAQRLIEEFPEYYGYFVETEFDYEDRSPANRFNRNPLLGLGIGADGLKTGHTQEAGFGL
VGSAMQGDRRVTFVITGLDSADARAAEAERLVTWAFRQFVMRDVVEPGVELARAPVFLGSQETVGLAPSEGIEMLLPALL
DPEIEANLTYTSPLQAPVSAGDVVGELHVVQTVHGFEARVPVVVMDDVPRGGPMVRVGAAWSSVIGLVSRGEADAPPS

Sequences:

>Translated_398_residues
MQIATLTKPVATLLAAGCFFVSSLMANAQGYETQARAAYVYDHASGQVLLALNADEALPPASMSKLMTLLMAFEALRDGR
LTLETRVPVSEHAMSFGGSTMFLNTQDRPTIEELIRGVVIVSGNDASVVLGEALSPDGTEEGFATMMTQRAQQLGMMNST
FRNASGWPADGHAMSMRDLGILAQRLIEEFPEYYGYFVETEFDYEDRSPANRFNRNPLLGLGIGADGLKTGHTQEAGFGL
VGSAMQGDRRVTFVITGLDSADARAAEAERLVTWAFRQFVMRDVVEPGVELARAPVFLGSQETVGLAPSEGIEMLLPALL
DPEIEANLTYTSPLQAPVSAGDVVGELHVVQTVHGFEARVPVVVMDDVPRGGPMVRVGAAWSSVIGLVSRGEADAPPS
>Mature_398_residues
MQIATLTKPVATLLAAGCFFVSSLMANAQGYETQARAAYVYDHASGQVLLALNADEALPPASMSKLMTLLMAFEALRDGR
LTLETRVPVSEHAMSFGGSTMFLNTQDRPTIEELIRGVVIVSGNDASVVLGEALSPDGTEEGFATMMTQRAQQLGMMNST
FRNASGWPADGHAMSMRDLGILAQRLIEEFPEYYGYFVETEFDYEDRSPANRFNRNPLLGLGIGADGLKTGHTQEAGFGL
VGSAMQGDRRVTFVITGLDSADARAAEAERLVTWAFRQFVMRDVVEPGVELARAPVFLGSQETVGLAPSEGIEMLLPALL
DPEIEANLTYTSPLQAPVSAGDVVGELHVVQTVHGFEARVPVVVMDDVPRGGPMVRVGAAWSSVIGLVSRGEADAPPS

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=352, Percent_Identity=36.3636363636364, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI87082022, Length=354, Percent_Identity=32.4858757062147, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1786851, Length=384, Percent_Identity=30.46875, Blast_Score=176, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 42602; Mature: 42602

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIATLTKPVATLLAAGCFFVSSLMANAQGYETQARAAYVYDHASGQVLLALNADEALPP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCC
ASMSKLMTLLMAFEALRDGRLTLETRVPVSEHAMSFGGSTMFLNTQDRPTIEELIRGVVI
HHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCEEEEECCCCCHHHHHHCCEEE
VSGNDASVVLGEALSPDGTEEGFATMMTQRAQQLGMMNSTFRNASGWPADGHAMSMRDLG
EECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCEEHHHHHH
ILAQRLIEEFPEYYGYFVETEFDYEDRSPANRFNRNPLLGLGIGADGLKTGHTQEAGFGL
HHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHCCCCCEEEEECCCCCCCCCCCCCCCCCE
VGSAMQGDRRVTFVITGLDSADARAAEAERLVTWAFRQFVMRDVVEPGVELARAPVFLGS
ECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEECC
QETVGLAPSEGIEMLLPALLDPEIEANLTYTSPLQAPVSAGDVVGELHVVQTVHGFEARV
CCCCCCCCCCCHHHHHHHHCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
PVVVMDDVPRGGPMVRVGAAWSSVIGLVSRGEADAPPS
CEEEECCCCCCCCEEEECHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQIATLTKPVATLLAAGCFFVSSLMANAQGYETQARAAYVYDHASGQVLLALNADEALPP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCC
ASMSKLMTLLMAFEALRDGRLTLETRVPVSEHAMSFGGSTMFLNTQDRPTIEELIRGVVI
HHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCEEEEECCCCCHHHHHHCCEEE
VSGNDASVVLGEALSPDGTEEGFATMMTQRAQQLGMMNSTFRNASGWPADGHAMSMRDLG
EECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCEEHHHHHH
ILAQRLIEEFPEYYGYFVETEFDYEDRSPANRFNRNPLLGLGIGADGLKTGHTQEAGFGL
HHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHCCCCCEEEEECCCCCCCCCCCCCCCCCE
VGSAMQGDRRVTFVITGLDSADARAAEAERLVTWAFRQFVMRDVVEPGVELARAPVFLGS
ECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEECC
QETVGLAPSEGIEMLLPALLDPEIEANLTYTSPLQAPVSAGDVVGELHVVQTVHGFEARV
CCCCCCCCCCCHHHHHHHHCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
PVVVMDDVPRGGPMVRVGAAWSSVIGLVSRGEADAPPS
CEEEECCCCCCCCEEEECHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]