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The map label for this gene is nhaR [H]

Identifier: 89053751

GI number: 89053751

Start: 1218977

End: 1219855

Strand: Direct

Name: nhaR [H]

Synonym: Jann_1260

Alternate gene names: 89053751

Gene position: 1218977-1219855 (Clockwise)

Preceding gene: 89053748

Following gene: 89053752

Centisome position: 28.23

GC content: 62.23

Gene sequence:

>879_bases
ATGGCAGAGTTCAATTATCACCATTTGCGATACTTCTGGGCGGTCGCCCATGACGGCAACCTCACGCGGACGGCGGCGCG
GCTCAACCTGTCGCAATCTGCCGTCTCCGTTCAGATCAAGCAGCTTGAGGCGTCCCTGGGGCATCGGTTGTTTGAGCGGC
GCGGTCGTCAGCTTGTCCTGACCGAGGCGGGCCGGATCGCGCTGGATCATGCGGATGCAATCTTTGCCGCGGGGCGCGAG
TTGATTGGCACGCTTCAGGAAAAAGACCGTAGCCGCCAAGCCATCCGGATCGGCGCGTTGGCGACCCTGTCGCGCAATTT
TCATCTGAAGTTTTTGCAACCCATCCTTGGCCGGCAGGATGTGGAGATCATCCTGCGCTCCGGCACGAATGTGAACTTGT
TGCAGGCGCTGGAAGCGCACAATCTGGACGTGGTCCTGATCAATCGCCCGCCTTCGCGCGACGCCATCACGCCATTCGTG
TCCCACCGCCTGTCCGAGCAGCCGGTCAGCCTGGTGGGCACGCCTGCTTTGCTGGGAGATACGCCTGATCTGAATGACCT
GCTGGCCCATCAGCCGATCATCCTGCCCACCGCCGACACCGACGTGCGCATTGGATTTGACGCGCTCACCGAGCGGATCG
GCATCCGGCCCCAGATCGTCGCGGAGGTCGAGGACATGGCGATGATGCGCCTTCTCGCGCGGGAGGGGGTTGGTCTGGCG
GTCCTGCCGCCTATCGTGGTCCAAGACGAGCTGAAAACCGGACGGTTGATTGAGGCGGACCGTCTTCCCGGCATTGGTGA
GACGTTCTATGCGGTCACCCTGACACGCCGTTTCCCGAACCCGCTGCTGTCGGAATTGCTGGAAGACCGCGCGTTGTAG

Upstream 100 bases:

>100_bases
GGGCATCCTTCTGACAGACCGTGTCCGGTTCAGATAGCAGCCTCATCTACGTTAGAAAAATTCATTGTTTAGCGGAAATC
ATTCTGTTTAATATATTGAT

Downstream 100 bases:

>100_bases
CGGCGTTTGCGCCCATGGCTATGTCGCGGTTGCCACAATCAGGACGGGAAAGGACCAATGATCCAACGCCCCTAAGGTGA
AAATCTCTGGCCAACGCTGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MAEFNYHHLRYFWAVAHDGNLTRTAARLNLSQSAVSVQIKQLEASLGHRLFERRGRQLVLTEAGRIALDHADAIFAAGRE
LIGTLQEKDRSRQAIRIGALATLSRNFHLKFLQPILGRQDVEIILRSGTNVNLLQALEAHNLDVVLINRPPSRDAITPFV
SHRLSEQPVSLVGTPALLGDTPDLNDLLAHQPIILPTADTDVRIGFDALTERIGIRPQIVAEVEDMAMMRLLAREGVGLA
VLPPIVVQDELKTGRLIEADRLPGIGETFYAVTLTRRFPNPLLSELLEDRAL

Sequences:

>Translated_292_residues
MAEFNYHHLRYFWAVAHDGNLTRTAARLNLSQSAVSVQIKQLEASLGHRLFERRGRQLVLTEAGRIALDHADAIFAAGRE
LIGTLQEKDRSRQAIRIGALATLSRNFHLKFLQPILGRQDVEIILRSGTNVNLLQALEAHNLDVVLINRPPSRDAITPFV
SHRLSEQPVSLVGTPALLGDTPDLNDLLAHQPIILPTADTDVRIGFDALTERIGIRPQIVAEVEDMAMMRLLAREGVGLA
VLPPIVVQDELKTGRLIEADRLPGIGETFYAVTLTRRFPNPLLSELLEDRAL
>Mature_291_residues
AEFNYHHLRYFWAVAHDGNLTRTAARLNLSQSAVSVQIKQLEASLGHRLFERRGRQLVLTEAGRIALDHADAIFAAGREL
IGTLQEKDRSRQAIRIGALATLSRNFHLKFLQPILGRQDVEIILRSGTNVNLLQALEAHNLDVVLINRPPSRDAITPFVS
HRLSEQPVSLVGTPALLGDTPDLNDLLAHQPIILPTADTDVRIGFDALTERIGIRPQIVAEVEDMAMMRLLAREGVGLAV
LPPIVVQDELKTGRLIEADRLPGIGETFYAVTLTRRFPNPLLSELLEDRAL

Specific function: Plays a role in the positive regulation of nhaA (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=287, Percent_Identity=25.4355400696864, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI157672245, Length=259, Percent_Identity=29.7297297297297, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788297, Length=243, Percent_Identity=26.3374485596708, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI2367136, Length=248, Percent_Identity=27.0161290322581, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87081904, Length=271, Percent_Identity=31.7343173431734, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788481, Length=272, Percent_Identity=27.9411764705882, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790262, Length=277, Percent_Identity=25.6317689530686, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789204, Length=261, Percent_Identity=26.0536398467433, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32416; Mature: 32285

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEFNYHHLRYFWAVAHDGNLTRTAARLNLSQSAVSVQIKQLEASLGHRLFERRGRQLVL
CCCCCCEEEEEEEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
TEAGRIALDHADAIFAAGRELIGTLQEKDRSRQAIRIGALATLSRNFHLKFLQPILGRQD
ECCCEEEECCHHHHHHHHHHHHHHHHHHHCCHHHEEEHHHEECCCCCCHHHHHHHHCCCC
VEIILRSGTNVNLLQALEAHNLDVVLINRPPSRDAITPFVSHRLSEQPVSLVGTPALLGD
EEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHCCCCCHHHCCCCHHCCC
TPDLNDLLAHQPIILPTADTDVRIGFDALTERIGIRPQIVAEVEDMAMMRLLAREGVGLA
CCCHHHHHHCCCEEEECCCCCEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEE
VLPPIVVQDELKTGRLIEADRLPGIGETFYAVTLTRRFPNPLLSELLEDRAL
ECCCEEEECCCCCCCEEECCCCCCCCCCEEEEEEEHHCCCHHHHHHHHHCCC
>Mature Secondary Structure 
AEFNYHHLRYFWAVAHDGNLTRTAARLNLSQSAVSVQIKQLEASLGHRLFERRGRQLVL
CCCCCEEEEEEEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
TEAGRIALDHADAIFAAGRELIGTLQEKDRSRQAIRIGALATLSRNFHLKFLQPILGRQD
ECCCEEEECCHHHHHHHHHHHHHHHHHHHCCHHHEEEHHHEECCCCCCHHHHHHHHCCCC
VEIILRSGTNVNLLQALEAHNLDVVLINRPPSRDAITPFVSHRLSEQPVSLVGTPALLGD
EEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHCCCCCHHHCCCCHHCCC
TPDLNDLLAHQPIILPTADTDVRIGFDALTERIGIRPQIVAEVEDMAMMRLLAREGVGLA
CCCHHHHHHCCCEEEECCCCCEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEE
VLPPIVVQDELKTGRLIEADRLPGIGETFYAVTLTRRFPNPLLSELLEDRAL
ECCCEEEECCCCCCCEEECCCCCCCCCCEEEEEEEHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]