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The map label for this gene is setC [H]

Identifier: 89052500

GI number: 89052500

Start: 9144

End: 10322

Strand: Direct

Name: setC [H]

Synonym: Jann_0009

Alternate gene names: 89052500

Gene position: 9144-10322 (Clockwise)

Preceding gene: 89052499

Following gene: 89052501

Centisome position: 0.21

GC content: 63.19

Gene sequence:

>1179_bases
ATGGCCCCCACATCCATCAGCCGCTTCGCGCCGTTCCTGCTGCTGCTTTTCATCGGAACGCTCAGCAATTCCGCGATTGT
GCCGTTCATGGGCTTCTACCTGATTGACGGTCTGGGGCACCCGCCGTGGATGCTCAGCGTTTATTCCTTCCTTGCCATCG
TGCTGACGGTTCTGGCGAACCGGGCCTTCGGGCGCCGGATTGATGCGGGTGCGCCGGTGTTCCCGCTTATCGGGGTCGCC
GCAAGCGGGTATGCGGTTGCCTCTCTGGTCATGGCGGTTTCACCGACCCTGCCCGTCATGCTGACGATTGGCGTCCTGGG
ATATGGCATCAGCGCTTCGGCCATTTCGACGATGTTCAGCCTTGGTGGTCACATGGCCGAACGGCATGGGGTGGAGCGCA
CGCGCTTCAACGCCATCATGCGGGCGACCACGTCGACGGCCTGGATGATTGGCCCCGCCATCAGCTATGTTTCTGCCGGG
CAATTCGGGAATGAAATCGTCTTCAAGGGCGCCGCCGTTTTGGGCCTGGCGTGGCTGGCCTGGTGGTTTTTGACCCTGCC
CCGGGATGTTCAGGCGAAAGCGCCGGAGAAACCGCCCGCGACAGGCCCCGTGCCCGCCAATACCGGCCTGTGGCTGGCAG
CGGCCTTCATCTTCGCAATGTCCGTGGCCCACGGCCTGACCTTCACGGCCCTGCCGCTGTTTTTCGTGACCGAGGTTGGC
CTGCCGGACTTTGCACCCGGCTTCGCGTTCTCGGTCAAAACCTTTGTGGAGGTCTTTGCGATCTTCTCCACCCCCTTCCT
CATGGCGCGCTTCGGGCTCAGCGGGCCATTGCTGGCGACGGCTTGCATCGCCGTGGGGGCAATCCTGTTCCTGTCGCAGG
TCACGACGCTCTCGCAGATGGTGATCGGGTCGGCGTTGGAGGGGCTCTACTACGGGCTCTTCGCCAGCCTCGGGATCAGT
TATGTCCAGAGTTTCGCCCGCGACCGCCCGGCCCAGGCAACGGCGATTTATTGGAACACGCTGATGATCAGTGGGCTTTT
GTCCGGGCCTGCCGTGGGCCTGATTGCCCAGGCCACAAGCTTCCAGACCGTCATCCAGATCTCATCGGGCGGGGCGGCAG
TGGCAGCACTCGTCCTGTTGGTTGGGATCCTTCACGGGCGGCGGTTACAGGCGGTTTGA

Upstream 100 bases:

>100_bases
TCCCCCTACACTCCCTCACTCAGGCGTGTCCCACCTCCCCCAACTTCGGTTGGGGGCTTTTTCGTTTGGCACTGGCCCTG
CCCCGTGCGAGGTCCAATCC

Downstream 100 bases:

>100_bases
TGCCGAAACAAACTGTTTCCATGACGCCGCAGGGCGCGACAGCAGCCCTCTGGTACCCTTACATCTCTCGCTGATGAGGT
GCCCTACATGCCCGTCTTCC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MAPTSISRFAPFLLLLFIGTLSNSAIVPFMGFYLIDGLGHPPWMLSVYSFLAIVLTVLANRAFGRRIDAGAPVFPLIGVA
ASGYAVASLVMAVSPTLPVMLTIGVLGYGISASAISTMFSLGGHMAERHGVERTRFNAIMRATTSTAWMIGPAISYVSAG
QFGNEIVFKGAAVLGLAWLAWWFLTLPRDVQAKAPEKPPATGPVPANTGLWLAAAFIFAMSVAHGLTFTALPLFFVTEVG
LPDFAPGFAFSVKTFVEVFAIFSTPFLMARFGLSGPLLATACIAVGAILFLSQVTTLSQMVIGSALEGLYYGLFASLGIS
YVQSFARDRPAQATAIYWNTLMISGLLSGPAVGLIAQATSFQTVIQISSGGAAVAALVLLVGILHGRRLQAV

Sequences:

>Translated_392_residues
MAPTSISRFAPFLLLLFIGTLSNSAIVPFMGFYLIDGLGHPPWMLSVYSFLAIVLTVLANRAFGRRIDAGAPVFPLIGVA
ASGYAVASLVMAVSPTLPVMLTIGVLGYGISASAISTMFSLGGHMAERHGVERTRFNAIMRATTSTAWMIGPAISYVSAG
QFGNEIVFKGAAVLGLAWLAWWFLTLPRDVQAKAPEKPPATGPVPANTGLWLAAAFIFAMSVAHGLTFTALPLFFVTEVG
LPDFAPGFAFSVKTFVEVFAIFSTPFLMARFGLSGPLLATACIAVGAILFLSQVTTLSQMVIGSALEGLYYGLFASLGIS
YVQSFARDRPAQATAIYWNTLMISGLLSGPAVGLIAQATSFQTVIQISSGGAAVAALVLLVGILHGRRLQAV
>Mature_391_residues
APTSISRFAPFLLLLFIGTLSNSAIVPFMGFYLIDGLGHPPWMLSVYSFLAIVLTVLANRAFGRRIDAGAPVFPLIGVAA
SGYAVASLVMAVSPTLPVMLTIGVLGYGISASAISTMFSLGGHMAERHGVERTRFNAIMRATTSTAWMIGPAISYVSAGQ
FGNEIVFKGAAVLGLAWLAWWFLTLPRDVQAKAPEKPPATGPVPANTGLWLAAAFIFAMSVAHGLTFTALPLFFVTEVGL
PDFAPGFAFSVKTFVEVFAIFSTPFLMARFGLSGPLLATACIAVGAILFLSQVTTLSQMVIGSALEGLYYGLFASLGISY
VQSFARDRPAQATAIYWNTLMISGLLSGPAVGLIAQATSFQTVIQISSGGAAVAALVLLVGILHGRRLQAV

Specific function: Involved in the efflux of sugars. The physiological role may be the detoxification of non-metabolizable sugar analogs [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Set transporter family [H]

Homologues:

Organism=Escherichia coli, GI1790091, Length=380, Percent_Identity=24.7368421052632, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI48994875, Length=358, Percent_Identity=22.0670391061453, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788495, Length=362, Percent_Identity=24.0331491712707, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004750 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41170; Mature: 41039

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPTSISRFAPFLLLLFIGTLSNSAIVPFMGFYLIDGLGHPPWMLSVYSFLAIVLTVLAN
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
RAFGRRIDAGAPVFPLIGVAASGYAVASLVMAVSPTLPVMLTIGVLGYGISASAISTMFS
HHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHH
LGGHMAERHGVERTRFNAIMRATTSTAWMIGPAISYVSAGQFGNEIVFKGAAVLGLAWLA
HHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
WWFLTLPRDVQAKAPEKPPATGPVPANTGLWLAAAFIFAMSVAHGLTFTALPLFFVTEVG
HHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
LPDFAPGFAFSVKTFVEVFAIFSTPFLMARFGLSGPLLATACIAVGAILFLSQVTTLSQM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VIGSALEGLYYGLFASLGISYVQSFARDRPAQATAIYWNTLMISGLLSGPAVGLIAQATS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHC
FQTVIQISSGGAAVAALVLLVGILHGRRLQAV
CEEEEEECCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
APTSISRFAPFLLLLFIGTLSNSAIVPFMGFYLIDGLGHPPWMLSVYSFLAIVLTVLAN
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
RAFGRRIDAGAPVFPLIGVAASGYAVASLVMAVSPTLPVMLTIGVLGYGISASAISTMFS
HHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHH
LGGHMAERHGVERTRFNAIMRATTSTAWMIGPAISYVSAGQFGNEIVFKGAAVLGLAWLA
HHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
WWFLTLPRDVQAKAPEKPPATGPVPANTGLWLAAAFIFAMSVAHGLTFTALPLFFVTEVG
HHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
LPDFAPGFAFSVKTFVEVFAIFSTPFLMARFGLSGPLLATACIAVGAILFLSQVTTLSQM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VIGSALEGLYYGLFASLGISYVQSFARDRPAQATAIYWNTLMISGLLSGPAVGLIAQATS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHC
FQTVIQISSGGAAVAALVLLVGILHGRRLQAV
CEEEEEECCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503; 10209755; 10438463 [H]