Click here to switch to the map view.

The map label for this gene is gshA

Identifier: 88658400

GI number: 88658400

Start: 113261

End: 114493

Strand: Direct

Name: gshA

Synonym: ECH_0125

Alternate gene names: NA

Gene position: 113261-114493 (Clockwise)

Preceding gene: 88657897

Following gene: 88658053

Centisome position: 9.63

GC content: 27.9

Gene sequence:

>1233_bases
ATGACGGTAATTATTGATACATTAAATGATATATTAACAAAATATAAGTTAGATATAGAGAATTGGTTTTTTAATAAATT
TACTAAGTATAACCCGGTTTTGAATATTTCGGTTGATTTAAGAGTATCTGATTATAAGATTGCTCCGGTAGATACTAATA
TTTTTCCTGCAGGCTATAATAATTTTACTGAGCAATCCCAAATTTATGCTTCTCGATTGTTAAGGGAATATGTAGTTAAT
TATGCGAACTGTAGCAAAATTTTAATTATAGCAGAGAATCATACAAGAAATTTAAAATATATTGATAGTTTGATTGTTTT
AAAAAATATAGTTAATAATGCAGGTTTTGTTGTTGAAGTAGGGATATGTAATATAAATCAAAATATAGAACTGATTTCAT
CAACAGGACGTGTGATAAATTGTTTATGTCTTACTAATGATAATGGTGTACTTCGTGCTGGATGTAGGTTTATTCCTGAT
CTTATTTTAGTCAATAATGATATGACTAGTGGGATTCCTGAAGTACTACAAGGTTTAAAATATCAAAGTATTATGCCATC
TTTATTTTTGGGATGGTTTAATAGAAGTAAATCTAATCATTTTTCTATTTATAAAAAGTTATCCAAAGAGTTTTGTGAGA
GTTTTAATATTGATCCTTGGTTAATTTCAGCATTTTTCTCTAGTTGTAGTAATATTTGTTTTTTCAACAGTCAAGGAATT
GATGATATTGCTAATGAAGTGGATGTAGTTATTAGCAAAATACGTAATAAATTCCAATTATATAGTATTAAGGAACAGCC
ATATGTGTTTGTGAAAGCTGATAATGGAACTTATGGTATGGGAATATTAGTAGCTTATTGTGGAGATGATATCTTAATGC
TTAATAGGAAAAAGCGTAATAAAATGAAAAAGATTAAAGATGGTAATGTTGTCAGTAGTGTAATAATACAGGAAGGTATT
ACTACTAGAGAGATCTTTAATGGTTATGTAGCTGAGCCATTAGTTTATTTTATAGGGCATACTCCTTCATGTTACTTATA
CAGGTATCATTCTGTAAAGGATAGATTTTCTAATTTAAATTCTGTAGGCTGTGACTTTATAGATATAAGTTATAAACAGC
AAGACATATTGTATTGGAATATAATTGGAAAAATAGCTGTTTTAGCTGCTGCAATTGAGATGCATGAGATATCAAATGTT
AATGTAATGGAGCAAAATTGCTTACTAAGTTAA

Upstream 100 bases:

>100_bases
TAATATTACGTTAAGTAAAAATTTTTTATGCTTAACTATGGATAATTATCTTAAAGTGTTGATGTCCTATGAGTTTACTC
GCAATGTTTTATTGGTACTA

Downstream 100 bases:

>100_bases
ATTGCTAATCTTATGTGTTGTTTTTGACAATATTATTATACAAAAGTTGGTAAATATATCTGTTGATTAACATAGGATCT
ATAATGTGTTATTACAGTAT

Product: glutamate--cysteine ligase

Products: NA

Alternate protein names: Glutamate/Cysteine Ligase; Glutamate-Cysteine Ligase GshA; Glutamate-Cysteine Ligase-Related Protein; Glutathione Synthetase; GshA Protein

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MTVIIDTLNDILTKYKLDIENWFFNKFTKYNPVLNISVDLRVSDYKIAPVDTNIFPAGYNNFTEQSQIYASRLLREYVVN
YANCSKILIIAENHTRNLKYIDSLIVLKNIVNNAGFVVEVGICNINQNIELISSTGRVINCLCLTNDNGVLRAGCRFIPD
LILVNNDMTSGIPEVLQGLKYQSIMPSLFLGWFNRSKSNHFSIYKKLSKEFCESFNIDPWLISAFFSSCSNICFFNSQGI
DDIANEVDVVISKIRNKFQLYSIKEQPYVFVKADNGTYGMGILVAYCGDDILMLNRKKRNKMKKIKDGNVVSSVIIQEGI
TTREIFNGYVAEPLVYFIGHTPSCYLYRYHSVKDRFSNLNSVGCDFIDISYKQQDILYWNIIGKIAVLAAAIEMHEISNV
NVMEQNCLLS

Sequences:

>Translated_410_residues
MTVIIDTLNDILTKYKLDIENWFFNKFTKYNPVLNISVDLRVSDYKIAPVDTNIFPAGYNNFTEQSQIYASRLLREYVVN
YANCSKILIIAENHTRNLKYIDSLIVLKNIVNNAGFVVEVGICNINQNIELISSTGRVINCLCLTNDNGVLRAGCRFIPD
LILVNNDMTSGIPEVLQGLKYQSIMPSLFLGWFNRSKSNHFSIYKKLSKEFCESFNIDPWLISAFFSSCSNICFFNSQGI
DDIANEVDVVISKIRNKFQLYSIKEQPYVFVKADNGTYGMGILVAYCGDDILMLNRKKRNKMKKIKDGNVVSSVIIQEGI
TTREIFNGYVAEPLVYFIGHTPSCYLYRYHSVKDRFSNLNSVGCDFIDISYKQQDILYWNIIGKIAVLAAAIEMHEISNV
NVMEQNCLLS
>Mature_409_residues
TVIIDTLNDILTKYKLDIENWFFNKFTKYNPVLNISVDLRVSDYKIAPVDTNIFPAGYNNFTEQSQIYASRLLREYVVNY
ANCSKILIIAENHTRNLKYIDSLIVLKNIVNNAGFVVEVGICNINQNIELISSTGRVINCLCLTNDNGVLRAGCRFIPDL
ILVNNDMTSGIPEVLQGLKYQSIMPSLFLGWFNRSKSNHFSIYKKLSKEFCESFNIDPWLISAFFSSCSNICFFNSQGID
DIANEVDVVISKIRNKFQLYSIKEQPYVFVKADNGTYGMGILVAYCGDDILMLNRKKRNKMKKIKDGNVVSSVIIQEGIT
TREIFNGYVAEPLVYFIGHTPSCYLYRYHSVKDRFSNLNSVGCDFIDISYKQQDILYWNIIGKIAVLAAAIEMHEISNVN
VMEQNCLLS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46766; Mature: 46634

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVIIDTLNDILTKYKLDIENWFFNKFTKYNPVLNISVDLRVSDYKIAPVDTNIFPAGYN
CEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECEEEEECCCCCCCCCCC
NFTEQSQIYASRLLREYVVNYANCSKILIIAENHTRNLKYIDSLIVLKNIVNNAGFVVEV
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEE
GICNINQNIELISSTGRVINCLCLTNDNGVLRAGCRFIPDLILVNNDMTSGIPEVLQGLK
EEEECCCCEEEEECCCCEEEEEEEECCCCEEECCHHHCCCEEEECCCCCCCHHHHHHCCC
YQSIMPSLFLGWFNRSKSNHFSIYKKLSKEFCESFNIDPWLISAFFSSCSNICFFNSQGI
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCCCH
DDIANEVDVVISKIRNKFQLYSIKEQPYVFVKADNGTYGMGILVAYCGDDILMLNRKKRN
HHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEECCCCCCCEEEEEEECCCEEEECCHHHH
KMKKIKDGNVVSSVIIQEGITTREIFNGYVAEPLVYFIGHTPSCYLYRYHSVKDRFSNLN
HHHHCCCCCHHHHHHHHCCCHHHHHHCCHHHHHHHEEECCCCCEEEEEEHHHHHHHCCCC
SVGCDFIDISYKQQDILYWNIIGKIAVLAAAIEMHEISNVNVMEQNCLLS
CCCCCEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
>Mature Secondary Structure 
TVIIDTLNDILTKYKLDIENWFFNKFTKYNPVLNISVDLRVSDYKIAPVDTNIFPAGYN
EEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECEEEEECCCCCCCCCCC
NFTEQSQIYASRLLREYVVNYANCSKILIIAENHTRNLKYIDSLIVLKNIVNNAGFVVEV
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEE
GICNINQNIELISSTGRVINCLCLTNDNGVLRAGCRFIPDLILVNNDMTSGIPEVLQGLK
EEEECCCCEEEEECCCCEEEEEEEECCCCEEECCHHHCCCEEEECCCCCCCHHHHHHCCC
YQSIMPSLFLGWFNRSKSNHFSIYKKLSKEFCESFNIDPWLISAFFSSCSNICFFNSQGI
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCCCH
DDIANEVDVVISKIRNKFQLYSIKEQPYVFVKADNGTYGMGILVAYCGDDILMLNRKKRN
HHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEECCCCCCCEEEEEEECCCEEEECCHHHH
KMKKIKDGNVVSSVIIQEGITTREIFNGYVAEPLVYFIGHTPSCYLYRYHSVKDRFSNLN
HHHHCCCCCHHHHHHHHCCCHHHHHHCCHHHHHHHEEECCCCCEEEEEEHHHHHHHCCCC
SVGCDFIDISYKQQDILYWNIIGKIAVLAAAIEMHEISNVNVMEQNCLLS
CCCCCEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA