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The map label for this gene is yaeL [C]

Identifier: 88658328

GI number: 88658328

Start: 1098742

End: 1099884

Strand: Direct

Name: yaeL [C]

Synonym: ECH_1070

Alternate gene names: 88658328

Gene position: 1098742-1099884 (Clockwise)

Preceding gene: 88657866

Following gene: 88658234

Centisome position: 93.41

GC content: 34.12

Gene sequence:

>1143_bases
ATGGCAAGTATTATTGATAACTTATATCATGTACTCAATAATGGTTCATTTTATTTGCTGTCGTTTCTCATTATAATGTC
TATTATAGTTTTCGTACATGAATACGGTCATTATATTGTTGCAAAATTATGCAATGTGAAGGTTGAAGTTTTTTCTATAG
GATTTGGCCCAGAGTTATTTGGAATTAACGATAAGTCTGGCACAAGGTGGAAGTTCAGCGTGATACCAATAGGTGGGTAT
GTAAAGATGTTAGGGGATGAAGACCCAGCAAGTGTTGAAGCAAATCCTAACCGTTTGTCAGAAGAAGATAAGTTACTTGC
ATTTTGTGAAAAACCTCTATACCAAAAATTTCTTATTGTATTTGCTGGACCATTCGCAAATTTAGTGTTTGCTATAGTAG
TACTCATGATGTTCTTCACTACTAAAGGAATGATGAAGCACAACTCTGTCATTGGAGGCGTAGTACAAGATAGTGCAGCA
CAACATGCAGGATTAGCTTCAGGGGATACAATTCTAAAAATCAACGACTACCAGGTTAAATGGTTTGAAGAAATTAAACA
GTATATAGAAAAATATGCAAAAGATAATCAAGAGCTAACTATAGAATATGCACGTGACGGGCACATTCATGTTGTGAAAG
TTAAACCAAGCATTAAGGAAGAAAAAGGACTTTTTGGAAGCATAAAGAAAAGTCCATTTTTAGGAGTTACAATGAGTAAT
GTACTCAGCAATTATGAATTTCAGAGATTAAGCATCACTAGTGCTTTTGTTCAGTCCATTAATTACACTTATTTACTGTC
AAAGTCAATTTTTCAAGTATTGGGACAAATGTTGGTAGGGAAACGCAGTATTTCTGAGTTAGGTGGTCCTATACGCATTG
CTCAATATTCTGGAGAATCAGTAAAACACAACGAAGTACTATTGTGCATGGCAATGATTTCCATTAACCTAGGTGTAATG
AATTTATTACCAATTCCTATGCTAGATGGTGGACATATTTTCCAATATTTTGTCCAAGCTATATTACGACGCAAACAACT
CAATCCTAAATATCAGCGGTATATATCTACAATTGGGTTAATGCTTCTGCTATCTTTAATGATTTTTGTCACGTTTAACG
ATATAAAAAGTATGTTTAAGTAG

Upstream 100 bases:

>100_bases
TTTCAAATTGTCTAATTAAAATTATTACATATTATGTTGTCAACCATATAAATATACTATATTATCCAATTTAGTTTTAA
TGACATCTAGTGTTCTACTT

Downstream 100 bases:

>100_bases
TTTTATGAGATACATTATTATTATTTTAATATTATTTACTTCTTCTCTTGCACATGCAGAGGCTTTAAATACTAAAATTA
AGCAAGTTCAAATCAATGGC

Product: putative membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MASIIDNLYHVLNNGSFYLLSFLIIMSIIVFVHEYGHYIVAKLCNVKVEVFSIGFGPELFGINDKSGTRWKFSVIPIGGY
VKMLGDEDPASVEANPNRLSEEDKLLAFCEKPLYQKFLIVFAGPFANLVFAIVVLMMFFTTKGMMKHNSVIGGVVQDSAA
QHAGLASGDTILKINDYQVKWFEEIKQYIEKYAKDNQELTIEYARDGHIHVVKVKPSIKEEKGLFGSIKKSPFLGVTMSN
VLSNYEFQRLSITSAFVQSINYTYLLSKSIFQVLGQMLVGKRSISELGGPIRIAQYSGESVKHNEVLLCMAMISINLGVM
NLLPIPMLDGGHIFQYFVQAILRRKQLNPKYQRYISTIGLMLLLSLMIFVTFNDIKSMFK

Sequences:

>Translated_380_residues
MASIIDNLYHVLNNGSFYLLSFLIIMSIIVFVHEYGHYIVAKLCNVKVEVFSIGFGPELFGINDKSGTRWKFSVIPIGGY
VKMLGDEDPASVEANPNRLSEEDKLLAFCEKPLYQKFLIVFAGPFANLVFAIVVLMMFFTTKGMMKHNSVIGGVVQDSAA
QHAGLASGDTILKINDYQVKWFEEIKQYIEKYAKDNQELTIEYARDGHIHVVKVKPSIKEEKGLFGSIKKSPFLGVTMSN
VLSNYEFQRLSITSAFVQSINYTYLLSKSIFQVLGQMLVGKRSISELGGPIRIAQYSGESVKHNEVLLCMAMISINLGVM
NLLPIPMLDGGHIFQYFVQAILRRKQLNPKYQRYISTIGLMLLLSLMIFVTFNDIKSMFK
>Mature_379_residues
ASIIDNLYHVLNNGSFYLLSFLIIMSIIVFVHEYGHYIVAKLCNVKVEVFSIGFGPELFGINDKSGTRWKFSVIPIGGYV
KMLGDEDPASVEANPNRLSEEDKLLAFCEKPLYQKFLIVFAGPFANLVFAIVVLMMFFTTKGMMKHNSVIGGVVQDSAAQ
HAGLASGDTILKINDYQVKWFEEIKQYIEKYAKDNQELTIEYARDGHIHVVKVKPSIKEEKGLFGSIKKSPFLGVTMSNV
LSNYEFQRLSITSAFVQSINYTYLLSKSIFQVLGQMLVGKRSISELGGPIRIAQYSGESVKHNEVLLCMAMISINLGVMN
LLPIPMLDGGHIFQYFVQAILRRKQLNPKYQRYISTIGLMLLLSLMIFVTFNDIKSMFK

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=186, Percent_Identity=34.4086021505376, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 42858; Mature: 42727

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIIDNLYHVLNNGSFYLLSFLIIMSIIVFVHEYGHYIVAKLCNVKVEVFSIGFGPELF
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEE
GINDKSGTRWKFSVIPIGGYVKMLGDEDPASVEANPNRLSEEDKLLAFCEKPLYQKFLIV
ECCCCCCCEEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
FAGPFANLVFAIVVLMMFFTTKGMMKHNSVIGGVVQDSAAQHAGLASGDTILKINDYQVK
HCCHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHH
WFEEIKQYIEKYAKDNQELTIEYARDGHIHVVKVKPSIKEEKGLFGSIKKSPFLGVTMSN
HHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCCCCHHCCCCCCCCCCCCCCEEHHH
VLSNYEFQRLSITSAFVQSINYTYLLSKSIFQVLGQMLVGKRSISELGGPIRIAQYSGES
HHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCCEEEEECCCCC
VKHNEVLLCMAMISINLGVMNLLPIPMLDGGHIFQYFVQAILRRKQLNPKYQRYISTIGL
CCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
MLLLSLMIFVTFNDIKSMFK
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASIIDNLYHVLNNGSFYLLSFLIIMSIIVFVHEYGHYIVAKLCNVKVEVFSIGFGPELF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEE
GINDKSGTRWKFSVIPIGGYVKMLGDEDPASVEANPNRLSEEDKLLAFCEKPLYQKFLIV
ECCCCCCCEEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
FAGPFANLVFAIVVLMMFFTTKGMMKHNSVIGGVVQDSAAQHAGLASGDTILKINDYQVK
HCCHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHH
WFEEIKQYIEKYAKDNQELTIEYARDGHIHVVKVKPSIKEEKGLFGSIKKSPFLGVTMSN
HHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCCCCHHCCCCCCCCCCCCCCEEHHH
VLSNYEFQRLSITSAFVQSINYTYLLSKSIFQVLGQMLVGKRSISELGGPIRIAQYSGES
HHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCCEEEEECCCCC
VKHNEVLLCMAMISINLGVMNLLPIPMLDGGHIFQYFVQAILRRKQLNPKYQRYISTIGL
CCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
MLLLSLMIFVTFNDIKSMFK
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]