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The map label for this gene is dacC [H]

Identifier: 88657866

GI number: 88657866

Start: 1095119

End: 1096264

Strand: Direct

Name: dacC [H]

Synonym: ECH_1067

Alternate gene names: 88657866

Gene position: 1095119-1096264 (Clockwise)

Preceding gene: 88658049

Following gene: 88658328

Centisome position: 93.1

GC content: 33.68

Gene sequence:

>1146_bases
ATGTTACGCCATATAATCCTTCTACTGTTATATTGTTTTATTAGTATTCAGGTACATATAAGTAATGCTGTGGCCTTACC
TATACAAACAACAGCACCTCAAGCAGCAGTATTCGATTTCTTTTCTAATACAATGTTATTAGAACACAACATTGACGAAC
AAATTGCACCCTCGTCTATGACTAACTTAATGACCTTATATGTTACATTTTACTACATAAAAGCTGGATTTGTAAAAATG
GAGGATAAATTTAAGACTAGTAAAGAGGCTTGGCAGAAAGGAGGTAACTCCATTTTCCTAAGGGCGGGACAGCTAGTAGC
AGTAAGAGATTTAATTAATGGTATTATTACAACATCTGCAAATGACGCCTGTATTACTCTTGCAGAAGGCGTAGCAGGTT
CACAGGAGAACTTTGTTGATGAAATGAATCGTATAGCACAAAAACTTAACCTAACAAAATCTCATTTCAGCAATGTAATA
GGTGCTCAAGATAAAAATCAATTCATGTCAATACGCGACTTAATAACTCTTACAGTAAGAATTTTCGAAGATTTTCCTGA
ATATTATCATCTATTCTCCAAAAAAGATTTTAAGTACAATAATATATACCAAGAAAACATCAACTTATTGTCACCAGATA
ATAGAATAGATGGGATAATTAGCATATATACAGATGCAGGAGGATACGGGTCTATAGTAGCTGCTAAACATGAAGGCAGA
CGTATCTTCATATTAATCAGCGGTCTTAAAACTGAAAAAGAACGCATATCTGAAATAAAGCAGTTGCTAGATTATGCTTT
TAATGATTTTAGCAGCCAAACCATCTTTCACAAAGGTAGTAAAGCCAAGGAAATAATAGTTAAAAACGGTGATGCAAAAT
ATGTAGAAGCTGTGTTCAATAACGATGTGATTATTCTATATCCTAAAGGCTCATATGATACAGTCAAAACCTTTTTTTCA
CACGAAAATGCAATATCTGCACCAGTAAAAAAAGGACAAGAAGTTGGTCATCTTCACATACAGGTACCAGAACTTACAGA
ACGCGTTATACCTATGTACGCAGCAAATGATATAAACCATCTCAATTTCTTCCAAAGAATATTGTACATGTTTTCCCCTA
AAACAGATAAAGTTGCTACTTCATAA

Upstream 100 bases:

>100_bases
TCTACTGACAGTTATCACAAAATATATTAAGCAATTATATATTGATCTAATACAAAGATTGATATATAAAAGCTCATAGG
TTCTCTGAAATATTTTTACA

Downstream 100 bases:

>100_bases
TGTACAGTCATAGTTCTAACTCATATCAAGTTTAAAGTTATATAATATGCATAAACAAACGCTGTGTTTATTAATGACTT
AAATCACATACTTTTATAAA

Product: D-alanyl-D-alanine carboxypeptidase family protein

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MLRHIILLLLYCFISIQVHISNAVALPIQTTAPQAAVFDFFSNTMLLEHNIDEQIAPSSMTNLMTLYVTFYYIKAGFVKM
EDKFKTSKEAWQKGGNSIFLRAGQLVAVRDLINGIITTSANDACITLAEGVAGSQENFVDEMNRIAQKLNLTKSHFSNVI
GAQDKNQFMSIRDLITLTVRIFEDFPEYYHLFSKKDFKYNNIYQENINLLSPDNRIDGIISIYTDAGGYGSIVAAKHEGR
RIFILISGLKTEKERISEIKQLLDYAFNDFSSQTIFHKGSKAKEIIVKNGDAKYVEAVFNNDVIILYPKGSYDTVKTFFS
HENAISAPVKKGQEVGHLHIQVPELTERVIPMYAANDINHLNFFQRILYMFSPKTDKVATS

Sequences:

>Translated_381_residues
MLRHIILLLLYCFISIQVHISNAVALPIQTTAPQAAVFDFFSNTMLLEHNIDEQIAPSSMTNLMTLYVTFYYIKAGFVKM
EDKFKTSKEAWQKGGNSIFLRAGQLVAVRDLINGIITTSANDACITLAEGVAGSQENFVDEMNRIAQKLNLTKSHFSNVI
GAQDKNQFMSIRDLITLTVRIFEDFPEYYHLFSKKDFKYNNIYQENINLLSPDNRIDGIISIYTDAGGYGSIVAAKHEGR
RIFILISGLKTEKERISEIKQLLDYAFNDFSSQTIFHKGSKAKEIIVKNGDAKYVEAVFNNDVIILYPKGSYDTVKTFFS
HENAISAPVKKGQEVGHLHIQVPELTERVIPMYAANDINHLNFFQRILYMFSPKTDKVATS
>Mature_381_residues
MLRHIILLLLYCFISIQVHISNAVALPIQTTAPQAAVFDFFSNTMLLEHNIDEQIAPSSMTNLMTLYVTFYYIKAGFVKM
EDKFKTSKEAWQKGGNSIFLRAGQLVAVRDLINGIITTSANDACITLAEGVAGSQENFVDEMNRIAQKLNLTKSHFSNVI
GAQDKNQFMSIRDLITLTVRIFEDFPEYYHLFSKKDFKYNNIYQENINLLSPDNRIDGIISIYTDAGGYGSIVAAKHEGR
RIFILISGLKTEKERISEIKQLLDYAFNDFSSQTIFHKGSKAKEIIVKNGDAKYVEAVFNNDVIILYPKGSYDTVKTFFS
HENAISAPVKKGQEVGHLHIQVPELTERVIPMYAANDINHLNFFQRILYMFSPKTDKVATS

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=340, Percent_Identity=33.5294117647059, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI87082022, Length=357, Percent_Identity=29.4117647058824, Blast_Score=175, Evalue=5e-45,
Organism=Escherichia coli, GI1786851, Length=384, Percent_Identity=31.5104166666667, Blast_Score=173, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 43160; Mature: 43160

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRHIILLLLYCFISIQVHISNAVALPIQTTAPQAAVFDFFSNTMLLEHNIDEQIAPSSM
CHHHHHHHHHHHHHEEEEEECCEEEEEEECCCCHHHHHHHHCCCEEEECCCCCCCCCHHH
TNLMTLYVTFYYIKAGFVKMEDKFKTSKEAWQKGGNSIFLRAGQLVAVRDLINGIITTSA
HHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHEECCC
NDACITLAEGVAGSQENFVDEMNRIAQKLNLTKSHFSNVIGAQDKNQFMSIRDLITLTVR
CCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IFEDFPEYYHLFSKKDFKYNNIYQENINLLSPDNRIDGIISIYTDAGGYGSIVAAKHEGR
HHHHHHHHHHHHCCCCCCCCCEECCCCCEECCCCCCCEEEEEEECCCCCCCEEEEEECCC
RIFILISGLKTEKERISEIKQLLDYAFNDFSSQTIFHKGSKAKEIIVKNGDAKYVEAVFN
EEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCHHHHHHHHC
NDVIILYPKGSYDTVKTFFSHENAISAPVKKGQEVGHLHIQVPELTERVIPMYAANDINH
CCEEEEEECCCHHHHHHHHHCCCCCCCHHHCCCCCCEEEEECHHHHHHHCCHHHCCCCHH
LNFFQRILYMFSPKTDKVATS
HHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLRHIILLLLYCFISIQVHISNAVALPIQTTAPQAAVFDFFSNTMLLEHNIDEQIAPSSM
CHHHHHHHHHHHHHEEEEEECCEEEEEEECCCCHHHHHHHHCCCEEEECCCCCCCCCHHH
TNLMTLYVTFYYIKAGFVKMEDKFKTSKEAWQKGGNSIFLRAGQLVAVRDLINGIITTSA
HHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHEECCC
NDACITLAEGVAGSQENFVDEMNRIAQKLNLTKSHFSNVIGAQDKNQFMSIRDLITLTVR
CCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IFEDFPEYYHLFSKKDFKYNNIYQENINLLSPDNRIDGIISIYTDAGGYGSIVAAKHEGR
HHHHHHHHHHHHCCCCCCCCCEECCCCCEECCCCCCCEEEEEEECCCCCCCEEEEEECCC
RIFILISGLKTEKERISEIKQLLDYAFNDFSSQTIFHKGSKAKEIIVKNGDAKYVEAVFN
EEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCHHHHHHHHC
NDVIILYPKGSYDTVKTFFSHENAISAPVKKGQEVGHLHIQVPELTERVIPMYAANDINH
CCEEEEEECCCHHHHHHHHHCCCCCCCHHHCCCCCCEEEEECHHHHHHHCCHHHCCCCHH
LNFFQRILYMFSPKTDKVATS
HHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]