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The map label for this gene is dsbD [H]

Identifier: 88657827

GI number: 88657827

Start: 1096827

End: 1098047

Strand: Reverse

Name: dsbD [H]

Synonym: ECH_1068

Alternate gene names: 88657827

Gene position: 1098047-1096827 (Counterclockwise)

Preceding gene: 88657579

Following gene: 88657661

Centisome position: 93.35

GC content: 29.48

Gene sequence:

>1221_bases
ATGTTTTTTAATGTTAATTCAATATACATTTTGATATGTGCTTTACTTGGCGGCATAATTTTAAATTGTATGCCATGTGT
ATTCCCTATCTTATCATTAAAAATAATGTCAATGGTTAAGAATGCTCAAAAGAGTAAAATATTGATAAGAGCTGATGGGG
TATTATATACACTTGGAGTTATGGTGAGTATGTTTCTACTGTCTTCAATACTTTTAATATTACGTCATTTTGGCTATTTA
GTAAGTTGGGGATATCAAATGCAATTTCCAATATTAATTGCATTGTTGATGTATATAATGTTTTTGATGGGATTATCTTT
TTCTGGATTTTATGATTTGCCTTTTATTGTTCCTAATTTTAATAATGTGAATTCTAAAAGAGAAGGATTAATAGGTAGTT
TTATTGTGGGTATGTTATCAACGTTTGTTGCTACCCCGTGTACAGCCCCTTTTATGGTATCTGCTGTAACTGTAGCTTTA
AATCAATCTAACCTTTACTCAGTGTTGATTTTTCAAGTTCTTGGTTTTGGAATTGCGTTGCCTTATTTATTATTGTCATT
TTTTCCAGGTTTATTGAAAATTATTCCTAAGCCAGGTAGATGGATGGAAGTTTTACAAAGATTTTTAGCTTTCCCACTTT
ATTTTTCTTCAGCGTGGTTACTCTGTATTTTAATCAAACAGAAAGGTCCGGAAATATTATTTGCTGTGTTATCTTGTGCT
ATATTATTTGTCATGGGGATATGGATTATGAAATTTATAAAATCTTGGGAACCTATAAGTAAGTTTGTAATTTGCTTGTG
TTTATTGTTTATAGCAATTTCTCCTTTATGTTTTGAGCCAATAAAAGAGTTTCTAATGAAACATAAGGAAGCAAAACATG
TTGTAGTAATGGAATTTTCTCAAAAGAAGTTAGAACAACTACTTGAAGCGAAAGAGACAGTATTGTTGTCTGTAAGTGCA
GATTGGTGTTTAACTTGTAAAGTTAATGAAAAAATTTTACAGTTGGACACTGTACAGGCTTTGCTTATGAAGAAAAAAAT
TTACTACATGAGAGGTGATTTAACTTCTAAAAATTATGAATTAACAGAGTATATTAATCAGTTGGATAAAAATAGTGTAC
CGCTTTATGTATTGTATGTTGATGGAGTTAAGATTAAAGTTTTACCACAAGTCCTCAGTGAAAAGATAGTAATTGATATT
ATAAACAAATATGTAAAATAG

Upstream 100 bases:

>100_bases
TTAATGTTAATAGTTTTTTAGGTATACAAACTTATAGTTGTCTTGTGTGCATTTTTTTAATTTAATAGTTAATGTTATAT
CCTTTTTAGAATATTTAAAT

Downstream 100 bases:

>100_bases
TAAGTTTTTTATTTGTTGATATTATAAATATTATTATATTCCTAGTTCTATGAAAGTTCTGTTACTTTATTTTTTATGCT
GTTAATGTTATTGTCTCGTT

Product: C-type cytochrome family protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MFFNVNSIYILICALLGGIILNCMPCVFPILSLKIMSMVKNAQKSKILIRADGVLYTLGVMVSMFLLSSILLILRHFGYL
VSWGYQMQFPILIALLMYIMFLMGLSFSGFYDLPFIVPNFNNVNSKREGLIGSFIVGMLSTFVATPCTAPFMVSAVTVAL
NQSNLYSVLIFQVLGFGIALPYLLLSFFPGLLKIIPKPGRWMEVLQRFLAFPLYFSSAWLLCILIKQKGPEILFAVLSCA
ILFVMGIWIMKFIKSWEPISKFVICLCLLFIAISPLCFEPIKEFLMKHKEAKHVVVMEFSQKKLEQLLEAKETVLLSVSA
DWCLTCKVNEKILQLDTVQALLMKKKIYYMRGDLTSKNYELTEYINQLDKNSVPLYVLYVDGVKIKVLPQVLSEKIVIDI
INKYVK

Sequences:

>Translated_406_residues
MFFNVNSIYILICALLGGIILNCMPCVFPILSLKIMSMVKNAQKSKILIRADGVLYTLGVMVSMFLLSSILLILRHFGYL
VSWGYQMQFPILIALLMYIMFLMGLSFSGFYDLPFIVPNFNNVNSKREGLIGSFIVGMLSTFVATPCTAPFMVSAVTVAL
NQSNLYSVLIFQVLGFGIALPYLLLSFFPGLLKIIPKPGRWMEVLQRFLAFPLYFSSAWLLCILIKQKGPEILFAVLSCA
ILFVMGIWIMKFIKSWEPISKFVICLCLLFIAISPLCFEPIKEFLMKHKEAKHVVVMEFSQKKLEQLLEAKETVLLSVSA
DWCLTCKVNEKILQLDTVQALLMKKKIYYMRGDLTSKNYELTEYINQLDKNSVPLYVLYVDGVKIKVLPQVLSEKIVIDI
INKYVK
>Mature_406_residues
MFFNVNSIYILICALLGGIILNCMPCVFPILSLKIMSMVKNAQKSKILIRADGVLYTLGVMVSMFLLSSILLILRHFGYL
VSWGYQMQFPILIALLMYIMFLMGLSFSGFYDLPFIVPNFNNVNSKREGLIGSFIVGMLSTFVATPCTAPFMVSAVTVAL
NQSNLYSVLIFQVLGFGIALPYLLLSFFPGLLKIIPKPGRWMEVLQRFLAFPLYFSSAWLLCILIKQKGPEILFAVLSCA
ILFVMGIWIMKFIKSWEPISKFVICLCLLFIAISPLCFEPIKEFLMKHKEAKHVVVMEFSQKKLEQLLEAKETVLLSVSA
DWCLTCKVNEKILQLDTVQALLMKKKIYYMRGDLTSKNYELTEYINQLDKNSVPLYVLYVDGVKIKVLPQVLSEKIVIDI
INKYVK

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=391, Percent_Identity=25.0639386189258, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 46198; Mature: 46198

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFNVNSIYILICALLGGIILNCMPCVFPILSLKIMSMVKNAQKSKILIRADGVLYTLGV
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHH
MVSMFLLSSILLILRHFGYLVSWGYQMQFPILIALLMYIMFLMGLSFSGFYDLPFIVPNF
HHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCC
NNVNSKREGLIGSFIVGMLSTFVATPCTAPFMVSAVTVALNQSNLYSVLIFQVLGFGIAL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
PYLLLSFFPGLLKIIPKPGRWMEVLQRFLAFPLYFSSAWLLCILIKQKGPEILFAVLSCA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ILFVMGIWIMKFIKSWEPISKFVICLCLLFIAISPLCFEPIKEFLMKHKEAKHVVVMEFS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEEEHHH
QKKLEQLLEAKETVLLSVSADWCLTCKVNEKILQLDTVQALLMKKKIYYMRGDLTSKNYE
HHHHHHHHHHHHHEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
LTEYINQLDKNSVPLYVLYVDGVKIKVLPQVLSEKIVIDIINKYVK
HHHHHHHHCCCCCCEEEEEECCEEEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFFNVNSIYILICALLGGIILNCMPCVFPILSLKIMSMVKNAQKSKILIRADGVLYTLGV
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHH
MVSMFLLSSILLILRHFGYLVSWGYQMQFPILIALLMYIMFLMGLSFSGFYDLPFIVPNF
HHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCC
NNVNSKREGLIGSFIVGMLSTFVATPCTAPFMVSAVTVALNQSNLYSVLIFQVLGFGIAL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
PYLLLSFFPGLLKIIPKPGRWMEVLQRFLAFPLYFSSAWLLCILIKQKGPEILFAVLSCA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ILFVMGIWIMKFIKSWEPISKFVICLCLLFIAISPLCFEPIKEFLMKHKEAKHVVVMEFS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEEEHHH
QKKLEQLLEAKETVLLSVSADWCLTCKVNEKILQLDTVQALLMKKKIYYMRGDLTSKNYE
HHHHHHHHHHHHHEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
LTEYINQLDKNSVPLYVLYVDGVKIKVLPQVLSEKIVIDIINKYVK
HHHHHHHHCCCCCCEEEEEECCEEEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA