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The map label for this gene is pqqL [C]

Identifier: 88608715

GI number: 88608715

Start: 810907

End: 812220

Strand: Reverse

Name: pqqL [C]

Synonym: NSE_0914

Alternate gene names: 88608715

Gene position: 812220-810907 (Counterclockwise)

Preceding gene: 88608487

Following gene: 88608659

Centisome position: 94.55

GC content: 42.69

Gene sequence:

>1314_bases
ATGAAGCAGCTTTTATCTTGTTTGCTCTGTGTTTTTTCATTTTTCTTTTTGAGCCTTGGGCATTCGAAAGGGGATGAGCG
TATCCATTATACACTGAATAATGGGTTGGATGTTTATTTGATAAGGGACACTTCTCTACCCATTGTGTCACATGTTCTGC
TTTATAAGGTTGGAGGTGCGAGCGATCCTAGGGGTAGTTCCGGGCTTGCACATTATCTAGAGCACCTAATGTTCAGAAGT
TCAAAGAATATTCCGAGTATTAGTAAGGAGATAAATGGATTGCGTTCTTTGTATAACGCGTTTACCTCTGATTATCATAC
GGTTTACCATCAACTTTTTCACAGAGACAAGTTAGAGAAAGTCATTCGTCTAGAGGCTGAGAGGATGCGGAATCTCGTGA
TTAGTGATGAAGCTGCAGGATTGGAACGCAAAATCGTGATAGAAGAGCGTAAAATGAGAGTAGACAACAAACCAGTTGTA
AAACTCGAAGAAGAGATGATGGCAGCATTTTATCGCAGTGAGACAAGTTGGAATGTTATAGGTTGGGAGGAGGAGCTTGT
GCTCTTCGATGCTGCACTGGCGCAAAGAATGTATAATGCGTGCTATCGGCCGTCGAATGCGGTACTTCTGATTCTTGGCG
ACATCGATGTCGATGAGGCAAAGAAATATGTAGAGAAGTATTACGGTGTCTTGACAAACTCGTCTTCCCGGTGGCGTTCG
TGTTTTGGTAGAGTTGTGGAACCAGCACACCATTCGGACATAGATGTCAGGATGATCAACGATAAGACAGAAGACAGGGC
TTTAATATACTTTTTTCCAGCGCCTAATGTTTCGGCTGAAGGGCATGCTGCGATGTTAGTAGCTTCTCAGGTATTAGCGG
GTGGTAAGACAAGTGTGCTGGGTATGGAGCTCATTCATAATCTCAGGCTCGCGCTCAATGTTTCGGTAGATTATGATTAT
CTCACTTTTCGTAAGGGGATTGTTGAAATAATTGTTACTCCACTGAATGCGGACGTGAAACTGGAAATTCTTGAGAAGAG
TGTTTCAGGTGTTATGTCGGAGGTTGTAAAAAACGGCATTGGTGCCGACGATATTGAAGCTGCAAAAATGACGCTGAAAG
TCTCCTTGATGGAAGCTTTGGATGGTTTCAATGCTAGAAGCATTAGTCACGTTGCTGCCTTGTCCGTAGGTGCTGATTTT
GATCACTTTCAGAAATTGGCAGAACGCGTATCAGCTGTAACGCCGGAACAAATTAACAGTGCGATTATGCAATTGATGAA
TGCAAAGAAAGTAATAGGGTACTTAGATAAATAG

Upstream 100 bases:

>100_bases
TTTTAATGTTGCTGATGCAGCGATTTTTCTTGGTGTTGTGTTTGTACTTTTTCATTCAACCAGTGAGAAAGTCGGTAGCA
TAAATTAGATAAGAAATATT

Downstream 100 bases:

>100_bases
ATATGCTTAGGGGTATTATCTTCGTTTTATTTTTCTTAGTGTGTGGGTTTTCTCATGCAGTTGATAGTCAGACCTTATTC
AAGATTACAGAAGTTGAGAG

Product: M16 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MKQLLSCLLCVFSFFFLSLGHSKGDERIHYTLNNGLDVYLIRDTSLPIVSHVLLYKVGGASDPRGSSGLAHYLEHLMFRS
SKNIPSISKEINGLRSLYNAFTSDYHTVYHQLFHRDKLEKVIRLEAERMRNLVISDEAAGLERKIVIEERKMRVDNKPVV
KLEEEMMAAFYRSETSWNVIGWEEELVLFDAALAQRMYNACYRPSNAVLLILGDIDVDEAKKYVEKYYGVLTNSSSRWRS
CFGRVVEPAHHSDIDVRMINDKTEDRALIYFFPAPNVSAEGHAAMLVASQVLAGGKTSVLGMELIHNLRLALNVSVDYDY
LTFRKGIVEIIVTPLNADVKLEILEKSVSGVMSEVVKNGIGADDIEAAKMTLKVSLMEALDGFNARSISHVAALSVGADF
DHFQKLAERVSAVTPEQINSAIMQLMNAKKVIGYLDK

Sequences:

>Translated_437_residues
MKQLLSCLLCVFSFFFLSLGHSKGDERIHYTLNNGLDVYLIRDTSLPIVSHVLLYKVGGASDPRGSSGLAHYLEHLMFRS
SKNIPSISKEINGLRSLYNAFTSDYHTVYHQLFHRDKLEKVIRLEAERMRNLVISDEAAGLERKIVIEERKMRVDNKPVV
KLEEEMMAAFYRSETSWNVIGWEEELVLFDAALAQRMYNACYRPSNAVLLILGDIDVDEAKKYVEKYYGVLTNSSSRWRS
CFGRVVEPAHHSDIDVRMINDKTEDRALIYFFPAPNVSAEGHAAMLVASQVLAGGKTSVLGMELIHNLRLALNVSVDYDY
LTFRKGIVEIIVTPLNADVKLEILEKSVSGVMSEVVKNGIGADDIEAAKMTLKVSLMEALDGFNARSISHVAALSVGADF
DHFQKLAERVSAVTPEQINSAIMQLMNAKKVIGYLDK
>Mature_437_residues
MKQLLSCLLCVFSFFFLSLGHSKGDERIHYTLNNGLDVYLIRDTSLPIVSHVLLYKVGGASDPRGSSGLAHYLEHLMFRS
SKNIPSISKEINGLRSLYNAFTSDYHTVYHQLFHRDKLEKVIRLEAERMRNLVISDEAAGLERKIVIEERKMRVDNKPVV
KLEEEMMAAFYRSETSWNVIGWEEELVLFDAALAQRMYNACYRPSNAVLLILGDIDVDEAKKYVEKYYGVLTNSSSRWRS
CFGRVVEPAHHSDIDVRMINDKTEDRALIYFFPAPNVSAEGHAAMLVASQVLAGGKTSVLGMELIHNLRLALNVSVDYDY
LTFRKGIVEIIVTPLNADVKLEILEKSVSGVMSEVVKNGIGADDIEAAKMTLKVSLMEALDGFNARSISHVAALSVGADF
DHFQKLAERVSAVTPEQINSAIMQLMNAKKVIGYLDK

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 49046; Mature: 49046

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLLSCLLCVFSFFFLSLGHSKGDERIHYTLNNGLDVYLIRDTSLPIVSHVLLYKVGGA
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHCCCC
SDPRGSSGLAHYLEHLMFRSSKNIPSISKEINGLRSLYNAFTSDYHTVYHQLFHRDKLEK
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIRLEAERMRNLVISDEAAGLERKIVIEERKMRVDNKPVVKLEEEMMAAFYRSETSWNVI
HHHHHHHHHHHEEECCCCCCCCCEEEEHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEE
GWEEELVLFDAALAQRMYNACYRPSNAVLLILGDIDVDEAKKYVEKYYGVLTNSSSRWRS
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHH
CFGRVVEPAHHSDIDVRMINDKTEDRALIYFFPAPNVSAEGHAAMLVASQVLAGGKTSVL
HHHHHCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHH
GMELIHNLRLALNVSVDYDYLTFRKGIVEIIVTPLNADVKLEILEKSVSGVMSEVVKNGI
HHHHHHCCEEEEEEEECCCHHHHHHHHHHEEEECCCCCEEHHHHHHHHHHHHHHHHHCCC
GADDIEAAKMTLKVSLMEALDGFNARSISHVAALSVGADFDHFQKLAERVSAVTPEQINS
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHH
AIMQLMNAKKVIGYLDK
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKQLLSCLLCVFSFFFLSLGHSKGDERIHYTLNNGLDVYLIRDTSLPIVSHVLLYKVGGA
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHCCCC
SDPRGSSGLAHYLEHLMFRSSKNIPSISKEINGLRSLYNAFTSDYHTVYHQLFHRDKLEK
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIRLEAERMRNLVISDEAAGLERKIVIEERKMRVDNKPVVKLEEEMMAAFYRSETSWNVI
HHHHHHHHHHHEEECCCCCCCCCEEEEHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEE
GWEEELVLFDAALAQRMYNACYRPSNAVLLILGDIDVDEAKKYVEKYYGVLTNSSSRWRS
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHH
CFGRVVEPAHHSDIDVRMINDKTEDRALIYFFPAPNVSAEGHAAMLVASQVLAGGKTSVL
HHHHHCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHH
GMELIHNLRLALNVSVDYDYLTFRKGIVEIIVTPLNADVKLEILEKSVSGVMSEVVKNGI
HHHHHHCCEEEEEEEECCCHHHHHHHHHHEEEECCCCCEEHHHHHHHHHHHHHHHHHCCC
GADDIEAAKMTLKVSLMEALDGFNARSISHVAALSVGADFDHFQKLAERVSAVTPEQINS
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHH
AIMQLMNAKKVIGYLDK
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]