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The map label for this gene is iolS [H]

Identifier: 87201184

GI number: 87201184

Start: 3387136

End: 3388131

Strand: Reverse

Name: iolS [H]

Synonym: Saro_3172

Alternate gene names: 87201184

Gene position: 3388131-3387136 (Counterclockwise)

Preceding gene: 87201185

Following gene: 87201182

Centisome position: 95.13

GC content: 65.46

Gene sequence:

>996_bases
ATGTCGATTCAGCGCCGCCCGATCAACGGACGCGAGACCAACCCCATTGGTCTGGGATGCATGTCGCTGAGCTGGGCCTA
TGGCGGCCGGCCGAGCGACGAGGACGGCATCCGCCTGCTCCAGCACGCCGTCGACATCGGCTACGATCATTTCGACACCG
CGCGGCTCTATGGTCTCGGCCACAACGAGACCCAGGTCGGGATCGCGCTCAAGGGCCGACGCGACAAGGTTTTCCTGGCC
TCGAAGATGGGCATCTTCGCCAGCGGCGACAAGCGCGGCATCGATTGCCACCCGGACACGATCCGCAGCGAACTCGAAGT
CTCGCTCAGGCTGCTCCAGACCGACCACATCGACCTCTACTACATGCACCGCCGCGATTTCACCGTGCCGATCGAGGATT
CGGTCGGCGCGATGGCCGACCTCGTGAAGGAGGGCAAGATCGGCGGCATCGGCCTGTCCGAAATGTCGGCTGACACGCTG
CGCAAGGCTTCGGCGGTCCACCCCATCGCCGCGATGCAGACCGAATATTCACCCTGGACCCGCCAGGCCGAAATCGCCGT
CCTCGAGGCCTGCCGCGAGCTTGGCACCACGTTCGTCGCCTTTTCGCCGGTCGCGCGCGGGGTTCTGGCCGATGGCGTGC
ACGATCCCGCCGCGCTCGAGGAAAAGGACATCCGGCGCGCCATGCCGCGCTTCATGGGCGACAACTGGCCCAGGAACTAC
GCGCTCGTCCGCCAGTTCAATGCCATCGCCGCTCGCGAAGGCGTGACCCCGGCGCAGCTTTCGCTCGCCTGGGTCCTGTC
GCGGGGCGAACACGTCGTTGCCATTCCCGGCACCGGCAAGATCGCTCACCTCGAAGAGAACATCGCACGCTGGGACTGGG
AAATCCCGGTTGCGGTCGCTGCCGAAGTCGATGCCCTGATCAACCAGCAGACCGTCGCCGGTCACCGCTATGCCGGGGTC
ATGCTGCCGACGATCGATACCGAGGATTTCGACTGA

Upstream 100 bases:

>100_bases
CGGTCGGGAGCGGCGCCGTTTTGCCGTGTTCGGCATGTGATTGGGCGTTGACCGGGGCCGCCTGCTCCTGCCATCGGCAC
GGCGGTCAAAGGAGATTGCA

Downstream 100 bases:

>100_bases
CCGGCGTTACGCCAGCTTCGCGGCGCGGTCGGCAAGGCGTTCGACCGCCGCCGCGTGGATGGCGGGGGCCGTAACCAGCA
GCCCGAAGGCGCGCGGGTCG

Product: aldo/keto reductase

Products: NA

Alternate protein names: AKR11A; Vegetative protein 147; VEG147 [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSIQRRPINGRETNPIGLGCMSLSWAYGGRPSDEDGIRLLQHAVDIGYDHFDTARLYGLGHNETQVGIALKGRRDKVFLA
SKMGIFASGDKRGIDCHPDTIRSELEVSLRLLQTDHIDLYYMHRRDFTVPIEDSVGAMADLVKEGKIGGIGLSEMSADTL
RKASAVHPIAAMQTEYSPWTRQAEIAVLEACRELGTTFVAFSPVARGVLADGVHDPAALEEKDIRRAMPRFMGDNWPRNY
ALVRQFNAIAAREGVTPAQLSLAWVLSRGEHVVAIPGTGKIAHLEENIARWDWEIPVAVAAEVDALINQQTVAGHRYAGV
MLPTIDTEDFD

Sequences:

>Translated_331_residues
MSIQRRPINGRETNPIGLGCMSLSWAYGGRPSDEDGIRLLQHAVDIGYDHFDTARLYGLGHNETQVGIALKGRRDKVFLA
SKMGIFASGDKRGIDCHPDTIRSELEVSLRLLQTDHIDLYYMHRRDFTVPIEDSVGAMADLVKEGKIGGIGLSEMSADTL
RKASAVHPIAAMQTEYSPWTRQAEIAVLEACRELGTTFVAFSPVARGVLADGVHDPAALEEKDIRRAMPRFMGDNWPRNY
ALVRQFNAIAAREGVTPAQLSLAWVLSRGEHVVAIPGTGKIAHLEENIARWDWEIPVAVAAEVDALINQQTVAGHRYAGV
MLPTIDTEDFD
>Mature_330_residues
SIQRRPINGRETNPIGLGCMSLSWAYGGRPSDEDGIRLLQHAVDIGYDHFDTARLYGLGHNETQVGIALKGRRDKVFLAS
KMGIFASGDKRGIDCHPDTIRSELEVSLRLLQTDHIDLYYMHRRDFTVPIEDSVGAMADLVKEGKIGGIGLSEMSADTLR
KASAVHPIAAMQTEYSPWTRQAEIAVLEACRELGTTFVAFSPVARGVLADGVHDPAALEEKDIRRAMPRFMGDNWPRNYA
LVRQFNAIAAREGVTPAQLSLAWVLSRGEHVVAIPGTGKIAHLEENIARWDWEIPVAVAAEVDALINQQTVAGHRYAGVM
LPTIDTEDFD

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI223718702, Length=276, Percent_Identity=31.1594202898551, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI41327764, Length=272, Percent_Identity=29.4117647058824, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI27436969, Length=330, Percent_Identity=27.2727272727273, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4504825, Length=330, Percent_Identity=27.2727272727273, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI41152114, Length=277, Percent_Identity=29.6028880866426, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI27436962, Length=297, Percent_Identity=27.6094276094276, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI27436964, Length=297, Percent_Identity=27.6094276094276, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI27436966, Length=297, Percent_Identity=27.6094276094276, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI24497577, Length=298, Percent_Identity=25.503355704698, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI5174391, Length=298, Percent_Identity=25.503355704698, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI27436971, Length=285, Percent_Identity=27.719298245614, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI223718708, Length=117, Percent_Identity=34.1880341880342, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1788070, Length=301, Percent_Identity=29.2358803986711, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87081735, Length=328, Percent_Identity=28.0487804878049, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788081, Length=269, Percent_Identity=30.1115241635688, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789199, Length=347, Percent_Identity=27.6657060518732, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789375, Length=274, Percent_Identity=25.9124087591241, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786400, Length=267, Percent_Identity=26.5917602996255, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17564128, Length=332, Percent_Identity=25.9036144578313, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6325384, Length=226, Percent_Identity=25.6637168141593, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323998, Length=301, Percent_Identity=25.2491694352159, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=317, Percent_Identity=24.9211356466877, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319958, Length=281, Percent_Identity=25.2669039145907, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322615, Length=242, Percent_Identity=23.5537190082645, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI45553081, Length=317, Percent_Identity=27.7602523659306, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI20129731, Length=341, Percent_Identity=28.1524926686217, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281366140, Length=280, Percent_Identity=27.8571428571429, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24657054, Length=341, Percent_Identity=24.9266862170088, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24663317, Length=328, Percent_Identity=25.9146341463415, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24646155, Length=159, Percent_Identity=29.559748427673, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36468; Mature: 36337

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQRRPINGRETNPIGLGCMSLSWAYGGRPSDEDGIRLLQHAVDIGYDHFDTARLYGLG
CCCCCCCCCCCCCCCEEEEHEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECC
HNETQVGIALKGRRDKVFLASKMGIFASGDKRGIDCHPDTIRSELEVSLRLLQTDHIDLY
CCCCEEEEEEECCCCEEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHHHEEEECCEEEE
YMHRRDFTVPIEDSVGAMADLVKEGKIGGIGLSEMSADTLRKASAVHPIAAMQTEYSPWT
EEECCCEEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCC
RQAEIAVLEACRELGTTFVAFSPVARGVLADGVHDPAALEEKDIRRAMPRFMGDNWPRNY
CHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHCCCCCCCH
ALVRQFNAIAAREGVTPAQLSLAWVLSRGEHVVAIPGTGKIAHLEENIARWDWEIPVAVA
HHHHHHHHHHHHCCCCHHHHHHEEEECCCCEEEEECCCCCEEHHHHHHHHCCCCCCEEHH
AEVDALINQQTVAGHRYAGVMLPTIDTEDFD
HHHHHHHCCHHHCCCEECEEEEECCCCCCCC
>Mature Secondary Structure 
SIQRRPINGRETNPIGLGCMSLSWAYGGRPSDEDGIRLLQHAVDIGYDHFDTARLYGLG
CCCCCCCCCCCCCCEEEEHEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECC
HNETQVGIALKGRRDKVFLASKMGIFASGDKRGIDCHPDTIRSELEVSLRLLQTDHIDLY
CCCCEEEEEEECCCCEEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHHHEEEECCEEEE
YMHRRDFTVPIEDSVGAMADLVKEGKIGGIGLSEMSADTLRKASAVHPIAAMQTEYSPWT
EEECCCEEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCC
RQAEIAVLEACRELGTTFVAFSPVARGVLADGVHDPAALEEKDIRRAMPRFMGDNWPRNY
CHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHCCCCCCCH
ALVRQFNAIAAREGVTPAQLSLAWVLSRGEHVVAIPGTGKIAHLEENIARWDWEIPVAVA
HHHHHHHHHHHHCCCCHHHHHHEEEECCCCEEEEECCCCCEEHHHHHHHHCCCCCCEEHH
AEVDALINQQTVAGHRYAGVMLPTIDTEDFD
HHHHHHHCCHHHCCCEECEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377; 9298659 [H]