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The map label for this gene is sucC

Identifier: 87201182

GI number: 87201182

Start: 3384930

End: 3386129

Strand: Reverse

Name: sucC

Synonym: Saro_3170

Alternate gene names: 87201182

Gene position: 3386129-3384930 (Counterclockwise)

Preceding gene: 87201184

Following gene: 87201181

Centisome position: 95.07

GC content: 63.25

Gene sequence:

>1200_bases
ATGAACGTCCATGAATACCAGGCCAAGGAACTGCTCGCGAAGTATGGTGTGGGCATCCCGGCAGGCATCGCCGCGCTGAC
GGTCGAGGAAGCCGTCGCCGCTGCCAAGCAGCTTCCCGGACCGCTTTACGTCGTCAAGGCGCAGATCCACGCCGGCGGCC
GCGGCAAGGGCAAGTTCAAGGAACTCCCCGCCGACGCCAAGGGCGGCGTGCGCCTCGCCAAGAGCATCGAGGAAGTCGAG
GCTTTCGCCAAGGAAATGCTCGGCAACACCCTCGTCACCGTGCAGACCGGTGAAGCCGGCAAGCAGGTCAACCGCCTCTA
CGTGACCGACGGCGTCGACATCGACAAGGAATACTACCTCTCGATGGTCGTCGATCGCGCCACCGGCCGCGTCGCGATCA
TCGTGTCGACCGAAGGCGGCATGGACATCGAGGAAGTCGCCCACTCGACCCCGGAAAAGATCGCCACCATCGTGATCGAT
CCCGCCGAAGGCTTCATGCCGCACCACGGCCGCGCCGTCGGTTTCGCGCTCAAGCTTTCGGGTGACCTGCTCAAGCAGGC
CGCCAAGATCGCCGAGCAGCTCTACACCGCCTTCGTCGCGCTCGACTGCTCGATGCTCGAAATCAACCCGCTGGTGCAGA
CCAAGGATGGCAACCTCCTCGTGCTCGACACCAAGATGAGCTTCGATTCGAACGCGCTCTATCGTCACCCCGATGTCGTC
GCCCTGCGCGACGAAACCGAGGAAGACCCGGCCGAGATCGAGGCCAGCAAGTACGACCTCGCCTACATCAAGCTCGACGG
CAACATCGGCTGCATGGTCAACGGCGCGGGCCTTGCCATGGCGACGATGGACATCATCAAGCTGAACGGCGAATTCCCGG
CGAACTTCCTCGACGTGGGCGGCGGCGCCAACAAGGAAAAGGTCACCGCAGCCTTCAAGATCATCCTCAAGGACCCGGCC
GTGAAGGGCATTCTCGTCAACATCTTCGGCGGGATCATGAAGTGCGACATCATCGCCGAGGGCATCGTTGCCGCGGCGAA
GGAAGTGAACCTCTCGGTTCCGCTGGTCGTTCGCCTCGAAGGCACCAACGTCCAGCAGGGCAAGGACATCCTCGCCAACT
CGGGCCTGCCGATCGTTCCCGCCAACGACCTCGGCGATGCCGCCAAGAAGATCGTTGCCGAAGTGCGCGCGGTCGCCTGA

Upstream 100 bases:

>100_bases
CTCAAAGCACCAACGGCGGTGCATACCTTTGCGCCAATGGCGGCGCGCCTGATGGCCGGTCGGGTTTTCCCACCGGGCCA
ATTCAAAGCGGGGATCACAC

Downstream 100 bases:

>100_bases
TCGCTTTGTGCGACTGACGATTCGAAGGGGGCGTCGGGCGACCGGCGCCCCTTTTGCGTTGTCGCAGCGCAGGGGGAAGA
TCCGGTCCCGGATTTTGCCG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MNVHEYQAKELLAKYGVGIPAGIAALTVEEAVAAAKQLPGPLYVVKAQIHAGGRGKGKFKELPADAKGGVRLAKSIEEVE
AFAKEMLGNTLVTVQTGEAGKQVNRLYVTDGVDIDKEYYLSMVVDRATGRVAIIVSTEGGMDIEEVAHSTPEKIATIVID
PAEGFMPHHGRAVGFALKLSGDLLKQAAKIAEQLYTAFVALDCSMLEINPLVQTKDGNLLVLDTKMSFDSNALYRHPDVV
ALRDETEEDPAEIEASKYDLAYIKLDGNIGCMVNGAGLAMATMDIIKLNGEFPANFLDVGGGANKEKVTAAFKIILKDPA
VKGILVNIFGGIMKCDIIAEGIVAAAKEVNLSVPLVVRLEGTNVQQGKDILANSGLPIVPANDLGDAAKKIVAEVRAVA

Sequences:

>Translated_399_residues
MNVHEYQAKELLAKYGVGIPAGIAALTVEEAVAAAKQLPGPLYVVKAQIHAGGRGKGKFKELPADAKGGVRLAKSIEEVE
AFAKEMLGNTLVTVQTGEAGKQVNRLYVTDGVDIDKEYYLSMVVDRATGRVAIIVSTEGGMDIEEVAHSTPEKIATIVID
PAEGFMPHHGRAVGFALKLSGDLLKQAAKIAEQLYTAFVALDCSMLEINPLVQTKDGNLLVLDTKMSFDSNALYRHPDVV
ALRDETEEDPAEIEASKYDLAYIKLDGNIGCMVNGAGLAMATMDIIKLNGEFPANFLDVGGGANKEKVTAAFKIILKDPA
VKGILVNIFGGIMKCDIIAEGIVAAAKEVNLSVPLVVRLEGTNVQQGKDILANSGLPIVPANDLGDAAKKIVAEVRAVA
>Mature_399_residues
MNVHEYQAKELLAKYGVGIPAGIAALTVEEAVAAAKQLPGPLYVVKAQIHAGGRGKGKFKELPADAKGGVRLAKSIEEVE
AFAKEMLGNTLVTVQTGEAGKQVNRLYVTDGVDIDKEYYLSMVVDRATGRVAIIVSTEGGMDIEEVAHSTPEKIATIVID
PAEGFMPHHGRAVGFALKLSGDLLKQAAKIAEQLYTAFVALDCSMLEINPLVQTKDGNLLVLDTKMSFDSNALYRHPDVV
ALRDETEEDPAEIEASKYDLAYIKLDGNIGCMVNGAGLAMATMDIIKLNGEFPANFLDVGGGANKEKVTAAFKIILKDPA
VKGILVNIFGGIMKCDIIAEGIVAAAKEVNLSVPLVVRLEGTNVQQGKDILANSGLPIVPANDLGDAAKKIVAEVRAVA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=48.9637305699482, Blast_Score=350, Evalue=1e-96,
Organism=Homo sapiens, GI11321583, Length=392, Percent_Identity=46.1734693877551, Blast_Score=347, Evalue=1e-95,
Organism=Homo sapiens, GI294862256, Length=366, Percent_Identity=47.5409836065574, Blast_Score=323, Evalue=1e-88,
Organism=Escherichia coli, GI1786948, Length=395, Percent_Identity=53.1645569620253, Blast_Score=400, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=45.0632911392405, Blast_Score=337, Evalue=6e-93,
Organism=Caenorhabditis elegans, GI17567829, Length=391, Percent_Identity=45.2685421994885, Blast_Score=337, Evalue=9e-93,
Organism=Saccharomyces cerevisiae, GI6321683, Length=395, Percent_Identity=46.8354430379747, Blast_Score=363, Evalue=1e-101,
Organism=Drosophila melanogaster, GI21356231, Length=394, Percent_Identity=50, Blast_Score=370, Evalue=1e-103,
Organism=Drosophila melanogaster, GI161078106, Length=388, Percent_Identity=46.3917525773196, Blast_Score=325, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24645208, Length=388, Percent_Identity=46.3917525773196, Blast_Score=325, Evalue=2e-89,
Organism=Drosophila melanogaster, GI281361397, Length=389, Percent_Identity=46.5295629820051, Blast_Score=324, Evalue=7e-89,
Organism=Drosophila melanogaster, GI281361395, Length=389, Percent_Identity=46.5295629820051, Blast_Score=324, Evalue=7e-89,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_NOVAD (Q2G3G8)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_498439.1
- HSSP:   P53590
- ProteinModelPortal:   Q2G3G8
- SMR:   Q2G3G8
- STRING:   Q2G3G8
- GeneID:   3918212
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_3170
- NMPDR:   fig|48935.1.peg.2700
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   TDRVTLM
- PhylomeDB:   Q2G3G8
- ProtClustDB:   PRK00696
- BioCyc:   NARO279238:SARO_3170-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42247; Mature: 42247

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVHEYQAKELLAKYGVGIPAGIAALTVEEAVAAAKQLPGPLYVVKAQIHAGGRGKGKFK
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHH
ELPADAKGGVRLAKSIEEVEAFAKEMLGNTLVTVQTGEAGKQVNRLYVTDGVDIDKEYYL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEECCCCCCHHHHH
SMVVDRATGRVAIIVSTEGGMDIEEVAHSTPEKIATIVIDPAEGFMPHHGRAVGFALKLS
HHEEECCCCCEEEEEECCCCCCHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEEEEEEEC
GDLLKQAAKIAEQLYTAFVALDCSMLEINPLVQTKDGNLLVLDTKMSFDSNALYRHPDVV
HHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEECCCCEEEEEECCCCCCCCEEECCCEE
ALRDETEEDPAEIEASKYDLAYIKLDGNIGCMVNGAGLAMATMDIIKLNGEFPANFLDVG
EECCCCCCCCCCEECCCEEEEEEEECCCEEEEEECCCCEEEEEEEEEECCCCCCCEEECC
GGANKEKVTAAFKIILKDPAVKGILVNIFGGIMKCDIIAEGIVAAAKEVNLSVPLVVRLE
CCCCHHHHEEEEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
GTNVQQGKDILANSGLPIVPANDLGDAAKKIVAEVRAVA
CCCCCCCCHHHHCCCCCEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNVHEYQAKELLAKYGVGIPAGIAALTVEEAVAAAKQLPGPLYVVKAQIHAGGRGKGKFK
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHH
ELPADAKGGVRLAKSIEEVEAFAKEMLGNTLVTVQTGEAGKQVNRLYVTDGVDIDKEYYL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEECCCCCCHHHHH
SMVVDRATGRVAIIVSTEGGMDIEEVAHSTPEKIATIVIDPAEGFMPHHGRAVGFALKLS
HHEEECCCCCEEEEEECCCCCCHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEEEEEEEC
GDLLKQAAKIAEQLYTAFVALDCSMLEINPLVQTKDGNLLVLDTKMSFDSNALYRHPDVV
HHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEECCCCEEEEEECCCCCCCCEEECCCEE
ALRDETEEDPAEIEASKYDLAYIKLDGNIGCMVNGAGLAMATMDIIKLNGEFPANFLDVG
EECCCCCCCCCCEECCCEEEEEEEECCCEEEEEECCCCEEEEEEEEEECCCCCCCEEECC
GGANKEKVTAAFKIILKDPAVKGILVNIFGGIMKCDIIAEGIVAAAKEVNLSVPLVVRLE
CCCCHHHHEEEEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
GTNVQQGKDILANSGLPIVPANDLGDAAKKIVAEVRAVA
CCCCCCCCHHHHCCCCCEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA