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The map label for this gene is fucO [H]

Identifier: 87200808

GI number: 87200808

Start: 3019067

End: 3020224

Strand: Reverse

Name: fucO [H]

Synonym: Saro_2795

Alternate gene names: 87200808

Gene position: 3020224-3019067 (Counterclockwise)

Preceding gene: 87200809

Following gene: 87200807

Centisome position: 84.8

GC content: 67.88

Gene sequence:

>1158_bases
ATGGCGGCAATCAATCTTCCCCGCGTGATCCGGGCTGGCGGCGGTGCGCTGGCCGAACTGCCCGATGCAATGGCGCAGTG
CGGCCTTTCGCGCCCCTTCGTGGTGACCGACGCGTTCCTCGTGCAGAGCGGGATGGTCGCGCGGATGCTCGAGGTGCTGG
ACGGCGCTGGGATTGCGGCCACGGTCTTCGATGCGACGGTGCCCGATCCGACGGTTGCGGTGGTCGAACAGGCGCTTGGC
GCGCTGCGCGAGGCGGAGTGCGATTGCGTGATCGGGTTCGGCGGGGGCAGCCCGATCGACACCTCGAAGGCCATCGCCGC
CCTGGCGCTGGAGCCGCGCGCGGTGCAATCGATGAAGGCGCCGGCGACGACCGACGTCCCGGGGCTGCCGATCATCGCCG
TCCCGACGACCGCGGGCACCGGCTCGGAGGCGACGAAGTTCACCATCGTGACCGATGAGGCGACGAGCGAGAAGATGCTC
TGCGCGGGCCTGGCCTTCCTGCCGACCATCGCCATCGTCGATTTCGAGCTGACCATGGGCAAGCCGGCGCGGCTAACTGC
CGACACCGGCATCGATTCGCTGACCCATGCGATCGAGGCCTATGTTTCGAAGAAGGCCAATCCGTTTTCGGATGCGATGG
CGATCTCGGCGATGAAGCTGATCGCGCCGAACATCCGCACCGCCTGCGCCGAACCCGGAAACCGGGCGGCGCGCGAGGCG
ATGATGATTGGCGCGCACCATGCCGGTATCGCGTTTTCCAACGCGAGCGTGGCGCTGGTGCACGGGATGAGCCGCCCCAT
CGGCGCGTTCTTTCATGTGCCGCACGGACTTTCCAACGCGATGTTGCTGCCTGCGATCACCGCGTTTTCCGCTCCGTCGG
CGCTGCCACGCTATGCCGATTGCGCCCGCGCGATGGGGGTGGCTTTGGAAAGCGAGGGCGACCAGTCGGCGGTGGCGCGG
CTGCTCGACGAGCTGGCGGCGCTGAACGCGGACCTTTCGGTCCCGACGCCGCAGTCGCATGGGATCAGCGCGGACCGCTG
GTTCGAGGTCGTGCCGGAAATGGCGCGGCAGGCGATCGCGTCAGGCTCGCCCGGCAATAATCCCCGCGTGCCTGATGCGG
CGGAAATCGAGCGGCTCTATGCCGAGGTCTTTGGCTGA

Upstream 100 bases:

>100_bases
GCCCTCCGAAGTGCAGGACATGCAGGGCCGCTGATCCTTTGGACGGTTGCGGAACCGCGCGGCCTGTAGTGATCTGCCGG
GCAGAGAAACGAGAGGACCA

Downstream 100 bases:

>100_bases
TCGGGGCGACGGCCTGGTCCGGGATATGGTTAAGCATTTCGCAAAGGCTGCGCGGTAGATCCATCCGGCACGGCGGGGAG
CGACCCTGCCGAAGGAGCAC

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: Propanediol oxidoreductase [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MAAINLPRVIRAGGGALAELPDAMAQCGLSRPFVVTDAFLVQSGMVARMLEVLDGAGIAATVFDATVPDPTVAVVEQALG
ALREAECDCVIGFGGGSPIDTSKAIAALALEPRAVQSMKAPATTDVPGLPIIAVPTTAGTGSEATKFTIVTDEATSEKML
CAGLAFLPTIAIVDFELTMGKPARLTADTGIDSLTHAIEAYVSKKANPFSDAMAISAMKLIAPNIRTACAEPGNRAAREA
MMIGAHHAGIAFSNASVALVHGMSRPIGAFFHVPHGLSNAMLLPAITAFSAPSALPRYADCARAMGVALESEGDQSAVAR
LLDELAALNADLSVPTPQSHGISADRWFEVVPEMARQAIASGSPGNNPRVPDAAEIERLYAEVFG

Sequences:

>Translated_385_residues
MAAINLPRVIRAGGGALAELPDAMAQCGLSRPFVVTDAFLVQSGMVARMLEVLDGAGIAATVFDATVPDPTVAVVEQALG
ALREAECDCVIGFGGGSPIDTSKAIAALALEPRAVQSMKAPATTDVPGLPIIAVPTTAGTGSEATKFTIVTDEATSEKML
CAGLAFLPTIAIVDFELTMGKPARLTADTGIDSLTHAIEAYVSKKANPFSDAMAISAMKLIAPNIRTACAEPGNRAAREA
MMIGAHHAGIAFSNASVALVHGMSRPIGAFFHVPHGLSNAMLLPAITAFSAPSALPRYADCARAMGVALESEGDQSAVAR
LLDELAALNADLSVPTPQSHGISADRWFEVVPEMARQAIASGSPGNNPRVPDAAEIERLYAEVFG
>Mature_384_residues
AAINLPRVIRAGGGALAELPDAMAQCGLSRPFVVTDAFLVQSGMVARMLEVLDGAGIAATVFDATVPDPTVAVVEQALGA
LREAECDCVIGFGGGSPIDTSKAIAALALEPRAVQSMKAPATTDVPGLPIIAVPTTAGTGSEATKFTIVTDEATSEKMLC
AGLAFLPTIAIVDFELTMGKPARLTADTGIDSLTHAIEAYVSKKANPFSDAMAISAMKLIAPNIRTACAEPGNRAAREAM
MIGAHHAGIAFSNASVALVHGMSRPIGAFFHVPHGLSNAMLLPAITAFSAPSALPRYADCARAMGVALESEGDQSAVARL
LDELAALNADLSVPTPQSHGISADRWFEVVPEMARQAIASGSPGNNPRVPDAAEIERLYAEVFG

Specific function: Fucose metabolism; fourth step. [C]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=363, Percent_Identity=31.129476584022, Blast_Score=128, Evalue=7e-30,
Organism=Escherichia coli, GI1789163, Length=370, Percent_Identity=38.1081081081081, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI48994951, Length=330, Percent_Identity=39.3939393939394, Blast_Score=238, Evalue=6e-64,
Organism=Escherichia coli, GI87082107, Length=379, Percent_Identity=36.6754617414248, Blast_Score=224, Evalue=8e-60,
Organism=Escherichia coli, GI1787493, Length=410, Percent_Identity=34.390243902439, Blast_Score=205, Evalue=4e-54,
Organism=Escherichia coli, GI1789386, Length=296, Percent_Identity=25, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17537053, Length=371, Percent_Identity=28.0323450134771, Blast_Score=128, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6321181, Length=353, Percent_Identity=33.1444759206799, Blast_Score=195, Evalue=9e-51,
Organism=Drosophila melanogaster, GI24657991, Length=352, Percent_Identity=30.9659090909091, Blast_Score=118, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211
- InterPro:   IPR013460 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.77 [H]

Molecular weight: Translated: 39612; Mature: 39481

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAINLPRVIRAGGGALAELPDAMAQCGLSRPFVVTDAFLVQSGMVARMLEVLDGAGIAA
CCCCCCCHHHHCCCCCHHHHHHHHHHCCCCCCEEEHHHHHHHCCHHHHHHHHHCCCCCEE
TVFDATVPDPTVAVVEQALGALREAECDCVIGFGGGSPIDTSKAIAALALEPRAVQSMKA
EEEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCHHHHHHCC
PATTDVPGLPIIAVPTTAGTGSEATKFTIVTDEATSEKMLCAGLAFLPTIAIVDFELTMG
CCCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHEEEEEEEECC
KPARLTADTGIDSLTHAIEAYVSKKANPFSDAMAISAMKLIAPNIRTACAEPGNRAAREA
CCCEEEHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHH
MMIGAHHAGIAFSNASVALVHGMSRPIGAFFHVPHGLSNAMLLPAITAFSAPSALPRYAD
HHHCCHHCCEEECCCCEEEEECCCCCCHHHEECCCCCCCCHHHHHHHHHCCCCCCCHHHH
CARAMGVALESEGDQSAVARLLDELAALNADLSVPTPQSHGISADRWFEVVPEMARQAIA
HHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SGSPGNNPRVPDAAEIERLYAEVFG
CCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AAINLPRVIRAGGGALAELPDAMAQCGLSRPFVVTDAFLVQSGMVARMLEVLDGAGIAA
CCCCCCHHHHCCCCCHHHHHHHHHHCCCCCCEEEHHHHHHHCCHHHHHHHHHCCCCCEE
TVFDATVPDPTVAVVEQALGALREAECDCVIGFGGGSPIDTSKAIAALALEPRAVQSMKA
EEEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCHHHHHHCC
PATTDVPGLPIIAVPTTAGTGSEATKFTIVTDEATSEKMLCAGLAFLPTIAIVDFELTMG
CCCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHEEEEEEEECC
KPARLTADTGIDSLTHAIEAYVSKKANPFSDAMAISAMKLIAPNIRTACAEPGNRAAREA
CCCEEEHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHH
MMIGAHHAGIAFSNASVALVHGMSRPIGAFFHVPHGLSNAMLLPAITAFSAPSALPRYAD
HHHCCHHCCEEECCCCEEEEECCCCCCHHHEECCCCCCCCHHHHHHHHHCCCCCCCHHHH
CARAMGVALESEGDQSAVARLLDELAALNADLSVPTPQSHGISADRWFEVVPEMARQAIA
HHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SGSPGNNPRVPDAAEIERLYAEVFG
CCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]