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The map label for this gene is fnrL [H]

Identifier: 87200594

GI number: 87200594

Start: 2786581

End: 2787276

Strand: Reverse

Name: fnrL [H]

Synonym: Saro_2581

Alternate gene names: 87200594

Gene position: 2787276-2786581 (Counterclockwise)

Preceding gene: 87200595

Following gene: 87200591

Centisome position: 78.26

GC content: 65.09

Gene sequence:

>696_bases
ATGACTGCCTGCGATACATGCGTTGTGCGCAACCGGGCAATTTGCGCCGGTCTGGATAACCGCGAGATCGCGGCACTCAA
TACGTTGGGCCGCCGCCGGGCGGTTTCTGCGGGTGAACCGCTGATGTGGGAGGACGACGACTCGCTCCTCGTCGCCAACG
TGATCGAGGGCGTTCTCAAGCTGACGACCAGCACCGAGGACGGGCGAGAGCAGATCGTCGGCGTGGCCTATCCATCGGAT
TTCATCGGCCGGCCATTCGGCCAGACGAGCAGCGCGAGCGTTGTGGCGCTGACCGACGCGCGGGTCTGCGTGTTCTCGCG
CAACGACTTCGACCGTTTCGCGCGCGAGCATCCGGAGCTTGAACACAAGCTGCTGGAACGCACGCTCGCCGAACTCGACC
GTACCCGGTCGTGGATGATGCTGCTGGGCCGCAAGAACGCCTCGGAGAAGATCGCGACGTTCCTGCTGGAGATGTCGGAC
CGGCTGGCCGAGACGGGCTGCACCCCGGCGTTCGGCCCGGCCAAGCGCTTTTCGCTGCCGTTTTCGCGCCAGCAAGTGGC
CGACGTTCTGGGCCTGACGATCGAGACGGTGAGCCGGCAGTTCACCAAGCTCAAGAACGATGGCGTGATCGAACTGCCTT
CGCGGCGCGAGGTCGAGATCGTCAATCGCGGGGCTCTGGTCGCGCTGGCGGGTTGA

Upstream 100 bases:

>100_bases
CTGGCCGCCCTATTTTTTTGCCTGCAGTTCGATGCACTTGCCGGTAAAGCTGGAACATTCGCTGATTGCCGGAAATGCTC
CGCAATGATAACGAACCCCC

Downstream 100 bases:

>100_bases
GCCGGACCATCGGAAGCCGCAAGGAAAAGGCCGGCCCCGCGAGGGACCGGCCTTTCCTTTTTCCGGAACCGTCGGATCAG
AACGACTTGCGGACAGTCAT

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MTACDTCVVRNRAICAGLDNREIAALNTLGRRRAVSAGEPLMWEDDDSLLVANVIEGVLKLTTSTEDGREQIVGVAYPSD
FIGRPFGQTSSASVVALTDARVCVFSRNDFDRFAREHPELEHKLLERTLAELDRTRSWMMLLGRKNASEKIATFLLEMSD
RLAETGCTPAFGPAKRFSLPFSRQQVADVLGLTIETVSRQFTKLKNDGVIELPSRREVEIVNRGALVALAG

Sequences:

>Translated_231_residues
MTACDTCVVRNRAICAGLDNREIAALNTLGRRRAVSAGEPLMWEDDDSLLVANVIEGVLKLTTSTEDGREQIVGVAYPSD
FIGRPFGQTSSASVVALTDARVCVFSRNDFDRFAREHPELEHKLLERTLAELDRTRSWMMLLGRKNASEKIATFLLEMSD
RLAETGCTPAFGPAKRFSLPFSRQQVADVLGLTIETVSRQFTKLKNDGVIELPSRREVEIVNRGALVALAG
>Mature_230_residues
TACDTCVVRNRAICAGLDNREIAALNTLGRRRAVSAGEPLMWEDDDSLLVANVIEGVLKLTTSTEDGREQIVGVAYPSDF
IGRPFGQTSSASVVALTDARVCVFSRNDFDRFAREHPELEHKLLERTLAELDRTRSWMMLLGRKNASEKIATFLLEMSDR
LAETGCTPAFGPAKRFSLPFSRQQVADVLGLTIETVSRQFTKLKNDGVIELPSRREVEIVNRGALVALAG

Specific function: Anaerobic regulatory protein; transcriptional activator of hemA. Appears to regulate other genes [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=231, Percent_Identity=28.1385281385281, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25485; Mature: 25354

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTACDTCVVRNRAICAGLDNREIAALNTLGRRRAVSAGEPLMWEDDDSLLVANVIEGVLK
CCCCHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHH
LTTSTEDGREQIVGVAYPSDFIGRPFGQTSSASVVALTDARVCVFSRNDFDRFAREHPEL
HHCCCCCCHHHEEEEECCHHHHCCCCCCCCCCEEEEEECCEEEEEECCCHHHHHHHCCHH
EHKLLERTLAELDRTRSWMMLLGRKNASEKIATFLLEMSDRLAETGCTPAFGPAKRFSLP
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCC
FSRQQVADVLGLTIETVSRQFTKLKNDGVIELPSRREVEIVNRGALVALAG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEECCCEEEEECC
>Mature Secondary Structure 
TACDTCVVRNRAICAGLDNREIAALNTLGRRRAVSAGEPLMWEDDDSLLVANVIEGVLK
CCCHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHH
LTTSTEDGREQIVGVAYPSDFIGRPFGQTSSASVVALTDARVCVFSRNDFDRFAREHPEL
HHCCCCCCHHHEEEEECCHHHHCCCCCCCCCCEEEEEECCEEEEEECCCHHHHHHHCCHH
EHKLLERTLAELDRTRSWMMLLGRKNASEKIATFLLEMSDRLAETGCTPAFGPAKRFSLP
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCC
FSRQQVADVLGLTIETVSRQFTKLKNDGVIELPSRREVEIVNRGALVALAG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592416 [H]