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The map label for this gene is sdhB

Identifier: 87200336

GI number: 87200336

Start: 2466404

End: 2467186

Strand: Direct

Name: sdhB

Synonym: Saro_2322

Alternate gene names: 87200336

Gene position: 2466404-2467186 (Clockwise)

Preceding gene: 87200335

Following gene: 87200337

Centisome position: 69.25

GC content: 63.47

Gene sequence:

>783_bases
ATGGCGACCTTCTCGCTTCCGAAGAACTCCAAGATCACCGGCAAGGCCCGCCATCACGCGGCGGCCACCAACGGCAAGGT
CCGCAAGTTCAAGGTCTATCGTTACGATCCCGACAGCGGCGAAAATCCGCGCTACGACACGTTCGAGATCGATCTCGACC
AGTGCGGCCCGATGGTGCTCGATGCGCTCATCAAGATGAAGGGCGAGCAGGACCCGACCCTCACCTTCCGCCGTTCCTGC
CGCGAAGGCATCTGCGGTTCCTGCGCGATGAACATGAATGGCCGCAACGGCCTCGCCTGCACCACCGCAATCGAGGATCT
GTCGGGCGATATCCGCATCACCCCGCTGCCGCACATGGAAGTGATCAAGGACCTCGTCCCCGATTTCACGCACTTCTACG
CGCAGTACGCCTCGATCCGCCCCTGGCTGCAAACCGTCAGCCCCACGCCTTCGGGCAAGGAGCGCCTGCAGTCGCCCGAA
CAGCGCGAAAAGCTCGACGGCCTGTACGAGTGCATCCTGTGCGCATGCTGCTCCACCTCGTGCCCGAGCTACTGGTGGAA
TTCCGACAAGTTCCTTGGCCCCGCGATCCTGCTCCAGGCCTACCGCTGGCTGGCCGACAGCCGCGACGAGATGACCGGCG
AGCGGCTGGACGAGCTGGAAGATCCCTTCCGCCTCTATCGCTGCCACACCATCATGAACTGCGCCAACGTCTGCCCGAAG
GGCCTGTCGCCGGCGCGCGCGATTGCCGAAATCAAGAAGATGCAGGCCGAGCGTCTCGTCTGA

Upstream 100 bases:

>100_bases
CCTCTACCATTGGGCAGGAACCACCCTCTTGCCCCCCGCGCTGCAATCGCTAAGGACGACTCAGCAAGCCGCACGCCCAG
GCACAGGACAGGACAGAACG

Downstream 100 bases:

>100_bases
TCCGGTGAGCGAGGCAGCCTTCCGCTACGAACCAGCCGCGGATCACTCCGGCTGGTTCACCTGGAACCTCACCGACGAGA
CCCGGTTCAACGCCCAGGTA

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MATFSLPKNSKITGKARHHAAATNGKVRKFKVYRYDPDSGENPRYDTFEIDLDQCGPMVLDALIKMKGEQDPTLTFRRSC
REGICGSCAMNMNGRNGLACTTAIEDLSGDIRITPLPHMEVIKDLVPDFTHFYAQYASIRPWLQTVSPTPSGKERLQSPE
QREKLDGLYECILCACCSTSCPSYWWNSDKFLGPAILLQAYRWLADSRDEMTGERLDELEDPFRLYRCHTIMNCANVCPK
GLSPARAIAEIKKMQAERLV

Sequences:

>Translated_260_residues
MATFSLPKNSKITGKARHHAAATNGKVRKFKVYRYDPDSGENPRYDTFEIDLDQCGPMVLDALIKMKGEQDPTLTFRRSC
REGICGSCAMNMNGRNGLACTTAIEDLSGDIRITPLPHMEVIKDLVPDFTHFYAQYASIRPWLQTVSPTPSGKERLQSPE
QREKLDGLYECILCACCSTSCPSYWWNSDKFLGPAILLQAYRWLADSRDEMTGERLDELEDPFRLYRCHTIMNCANVCPK
GLSPARAIAEIKKMQAERLV
>Mature_259_residues
ATFSLPKNSKITGKARHHAAATNGKVRKFKVYRYDPDSGENPRYDTFEIDLDQCGPMVLDALIKMKGEQDPTLTFRRSCR
EGICGSCAMNMNGRNGLACTTAIEDLSGDIRITPLPHMEVIKDLVPDFTHFYAQYASIRPWLQTVSPTPSGKERLQSPEQ
REKLDGLYECILCACCSTSCPSYWWNSDKFLGPAILLQAYRWLADSRDEMTGERLDELEDPFRLYRCHTIMNCANVCPKG
LSPARAIAEIKKMQAERLV

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=245, Percent_Identity=66.530612244898, Blast_Score=348, Evalue=4e-96,
Organism=Escherichia coli, GI1786943, Length=234, Percent_Identity=58.974358974359, Blast_Score=285, Evalue=2e-78,
Organism=Escherichia coli, GI1790596, Length=227, Percent_Identity=34.8017621145374, Blast_Score=143, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI17533915, Length=253, Percent_Identity=57.7075098814229, Blast_Score=321, Evalue=2e-88,
Organism=Saccharomyces cerevisiae, GI6322987, Length=233, Percent_Identity=63.0901287553648, Blast_Score=313, Evalue=2e-86,
Organism=Drosophila melanogaster, GI17137106, Length=238, Percent_Identity=63.4453781512605, Blast_Score=333, Evalue=7e-92,
Organism=Drosophila melanogaster, GI24643156, Length=236, Percent_Identity=61.4406779661017, Blast_Score=314, Evalue=4e-86,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29399; Mature: 29268

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATFSLPKNSKITGKARHHAAATNGKVRKFKVYRYDPDSGENPRYDTFEIDLDQCGPMVL
CCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCEEEECHHHCCHHHH
DALIKMKGEQDPTLTFRRSCREGICGSCAMNMNGRNGLACTTAIEDLSGDIRITPLPHME
HHHHHHCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHCCCCEEECCCCHHH
VIKDLVPDFTHFYAQYASIRPWLQTVSPTPSGKERLQSPEQREKLDGLYECILCACCSTS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCC
CPSYWWNSDKFLGPAILLQAYRWLADSRDEMTGERLDELEDPFRLYRCHTIMNCANVCPK
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLSPARAIAEIKKMQAERLV
CCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATFSLPKNSKITGKARHHAAATNGKVRKFKVYRYDPDSGENPRYDTFEIDLDQCGPMVL
CCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCEEEECHHHCCHHHH
DALIKMKGEQDPTLTFRRSCREGICGSCAMNMNGRNGLACTTAIEDLSGDIRITPLPHME
HHHHHHCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHCCCCEEECCCCHHH
VIKDLVPDFTHFYAQYASIRPWLQTVSPTPSGKERLQSPEQREKLDGLYECILCACCSTS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCC
CPSYWWNSDKFLGPAILLQAYRWLADSRDEMTGERLDELEDPFRLYRCHTIMNCANVCPK
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLSPARAIAEIKKMQAERLV
CCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA