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The map label for this gene is coaX

Identifier: 87200299

GI number: 87200299

Start: 2426541

End: 2427323

Strand: Reverse

Name: coaX

Synonym: Saro_2285

Alternate gene names: 87200299

Gene position: 2427323-2426541 (Counterclockwise)

Preceding gene: 87200300

Following gene: 87200298

Centisome position: 68.15

GC content: 63.73

Gene sequence:

>783_bases
ATGCTTCTGGCGGTTGACGTCGGCAATACCAACATCGTTTTCGCGCTGTTCGAGGGGCGCGAAATCAAGTCGCGCTGGCG
CGTTGCCACCGATCCGCGCCGCACGGCCGACGAGTACGCGGTCTGGCTGCTGCAACTGATGCAGCTCCAGGGCTTCGATC
CGAAGGTGGTGAAGCAGATCCTGATTTCGACGGTCGTTCCGCGCGCCCTCCACAACCTCAGCGTGCTGGCGCAGAAGTAC
TTCGGGCTGGATCCGCTGATCGCCGGGCAGCCTCCGGTGGAGTGGGGCTTCGAGGCCGATGTCGACGAGCCCCGGTCGCT
TGGCGCGGACCGTGCGGTCAATGCCATTGCCGCCCATGCGAAGTACCCCGGTGACCTGATCGTGGTCGATTTCGGCACGG
CGACGACGTTCGACGTCGTCGACTTCAACGGTGCCTACAAGGGCGGGATCATTGCTCCGGGGATCAACCTGTCGCTCGAC
GCGCTGGTCAATGCCGCAGCCAAGCTGCCGCGCATCGCCATTGAGGCGCCGACGCGCACGAAAAGCGTGATCGGCCGCAA
TACCGAAGACCAGATGCACATCGGCGTCTTCTGGGGCTACGTTGCCATGATGGAAGGCCTCATCGCGCGGATGCGAGCCG
AGATTGGCCGCCCCGCGAAGGTCGTCGCGACCGGTGGACTTGCGGTACTTTTCGGCGACCATACCGACATATTCGATCAC
GTGGACACCGACCTTACGCTCGATGGCCTTGCGATCCTCGCGGAGCGGGTGACTGTCCAGTGA

Upstream 100 bases:

>100_bases
GCCTTCGGGGGTATAGACGAGGATGGCGTTGCCCTTATGCGCTTGGCGGACGGGTCGGTCCGTGCCATCCACGCGGGCGA
TATAGAAATGGTGGGCTCCC

Downstream 100 bases:

>100_bases
AGTCTGCCAAGGAACTGCTTTTCCTCGCCTTGGGTGGTTCGGGCGAGATCGGGATGAACGTCAACCTCTATTGCTGCGAC
GGCAAGTGGCTGATGGTCGA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLLAVDVGNTNIVFALFEGREIKSRWRVATDPRRTADEYAVWLLQLMQLQGFDPKVVKQILISTVVPRALHNLSVLAQKY
FGLDPLIAGQPPVEWGFEADVDEPRSLGADRAVNAIAAHAKYPGDLIVVDFGTATTFDVVDFNGAYKGGIIAPGINLSLD
ALVNAAAKLPRIAIEAPTRTKSVIGRNTEDQMHIGVFWGYVAMMEGLIARMRAEIGRPAKVVATGGLAVLFGDHTDIFDH
VDTDLTLDGLAILAERVTVQ

Sequences:

>Translated_260_residues
MLLAVDVGNTNIVFALFEGREIKSRWRVATDPRRTADEYAVWLLQLMQLQGFDPKVVKQILISTVVPRALHNLSVLAQKY
FGLDPLIAGQPPVEWGFEADVDEPRSLGADRAVNAIAAHAKYPGDLIVVDFGTATTFDVVDFNGAYKGGIIAPGINLSLD
ALVNAAAKLPRIAIEAPTRTKSVIGRNTEDQMHIGVFWGYVAMMEGLIARMRAEIGRPAKVVATGGLAVLFGDHTDIFDH
VDTDLTLDGLAILAERVTVQ
>Mature_260_residues
MLLAVDVGNTNIVFALFEGREIKSRWRVATDPRRTADEYAVWLLQLMQLQGFDPKVVKQILISTVVPRALHNLSVLAQKY
FGLDPLIAGQPPVEWGFEADVDEPRSLGADRAVNAIAAHAKYPGDLIVVDFGTATTFDVVDFNGAYKGGIIAPGINLSLD
ALVNAAAKLPRIAIEAPTRTKSVIGRNTEDQMHIGVFWGYVAMMEGLIARMRAEIGRPAKVVATGGLAVLFGDHTDIFDH
VDTDLTLDGLAILAERVTVQ

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_NOVAD (Q2G601)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_497556.1
- ProteinModelPortal:   Q2G601
- SMR:   Q2G601
- STRING:   Q2G601
- GeneID:   3916603
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_2285
- NMPDR:   fig|48935.1.peg.749
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13318
- BioCyc:   NARO279238:SARO_2285-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28217; Mature: 28217

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: ACT_SITE 110-110 BINDING 133-133 BINDING 188-188

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAVDVGNTNIVFALFEGREIKSRWRVATDPRRTADEYAVWLLQLMQLQGFDPKVVKQI
CEEEEEECCCEEEEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
LISTVVPRALHNLSVLAQKYFGLDPLIAGQPPVEWGFEADVDEPRSLGADRAVNAIAAHA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHC
KYPGDLIVVDFGTATTFDVVDFNGAYKGGIIAPGINLSLDALVNAAAKLPRIAIEAPTRT
CCCCCEEEEECCCCCEEEEEECCCCCCCCEECCCCCCCHHHHHHHHHHCCEEEEECCCCH
KSVIGRNTEDQMHIGVFWGYVAMMEGLIARMRAEIGRPAKVVATGGLAVLFGDHTDIFDH
HHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCCHHHHH
VDTDLTLDGLAILAERVTVQ
CCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLAVDVGNTNIVFALFEGREIKSRWRVATDPRRTADEYAVWLLQLMQLQGFDPKVVKQI
CEEEEEECCCEEEEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
LISTVVPRALHNLSVLAQKYFGLDPLIAGQPPVEWGFEADVDEPRSLGADRAVNAIAAHA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHC
KYPGDLIVVDFGTATTFDVVDFNGAYKGGIIAPGINLSLDALVNAAAKLPRIAIEAPTRT
CCCCCEEEEECCCCCEEEEEECCCCCCCCEECCCCCCCHHHHHHHHHHCCEEEEECCCCH
KSVIGRNTEDQMHIGVFWGYVAMMEGLIARMRAEIGRPAKVVATGGLAVLFGDHTDIFDH
HHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCCHHHHH
VDTDLTLDGLAILAERVTVQ
CCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA