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The map label for this gene is ppiD [H]

Identifier: 87200036

GI number: 87200036

Start: 2152601

End: 2154541

Strand: Direct

Name: ppiD [H]

Synonym: Saro_2020

Alternate gene names: 87200036

Gene position: 2152601-2154541 (Clockwise)

Preceding gene: 87200031

Following gene: 87200037

Centisome position: 60.44

GC content: 68.42

Gene sequence:

>1941_bases
ATGCTCGGCTTCTTCCGCTCGTTCCTCAAGTCCCGCATCGGCGTAGCAATCGCCCTGCTTTTCCTCGGCCTGATCGCGCT
CGCCTTTGCCAGCGCCGATGTCACCGGCAGCGGCTTCGGCGGCGTCGCCGGCGGGGACCGTGCCGCCAAGGTCGGCTCCG
GCCGCATCGGCACGGGCGAACTCGGCAAGGCACTGACCAGCGCGTTCGAGCAGGACCGCCAGAAGCAGCCCGGCCTGACC
ATGAAGCAGTTCCTCGACGGCGGCGGCCTCGAAGGCGTCCTGTCGGGCATGATCGACAGGCTGGCGCTTGCGGAATGGGG
CAAGAAGCACGGCCTCGCGGTCAGCGACCGCCTGGTCGACAGCGAGATCGTCAAGATCGGCGCGTTCCAGGGCCCTGACG
GCAAGTTCAGCCAGAAGGCCTATGAGCAACTCCTCGCCCAGCGCGGCCTTACGGACAAGGAAGTGCGCAACGACCTTGCA
CAGGGCCTGATGGCCCGCCAGCTTCTGCTGCCCGCCGCGTTCGGCGCGCAGATGCCGGCCGAAGCGGTCCTGCGCTATGC
CTCGCTGCTTACCGAAAAGCGCGTCGGCACGATCATTTCGGTCCCCTCGCTGGCCTTCGCGCCCGCCGGCGGCCCCGATG
ACAACGCCCTCGCCGCGTTCTACAACGCCAACAAGGGCCGCTACATGCAGCCCGAACGCCGCACGATCCGCTATGCGCTC
GTCGACGAGGCAACGCTCAAGAACGTGCCCGCTCCGACCGACGCGGAAATCGCCAACCGCTACAAGCTCAACACCGCCGT
CTACGCGCCCAGCGAACAGCGCTCGGTCACGCAGGTGATCGTGCCGACCGAAGCCGCGGCGCGCGCGCTCGCCGCCGAAG
TCGGCAAGGGCGGCGCGCTCGACACGGCCGCCCGATCCAAGGGCCTCGTCGCCAGCAAGCTCGCCGACCAGACCCGCGAC
ACCCTTGCAAACCAGACGTCGAAGGCCGTAGCCGATGCCGCGTTCGCCGCCACGGCGGGCACGCTCGCCACGCCGGCGAA
GTCGGGCCTGGGCTGGCATGTGCTCAAGGTCGATGCGGTAAAGCGCAATCCCGGCAAGACGCTCGATCAGGCGCGCGCCG
AAATCGTCACGGCCCTGACGCTGGAAAAGCGCCGCGCGGCGCTTTCCGACCTCGCCGCGCAAGTCGAGCAGGAAATCGAC
AGCGGCACCGGCCTTGCCGACATCGCGAAGAACCTTGGCCTCACCGTCCAGACGACGCAGCCGCTGCTGGCCAACGGCAC
TGTCTTCGGCAAGGCGGCGGAAAAGGCGCCCGCCGATATCGCGCCGCTCGTCCAGGCCGCCTTTGCGATGGAACGGGAAG
GCGAAGCCCAGCTTGCCGAAATCAAGCCGGGCGAAAAGTTCGCCATCTACGACGTCGGACAACTCACCGCCGCGACCCCG
GCTCCACTTGCCGCCATCAAGGACGCCGTCGCCCGCGACTGGGCGCTCCAGCAGGGCTCGGCCAAGGCGAAGGCCGCCGC
CGACAGGATCCTCGCAGCGCTCGACAAGGGCACCCCGCTTGCCGAAGCCGTAAAGCTCGCCGGTGTCGCCATTCCCGCGC
CGCAGCCCATCGACATGGGCCGCCAGCAGATCGGCGCGATGCAGGGCCAGGTCCCGCCGCCGCTCGCGCTGCTCTTCGCC
ATGGCCGAAGGCAGCAACAAGCGCCTCGAGGGCCCGAACAAGGCCGGATGGTACGTCGTCTCGCTCAAGGACATCGTGCC
CGGCGCAGTGAAGCGCGAAGACCAGATCTTCGCCGGCGCCTCGCGCGAGCTGGGCGCCGTCACCGGCAACGAATATGCTG
AATCCCTGCGCCGCGCGATCGGCAAGGACCTTGGCATCGAACGCAACGAATCCGCGATCAAGGCCGTCCGCAACCAGCTG
ACCGGCGCGAACAACCAGTAA

Upstream 100 bases:

>100_bases
GCGACGCAGCCATTGCGGGAAACGCGTTTGCCTCCTAAGGCATCGCCCAATCCCAAACAGGGCGCCATCAGGCACCCAGA
CAAGAGACGAACACCCGCAA

Downstream 100 bases:

>100_bases
GTCCACAAAGACGATGACCACGATCGACGCATCCGCCGTCTCGCTGCCGGAAAACCACCGCGCCGCGCTTTCCCAGCTTT
CCGCCGGAAAGCCGGCGCTG

Product: hypothetical protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 646; Mature: 646

Protein sequence:

>646_residues
MLGFFRSFLKSRIGVAIALLFLGLIALAFASADVTGSGFGGVAGGDRAAKVGSGRIGTGELGKALTSAFEQDRQKQPGLT
MKQFLDGGGLEGVLSGMIDRLALAEWGKKHGLAVSDRLVDSEIVKIGAFQGPDGKFSQKAYEQLLAQRGLTDKEVRNDLA
QGLMARQLLLPAAFGAQMPAEAVLRYASLLTEKRVGTIISVPSLAFAPAGGPDDNALAAFYNANKGRYMQPERRTIRYAL
VDEATLKNVPAPTDAEIANRYKLNTAVYAPSEQRSVTQVIVPTEAAARALAAEVGKGGALDTAARSKGLVASKLADQTRD
TLANQTSKAVADAAFAATAGTLATPAKSGLGWHVLKVDAVKRNPGKTLDQARAEIVTALTLEKRRAALSDLAAQVEQEID
SGTGLADIAKNLGLTVQTTQPLLANGTVFGKAAEKAPADIAPLVQAAFAMEREGEAQLAEIKPGEKFAIYDVGQLTAATP
APLAAIKDAVARDWALQQGSAKAKAAADRILAALDKGTPLAEAVKLAGVAIPAPQPIDMGRQQIGAMQGQVPPPLALLFA
MAEGSNKRLEGPNKAGWYVVSLKDIVPGAVKREDQIFAGASRELGAVTGNEYAESLRRAIGKDLGIERNESAIKAVRNQL
TGANNQ

Sequences:

>Translated_646_residues
MLGFFRSFLKSRIGVAIALLFLGLIALAFASADVTGSGFGGVAGGDRAAKVGSGRIGTGELGKALTSAFEQDRQKQPGLT
MKQFLDGGGLEGVLSGMIDRLALAEWGKKHGLAVSDRLVDSEIVKIGAFQGPDGKFSQKAYEQLLAQRGLTDKEVRNDLA
QGLMARQLLLPAAFGAQMPAEAVLRYASLLTEKRVGTIISVPSLAFAPAGGPDDNALAAFYNANKGRYMQPERRTIRYAL
VDEATLKNVPAPTDAEIANRYKLNTAVYAPSEQRSVTQVIVPTEAAARALAAEVGKGGALDTAARSKGLVASKLADQTRD
TLANQTSKAVADAAFAATAGTLATPAKSGLGWHVLKVDAVKRNPGKTLDQARAEIVTALTLEKRRAALSDLAAQVEQEID
SGTGLADIAKNLGLTVQTTQPLLANGTVFGKAAEKAPADIAPLVQAAFAMEREGEAQLAEIKPGEKFAIYDVGQLTAATP
APLAAIKDAVARDWALQQGSAKAKAAADRILAALDKGTPLAEAVKLAGVAIPAPQPIDMGRQQIGAMQGQVPPPLALLFA
MAEGSNKRLEGPNKAGWYVVSLKDIVPGAVKREDQIFAGASRELGAVTGNEYAESLRRAIGKDLGIERNESAIKAVRNQL
TGANNQ
>Mature_646_residues
MLGFFRSFLKSRIGVAIALLFLGLIALAFASADVTGSGFGGVAGGDRAAKVGSGRIGTGELGKALTSAFEQDRQKQPGLT
MKQFLDGGGLEGVLSGMIDRLALAEWGKKHGLAVSDRLVDSEIVKIGAFQGPDGKFSQKAYEQLLAQRGLTDKEVRNDLA
QGLMARQLLLPAAFGAQMPAEAVLRYASLLTEKRVGTIISVPSLAFAPAGGPDDNALAAFYNANKGRYMQPERRTIRYAL
VDEATLKNVPAPTDAEIANRYKLNTAVYAPSEQRSVTQVIVPTEAAARALAAEVGKGGALDTAARSKGLVASKLADQTRD
TLANQTSKAVADAAFAATAGTLATPAKSGLGWHVLKVDAVKRNPGKTLDQARAEIVTALTLEKRRAALSDLAAQVEQEID
SGTGLADIAKNLGLTVQTTQPLLANGTVFGKAAEKAPADIAPLVQAAFAMEREGEAQLAEIKPGEKFAIYDVGQLTAATP
APLAAIKDAVARDWALQQGSAKAKAAADRILAALDKGTPLAEAVKLAGVAIPAPQPIDMGRQQIGAMQGQVPPPLALLFA
MAEGSNKRLEGPNKAGWYVVSLKDIVPGAVKREDQIFAGASRELGAVTGNEYAESLRRAIGKDLGIERNESAIKAVRNQL
TGANNQ

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=559, Percent_Identity=25.4025044722719, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 67468; Mature: 67468

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGFFRSFLKSRIGVAIALLFLGLIALAFASADVTGSGFGGVAGGDRAAKVGSGRIGTGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCHH
LGKALTSAFEQDRQKQPGLTMKQFLDGGGLEGVLSGMIDRLALAEWGKKHGLAVSDRLVD
HHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SEIVKIGAFQGPDGKFSQKAYEQLLAQRGLTDKEVRNDLAQGLMARQLLLPAAFGAQMPA
HHHHHEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
EAVLRYASLLTEKRVGTIISVPSLAFAPAGGPDDNALAAFYNANKGRYMQPERRTIRYAL
HHHHHHHHHHHHHHCCCEEECCCHHCCCCCCCCCCCEEEEEECCCCCCCCCHHHHEEHHH
VDEATLKNVPAPTDAEIANRYKLNTAVYAPSEQRSVTQVIVPTEAAARALAAEVGKGGAL
HCCHHHCCCCCCCCHHHHHHEEECEEEECCCCCCCCEEEEECCHHHHHHHHHHHCCCCCC
DTAARSKGLVASKLADQTRDTLANQTSKAVADAAFAATAGTLATPAKSGLGWHVLKVDAV
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEE
KRNPGKTLDQARAEIVTALTLEKRRAALSDLAAQVEQEIDSGTGLADIAKNLGLTVQTTQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCEEEEECC
PLLANGTVFGKAAEKAPADIAPLVQAAFAMEREGEAQLAEIKPGEKFAIYDVGQLTAATP
CHHHCCCEECCHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCCCC
APLAAIKDAVARDWALQQGSAKAKAAADRILAALDKGTPLAEAVKLAGVAIPAPQPIDMG
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCEECCCCCCHHHH
RQQIGAMQGQVPPPLALLFAMAEGSNKRLEGPNKAGWYVVSLKDIVPGAVKREDQIFAGA
HHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHCCCHHCCCCHHHCCC
SRELGAVTGNEYAESLRRAIGKDLGIERNESAIKAVRNQLTGANNQ
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLGFFRSFLKSRIGVAIALLFLGLIALAFASADVTGSGFGGVAGGDRAAKVGSGRIGTGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCHH
LGKALTSAFEQDRQKQPGLTMKQFLDGGGLEGVLSGMIDRLALAEWGKKHGLAVSDRLVD
HHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SEIVKIGAFQGPDGKFSQKAYEQLLAQRGLTDKEVRNDLAQGLMARQLLLPAAFGAQMPA
HHHHHEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
EAVLRYASLLTEKRVGTIISVPSLAFAPAGGPDDNALAAFYNANKGRYMQPERRTIRYAL
HHHHHHHHHHHHHHCCCEEECCCHHCCCCCCCCCCCEEEEEECCCCCCCCCHHHHEEHHH
VDEATLKNVPAPTDAEIANRYKLNTAVYAPSEQRSVTQVIVPTEAAARALAAEVGKGGAL
HCCHHHCCCCCCCCHHHHHHEEECEEEECCCCCCCCEEEEECCHHHHHHHHHHHCCCCCC
DTAARSKGLVASKLADQTRDTLANQTSKAVADAAFAATAGTLATPAKSGLGWHVLKVDAV
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEE
KRNPGKTLDQARAEIVTALTLEKRRAALSDLAAQVEQEIDSGTGLADIAKNLGLTVQTTQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCEEEEECC
PLLANGTVFGKAAEKAPADIAPLVQAAFAMEREGEAQLAEIKPGEKFAIYDVGQLTAATP
CHHHCCCEECCHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCCCC
APLAAIKDAVARDWALQQGSAKAKAAADRILAALDKGTPLAEAVKLAGVAIPAPQPIDMG
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCEECCCCCCHHHH
RQQIGAMQGQVPPPLALLFAMAEGSNKRLEGPNKAGWYVVSLKDIVPGAVKREDQIFAGA
HHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHCCCHHCCCCHHHCCC
SRELGAVTGNEYAESLRRAIGKDLGIERNESAIKAVRNQLTGANNQ
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]