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The map label for this gene is yafV [C]

Identifier: 87200028

GI number: 87200028

Start: 2145016

End: 2145861

Strand: Reverse

Name: yafV [C]

Synonym: Saro_2012

Alternate gene names: 87200028

Gene position: 2145861-2145016 (Counterclockwise)

Preceding gene: 87200029

Following gene: 87200027

Centisome position: 60.25

GC content: 67.26

Gene sequence:

>846_bases
GTGAGCAGCGGCGCACCGCGGGGACCTGCCAAGGTCGCGCTGTTCCAGATGACCAGCGGCATCGATCCGCTGGTCAATGC
CGCCGCCATCGTGGATGCCGCGACGCGCGCGGCCGAGGCCGGCGCGGCGATGCTGTTTACACCCGAGATGTGCGGCCTGC
TCGACCGCGAGCGCGCACGGGCAACGCGTCATATCGTTACCGAAGCCGAGAATCCGGTTCTGGCTTCGGCCCGAAAGGCG
GCGCGCGACCTTGGCATCTGGATAGACCTGGGTTCGCTGGCCATTCTGCGCGACGACGGCAAGTGGGCCAATCGCGGTTT
CGTGATCGATGCCGACGGGGCGGTCGCCGCGCGCTATGACAAGATACACATGTTCGACGTCGACCTTGCGACTGGCGAGA
CATGGCGGGAGTCGGCGGCGTACACGCCCGGCGAGCAGGTCGTGACGGTCGAGACGCCGGTCGGCATGCTTGGCATGGCG
ATCTGCTATGACGTGCGTTTTCCCGCGCTGTTCGAAGAGCTTGGCCGGCGCAGGTGCGACGCCATCCGCATTCCCGCCGC
ATTCACCGTGCCGACCGGCAAGGCGCATTGGCACCTGATGCAGCGCGCGCGCGCGGTCGAGGCAAGCGCGTGGGTGATCG
CGGCGGCCCAGGGCGGACGCCATGAGGACGGGCGCGAGACTTTCGGTCATTCGCTGGTGGTCGATCCGTGGGGCGAGGTG
GCGCTCGATGGTGGAGAGGGCACGTCGCTGGGCTATGCCGTGATCGATCCTGCCCGAACGGACGAGGTCAGGGCACAGCT
TCCCAGTCTTGCCAACAAGCGCGAAATCCCTAGATCGGCCCCATGA

Upstream 100 bases:

>100_bases
CCACCGTTCCCTCGATCTTCATCGACGGCCTCCACGTGGGCGGTTCCGATGACCTCGCCGCGCTCAACGCGCAGGGCAAG
CTGGACATGATGCTGGGCCT

Downstream 100 bases:

>100_bases
TTGTCTTTGATCTGCAATGCGGGCCGATGGGGCACCGTTTCGAGGGGTGGTTCGGCTCTTCGACGGATTTCGACGACCAA
TGCGCGCGCGGACTGGTGTC

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MSSGAPRGPAKVALFQMTSGIDPLVNAAAIVDAATRAAEAGAAMLFTPEMCGLLDRERARATRHIVTEAENPVLASARKA
ARDLGIWIDLGSLAILRDDGKWANRGFVIDADGAVAARYDKIHMFDVDLATGETWRESAAYTPGEQVVTVETPVGMLGMA
ICYDVRFPALFEELGRRRCDAIRIPAAFTVPTGKAHWHLMQRARAVEASAWVIAAAQGGRHEDGRETFGHSLVVDPWGEV
ALDGGEGTSLGYAVIDPARTDEVRAQLPSLANKREIPRSAP

Sequences:

>Translated_281_residues
MSSGAPRGPAKVALFQMTSGIDPLVNAAAIVDAATRAAEAGAAMLFTPEMCGLLDRERARATRHIVTEAENPVLASARKA
ARDLGIWIDLGSLAILRDDGKWANRGFVIDADGAVAARYDKIHMFDVDLATGETWRESAAYTPGEQVVTVETPVGMLGMA
ICYDVRFPALFEELGRRRCDAIRIPAAFTVPTGKAHWHLMQRARAVEASAWVIAAAQGGRHEDGRETFGHSLVVDPWGEV
ALDGGEGTSLGYAVIDPARTDEVRAQLPSLANKREIPRSAP
>Mature_280_residues
SSGAPRGPAKVALFQMTSGIDPLVNAAAIVDAATRAAEAGAAMLFTPEMCGLLDRERARATRHIVTEAENPVLASARKAA
RDLGIWIDLGSLAILRDDGKWANRGFVIDADGAVAARYDKIHMFDVDLATGETWRESAAYTPGEQVVTVETPVGMLGMAI
CYDVRFPALFEELGRRRCDAIRIPAAFTVPTGKAHWHLMQRARAVEASAWVIAAAQGGRHEDGRETFGHSLVVDPWGEVA
LDGGEGTSLGYAVIDPARTDEVRAQLPSLANKREIPRSAP

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI5031947, Length=268, Percent_Identity=36.1940298507463, Blast_Score=166, Evalue=1e-41,
Organism=Homo sapiens, GI297632348, Length=268, Percent_Identity=36.1940298507463, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI297632350, Length=268, Percent_Identity=36.1940298507463, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI9910460, Length=196, Percent_Identity=37.2448979591837, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI297632346, Length=191, Percent_Identity=32.9842931937173, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17556280, Length=270, Percent_Identity=37.4074074074074, Blast_Score=170, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6322335, Length=297, Percent_Identity=28.956228956229, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6323383, Length=174, Percent_Identity=35.632183908046, Blast_Score=140, Evalue=3e-34,
Organism=Drosophila melanogaster, GI17933642, Length=271, Percent_Identity=38.0073800738007, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI21355835, Length=264, Percent_Identity=26.5151515151515, Blast_Score=115, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30128; Mature: 29996

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSGAPRGPAKVALFQMTSGIDPLVNAAAIVDAATRAAEAGAAMLFTPEMCGLLDRERAR
CCCCCCCCCCEEEEEEHHCCCCHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHH
ATRHIVTEAENPVLASARKAARDLGIWIDLGSLAILRDDGKWANRGFVIDADGAVAARYD
HHHHHHHCCCCCHHHHHHHHHHHCEEEEEECCEEEEECCCCCCCCCEEEECCCCEEEEEC
KIHMFDVDLATGETWRESAAYTPGEQVVTVETPVGMLGMAICYDVRFPALFEELGRRRCD
EEEEEEEEECCCCHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHCCC
AIRIPAAFTVPTGKAHWHLMQRARAVEASAWVIAAAQGGRHEDGRETFGHSLVVDPWGEV
EEECCEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHCCEEEECCCCCE
ALDGGEGTSLGYAVIDPARTDEVRAQLPSLANKREIPRSAP
EEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SSGAPRGPAKVALFQMTSGIDPLVNAAAIVDAATRAAEAGAAMLFTPEMCGLLDRERAR
CCCCCCCCCEEEEEEHHCCCCHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHH
ATRHIVTEAENPVLASARKAARDLGIWIDLGSLAILRDDGKWANRGFVIDADGAVAARYD
HHHHHHHCCCCCHHHHHHHHHHHCEEEEEECCEEEEECCCCCCCCCEEEECCCCEEEEEC
KIHMFDVDLATGETWRESAAYTPGEQVVTVETPVGMLGMAICYDVRFPALFEELGRRRCD
EEEEEEEEECCCCHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHCCC
AIRIPAAFTVPTGKAHWHLMQRARAVEASAWVIAAAQGGRHEDGRETFGHSLVVDPWGEV
EEECCEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHCCEEEECCCCCE
ALDGGEGTSLGYAVIDPARTDEVRAQLPSLANKREIPRSAP
EEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]