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The map label for this gene is pgl [H]

Identifier: 87199911

GI number: 87199911

Start: 2006637

End: 2007263

Strand: Direct

Name: pgl [H]

Synonym: Saro_1894

Alternate gene names: 87199911

Gene position: 2006637-2007263 (Clockwise)

Preceding gene: 87199910

Following gene: 87199912

Centisome position: 56.34

GC content: 64.91

Gene sequence:

>627_bases
ATGACTGAGCCGCAACCGGCGACAGTCTCGTGGGCCCAGCCAGGCAATGCGACTGCGGTTGCCGATCATATCGCGCGGGT
CGTGAATGCACCGGGGCGGAAGAGGATCGCATTCACAGGCGGTTCGACGCCGATCAAGGTTCTGTCCCTGCTGAAGGATA
GACCGCTCGACTGGTCTTCGGTGACTATTGCGCTGACCGACGACCGGTGCGTGCCGGACGACCATCCGGCCAGCAATTTC
GGGAAGATCCACGCCGCGCTCGGCGCGTCCGGCGCACGGTTCGAGCGCCTTGAGGAAGGCGCACAGGTAGAGCCGTTCGA
CCTCGTCTGGCTCGGCATGGGAGAGGACGGACACGTCGCCTCGCTGTTTCCCCACATGCAGGCGGTGGTGCGTCCGGGAC
CGACGGTGATCGCGACGACGCCGATCCCGCTTCCGCCGGAAGCACCATTCGACAGGCTGACCCTGAACCGCAAGGCGCTC
AAGGCGAGCCGGGAGATAATCCTCGTGGTCACCGGCGCTTCCAAGAAGGCGCTGCTTGAGCGCGTCATTGCCGGCGACGA
TGGCTATCCCGTCGCCGATTTCCTGCGTGGCTATGGCCCGCCGGTCACGATCTACTGGAGCGAATGA

Upstream 100 bases:

>100_bases
GTCTGGGCCGACACCGACATGGAAGCCAAGCCCTATGCCGCAGGAAGCTGGGGGCCGAACGCAGGCATCGCCCTTACCGA
GCGGGACGGGAGAAGCTGGA

Downstream 100 bases:

>100_bases
TGGCGATGAACCCAACTGTCGAGCGCGTCACCCAGCGCATCATCGAGCGTTCGCGCAGCACCCGCGCCGCATATCTCGAT
CTTGTGGAACGTTCGCGCGA

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MTEPQPATVSWAQPGNATAVADHIARVVNAPGRKRIAFTGGSTPIKVLSLLKDRPLDWSSVTIALTDDRCVPDDHPASNF
GKIHAALGASGARFERLEEGAQVEPFDLVWLGMGEDGHVASLFPHMQAVVRPGPTVIATTPIPLPPEAPFDRLTLNRKAL
KASREIILVVTGASKKALLERVIAGDDGYPVADFLRGYGPPVTIYWSE

Sequences:

>Translated_208_residues
MTEPQPATVSWAQPGNATAVADHIARVVNAPGRKRIAFTGGSTPIKVLSLLKDRPLDWSSVTIALTDDRCVPDDHPASNF
GKIHAALGASGARFERLEEGAQVEPFDLVWLGMGEDGHVASLFPHMQAVVRPGPTVIATTPIPLPPEAPFDRLTLNRKAL
KASREIILVVTGASKKALLERVIAGDDGYPVADFLRGYGPPVTIYWSE
>Mature_207_residues
TEPQPATVSWAQPGNATAVADHIARVVNAPGRKRIAFTGGSTPIKVLSLLKDRPLDWSSVTIALTDDRCVPDDHPASNFG
KIHAALGASGARFERLEEGAQVEPFDLVWLGMGEDGHVASLFPHMQAVVRPGPTVIATTPIPLPPEAPFDRLTLNRKALK
ASREIILVVTGASKKALLERVIAGDDGYPVADFLRGYGPPVTIYWSE

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=213, Percent_Identity=29.5774647887324, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24641119, Length=179, Percent_Identity=28.4916201117318, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 22305; Mature: 22174

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPQPATVSWAQPGNATAVADHIARVVNAPGRKRIAFTGGSTPIKVLSLLKDRPLDWSS
CCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCE
VTIALTDDRCVPDDHPASNFGKIHAALGASGARFERLEEGAQVEPFDLVWLGMGEDGHVA
EEEEEECCCCCCCCCCCCCCCEEEHHHCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCHH
SLFPHMQAVVRPGPTVIATTPIPLPPEAPFDRLTLNRKALKASREIILVVTGASKKALLE
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHCCCHHHHHCCCEEEEEEECCCHHHHHH
RVIAGDDGYPVADFLRGYGPPVTIYWSE
HHHCCCCCCCHHHHHHCCCCCEEEEECC
>Mature Secondary Structure 
TEPQPATVSWAQPGNATAVADHIARVVNAPGRKRIAFTGGSTPIKVLSLLKDRPLDWSS
CCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCE
VTIALTDDRCVPDDHPASNFGKIHAALGASGARFERLEEGAQVEPFDLVWLGMGEDGHVA
EEEEEECCCCCCCCCCCCCCCEEEHHHCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCHH
SLFPHMQAVVRPGPTVIATTPIPLPPEAPFDRLTLNRKALKASREIILVVTGASKKALLE
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHCCCHHHHHCCCEEEEEEECCCHHHHHH
RVIAGDDGYPVADFLRGYGPPVTIYWSE
HHHCCCCCCCHHHHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]