BacMap

Definition	Novosphingobium aromaticivorans DSM 12444 chromosome, complete genome.
Accession	NC_007794
Length	3,561,584

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The map label for this gene is ligD [H]

Identifier: 87199892

GI number: 87199892

Start: 1976401

End: 1977243

Strand: Direct

Name: ligD [H]

Synonym: Saro_1875

Alternate gene names: 87199892

Gene position: 1976401-1977243 (Clockwise)

Preceding gene: 87199891

Following gene: 87199894

Centisome position: 55.49

GC content: 64.65

Gene sequence:

>843_bases
ATGGGCATTGAAACCTTCGCGGGACGAACCGCATTCGTCACCGGTGGAGCATCCGGAATAGGCCTGGGCATCGTCAAGGC
GCTCGCCCGGCGGGACGCCTTCGTGGTGATCGCGGACATGCGCACCGATCACATCTCGAGGGCATTGAAGGCGCTGGCAT
CAGCAGGTCTGGGCGAGAGCGTTGCCGCAGTGGAACTCGATGTGACGGACCGGGCCGCATATGCGAGCATGGCGCGCCGC
ATGGATGAAGAGTTCGGCGGGATAGACGTTCTGGTCAACAATGCCGGCGTGGGTGTCGAAGGGCCCATTCTGCAGGCGAC
CTACCCCGACTGGGACTTCGGGCTTGGCGTCAACCTGGGCGGCGTGGTCAACGGGCTTCAGGCAATGCTGCCGCAGATGA
TCGCGCATGGGCGCGGCGGCCATGTCGTCAACACCGCATCGCTGGCTGCCACGGTCGTCATGCCCGGTCATCTTGCGATC
TATGCCGCAGGCAAGGCGGCGGTGCTGAACCTGACCGAGAACATGCGTGCCGATCTTGCCGGGCGCGGGATAGGCAGCAG
CGTGCTGTGCCCCGGTTTCGTCCGGTCTAACATCCATGAAGCCGCGCGCAACCGGCCGGCCCACCTGCGCGAGGGAAGTG
GCTTTGCGGCTTCCGAGCAGGCGTTGTCGATGCGGGAGACGGGCAGCGAGTGGATGGATCCGGATGCCGTGGGCGAAATG
GTGGCGGACGCCATTCTCGCCGATCAACTCTATGTCATCACTCACGGTGAATTCGCAAACCGGATGCGCGAGCGCGCCGA
AGCGCTGCTTGCGGCCACCCCGGTCTGCGAGATGCAGTTCTGA

Upstream 100 bases:

>100_bases
GCCGGACGTGTTCGAGAGCCTGCGCAAGCGCACGCATCAGTGCAAGGTGCTGATAAATCCGGGCGAATGATCGATCCCCG
GCAAGCTGGAGCAGGGGCCC

Downstream 100 bases:

>100_bases
CCGGTCAGGTTGAAATGCCGATGGTGGTCGTTGCGGTGTAGCCGCCGGATACCGACCCGGTCATCGTCGGCGTCATTACC
GCGAGCTGCGCGCTTGTCGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MGIETFAGRTAFVTGGASGIGLGIVKALARRDAFVVIADMRTDHISRALKALASAGLGESVAAVELDVTDRAAYASMARR
MDEEFGGIDVLVNNAGVGVEGPILQATYPDWDFGLGVNLGGVVNGLQAMLPQMIAHGRGGHVVNTASLAATVVMPGHLAI
YAAGKAAVLNLTENMRADLAGRGIGSSVLCPGFVRSNIHEAARNRPAHLREGSGFAASEQALSMRETGSEWMDPDAVGEM
VADAILADQLYVITHGEFANRMRERAEALLAATPVCEMQF

Sequences:

>Translated_280_residues
MGIETFAGRTAFVTGGASGIGLGIVKALARRDAFVVIADMRTDHISRALKALASAGLGESVAAVELDVTDRAAYASMARR
MDEEFGGIDVLVNNAGVGVEGPILQATYPDWDFGLGVNLGGVVNGLQAMLPQMIAHGRGGHVVNTASLAATVVMPGHLAI
YAAGKAAVLNLTENMRADLAGRGIGSSVLCPGFVRSNIHEAARNRPAHLREGSGFAASEQALSMRETGSEWMDPDAVGEM
VADAILADQLYVITHGEFANRMRERAEALLAATPVCEMQF
>Mature_279_residues
GIETFAGRTAFVTGGASGIGLGIVKALARRDAFVVIADMRTDHISRALKALASAGLGESVAAVELDVTDRAAYASMARRM
DEEFGGIDVLVNNAGVGVEGPILQATYPDWDFGLGVNLGGVVNGLQAMLPQMIAHGRGGHVVNTASLAATVVMPGHLAIY
AAGKAAVLNLTENMRADLAGRGIGSSVLCPGFVRSNIHEAARNRPAHLREGSGFAASEQALSMRETGSEWMDPDAVGEMV
ADAILADQLYVITHGEFANRMRERAEALLAATPVCEMQF

Specific function: Catalyzes the C alpha dehydrogenation of arylglycerol- beta-aryl ether (C alpha alcohol type) (compound IV) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI31542939, Length=199, Percent_Identity=31.1557788944724, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI32483357, Length=197, Percent_Identity=31.4720812182741, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI33667109, Length=201, Percent_Identity=33.8308457711443, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI5031737, Length=196, Percent_Identity=33.1632653061224, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI66933014, Length=205, Percent_Identity=29.7560975609756, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI7706318, Length=196, Percent_Identity=30.1020408163265, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI142976729, Length=196, Percent_Identity=28.0612244897959, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI20149619, Length=187, Percent_Identity=32.0855614973262, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI126723191, Length=207, Percent_Identity=29.4685990338164, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI224922801, Length=168, Percent_Identity=30.952380952381, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI40807363, Length=250, Percent_Identity=24.4, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI109715829, Length=204, Percent_Identity=26.4705882352941, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7657478, Length=192, Percent_Identity=32.2916666666667, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI210032110, Length=206, Percent_Identity=26.6990291262136, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI19923817, Length=198, Percent_Identity=28.2828282828283, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI7705925, Length=201, Percent_Identity=30.3482587064677, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI223718074, Length=275, Percent_Identity=30.1818181818182, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=239, Percent_Identity=35.9832635983264, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787335, Length=197, Percent_Identity=31.4720812182741, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790717, Length=235, Percent_Identity=28.5106382978723, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787820, Length=185, Percent_Identity=32.4324324324324, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789208, Length=203, Percent_Identity=28.0788177339901, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082160, Length=211, Percent_Identity=27.9620853080569, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1786812, Length=194, Percent_Identity=30.4123711340206, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786701, Length=248, Percent_Identity=27.4193548387097, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI2367175, Length=192, Percent_Identity=27.0833333333333, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788459, Length=186, Percent_Identity=27.9569892473118, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=196, Percent_Identity=30.1020408163265, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=200, Percent_Identity=30, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=198, Percent_Identity=29.7979797979798, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=195, Percent_Identity=28.7179487179487, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=196, Percent_Identity=29.0816326530612, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=202, Percent_Identity=28.2178217821782, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=257, Percent_Identity=23.7354085603113, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=201, Percent_Identity=28.3582089552239, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=233, Percent_Identity=30.4721030042918, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=233, Percent_Identity=30.4721030042918, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=202, Percent_Identity=28.2178217821782, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=207, Percent_Identity=26.0869565217391, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=196, Percent_Identity=28.0612244897959, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=211, Percent_Identity=25.5924170616114, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=204, Percent_Identity=28.921568627451, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=25.2525252525253, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=219, Percent_Identity=27.3972602739726, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=192, Percent_Identity=27.0833333333333, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=207, Percent_Identity=27.0531400966184, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=248, Percent_Identity=22.5806451612903, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=23.9837398373984, Blast_Score=64, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=203, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=198, Percent_Identity=28.2828282828283, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21358495, Length=270, Percent_Identity=25.1851851851852, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24665243, Length=197, Percent_Identity=33.502538071066, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221331218, Length=197, Percent_Identity=33.502538071066, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI23397609, Length=195, Percent_Identity=32.3076923076923, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24665247, Length=198, Percent_Identity=33.8383838383838, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221331216, Length=198, Percent_Identity=33.8383838383838, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355631, Length=176, Percent_Identity=32.9545454545455, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24639444, Length=196, Percent_Identity=32.1428571428571, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24581726, Length=213, Percent_Identity=28.6384976525822, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24643142, Length=202, Percent_Identity=31.6831683168317, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571526, Length=198, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI281364892, Length=173, Percent_Identity=31.2138728323699, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24644339, Length=197, Percent_Identity=28.4263959390863, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355319, Length=200, Percent_Identity=27.5, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17647419, Length=259, Percent_Identity=22.007722007722, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21357041, Length=195, Percent_Identity=27.1794871794872, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161076933, Length=196, Percent_Identity=29.5918367346939, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584748, Length=196, Percent_Identity=29.5918367346939, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17737361, Length=234, Percent_Identity=28.6324786324786, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29248; Mature: 29117

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIETFAGRTAFVTGGASGIGLGIVKALARRDAFVVIADMRTDHISRALKALASAGLGES
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCC
VAAVELDVTDRAAYASMARRMDEEFGGIDVLVNNAGVGVEGPILQATYPDWDFGLGVNLG
EEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCHH
GVVNGLQAMLPQMIAHGRGGHVVNTASLAATVVMPGHLAIYAAGKAAVLNLTENMRADLA
HHHHHHHHHHHHHHHCCCCCCEEEHHHHHEEEEECCCEEEEECCCEEEEECHHHHHHHHC
GRGIGSSVLCPGFVRSNIHEAARNRPAHLREGSGFAASEQALSMRETGSEWMDPDAVGEM
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
VADAILADQLYVITHGEFANRMRERAEALLAATPVCEMQF
HHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GIETFAGRTAFVTGGASGIGLGIVKALARRDAFVVIADMRTDHISRALKALASAGLGES
CCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCC
VAAVELDVTDRAAYASMARRMDEEFGGIDVLVNNAGVGVEGPILQATYPDWDFGLGVNLG
EEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCHH
GVVNGLQAMLPQMIAHGRGGHVVNTASLAATVVMPGHLAIYAAGKAAVLNLTENMRADLA
HHHHHHHHHHHHHHHCCCCCCEEEHHHHHEEEEECCCEEEEECCCEEEEECHHHHHHHHC
GRGIGSSVLCPGFVRSNIHEAARNRPAHLREGSGFAASEQALSMRETGSEWMDPDAVGEM
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
VADAILADQLYVITHGEFANRMRERAEALLAATPVCEMQF
HHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1744051; 8495726; 7764263 [H]