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The map label for this gene is ldc [H]

Identifier: 87199811

GI number: 87199811

Start: 1891915

End: 1893120

Strand: Direct

Name: ldc [H]

Synonym: Saro_1794

Alternate gene names: 87199811

Gene position: 1891915-1893120 (Clockwise)

Preceding gene: 87199810

Following gene: 87199817

Centisome position: 53.12

GC content: 63.52

Gene sequence:

>1206_bases
TTGCACATCCATCCTGACGCACTGGCTGTAGTTCGCGCCTCGGCGCCGGACCAACCCGCCATTCTCAATCGCCCGCACGC
CGCTGCGCGCGCTGCCCGCTTCTTTGTGGAGAAGTTTCCGGGCAAGTCGCTCTATGCGGTGAAGGCCAATCCTTCGGCCG
ATCTGCTGCGCGTCCTTTGGGATTCGGGCGTGACTCACTACGATGTTGCGTCGATCGCGGAAGTGCGCCTCGTGCGCGCG
ACGCTGCCGGAAGCGACGCTTTGCTTCATGCACCCGGTAAAGGCGCCCGCCGCCATCCGCGAAGCCTACGAACAGCACGG
CGTGCGCGTGTTCAGCCTCGATTCCTTCGAGGAACTGGAAAAGATCAAGGAAGCCTGCGGCTTTGCCGAGGACCTGACGC
TTTGCGTGCGCCTGCGCGTCTCTTCCGATTATTCGGAACTCAGCCTTGCATCCAAGTTCGGTTGCGATCTGACCAATGCC
GCGGAACTGCTCCAGGCAACGCGTCAGGCTGCGGATTCTCTCGGCGTCTGCTTCCACGTCGGCAGCCAGTCGATGAGCCC
GCATGCCTATGTCCAGGCGCTGGAGCGCGTGCGCGCGGCCATCGTCGACGCGTCGGTCACGGTCGACATCATCGATGTTG
GCGGCGGCTTTCCGTCGATCTATCCGGGCATGGAACCGCCCCCGCTCGAAGATTACTTCGGCGTGATCGACCGCACCTAT
GAATCGTTGCCGATTTCCTACTCGGCGGAACTGTGGTGCGAACCGGGCCGTGCGCTCTGCGCCGAATACAACTCGATGAT
CGTGCGGGTCGAGCGCCGTCGCGGCGCGGAGCTCTACATCAACGACGGCGCCTATGGCGCGCTGTTCGATGCCGCCCACG
TCGGTTGGCGCTTCCCCGTTCGCGTCCTGCGCGAAGAGGTGGCGAACGACGGCGTGGAAATCGAGATGGAGCCCTTCAGC
TTCTACGGCCCGACCTGCGACGACATGGACCACATGGAAGGTCCGTTCGAGCTTCCGGCCGACATGAAGGTGGGCGACTA
CATCGAGATCGGCATGCTTGGCGCTTATGGCGCGGCTATGAAGACCGCGTTCAACGGCTTCGGCGCAACCGAGGTCTTCG
AAGTCTCCGACGAACCGATGGCGAGCCAGTATCGCGGCGACCGTCGCGACCCTCGCGTGTCGGACAACGTCGTCTCGCTG
CGCTGA

Upstream 100 bases:

>100_bases
TTCATCGCAACGGCCTTATTTACCCCCCTCTCGCTGCCCCATGGGGACTTCCAAACCGCAAGGCAGCCTTGTTCAACGTT
CCGTTTGGGGGTCCCTTGAG

Downstream 100 bases:

>100_bases
ACCGCGCAAGCCTGAATGAGACAAGGAAAGGCCCTGCCGAAAGGCGGGGCCTTTTCGTTGCAGGGTGCGGCGTTACCCGG
GCATGCGTCCCCACAGCCAC

Product: Orn/DAP/Arg decarboxylase 2

Products: NA

Alternate protein names: LDC [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MHIHPDALAVVRASAPDQPAILNRPHAAARAARFFVEKFPGKSLYAVKANPSADLLRVLWDSGVTHYDVASIAEVRLVRA
TLPEATLCFMHPVKAPAAIREAYEQHGVRVFSLDSFEELEKIKEACGFAEDLTLCVRLRVSSDYSELSLASKFGCDLTNA
AELLQATRQAADSLGVCFHVGSQSMSPHAYVQALERVRAAIVDASVTVDIIDVGGGFPSIYPGMEPPPLEDYFGVIDRTY
ESLPISYSAELWCEPGRALCAEYNSMIVRVERRRGAELYINDGAYGALFDAAHVGWRFPVRVLREEVANDGVEIEMEPFS
FYGPTCDDMDHMEGPFELPADMKVGDYIEIGMLGAYGAAMKTAFNGFGATEVFEVSDEPMASQYRGDRRDPRVSDNVVSL
R

Sequences:

>Translated_401_residues
MHIHPDALAVVRASAPDQPAILNRPHAAARAARFFVEKFPGKSLYAVKANPSADLLRVLWDSGVTHYDVASIAEVRLVRA
TLPEATLCFMHPVKAPAAIREAYEQHGVRVFSLDSFEELEKIKEACGFAEDLTLCVRLRVSSDYSELSLASKFGCDLTNA
AELLQATRQAADSLGVCFHVGSQSMSPHAYVQALERVRAAIVDASVTVDIIDVGGGFPSIYPGMEPPPLEDYFGVIDRTY
ESLPISYSAELWCEPGRALCAEYNSMIVRVERRRGAELYINDGAYGALFDAAHVGWRFPVRVLREEVANDGVEIEMEPFS
FYGPTCDDMDHMEGPFELPADMKVGDYIEIGMLGAYGAAMKTAFNGFGATEVFEVSDEPMASQYRGDRRDPRVSDNVVSL
R
>Mature_401_residues
MHIHPDALAVVRASAPDQPAILNRPHAAARAARFFVEKFPGKSLYAVKANPSADLLRVLWDSGVTHYDVASIAEVRLVRA
TLPEATLCFMHPVKAPAAIREAYEQHGVRVFSLDSFEELEKIKEACGFAEDLTLCVRLRVSSDYSELSLASKFGCDLTNA
AELLQATRQAADSLGVCFHVGSQSMSPHAYVQALERVRAAIVDASVTVDIIDVGGGFPSIYPGMEPPPLEDYFGVIDRTY
ESLPISYSAELWCEPGRALCAEYNSMIVRVERRRGAELYINDGAYGALFDAAHVGWRFPVRVLREEVANDGVEIEMEPFS
FYGPTCDDMDHMEGPFELPADMKVGDYIEIGMLGAYGAAMKTAFNGFGATEVFEVSDEPMASQYRGDRRDPRVSDNVVSL
R

Specific function: Decarboxylates both L-lysine and L-ornithine with similar catalytic efficiency [H]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

Organism=Homo sapiens, GI4505489, Length=388, Percent_Identity=29.1237113402062, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI16506287, Length=373, Percent_Identity=26.5415549597855, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI22538418, Length=359, Percent_Identity=25.0696378830084, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI21361583, Length=359, Percent_Identity=25.0696378830084, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562780, Length=370, Percent_Identity=29.4594594594595, Blast_Score=108, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6322664, Length=366, Percent_Identity=28.1420765027322, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24586472, Length=369, Percent_Identity=25.7452574525745, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24586474, Length=345, Percent_Identity=27.2463768115942, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183
- InterPro:   IPR002433 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.17; =4.1.1.18 [H]

Molecular weight: Translated: 44106; Mature: 44106

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00878 ODR_DC_2_1 ; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIHPDALAVVRASAPDQPAILNRPHAAARAARFFVEKFPGKSLYAVKANPSADLLRVLW
CCCCCCHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHH
DSGVTHYDVASIAEVRLVRATLPEATLCFMHPVKAPAAIREAYEQHGVRVFSLDSFEELE
HCCCCHHHHHHHHHHHHHHHHCCCHHEEECCCCCCHHHHHHHHHHCCCEEEECCCHHHHH
KIKEACGFAEDLTLCVRLRVSSDYSELSLASKFGCDLTNAAELLQATRQAADSLGVCFHV
HHHHHCCCHHHEEEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEE
GSQSMSPHAYVQALERVRAAIVDASVTVDIIDVGGGFPSIYPGMEPPPLEDYFGVIDRTY
CCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
ESLPISYSAELWCEPGRALCAEYNSMIVRVERRRGAELYINDGAYGALFDAAHVGWRFPV
HHCCCCCCHHEEECCCHHHHHHHHHHEEEEECCCCCEEEECCCCCCHHHHHHHCCCCCHH
RVLREEVANDGVEIEMEPFSFYGPTCDDMDHMEGPFELPADMKVGDYIEIGMLGAYGAAM
HHHHHHHHCCCCEEEECCCEECCCCCCCHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHH
KTAFNGFGATEVFEVSDEPMASQYRGDRRDPRVSDNVVSLR
HHHHCCCCCCEEEECCCCCHHHHHCCCCCCCCCCCCCEECC
>Mature Secondary Structure
MHIHPDALAVVRASAPDQPAILNRPHAAARAARFFVEKFPGKSLYAVKANPSADLLRVLW
CCCCCCHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHH
DSGVTHYDVASIAEVRLVRATLPEATLCFMHPVKAPAAIREAYEQHGVRVFSLDSFEELE
HCCCCHHHHHHHHHHHHHHHHCCCHHEEECCCCCCHHHHHHHHHHCCCEEEECCCHHHHH
KIKEACGFAEDLTLCVRLRVSSDYSELSLASKFGCDLTNAAELLQATRQAADSLGVCFHV
HHHHHCCCHHHEEEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEE
GSQSMSPHAYVQALERVRAAIVDASVTVDIIDVGGGFPSIYPGMEPPPLEDYFGVIDRTY
CCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
ESLPISYSAELWCEPGRALCAEYNSMIVRVERRRGAELYINDGAYGALFDAAHVGWRFPV
HHCCCCCCHHEEECCCHHHHHHHHHHEEEEECCCCCEEEECCCCCCHHHHHHHCCCCCHH
RVLREEVANDGVEIEMEPFSFYGPTCDDMDHMEGPFELPADMKVGDYIEIGMLGAYGAAM
HHHHHHHHCCCCEEEECCCEECCCCCCCHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHH
KTAFNGFGATEVFEVSDEPMASQYRGDRRDPRVSDNVVSLR
HHHHCCCCCCEEEECCCCCHHHHHCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11073919 [H]