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The map label for this gene is czcR [H]

Identifier: 87199682

GI number: 87199682

Start: 1745307

End: 1746230

Strand: Direct

Name: czcR [H]

Synonym: Saro_1665

Alternate gene names: 87199682

Gene position: 1745307-1746230 (Clockwise)

Preceding gene: 87199681

Following gene: 87199684

Centisome position: 49.0

GC content: 64.72

Gene sequence:

>924_bases
ATGACGACTGGCGAATACGAGCGGCGGGACACCGTGCTGGTGGTGGACGACGAGCCGGATTCGCTGCGTTTCCTTGCGGA
TACGCTGGAGGGCGCGGGTATCCGGGTGCTTGTCGCGATTTCGGGCGATGCGGCTCTCGACGTGCTGCAGCATGTGGAGC
CGGACCTGATCCTGATGGATGGGGTAATGCCGGGGAGAAGCGGCTTCGAGACGACGGCGTGCATCAAGGCGCGCCCCGAA
CTTGCCCATGTGCCGGTCGTCTTCATGACAGGGCTGCACGACGACGAACACGTCGTCCGCGGTTTCGAGGTGGGCGGGGT
CGACTATCTGCGCAAGCCTGTGAATGTCCAGGAACTGCTTGCGCGGGTTCGGGTTCACGTTGGCAATGCCCGCGCAATCC
AGGCGGGTGCCGCAGGCCTCGACGCGACTGGTCGGCTGATGATGGCGACGGACCTGCAAGGTGGCTTGCTATGGTGCACA
CCCTTGGCCGAACGGGCGATAGCGCGGGCATGTCCGGGCTGGAGCCGCGACGCAGGCGCGCTACCGGATGCCCTTCGCGA
ACCGGTCCGCAAGATGCTGGGGCGCGGTGCGGCGCAGTCTGGGTCAGTCAAGGTCGAGCAGGTCGACGGCACGATGGAAC
TGGTCGTGATCGCGCAGTATCGCGGGCAGGAAGTCCTGATCCGAGTGAACGAGCTGAACCCGAAAGCCGACATCGCCCTG
CTGCAGCAGAAGCTGGGCCTTACCGACCGGGAGGCCGAAGTGCTGCTGTGGACCAGCTATGGCAAGTCCAATGCGACGAT
ATCGGAAGTCCTCGCCATCAGCCCCCGCACGGTCCAGAAACATCTGGAACGCATCTACGAAAAGCTGGGGATCGAAACCC
GCGCAGCCGCAGCGGCGGTCGCGATCAAGGCGCTGGGCAACTAG

Upstream 100 bases:

>100_bases
TGCAGGAAACGGACACCGGGACGGCGCCACTTGCCGCGCGCCTCTTCGATTGCCTCGACCGGTGCGACCTCGTGGCGATG
CGGCGGGTGTTGGAGGGCAT

Downstream 100 bases:

>100_bases
GCCACGAGGGCAGCGCCACCTGCGGCAGGAGGCGCTGCCCTGACAGGTTTCAGCGGCTGTGCGCCGGTGCGGCGCGGTGC
GCGGCCTGGGCCATGCGCTT

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MTTGEYERRDTVLVVDDEPDSLRFLADTLEGAGIRVLVAISGDAALDVLQHVEPDLILMDGVMPGRSGFETTACIKARPE
LAHVPVVFMTGLHDDEHVVRGFEVGGVDYLRKPVNVQELLARVRVHVGNARAIQAGAAGLDATGRLMMATDLQGGLLWCT
PLAERAIARACPGWSRDAGALPDALREPVRKMLGRGAAQSGSVKVEQVDGTMELVVIAQYRGQEVLIRVNELNPKADIAL
LQQKLGLTDREAEVLLWTSYGKSNATISEVLAISPRTVQKHLERIYEKLGIETRAAAAAVAIKALGN

Sequences:

>Translated_307_residues
MTTGEYERRDTVLVVDDEPDSLRFLADTLEGAGIRVLVAISGDAALDVLQHVEPDLILMDGVMPGRSGFETTACIKARPE
LAHVPVVFMTGLHDDEHVVRGFEVGGVDYLRKPVNVQELLARVRVHVGNARAIQAGAAGLDATGRLMMATDLQGGLLWCT
PLAERAIARACPGWSRDAGALPDALREPVRKMLGRGAAQSGSVKVEQVDGTMELVVIAQYRGQEVLIRVNELNPKADIAL
LQQKLGLTDREAEVLLWTSYGKSNATISEVLAISPRTVQKHLERIYEKLGIETRAAAAAVAIKALGN
>Mature_306_residues
TTGEYERRDTVLVVDDEPDSLRFLADTLEGAGIRVLVAISGDAALDVLQHVEPDLILMDGVMPGRSGFETTACIKARPEL
AHVPVVFMTGLHDDEHVVRGFEVGGVDYLRKPVNVQELLARVRVHVGNARAIQAGAAGLDATGRLMMATDLQGGLLWCTP
LAERAIARACPGWSRDAGALPDALREPVRKMLGRGAAQSGSVKVEQVDGTMELVVIAQYRGQEVLIRVNELNPKADIALL
QQKLGLTDREAEVLLWTSYGKSNATISEVLAISPRTVQKHLERIYEKLGIETRAAAAAVAIKALGN

Specific function: Member of the two-component regulatory system CzcS/CzcR involved in the control of cobalt, zinc and cadmium homeostasis [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=144, Percent_Identity=32.6388888888889, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788394, Length=113, Percent_Identity=33.6283185840708, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=34.4827586206897, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1790863, Length=200, Percent_Identity=27, Blast_Score=61, Evalue=9e-11,
Organism=Escherichia coli, GI1786784, Length=113, Percent_Identity=33.6283185840708, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 33098; Mature: 32966

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2 ; PS00867 CPSASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGEYERRDTVLVVDDEPDSLRFLADTLEGAGIRVLVAISGDAALDVLQHVEPDLILMD
CCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCEEEEE
GVMPGRSGFETTACIKARPELAHVPVVFMTGLHDDEHVVRGFEVGGVDYLRKPVNVQELL
CCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCHHHHCEEEECCHHHHHCCCCHHHHH
ARVRVHVGNARAIQAGAAGLDATGRLMMATDLQGGLLWCTPLAERAIARACPGWSRDAGA
HHHHHCCCCCEEEECCCCCCCCCCCEEEEEECCCCEEEECHHHHHHHHHHCCCCCCCCCC
LPDALREPVRKMLGRGAAQSGSVKVEQVDGTMELVVIAQYRGQEVLIRVNELNPKADIAL
CCHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEEEEECCCCEEEEEEECCCCHHHHHH
LQQKLGLTDREAEVLLWTSYGKSNATISEVLAISPRTVQKHLERIYEKLGIETRAAAAAV
HHHHHCCCCCCCCEEEEECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
AIKALGN
HHHCCCC
>Mature Secondary Structure 
TTGEYERRDTVLVVDDEPDSLRFLADTLEGAGIRVLVAISGDAALDVLQHVEPDLILMD
CCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCEEEEE
GVMPGRSGFETTACIKARPELAHVPVVFMTGLHDDEHVVRGFEVGGVDYLRKPVNVQELL
CCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCHHHHCEEEECCHHHHHCCCCHHHHH
ARVRVHVGNARAIQAGAAGLDATGRLMMATDLQGGLLWCTPLAERAIARACPGWSRDAGA
HHHHHCCCCCEEEECCCCCCCCCCCEEEEEECCCCEEEECHHHHHHHHHHCCCCCCCCCC
LPDALREPVRKMLGRGAAQSGSVKVEQVDGTMELVVIAQYRGQEVLIRVNELNPKADIAL
CCHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEEEEECCCCEEEEEEECCCCHHHHHH
LQQKLGLTDREAEVLLWTSYGKSNATISEVLAISPRTVQKHLERIYEKLGIETRAAAAAV
HHHHHCCCCCCCCEEEEECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
AIKALGN
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9044283 [H]