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The map label for this gene is arcB [H]

Identifier: 87199681

GI number: 87199681

Start: 1743718

End: 1745310

Strand: Direct

Name: arcB [H]

Synonym: Saro_1664

Alternate gene names: 87199681

Gene position: 1743718-1745310 (Clockwise)

Preceding gene: 87199680

Following gene: 87199682

Centisome position: 48.96

GC content: 66.54

Gene sequence:

>1593_bases
ATGATCGCGCTGCCGCGCTTCGCCGCCCTGCCATCGCGTGGCGTTCCCATCGCCGCGGCATGGGCGGCGCTGGCGGTGGC
CCTTCTGATCGTGGACGCCGTGGTGCCCGGAGAGAGCCTTGCGCTTCACGGCGCTACTCTCACCAGCTTCTGCATCTTCG
TTCTCACCTGCATTCGCCAGGCGCGGCGGGACGACGACAGCCAAGACACGGACCGCGAAGCCCTGCGCCAGGAGCTTGAC
GCTGCCGAATGCGCCAGCGCTGCGAAGAGCCGGTATCTTGCCAGCGTCAGCCACGAGATCCGCTCGCCGCTCAATGCGAT
CTATGGCTATGCGCAGCTCGTCGAGCGCGAAGGCACGGTCGATCCGCGCGATGCGGCCAGGGTCATCCGTCGCAGCGCCG
AACATCTCACTAACCTCGTGGAAGGCCTGCTCGACATCGCCTCGATCGAACAGGGCGTAGTGCGCATCGACAGCACGGTT
GCACGCCTCGATGCGCTGGTCGAGCAGGTGGCGGAAATGTTCCGGCCGCTCGCGGTGCAGAAGGGCCTCGCGTTCCGCTG
CGATCTTCCCGCGCGTCTGCCCGAGTTCGTGCGGATGGACGAACGTCGGGTGCGGCAGGTGTTGATCAACCTTGTCTCCA
ACGCGGTGAAGTTCACCCAGGCGGGCGAAGTGGTCCTGGCGGTGCGCTGGAGCGGCGAAATAGCGACATTCGAAGTGCGC
GATACCGGCCCGGGCATTTCCCCGGCCCATCAGGAGACGGTATTCTCGCCCTACCAGACTGGTGGGGTCGAATGTGGCGG
CGGTGCCGGACTGGGACTGGCGATCACGCGTGCGATAGTCGACATGCTGGGCGGCGACCTGCGGCTGGAAAGCCGGCTGG
GCGAGGGATCGCTGTTCCGCGTCGTGCTGATGATGCCGCATGTCTCCGGCATGGTGGACTGTGCCGCGCCGCGCCCTCGA
CCGGTGGGGTATCGGGGGGCAAGGCGGTCGCTGTTGCTCGTCGATGACGATGCCGACCATCTTGCCGTGCTGCGCTGCAC
GCTCGAATCCTGTGGGTTCGACGTTTCGCTGGCGCCCGACGGCGCGGCGGCGCTTGCTCTGGCTCACGCGCGCGCCTTCG
ATGCTGTCGTCCTGGACATTGCGATGCCGGGATTGTCGGGTTGGGAGGTCGCGGAAAGGCTGCGTGCCGCGCACGGGCAG
TCATTCAGGCTGGTCATGCTTTCCGCCAATGCCGAAGAGCGGCACGGGCCACGGGGCAAGGAGCCTGACCACGACCTGTT
CCTGATGAAGCCGGTTGAACTGTCCGCGCTGGTCGACTCGCTGGGCAAGCTGCTGGGGCTGGAGTGGATACTCTCCGAAG
GCGGCGGCGACACCGTGCTGGCCCAGCCGCGGATCGACGTGTCGGACAGCGCGCGGACACATGTCGATCGTCTGAAATCG
TTGGCGAGGATCGGCCACTTGCGAGGGTTGGAGGCGGAAATTCGCAGCATGCAGGAAACGGACACCGGGACGGCGCCACT
TGCCGCGCGCCTCTTCGATTGCCTCGACCGGTGCGACCTCGTGGCGATGCGGCGGGTGTTGGAGGGCATATGA

Upstream 100 bases:

>100_bases
GTTCGCGCCGCATACAAGGTGGGCGGCGCTCGGGGGTGCCTTCAATGGTCGCGTTCCGTGGGGTCGCAAGAAATCCGGTT
GCTGACGAAGGGCGGCTCGC

Downstream 100 bases:

>100_bases
CGACTGGCGAATACGAGCGGCGGGACACCGTGCTGGTGGTGGACGACGAGCCGGATTCGCTGCGTTTCCTTGCGGATACG
CTGGAGGGCGCGGGTATCCG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MIALPRFAALPSRGVPIAAAWAALAVALLIVDAVVPGESLALHGATLTSFCIFVLTCIRQARRDDDSQDTDREALRQELD
AAECASAAKSRYLASVSHEIRSPLNAIYGYAQLVEREGTVDPRDAARVIRRSAEHLTNLVEGLLDIASIEQGVVRIDSTV
ARLDALVEQVAEMFRPLAVQKGLAFRCDLPARLPEFVRMDERRVRQVLINLVSNAVKFTQAGEVVLAVRWSGEIATFEVR
DTGPGISPAHQETVFSPYQTGGVECGGGAGLGLAITRAIVDMLGGDLRLESRLGEGSLFRVVLMMPHVSGMVDCAAPRPR
PVGYRGARRSLLLVDDDADHLAVLRCTLESCGFDVSLAPDGAAALALAHARAFDAVVLDIAMPGLSGWEVAERLRAAHGQ
SFRLVMLSANAEERHGPRGKEPDHDLFLMKPVELSALVDSLGKLLGLEWILSEGGGDTVLAQPRIDVSDSARTHVDRLKS
LARIGHLRGLEAEIRSMQETDTGTAPLAARLFDCLDRCDLVAMRRVLEGI

Sequences:

>Translated_530_residues
MIALPRFAALPSRGVPIAAAWAALAVALLIVDAVVPGESLALHGATLTSFCIFVLTCIRQARRDDDSQDTDREALRQELD
AAECASAAKSRYLASVSHEIRSPLNAIYGYAQLVEREGTVDPRDAARVIRRSAEHLTNLVEGLLDIASIEQGVVRIDSTV
ARLDALVEQVAEMFRPLAVQKGLAFRCDLPARLPEFVRMDERRVRQVLINLVSNAVKFTQAGEVVLAVRWSGEIATFEVR
DTGPGISPAHQETVFSPYQTGGVECGGGAGLGLAITRAIVDMLGGDLRLESRLGEGSLFRVVLMMPHVSGMVDCAAPRPR
PVGYRGARRSLLLVDDDADHLAVLRCTLESCGFDVSLAPDGAAALALAHARAFDAVVLDIAMPGLSGWEVAERLRAAHGQ
SFRLVMLSANAEERHGPRGKEPDHDLFLMKPVELSALVDSLGKLLGLEWILSEGGGDTVLAQPRIDVSDSARTHVDRLKS
LARIGHLRGLEAEIRSMQETDTGTAPLAARLFDCLDRCDLVAMRRVLEGI
>Mature_530_residues
MIALPRFAALPSRGVPIAAAWAALAVALLIVDAVVPGESLALHGATLTSFCIFVLTCIRQARRDDDSQDTDREALRQELD
AAECASAAKSRYLASVSHEIRSPLNAIYGYAQLVEREGTVDPRDAARVIRRSAEHLTNLVEGLLDIASIEQGVVRIDSTV
ARLDALVEQVAEMFRPLAVQKGLAFRCDLPARLPEFVRMDERRVRQVLINLVSNAVKFTQAGEVVLAVRWSGEIATFEVR
DTGPGISPAHQETVFSPYQTGGVECGGGAGLGLAITRAIVDMLGGDLRLESRLGEGSLFRVVLMMPHVSGMVDCAAPRPR
PVGYRGARRSLLLVDDDADHLAVLRCTLESCGFDVSLAPDGAAALALAHARAFDAVVLDIAMPGLSGWEVAERLRAAHGQ
SFRLVMLSANAEERHGPRGKEPDHDLFLMKPVELSALVDSLGKLLGLEWILSEGGGDTVLAQPRIDVSDSARTHVDRLKS
LARIGHLRGLEAEIRSMQETDTGTAPLAARLFDCLDRCDLVAMRRVLEGI

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=342, Percent_Identity=33.9181286549708, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1788713, Length=382, Percent_Identity=29.8429319371728, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI87081816, Length=350, Percent_Identity=33.4285714285714, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI145693157, Length=235, Percent_Identity=35.7446808510638, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1789149, Length=247, Percent_Identity=32.7935222672065, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=34.8214285714286, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788549, Length=215, Percent_Identity=29.7674418604651, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1786600, Length=225, Percent_Identity=30.6666666666667, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=29.3617021276596, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790300, Length=249, Percent_Identity=29.718875502008, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=29.2887029288703, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787894, Length=237, Percent_Identity=28.6919831223629, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788393, Length=207, Percent_Identity=25.1207729468599, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=27.3127753303965, Blast_Score=62, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=73, Percent_Identity=45.2054794520548, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57169; Mature: 57169

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALPRFAALPSRGVPIAAAWAALAVALLIVDAVVPGESLALHGATLTSFCIFVLTCIRQ
CCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHH
ARRDDDSQDTDREALRQELDAAECASAAKSRYLASVSHEIRSPLNAIYGYAQLVEREGTV
HHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DPRDAARVIRRSAEHLTNLVEGLLDIASIEQGVVRIDSTVARLDALVEQVAEMFRPLAVQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGLAFRCDLPARLPEFVRMDERRVRQVLINLVSNAVKFTQAGEVVLAVRWSGEIATFEVR
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEE
DTGPGISPAHQETVFSPYQTGGVECGGGAGLGLAITRAIVDMLGGDLRLESRLGEGSLFR
CCCCCCCCCCHHHCCCCHHCCCEECCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCHHHH
VVLMMPHVSGMVDCAAPRPRPVGYRGARRSLLLVDDDADHLAVLRCTLESCGFDVSLAPD
HHHHHHCCCCCEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCC
GAAALALAHARAFDAVVLDIAMPGLSGWEVAERLRAAHGQSFRLVMLSANAEERHGPRGK
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCHHHCCCCCC
EPDHDLFLMKPVELSALVDSLGKLLGLEWILSEGGGDTVLAQPRIDVSDSARTHVDRLKS
CCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHH
LARIGHLRGLEAEIRSMQETDTGTAPLAARLFDCLDRCDLVAMRRVLEGI
HHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIALPRFAALPSRGVPIAAAWAALAVALLIVDAVVPGESLALHGATLTSFCIFVLTCIRQ
CCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHH
ARRDDDSQDTDREALRQELDAAECASAAKSRYLASVSHEIRSPLNAIYGYAQLVEREGTV
HHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DPRDAARVIRRSAEHLTNLVEGLLDIASIEQGVVRIDSTVARLDALVEQVAEMFRPLAVQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGLAFRCDLPARLPEFVRMDERRVRQVLINLVSNAVKFTQAGEVVLAVRWSGEIATFEVR
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEE
DTGPGISPAHQETVFSPYQTGGVECGGGAGLGLAITRAIVDMLGGDLRLESRLGEGSLFR
CCCCCCCCCCHHHCCCCHHCCCEECCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCHHHH
VVLMMPHVSGMVDCAAPRPRPVGYRGARRSLLLVDDDADHLAVLRCTLESCGFDVSLAPD
HHHHHHCCCCCEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCC
GAAALALAHARAFDAVVLDIAMPGLSGWEVAERLRAAHGQSFRLVMLSANAEERHGPRGK
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCHHHCCCCCC
EPDHDLFLMKPVELSALVDSLGKLLGLEWILSEGGGDTVLAQPRIDVSDSARTHVDRLKS
CCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHH
LARIGHLRGLEAEIRSMQETDTGTAPLAARLFDCLDRCDLVAMRRVLEGI
HHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]