BacMap

Definition	Novosphingobium aromaticivorans DSM 12444 chromosome, complete genome.
Accession	NC_007794
Length	3,561,584

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The map label for this gene is fabG [H]

Identifier: 87199581

GI number: 87199581

Start: 1622710

End: 1623423

Strand: Direct

Name: fabG [H]

Synonym: Saro_1564

Alternate gene names: 87199581

Gene position: 1622710-1623423 (Clockwise)

Preceding gene: 87199580

Following gene: 87199582

Centisome position: 45.56

GC content: 70.03

Gene sequence:

>714_bases
GTGCGGCCCCACGCCCTTGTTACCGGCGGCGCGCAGGGCATCGGCCGCGCCGTGGCCGAACTGCTTGCCGGGCAGGGCTG
GGATGTCACGGCCGCCGATCTCGACGAGGCGGCGCTGCGGCGGGCGTCAGGGCAGTGGAACGACATTTCCCCTGCCGTGC
TTGACGTCACCGCTTCTGCGCAGGTGGCCGCGCTCGTCGACCGGCTTCCACCGCTCGACGTGGTCGTCAATTGCGCCGGC
ATAGCGGCCGAACTCCTGCCGTTGAAGGACATCAGCCGCGCCGCGTTCGAACGAATGCTAAGGGTGAACGTTGGCGGCAC
CTTCCTGCTGGCGCGCGAGGCGGCCCGGCGGATGGAAGGGGGCGCAATCGTTGCCATCGCCTCGCGCGGCTATCTCGGCG
GGGCAGGGGCAGCGCACTATGTCGCGTCCAAGGCAGCGGTCGTCGGCATGGTCCGTTCGCTGGCGGTAGAACTGCGCTGG
CGCGGAATCAGCGTGAACGCGGTCGCTCCTGGCATGGTCGAGACACGCATGATCGATGACTTCACCTCCGAAATGCGCGC
CCGCCTTGCCCGGCTGGAACCCGGCGGTGGGCCCATGCCACCTGCGACGATCGCCGGTGCCGTCGCTTACCTCGCCTCTG
CGGCCGGGCGCGCGGTCAACGGGCAGGTCCTGCTGGTGGACGGTGGCAAGTCGCTCGGCGTCGCGCCATGCTGA

Upstream 100 bases:

>100_bases
CATCGTCCTCGACGATCTTCCGCGCCATGCCAGCGGCAAGTCCGACTACCGCCGCGCGACCGAACTCGCCGTGGCCCACC
TCGCCCTCGCGGCCTGACCG

Downstream 100 bases:

>100_bases
CCGTTCGCGCTCGGCCCGGCAGTCTGACCGATACCGCCGCACGTCTTGTCACTGCCGCAGGCATCCCGTCGGCCTTGGTC
GATGCCATGCCCCCACCGCG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MRPHALVTGGAQGIGRAVAELLAGQGWDVTAADLDEAALRRASGQWNDISPAVLDVTASAQVAALVDRLPPLDVVVNCAG
IAAELLPLKDISRAAFERMLRVNVGGTFLLAREAARRMEGGAIVAIASRGYLGGAGAAHYVASKAAVVGMVRSLAVELRW
RGISVNAVAPGMVETRMIDDFTSEMRARLARLEPGGGPMPPATIAGAVAYLASAAGRAVNGQVLLVDGGKSLGVAPC

Sequences:

>Translated_237_residues
MRPHALVTGGAQGIGRAVAELLAGQGWDVTAADLDEAALRRASGQWNDISPAVLDVTASAQVAALVDRLPPLDVVVNCAG
IAAELLPLKDISRAAFERMLRVNVGGTFLLAREAARRMEGGAIVAIASRGYLGGAGAAHYVASKAAVVGMVRSLAVELRW
RGISVNAVAPGMVETRMIDDFTSEMRARLARLEPGGGPMPPATIAGAVAYLASAAGRAVNGQVLLVDGGKSLGVAPC
>Mature_237_residues
MRPHALVTGGAQGIGRAVAELLAGQGWDVTAADLDEAALRRASGQWNDISPAVLDVTASAQVAALVDRLPPLDVVVNCAG
IAAELLPLKDISRAAFERMLRVNVGGTFLLAREAARRMEGGAIVAIASRGYLGGAGAAHYVASKAAVVGMVRSLAVELRW
RGISVNAVAPGMVETRMIDDFTSEMRARLARLEPGGGPMPPATIAGAVAYLASAAGRAVNGQVLLVDGGKSLGVAPC

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=34.6774193548387, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=35.4166666666667, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI19923817, Length=249, Percent_Identity=28.1124497991968, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=32, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI66933014, Length=222, Percent_Identity=27.9279279279279, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4758504, Length=248, Percent_Identity=32.258064516129, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=28.099173553719, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI59889578, Length=225, Percent_Identity=30.6666666666667, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI4503817, Length=211, Percent_Identity=29.3838862559242, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI7705925, Length=232, Percent_Identity=28.448275862069, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI83715985, Length=174, Percent_Identity=35.0574712643678, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787335, Length=236, Percent_Identity=34.7457627118644, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1790717, Length=238, Percent_Identity=31.0924369747899, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI87082160, Length=238, Percent_Identity=32.7731092436975, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=34.375, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786812, Length=245, Percent_Identity=33.0612244897959, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=32.0158102766798, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=30.7377049180328, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI87082100, Length=248, Percent_Identity=28.6290322580645, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI2367365, Length=232, Percent_Identity=34.051724137931, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787905, Length=238, Percent_Identity=30.672268907563, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=29.7959183673469, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787526, Length=245, Percent_Identity=28.1632653061224, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1789057, Length=207, Percent_Identity=31.4009661835749, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=240, Percent_Identity=32.9166666666667, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17555706, Length=236, Percent_Identity=32.6271186440678, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17538182, Length=245, Percent_Identity=31.0204081632653, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=29.2, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=238, Percent_Identity=34.0336134453782, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=26.6932270916335, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=243, Percent_Identity=27.5720164609054, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=27.3092369477912, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=31.0880829015544, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=256, Percent_Identity=28.515625, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=29.7297297297297, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=27.6923076923077, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=28.735632183908, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=259, Percent_Identity=30.1158301158301, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=29.0836653386454, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=30.0380228136882, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=256, Percent_Identity=28.90625, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=257, Percent_Identity=28.0155642023346, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=259, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=254, Percent_Identity=26.3779527559055, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=27.4193548387097, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=29.5019157088123, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=27.5193798449612, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=28.030303030303, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI17737361, Length=248, Percent_Identity=34.6774193548387, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24639444, Length=238, Percent_Identity=32.7731092436975, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24643142, Length=235, Percent_Identity=31.9148936170213, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI23397609, Length=239, Percent_Identity=31.7991631799163, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356301, Length=225, Percent_Identity=28, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21357041, Length=243, Percent_Identity=30.0411522633745, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355319, Length=240, Percent_Identity=25.8333333333333, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24227; Mature: 24227

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPHALVTGGAQGIGRAVAELLAGQGWDVTAADLDEAALRRASGQWNDISPAVLDVTASA
CCCCEEEECCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCCCCHHEEEEECCH
QVAALVDRLPPLDVVVNCAGIAAELLPLKDISRAAFERMLRVNVGGTFLLAREAARRMEG
HHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
GAIVAIASRGYLGGAGAAHYVASKAAVVGMVRSLAVELRWRGISVNAVAPGMVETRMIDD
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCEEECCCCCCHHHHHHHHH
FTSEMRARLARLEPGGGPMPPATIAGAVAYLASAAGRAVNGQVLLVDGGKSLGVAPC
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MRPHALVTGGAQGIGRAVAELLAGQGWDVTAADLDEAALRRASGQWNDISPAVLDVTASA
CCCCEEEECCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCCCCHHEEEEECCH
QVAALVDRLPPLDVVVNCAGIAAELLPLKDISRAAFERMLRVNVGGTFLLAREAARRMEG
HHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
GAIVAIASRGYLGGAGAAHYVASKAAVVGMVRSLAVELRWRGISVNAVAPGMVETRMIDD
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCEEECCCCCCHHHHHHHHH
FTSEMRARLARLEPGGGPMPPATIAGAVAYLASAAGRAVNGQVLLVDGGKSLGVAPC
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA