Click here to switch to the map view.

The map label for this gene is dsbE [H]

Identifier: 87199412

GI number: 87199412

Start: 1435401

End: 1435952

Strand: Direct

Name: dsbE [H]

Synonym: Saro_1391

Alternate gene names: 87199412

Gene position: 1435401-1435952 (Clockwise)

Preceding gene: 87199411

Following gene: 87199413

Centisome position: 40.3

GC content: 66.67

Gene sequence:

>552_bases
GTGACGGAACCCAAGGGCAAGCGCCCCGGCCTCGCGATCTGGCTTCCGCTCGCGCTGTTCGGTGCGTTCTTCGCGCTGGT
GATCTGGGGGCTCGTGCGCCCGGCCGACCGCGAAGTGGCCAGCGCCTTCATCGGCAAGCCGCTGCCGCAGTTCTCGCTCC
AGCCCGCGACCGACGATCGCCCGGGCCTGTCGACGGCGGACTTCCGCGACGGCAAGCCCCGTCTGCTCAACGTCTTTGCA
AGCTGGTGCGTCCCCTGCGCGATCGAATCTCCGCAGCTCGATGCACTCGCCAGGCAGGGCGTGGAGATCAACGGCGTCGC
CATTCGCGACCGCAAGGACGACGTCGCCCGCTTCCTCGCCACCAACGGTAATCCCTTCGCCAAGATCGGCAAGGACGACC
TCTCGGAAGTGCAGCTCGGCATCGGGTCCTCCGGCGTTCCAGAGACCTTCGTTATCGATGGCAAGGGCGTGATCCGCTAC
CAGCACATCGGCGAAATCCGGCCCGAGGACATGGGTCTGATCCTCGGCAAGCTGAAGGAGGCCGCGCAATGA

Upstream 100 bases:

>100_bases
GCGGCGTTCTGGCGCTTCTGGGCCGGGTGGCGCATGATGTTCGCCGCCTGCGCGCAGGCGGCAAGATTGCATATCGCCGG
GCCCGGATGGAGCAGGTGAA

Downstream 100 bases:

>100_bases
GCGTTTCGCGTTCGCTAGGGCTTCTGGCCGCCGCCCTGCTGCTGAGCCTCACCGCTCCGCTTGCCGCGCAGGACACTATG
CCGCCCGCGCCTTACGCCTA

Product: periplasmic protein thiol

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CcmG [H]

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MTEPKGKRPGLAIWLPLALFGAFFALVIWGLVRPADREVASAFIGKPLPQFSLQPATDDRPGLSTADFRDGKPRLLNVFA
SWCVPCAIESPQLDALARQGVEINGVAIRDRKDDVARFLATNGNPFAKIGKDDLSEVQLGIGSSGVPETFVIDGKGVIRY
QHIGEIRPEDMGLILGKLKEAAQ

Sequences:

>Translated_183_residues
MTEPKGKRPGLAIWLPLALFGAFFALVIWGLVRPADREVASAFIGKPLPQFSLQPATDDRPGLSTADFRDGKPRLLNVFA
SWCVPCAIESPQLDALARQGVEINGVAIRDRKDDVARFLATNGNPFAKIGKDDLSEVQLGIGSSGVPETFVIDGKGVIRY
QHIGEIRPEDMGLILGKLKEAAQ
>Mature_182_residues
TEPKGKRPGLAIWLPLALFGAFFALVIWGLVRPADREVASAFIGKPLPQFSLQPATDDRPGLSTADFRDGKPRLLNVFAS
WCVPCAIESPQLDALARQGVEINGVAIRDRKDDVARFLATNGNPFAKIGKDDLSEVQLGIGSSGVPETFVIDGKGVIRYQ
HIGEIRPEDMGLILGKLKEAAQ

Specific function: Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=180, Percent_Identity=39.4444444444444, Blast_Score=113, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 19792; Mature: 19661

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPKGKRPGLAIWLPLALFGAFFALVIWGLVRPADREVASAFIGKPLPQFSLQPATDDR
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
PGLSTADFRDGKPRLLNVFASWCVPCAIESPQLDALARQGVEINGVAIRDRKDDVARFLA
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEECCEEEECCHHHHHHHHH
TNGNPFAKIGKDDLSEVQLGIGSSGVPETFVIDGKGVIRYQHIGEIRPEDMGLILGKLKE
CCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHH
AAQ
HCC
>Mature Secondary Structure 
TEPKGKRPGLAIWLPLALFGAFFALVIWGLVRPADREVASAFIGKPLPQFSLQPATDDR
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
PGLSTADFRDGKPRLLNVFASWCVPCAIESPQLDALARQGVEINGVAIRDRKDDVARFLA
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEECCEEEECCHHHHHHHHH
TNGNPFAKIGKDDLSEVQLGIGSSGVPETFVIDGKGVIRYQHIGEIRPEDMGLILGKLKE
CCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHH
AAQ
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]