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The map label for this gene is surA [H]

Identifier: 87198910

GI number: 87198910

Start: 943788

End: 945158

Strand: Reverse

Name: surA [H]

Synonym: Saro_0888

Alternate gene names: 87198910

Gene position: 945158-943788 (Counterclockwise)

Preceding gene: 87198911

Following gene: 87198909

Centisome position: 26.54

GC content: 66.52

Gene sequence:

>1371_bases
ATGACGTCCAAGCTGAACATTTCCCGCAAGGCGGCCATTTCCGCATTTGGCCGCTCGCTGGGCACCACTGCGATGGCCCT
TGCCGCATTCGCCACCGCCACTTCGCCCGTGCTGGCGCAGGGCGCGAACGCCCCGCTGAACATCCCGGCGAACCCGCAGA
TGTTCGGCACGAACGATCCCAACGTACGCCGCGCAACGGCCATCGTGAACGGCGAGATCATCACCGGCACCGACGTCGAA
CAGCGGCTTGCGCTGATCGTCTCGGCCAACGGCGGCAAGATCGACGGCGAGGAAAAGGAGCGCCTGCGCATGCAGGTGCT
GCGCAACCTGATCGACGAGACGCTCCAGATCCAGGAAGCCAAGGCCGCCGACGTCCCCGCCGACGACGGACAGGTCGACG
CCAGCTACGAACGCGTCGCCACGCAGAACTTCGGCCAGTCGGCCGATGCTCTGGAAAAGTACCTTGCCCGCATCGGCTCG
TCCGCCGCTTCGCTCAAGCGGCAGATCCGCGGCGAGATCGCCTGGCAGAACCTGCTGCGCCGCAACGTCCAGCCGTTCGT
CAACGTCTCCGAAGGCGAAGTGCAGGAAGCCATGCAGCGCCTTCAGGCGTCCAAGGGCACCGAGGAATATCGCATCGGCG
AAATCTTCCTCGCCGCGACCGAGGAGAACAAGCCGCAGGTCTTCGCCAACGCCGAGAAGATCGTCGAGCAGCTCAAGCAG
GGCGGCAGCTTCGTCGCCTATGCGCGCCAGTATTCCGAAGCCTCGACGGCGGCCGTGGGCGGCGACCTTGGCTGGATTCG
CCTGGCCCAGTTGCCCACCGAACTGGCGACGACCGCCGCCTCCATGGGCCCCGGCCAGCTTGCCGGCCCGGTCGAGATTC
GCGGCGGCTTCTCGATCCTCTACCTGATCGACAAGCGCCAGGTGCTGACCGCCGATCCCCGCGACGCGCTGCTGAGCCTC
AAGCAGATCTCGATCGAGTTTCCCAAGGGCGCGACCAACGAGATCGCGACCAAGCGCGCGGCCGAGTTTGCCGCCGCCGT
CAAGGCGATCAAGGGCTGCGGCGATGCCGAGGCCCAGGCCAACAAGATCGGCGCGACCGTCGTCGCCAACGACCAGATCA
AGGCGCGCGACCTGCCGGGCGCGCTCCAGGAAACGCTCCTCAACCTGCCCATCGGCCAGACCACGCCGCCCTTCGGTTCC
ATCGAGGAAGGCGTGCGCGTGCTGATGCTGTGCGGGCGCGACGATCCGCAGGTCAACAGCGGCCCCAGCTTCGACGAGAT
GATGGCCCAGATCGAGGACGACCGCGTCAACAAGCGCGCCCAGACCTATCTGCGTGACCTTCGCCGCGACGCGGTGATCG
AGTACAACTGA

Upstream 100 bases:

>100_bases
TAGGCCACTCAGCTTGGGTTAAGCCGCGCGCGGCCACAGACCCGAGGATATCAGAAGGCCGCCAACCGAGCGCCAGTTCG
ACAGGACCATTTCCAAGACC

Downstream 100 bases:

>100_bases
GGAAGTCCTGGGACTGGCCGGAACACTCTCGGCCAGTACCCTCGCAATGCGCGGCGGCTTGGTCTAGGGGTCGGCCATGA
CCGCTCTTGCTCCACTTGCG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MTSKLNISRKAAISAFGRSLGTTAMALAAFATATSPVLAQGANAPLNIPANPQMFGTNDPNVRRATAIVNGEIITGTDVE
QRLALIVSANGGKIDGEEKERLRMQVLRNLIDETLQIQEAKAADVPADDGQVDASYERVATQNFGQSADALEKYLARIGS
SAASLKRQIRGEIAWQNLLRRNVQPFVNVSEGEVQEAMQRLQASKGTEEYRIGEIFLAATEENKPQVFANAEKIVEQLKQ
GGSFVAYARQYSEASTAAVGGDLGWIRLAQLPTELATTAASMGPGQLAGPVEIRGGFSILYLIDKRQVLTADPRDALLSL
KQISIEFPKGATNEIATKRAAEFAAAVKAIKGCGDAEAQANKIGATVVANDQIKARDLPGALQETLLNLPIGQTTPPFGS
IEEGVRVLMLCGRDDPQVNSGPSFDEMMAQIEDDRVNKRAQTYLRDLRRDAVIEYN

Sequences:

>Translated_456_residues
MTSKLNISRKAAISAFGRSLGTTAMALAAFATATSPVLAQGANAPLNIPANPQMFGTNDPNVRRATAIVNGEIITGTDVE
QRLALIVSANGGKIDGEEKERLRMQVLRNLIDETLQIQEAKAADVPADDGQVDASYERVATQNFGQSADALEKYLARIGS
SAASLKRQIRGEIAWQNLLRRNVQPFVNVSEGEVQEAMQRLQASKGTEEYRIGEIFLAATEENKPQVFANAEKIVEQLKQ
GGSFVAYARQYSEASTAAVGGDLGWIRLAQLPTELATTAASMGPGQLAGPVEIRGGFSILYLIDKRQVLTADPRDALLSL
KQISIEFPKGATNEIATKRAAEFAAAVKAIKGCGDAEAQANKIGATVVANDQIKARDLPGALQETLLNLPIGQTTPPFGS
IEEGVRVLMLCGRDDPQVNSGPSFDEMMAQIEDDRVNKRAQTYLRDLRRDAVIEYN
>Mature_455_residues
TSKLNISRKAAISAFGRSLGTTAMALAAFATATSPVLAQGANAPLNIPANPQMFGTNDPNVRRATAIVNGEIITGTDVEQ
RLALIVSANGGKIDGEEKERLRMQVLRNLIDETLQIQEAKAADVPADDGQVDASYERVATQNFGQSADALEKYLARIGSS
AASLKRQIRGEIAWQNLLRRNVQPFVNVSEGEVQEAMQRLQASKGTEEYRIGEIFLAATEENKPQVFANAEKIVEQLKQG
GSFVAYARQYSEASTAAVGGDLGWIRLAQLPTELATTAASMGPGQLAGPVEIRGGFSILYLIDKRQVLTADPRDALLSLK
QISIEFPKGATNEIATKRAAEFAAAVKAIKGCGDAEAQANKIGATVVANDQIKARDLPGALQETLLNLPIGQTTPPFGSI
EEGVRVLMLCGRDDPQVNSGPSFDEMMAQIEDDRVNKRAQTYLRDLRRDAVIEYN

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=210, Percent_Identity=25.7142857142857, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 49042; Mature: 48911

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSKLNISRKAAISAFGRSLGTTAMALAAFATATSPVLAQGANAPLNIPANPQMFGTNDP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEECCCCCCCCCCCCC
NVRRATAIVNGEIITGTDVEQRLALIVSANGGKIDGEEKERLRMQVLRNLIDETLQIQEA
CCEEEEEEECCEEEECCCHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KAADVPADDGQVDASYERVATQNFGQSADALEKYLARIGSSAASLKRQIRGEIAWQNLLR
HCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
RNVQPFVNVSEGEVQEAMQRLQASKGTEEYRIGEIFLAATEENKPQVFANAEKIVEQLKQ
CCCCCCEECCHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCEEECHHHHHHHHHC
GGSFVAYARQYSEASTAAVGGDLGWIRLAQLPTELATTAASMGPGQLAGPVEIRGGFSIL
CCCEEEHHHHHHHHHHHHCCCCCHHHHHHHCHHHHHHHHHCCCCCCCCCCEEECCCEEEE
YLIDKRQVLTADPRDALLSLKQISIEFPKGATNEIATKRAAEFAAAVKAIKGCGDAEAQA
EEEECCCEECCCCHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHH
NKIGATVVANDQIKARDLPGALQETLLNLPIGQTTPPFGSIEEGVRVLMLCGRDDPQVNS
HHCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHCCEEEEEECCCCCCCCC
GPSFDEMMAQIEDDRVNKRAQTYLRDLRRDAVIEYN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TSKLNISRKAAISAFGRSLGTTAMALAAFATATSPVLAQGANAPLNIPANPQMFGTNDP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEECCCCCCCCCCCCC
NVRRATAIVNGEIITGTDVEQRLALIVSANGGKIDGEEKERLRMQVLRNLIDETLQIQEA
CCEEEEEEECCEEEECCCHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KAADVPADDGQVDASYERVATQNFGQSADALEKYLARIGSSAASLKRQIRGEIAWQNLLR
HCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
RNVQPFVNVSEGEVQEAMQRLQASKGTEEYRIGEIFLAATEENKPQVFANAEKIVEQLKQ
CCCCCCEECCHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCEEECHHHHHHHHHC
GGSFVAYARQYSEASTAAVGGDLGWIRLAQLPTELATTAASMGPGQLAGPVEIRGGFSIL
CCCEEEHHHHHHHHHHHHCCCCCHHHHHHHCHHHHHHHHHCCCCCCCCCCEEECCCEEEE
YLIDKRQVLTADPRDALLSLKQISIEFPKGATNEIATKRAAEFAAAVKAIKGCGDAEAQA
EEEECCCEECCCCHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHH
NKIGATVVANDQIKARDLPGALQETLLNLPIGQTTPPFGSIEEGVRVLMLCGRDDPQVNS
HHCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHCCEEEEEECCCCCCCCC
GPSFDEMMAQIEDDRVNKRAQTYLRDLRRDAVIEYN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA