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The map label for this gene is lptD [H]

Identifier: 87198911

GI number: 87198911

Start: 945287

End: 947557

Strand: Reverse

Name: lptD [H]

Synonym: Saro_0889

Alternate gene names: 87198911

Gene position: 947557-945287 (Counterclockwise)

Preceding gene: 87198915

Following gene: 87198910

Centisome position: 26.6

GC content: 67.68

Gene sequence:

>2271_bases
ATGCAACCCGCCCGGCGGCCGCAGCCGCAAGCCCTCGATCGACGCTTGCGCCTTGCGCGCGCGGCCCTCTCGGCCTCGGG
CCTCGCGCTGGCCGCGATGCTCGCACCGGCGGCAGCCGCGCAGGACGCTTCGATCAACGCCGAATCGTCGCCCGACGATG
TCGTCCGCTTCGAAGCCGACAAGGTCCGCTACGACAGCAACGCCGAACTGGTGACCGCCACCGGCAATGTCGTGCTGCGC
CACGAGGACCAGACCGTGCGCGCCGACAACGTGACCTGGGACCGAAACAGCGGCCAGATCGTCGCCAATGGCAACATCCG
CTTCGTCGATGTCGACGGCAATGTCGTGTACACCGAGAAGGTCGAGCTGACCGACGAGTTCAAGGCAGGGGCTATCGAGG
ACCTGCTGGTCGTGCTGCGCAGCGGAGGCCGTCTTGCCGCCGAACGCGGCAGCCGCGACGCCGAAGGCAACATGACGCTC
GAGACCGCCGCCTATTCGGGTTGCGCGGTCGAGGACGAAAAGGGCTGCCCCAGGAAGCCGAGCTGGGAAGTGACCGCCAC
GCGCGTCTACTTCGACGCCAAGGAGCGGCGGGTGAAGTACAAGGGCGCCACGCTGCACCTGTTCGGCGTGCCGATCCTGC
CCTTGCCCGGGCTTGGACACACCTCGGACTTCCGCGCGGAGACGGGGCTGCTCATCCCCGACTTCCGGCTGGGCGCGTCG
AACGGCGCGGAAATCAGCGAGACCTGGTACTGGCGCATCGCCGACAACCGCGACCTTGCGGTGACCGGTACGTTCTACAC
CGGCGCACTGCCGATGCTGACGACCAAGTATCGCCACCTGACCGATCTCGGCGCGTTCCAGATTACCGGCTACGCCACGC
GCAGCTCGCGCATTCCGCTGGGCAGCAATGCGGCGGGGACCGCCAATGCCAGCCAGCAATCCTGGCGCGGCTACGTCGAT
TCGAACGGCAAGCTGCAATTCTCGCCGGAATGGAGCCTGACCGGCAACCTGCGCCTGGCATCGGACCGCACGTTCCTGCG
CCGCTACGACATCAGCCGCGACGACCGCCTGCGCTCCTCGCTCAACCTCGAGCGGATCAGCCCCGACAGCTACCTCAGCA
TCGCCGGGTGGGTGACGCAGACGGTGCGCGTCAACGACCCGCAGGGCATGGTGCCGCTGGCCCTGCCCGCCATCGACTAC
CGCCGCCGCCTGGCGTTCGACGGCATTCCGGGCCGGTTCGAGCTGGAGGCCAACAGCCTCGCCATCGTGCGCACCGCCGG
ACAGGACAGCCAGCGCGCCTTTGCCCGCGCGCAGTGGGATCTGCGCACGATCACCGGCATGGGGCAGGAAGTGACCCTCA
CCGGGCTCCTGCGCGGCGACGTCTATCACAGCAGCGACAACGAACTCACCACGACCGAGGTCTATCGCGGCCTTTCGGGC
TGGCAGACGCGCGGCATCGCCACCGCCGCGCTCGACGTGAAGTGGCCCTTCGTGGGCGAGGTCTTCGGCGGAAGCCAGGT
GCTGACCCCGCGCTTCCAGGTCGTCGCGACGCCGGGCGTGCGCAACTTCGAGATTCCCAACGAGGATTCGCGCTCGGTCG
ACCTCGAGGACACCAACCTCTTCGCGCTCAACCGCTTTCCCGGCCACGACCGGATCGAGGACGGGGTGCGCTTCACCTAT
GGCTTCGACTGGCAGTTCCAGCGGCCGGGCCTGCGCGTCGCGACGACGATCGGGCAGAGCTACCGCCTGTCCAGCCAGAA
ATCGCTCCTGCCGGAAGGCACCGGGCTCACCAGCCGGGCATCGGACTACGTTGGGCGGACGACGGTGCGCTTTGGCGACG
TGATCAAGTTCACGCACCGCTTCCGGCTCGACAAGGACAGCCTGGCGCTACGCCGCAACGAGTTCGACGCGACGCTGGGC
GATCATCGCCGCTATGTCGAGGTCGGCTATCTCAAGCTCAACCGCAACATCGCCTCGACCTTCGAGGACCTGCAGGACCG
CGAGGAGCTGCGCTTTGCCGCGCGCACGCCGATCACGCGGACGTTCTCCGTCTTCGCCTCGGGCATCGTCAACCTGACCG
ACCGCAACGAGGATCCGACGCTGACCTCGGACGGCTTCCAGATGCTGCGGCACCGGATCGGCGTCGCCTATACCGACGAC
TGCCTCGACCTGTCGTTCACCTGGCGGCGCGACTACGTGACAACCGGCGACGCCGCGCGCGGCAACTCGTTCCAGGTCTC
GCTCTCGCTCAAGAACCTCGGGGTGAAGTAA

Upstream 100 bases:

>100_bases
CGGGAACTCCTGTCGGAAAGACGTCACGCTTCGGCGCGGAACGGCCAAGGCGAAAATTGTGGAATTGCAGTTAGGGTGCA
CTGGTGCGATAGGCAAGCGC

Downstream 100 bases:

>100_bases
CGCCTCGCACTTGCCCTTTCGCGCCCGATAGGCCACTCAGCTTGGGTTAAGCCGCGCGCGGCCACAGACCCGAGGATATC
AGAAGGCCGCCAACCGAGCG

Product: organic solvent tolerance protein

Products: NA

Alternate protein names: Organic solvent tolerance protein [H]

Number of amino acids: Translated: 756; Mature: 756

Protein sequence:

>756_residues
MQPARRPQPQALDRRLRLARAALSASGLALAAMLAPAAAAQDASINAESSPDDVVRFEADKVRYDSNAELVTATGNVVLR
HEDQTVRADNVTWDRNSGQIVANGNIRFVDVDGNVVYTEKVELTDEFKAGAIEDLLVVLRSGGRLAAERGSRDAEGNMTL
ETAAYSGCAVEDEKGCPRKPSWEVTATRVYFDAKERRVKYKGATLHLFGVPILPLPGLGHTSDFRAETGLLIPDFRLGAS
NGAEISETWYWRIADNRDLAVTGTFYTGALPMLTTKYRHLTDLGAFQITGYATRSSRIPLGSNAAGTANASQQSWRGYVD
SNGKLQFSPEWSLTGNLRLASDRTFLRRYDISRDDRLRSSLNLERISPDSYLSIAGWVTQTVRVNDPQGMVPLALPAIDY
RRRLAFDGIPGRFELEANSLAIVRTAGQDSQRAFARAQWDLRTITGMGQEVTLTGLLRGDVYHSSDNELTTTEVYRGLSG
WQTRGIATAALDVKWPFVGEVFGGSQVLTPRFQVVATPGVRNFEIPNEDSRSVDLEDTNLFALNRFPGHDRIEDGVRFTY
GFDWQFQRPGLRVATTIGQSYRLSSQKSLLPEGTGLTSRASDYVGRTTVRFGDVIKFTHRFRLDKDSLALRRNEFDATLG
DHRRYVEVGYLKLNRNIASTFEDLQDREELRFAARTPITRTFSVFASGIVNLTDRNEDPTLTSDGFQMLRHRIGVAYTDD
CLDLSFTWRRDYVTTGDAARGNSFQVSLSLKNLGVK

Sequences:

>Translated_756_residues
MQPARRPQPQALDRRLRLARAALSASGLALAAMLAPAAAAQDASINAESSPDDVVRFEADKVRYDSNAELVTATGNVVLR
HEDQTVRADNVTWDRNSGQIVANGNIRFVDVDGNVVYTEKVELTDEFKAGAIEDLLVVLRSGGRLAAERGSRDAEGNMTL
ETAAYSGCAVEDEKGCPRKPSWEVTATRVYFDAKERRVKYKGATLHLFGVPILPLPGLGHTSDFRAETGLLIPDFRLGAS
NGAEISETWYWRIADNRDLAVTGTFYTGALPMLTTKYRHLTDLGAFQITGYATRSSRIPLGSNAAGTANASQQSWRGYVD
SNGKLQFSPEWSLTGNLRLASDRTFLRRYDISRDDRLRSSLNLERISPDSYLSIAGWVTQTVRVNDPQGMVPLALPAIDY
RRRLAFDGIPGRFELEANSLAIVRTAGQDSQRAFARAQWDLRTITGMGQEVTLTGLLRGDVYHSSDNELTTTEVYRGLSG
WQTRGIATAALDVKWPFVGEVFGGSQVLTPRFQVVATPGVRNFEIPNEDSRSVDLEDTNLFALNRFPGHDRIEDGVRFTY
GFDWQFQRPGLRVATTIGQSYRLSSQKSLLPEGTGLTSRASDYVGRTTVRFGDVIKFTHRFRLDKDSLALRRNEFDATLG
DHRRYVEVGYLKLNRNIASTFEDLQDREELRFAARTPITRTFSVFASGIVNLTDRNEDPTLTSDGFQMLRHRIGVAYTDD
CLDLSFTWRRDYVTTGDAARGNSFQVSLSLKNLGVK
>Mature_756_residues
MQPARRPQPQALDRRLRLARAALSASGLALAAMLAPAAAAQDASINAESSPDDVVRFEADKVRYDSNAELVTATGNVVLR
HEDQTVRADNVTWDRNSGQIVANGNIRFVDVDGNVVYTEKVELTDEFKAGAIEDLLVVLRSGGRLAAERGSRDAEGNMTL
ETAAYSGCAVEDEKGCPRKPSWEVTATRVYFDAKERRVKYKGATLHLFGVPILPLPGLGHTSDFRAETGLLIPDFRLGAS
NGAEISETWYWRIADNRDLAVTGTFYTGALPMLTTKYRHLTDLGAFQITGYATRSSRIPLGSNAAGTANASQQSWRGYVD
SNGKLQFSPEWSLTGNLRLASDRTFLRRYDISRDDRLRSSLNLERISPDSYLSIAGWVTQTVRVNDPQGMVPLALPAIDY
RRRLAFDGIPGRFELEANSLAIVRTAGQDSQRAFARAQWDLRTITGMGQEVTLTGLLRGDVYHSSDNELTTTEVYRGLSG
WQTRGIATAALDVKWPFVGEVFGGSQVLTPRFQVVATPGVRNFEIPNEDSRSVDLEDTNLFALNRFPGHDRIEDGVRFTY
GFDWQFQRPGLRVATTIGQSYRLSSQKSLLPEGTGLTSRASDYVGRTTVRFGDVIKFTHRFRLDKDSLALRRNEFDATLG
DHRRYVEVGYLKLNRNIASTFEDLQDREELRFAARTPITRTFSVFASGIVNLTDRNEDPTLTSDGFQMLRHRIGVAYTDD
CLDLSFTWRRDYVTTGDAARGNSFQVSLSLKNLGVK

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis [H]

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family [H]

Homologues:

None

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020889
- InterPro:   IPR007543 [H]

Pfam domain/function: PF04453 OstA_C [H]

EC number: NA

Molecular weight: Translated: 84031; Mature: 84031

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPARRPQPQALDRRLRLARAALSASGLALAAMLAPAAAAQDASINAESSPDDVVRFEAD
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHCCCCCCCCCCCCCCEEEEEHH
KVRYDSNAELVTATGNVVLRHEDQTVRADNVTWDRNSGQIVANGNIRFVDVDGNVVYTEK
HEEECCCCEEEEECCCEEEEECCCEEEECCEEEECCCCEEEECCCEEEEEECCCEEEEEE
VELTDEFKAGAIEDLLVVLRSGGRLAAERGSRDAEGNMTLETAAYSGCAVEDEKGCPRKP
EEECCHHCCCCHHHHHHHHHCCCEEEHHCCCCCCCCCEEEEEECCCCCCEECCCCCCCCC
SWEVTATRVYFDAKERRVKYKGATLHLFGVPILPLPGLGHTSDFRAETGLLIPDFRLGAS
CCEEEEEEEEEECHHCEEEECCCEEEEECCCEECCCCCCCCCCCCCCCCEEECCEEECCC
NGAEISETWYWRIADNRDLAVTGTFYTGALPMLTTKYRHLTDLGAFQITGYATRSSRIPL
CCCCCCEEEEEEEECCCCEEEEEEHHHCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCC
GSNAAGTANASQQSWRGYVDSNGKLQFSPEWSLTGNLRLASDRTFLRRYDISRDDRLRSS
CCCCCCCCCCCHHHCCCEECCCCEEEECCCCCEEECEEEECCCEEEHHCCCCHHHHHHHH
LNLERISPDSYLSIAGWVTQTVRVNDPQGMVPLALPAIDYRRRLAFDGIPGRFELEANSL
CCCEEECCCCEEEEEEEEEEEEEECCCCCCCEEEECCHHHHHHHCCCCCCCEEEEECCCE
AIVRTAGQDSQRAFARAQWDLRTITGMGQEVTLTGLLRGDVYHSSDNELTTTEVYRGLSG
EEEEECCCCHHHHHHHHCCCEEHHHCCCCEEEEEEEEECCEEECCCCCEEHHHHHCCCCC
WQTRGIATAALDVKWPFVGEVFGGSQVLTPRFQVVATPGVRNFEIPNEDSRSVDLEDTNL
CCCCCEEEEEEEEECCEEEEECCCCEEECCCEEEEECCCCCCCCCCCCCCCEEECCCCCE
FALNRFPGHDRIEDGVRFTYGFDWQFQRPGLRVATTIGQSYRLSSQKSLLPEGTGLTSRA
EEEECCCCCCCCCCCEEEEEEECEEECCCCCEEEEECCCCEECCCCCCCCCCCCCCCCCH
SDYVGRTTVRFGDVIKFTHRFRLDKDSLALRRNEFDATLGDHRRYVEVGYLKLNRNIAST
HHHCCCEEEEHHHHHEEHHHEECCCHHHHEECCCCCCCCCCCCEEEEEEEEEECCCHHHH
FEDLQDREELRFAARTPITRTFSVFASGIVNLTDRNEDPTLTSDGFQMLRHRIGVAYTDD
HHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHCCCEEECC
CLDLSFTWRRDYVTTGDAARGNSFQVSLSLKNLGVK
CEEEEEEEECCEEECCCCCCCCEEEEEEEHHCCCCC
>Mature Secondary Structure
MQPARRPQPQALDRRLRLARAALSASGLALAAMLAPAAAAQDASINAESSPDDVVRFEAD
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHCCCCCCCCCCCCCCEEEEEHH
KVRYDSNAELVTATGNVVLRHEDQTVRADNVTWDRNSGQIVANGNIRFVDVDGNVVYTEK
HEEECCCCEEEEECCCEEEEECCCEEEECCEEEECCCCEEEECCCEEEEEECCCEEEEEE
VELTDEFKAGAIEDLLVVLRSGGRLAAERGSRDAEGNMTLETAAYSGCAVEDEKGCPRKP
EEECCHHCCCCHHHHHHHHHCCCEEEHHCCCCCCCCCEEEEEECCCCCCEECCCCCCCCC
SWEVTATRVYFDAKERRVKYKGATLHLFGVPILPLPGLGHTSDFRAETGLLIPDFRLGAS
CCEEEEEEEEEECHHCEEEECCCEEEEECCCEECCCCCCCCCCCCCCCCEEECCEEECCC
NGAEISETWYWRIADNRDLAVTGTFYTGALPMLTTKYRHLTDLGAFQITGYATRSSRIPL
CCCCCCEEEEEEEECCCCEEEEEEHHHCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCC
GSNAAGTANASQQSWRGYVDSNGKLQFSPEWSLTGNLRLASDRTFLRRYDISRDDRLRSS
CCCCCCCCCCCHHHCCCEECCCCEEEECCCCCEEECEEEECCCEEEHHCCCCHHHHHHHH
LNLERISPDSYLSIAGWVTQTVRVNDPQGMVPLALPAIDYRRRLAFDGIPGRFELEANSL
CCCEEECCCCEEEEEEEEEEEEEECCCCCCCEEEECCHHHHHHHCCCCCCCEEEEECCCE
AIVRTAGQDSQRAFARAQWDLRTITGMGQEVTLTGLLRGDVYHSSDNELTTTEVYRGLSG
EEEEECCCCHHHHHHHHCCCEEHHHCCCCEEEEEEEEECCEEECCCCCEEHHHHHCCCCC
WQTRGIATAALDVKWPFVGEVFGGSQVLTPRFQVVATPGVRNFEIPNEDSRSVDLEDTNL
CCCCCEEEEEEEEECCEEEEECCCCEEECCCEEEEECCCCCCCCCCCCCCCEEECCCCCE
FALNRFPGHDRIEDGVRFTYGFDWQFQRPGLRVATTIGQSYRLSSQKSLLPEGTGLTSRA
EEEECCCCCCCCCCCEEEEEEECEEECCCCCEEEEECCCCEECCCCCCCCCCCCCCCCCH
SDYVGRTTVRFGDVIKFTHRFRLDKDSLALRRNEFDATLGDHRRYVEVGYLKLNRNIAST
HHHCCCEEEEHHHHHEEHHHEECCCHHHHEECCCCCCCCCCCCEEEEEEEEEECCCHHHH
FEDLQDREELRFAARTPITRTFSVFASGIVNLTDRNEDPTLTSDGFQMLRHRIGVAYTDD
HHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHCCCEEECC
CLDLSFTWRRDYVTTGDAARGNSFQVSLSLKNLGVK
CEEEEEEEECCEEECCCCCCCCEEEEEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA