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The map label for this gene is pdxA [H]

Identifier: 87198909

GI number: 87198909

Start: 942704

End: 943711

Strand: Reverse

Name: pdxA [H]

Synonym: Saro_0887

Alternate gene names: 87198909

Gene position: 943711-942704 (Counterclockwise)

Preceding gene: 87198910

Following gene: 87198908

Centisome position: 26.5

GC content: 71.13

Gene sequence:

>1008_bases
ATGACCGCTCTTGCTCCACTTGCGCTGACCATCGGCGATCCGGCCGGCGTCGGGCCGGAACTTGCCGCCGCCGCCTGGGC
GCTCAGCGATGCCGAGGCGCTACTCCCGTTCTTCGTGGTCGGCTCTGCCCGGGTGGTGGAAGAGGCCGCCAGGCGGCGCG
GCATCACCGTTCCGGTCTGCGCGGTGAAGACGACGGACGAAGTGGCCGACCGCTTTGCCGATGCCCTGCCGGTCCTCGAT
CTCGACGACCTGCCCTACACCCCCGGACAGCCCGACGACGCGGGCGCGTTGCTGGCCCTGAACGCGCTGGCGACCGCCAC
CGGACTCGTCCGGTCGGGCGCCGCATCCGCCCTGGTCACCGGGCCCATCGCCAAGAGCCGTCTCGCGCGGGTCGGCTTCG
ACTTTCCGGGGCAGACGGAATTCGTGGCCGACGTCTGCGGGATCACCCCCGAACACGCGGTGATGATGCTGGCCGGGCCC
AGCCTGCGCGTCGTTCCCATCACCGTGCATGTCTCGCTGCGCAGCGTGCCCGACCTGCTTACCGTGGAACTCATCCGCAG
CCGCGCCGCCATCGCCGCTGCGGCGCTGGCGCGCGATTTCGGGATCGCCGCCCCCCGCCTCGCCGTCGCCGGGCTGAACC
CGCATGCGGGCGAGGACGGCCGCATGGGCACCGAAGACGGCGCGATCGTCGCCCCGGCCGTGGCGGCTCTGCGCGAAGCC
GGGATCGACGCCTTCGGCCCGCTCCCGCCCGACACCATGTTCCACGCCGAAGCGCGCGAGCGCTATGACGCAGCCATCTG
CATGTACCACGACCAGGCACTCATCCCGATGAAGGCGCTGGATTTCGACGAAGGCGTGAACGTCACGCTCGGCCTGCCGA
TCATCCGCACTTCGCCCGACCACGGCACCGCGTTCGCCATCGCCGGCACGGGCACCGCACGCGTCGGTCCGACAATCGCG
GCGATCCGGATGGCAGGCGAATGCGCCAAACGGAGGGCCATGCCATGA

Upstream 100 bases:

>100_bases
GACGCGGTGATCGAGTACAACTGAGGAAGTCCTGGGACTGGCCGGAACACTCTCGGCCAGTACCCTCGCAATGCGCGGCG
GCTTGGTCTAGGGGTCGGCC

Downstream 100 bases:

>100_bases
CCGACCTTCCCCCCCTGCGCGACGTCGTCAACCGTCACGGCCTCTACGCAACCAAGGCCCTGGGGCAGAACTTCCTGTTC
GACGAGCAGTTGCTCGACCG

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTALAPLALTIGDPAGVGPELAAAAWALSDAEALLPFFVVGSARVVEEAARRRGITVPVCAVKTTDEVADRFADALPVLD
LDDLPYTPGQPDDAGALLALNALATATGLVRSGAASALVTGPIAKSRLARVGFDFPGQTEFVADVCGITPEHAVMMLAGP
SLRVVPITVHVSLRSVPDLLTVELIRSRAAIAAAALARDFGIAAPRLAVAGLNPHAGEDGRMGTEDGAIVAPAVAALREA
GIDAFGPLPPDTMFHAEARERYDAAICMYHDQALIPMKALDFDEGVNVTLGLPIIRTSPDHGTAFAIAGTGTARVGPTIA
AIRMAGECAKRRAMP

Sequences:

>Translated_335_residues
MTALAPLALTIGDPAGVGPELAAAAWALSDAEALLPFFVVGSARVVEEAARRRGITVPVCAVKTTDEVADRFADALPVLD
LDDLPYTPGQPDDAGALLALNALATATGLVRSGAASALVTGPIAKSRLARVGFDFPGQTEFVADVCGITPEHAVMMLAGP
SLRVVPITVHVSLRSVPDLLTVELIRSRAAIAAAALARDFGIAAPRLAVAGLNPHAGEDGRMGTEDGAIVAPAVAALREA
GIDAFGPLPPDTMFHAEARERYDAAICMYHDQALIPMKALDFDEGVNVTLGLPIIRTSPDHGTAFAIAGTGTARVGPTIA
AIRMAGECAKRRAMP
>Mature_334_residues
TALAPLALTIGDPAGVGPELAAAAWALSDAEALLPFFVVGSARVVEEAARRRGITVPVCAVKTTDEVADRFADALPVLDL
DDLPYTPGQPDDAGALLALNALATATGLVRSGAASALVTGPIAKSRLARVGFDFPGQTEFVADVCGITPEHAVMMLAGPS
LRVVPITVHVSLRSVPDLLTVELIRSRAAIAAAALARDFGIAAPRLAVAGLNPHAGEDGRMGTEDGAIVAPAVAALREAG
IDAFGPLPPDTMFHAEARERYDAAICMYHDQALIPMKALDFDEGVNVTLGLPIIRTSPDHGTAFAIAGTGTARVGPTIAA
IRMAGECAKRRAMP

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=326, Percent_Identity=37.7300613496933, Blast_Score=187, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 34443; Mature: 34312

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALAPLALTIGDPAGVGPELAAAAWALSDAEALLPFFVVGSARVVEEAARRRGITVPVC
CCCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHCCCEEEEE
AVKTTDEVADRFADALPVLDLDDLPYTPGQPDDAGALLALNALATATGLVRSGAASALVT
EECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
GPIAKSRLARVGFDFPGQTEFVADVCGITPEHAVMMLAGPSLRVVPITVHVSLRSVPDLL
CCHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCEEEEEEEEEEEECCCCHHH
TVELIRSRAAIAAAALARDFGIAAPRLAVAGLNPHAGEDGRMGTEDGAIVAPAVAALREA
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
GIDAFGPLPPDTMFHAEARERYDAAICMYHDQALIPMKALDFDEGVNVTLGLPIIRTSPD
CCCCCCCCCCCCEEHHHHHHHCCEEEEEEECCCCCCHHHCCCCCCCEEEECCEEEEECCC
HGTAFAIAGTGTARVGPTIAAIRMAGECAKRRAMP
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TALAPLALTIGDPAGVGPELAAAAWALSDAEALLPFFVVGSARVVEEAARRRGITVPVC
CCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHCCCEEEEE
AVKTTDEVADRFADALPVLDLDDLPYTPGQPDDAGALLALNALATATGLVRSGAASALVT
EECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
GPIAKSRLARVGFDFPGQTEFVADVCGITPEHAVMMLAGPSLRVVPITVHVSLRSVPDLL
CCHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCEEEEEEEEEEEECCCCHHH
TVELIRSRAAIAAAALARDFGIAAPRLAVAGLNPHAGEDGRMGTEDGAIVAPAVAALREA
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
GIDAFGPLPPDTMFHAEARERYDAAICMYHDQALIPMKALDFDEGVNVTLGLPIIRTSPD
CCCCCCCCCCCCEEHHHHHHHCCEEEEEEECCCCCCHHHCCCCCCCEEEECCEEEEECCC
HGTAFAIAGTGTARVGPTIAAIRMAGECAKRRAMP
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA